Lack of association between cathepsin D C224T polymorphism and Alzheimer's disease risk: an update meta-analysis

scientific article published on 15 January 2014

Lack of association between cathepsin D C224T polymorphism and Alzheimer's disease risk: an update meta-analysis is …
instance of (P31):
scholarly articleQ13442814
meta-analysisQ815382

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P6179Dimensions Publication ID1038320114
P356DOI10.1186/1471-2377-14-13
P932PMC publication ID3901763
P698PubMed publication ID24423188
P5875ResearchGate publication ID259723501

P2093author name stringShan Li
Jian Wang
Qiliu Peng
Xue Qin
Yan Deng
Li Xie
Yu He
Cuiju Mo
Jingzhe Sui
Taijie Li
P2860cites workGene expression and cellular content of cathepsin D in Alzheimer's disease brain: Evidence for early up-regulation of the endosomal-lysosomal systemQ53312341
Genetic polymorphism of cathepsin D is strongly associated with the risk for developing sporadic Alzheimer's disease.Q53335124
Cathepsin D gene exon 2 polymorphism and sporadic Alzheimer's disease.Q53337389
Interaction of two genes possibly involved in the regulation of the amyloid precursor protein (APP) processing.Q53341909
The genetic association between Cathepsin D and Alzheimer's disease.Q53341998
Cathepsin D polymorphism not associated with Alzheimer's disease in Japanese.Q53346297
Lack of association of cathepsin D genetic polymorphism with Alzheimer's disease in Koreans.Q53372950
The cathepsin D gene exon 2 (C224T) polymorphism and sporadic Alzheimer's disease in European populations.Q53373401
Cathepsin D exon 2 polymorphism associated with general intelligence in a healthy older populationQ57306872
Short arm of chromosome 11 and sporadic Alzheimer's disease: Catalase and cathepsin D gene polymorphismsQ58005927
Missense polymorphism (C/T224) in the human cathepsin D pro-fragment determined by polymerase chain reaction--single strand conformational polymorphism analysis and possible consequences in cancer cellsQ72520156
Membership in genetic groups predicts Alzheimer diseaseQ83142218
Age at onset: an essential variable for the definition of genetic risk factors for sporadic Alzheimer's diseaseQ95811787
Non-replication of association between cathepsin D genotype and late onset Alzheimer diseaseQ28212717
Interaction of CTSD and A2M polymorphisms in the risk for Alzheimer's diseaseQ28247008
Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene databaseQ28280965
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African AmericansQ30540165
In vitro processing of amyloid precursor protein by cathepsin D.Q30828285
Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer diseaseQ33582860
Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrumQ33870467
SNP association studies in Alzheimer's disease highlight problems for complex disease analysis.Q34288840
Putative association of polymorphism in the mannose 6-phosphate receptor gene with major depression and Alzheimer's diseaseQ34323483
Meta-analysis of the association of the cathepsin D Ala224Val gene polymorphism with the risk of Alzheimer's disease: a HuGE gene-disease association reviewQ35683709
Autocrine and paracrine calcium signaling by the CD38/NAD+/cyclic ADP-ribose systemQ36009179
Genetic associations between cathepsin D exon 2 C-->T polymorphism and Alzheimer's disease, and pathological correlations with genotypeQ36142328
Replication of BIN1 association with Alzheimer's disease and evaluation of genetic interactionsQ36371829
Towards compendia of negative genetic association studies: an example for Alzheimer diseaseQ40366237
Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's diseaseQ43661047
Lack of association between cathepsin D genetic polymorphism and Alzheimer disease in a Spanish sampleQ43882959
Cathepsin D polymorphism in Italian elderly subjects with sporadic late-onset Alzheimer's diseaseQ44031460
Cathepsin D polymorphism in Italian sporadic and familial Alzheimer's diseaseQ44082468
Cerebrospinal fluid levels of beta-amyloid(42) in patients with Alzheimer's disease are related to the exon 2 polymorphism of the cathepsin D geneQ44085408
Association between cathepsin D polymorphism and Alzheimer's disease in a Chinese Han populationQ44947294
Cathepsin D gene and the risk of Alzheimer's disease: a population-based study and meta-analysis.Q46027686
DAPK1 variants are associated with Alzheimer's disease and allele-specific expressionQ48085987
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's diseaseQ48181387
Rates and risk factors for dementia and Alzheimer's disease: results from EURODEM pooled analyses. EURODEM Incidence Research Group and Work Groups. European Studies of Dementia.Q50537933
The relationships between age, sex, and the incidence of dementia and Alzheimer disease: a meta-analysis.Q50866744
Occurrence of cognitive impairment and dementia in the community: a 9-year-long prospective study.Q51897110
Frequency and distribution of Alzheimer's disease in Europe: a collaborative study of 1980-1990 prevalence findings. The EURODEM-Prevalence Research Group.Q52048616
Immunodetection of cathepsin D in neuritic plaques found in brains of patients with dementia of Alzheimer type.Q53187500
A genetic variation of cathepsin D is a major risk factor for Alzheimer's disease.Q53233672
Genetic polymorphisms in the cathespin D and interleukin-6 genes and the risk of Alzheimer's disease.Q53236131
No evidence for genetic association or linkage of the cathepsin D (CTSD) exon 2 polymorphism and Alzheimer disease.Q53240455
Simultaneous analysis of five genetic risk factors in Polish patients with Alzheimer's disease.Q53254725
[The C224T polymorphism in the cathepsin D gene is not associated with sporadic Alzheimer's disease in Chinese].Q53269160
The cathepsin D (224C/T) polymorphism confers an increased risk to develop Alzheimer's disease in men.Q53307121
P921main subjectAlzheimer's diseaseQ11081
P304page(s)13
P577publication date2014-01-15
P1433published inBMC NeurologyQ15763734
P1476titleLack of association between cathepsin D C224T polymorphism and Alzheimer's disease risk: an update meta-analysis
P478volume14

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cites work (P2860)
Q50023771Autophagy and Alzheimer's Disease: From Molecular Mechanisms to Therapeutic Implications
Q38817664The Role of Cathepsin D in the Pathogenesis of Human Neurodegenerative Disorders.

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