The immunological characteristics and probiotic function of recombinant Bacillus subtilis spore expressing Clonorchis sinensis cysteine protease

scientific article published on 19 December 2016

The immunological characteristics and probiotic function of recombinant Bacillus subtilis spore expressing Clonorchis sinensis cysteine protease is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1001565133
P356DOI10.1186/S13071-016-1928-0
P932PMC publication ID5170900
P698PubMed publication ID27993173

P50authorXuerong LiQ121769933
P2093author name stringYan Huang
Xinbing Yu
Jin Xu
Zhipeng Lin
Lina Zhou
Hongling Qu
Hengchang Sun
Tingjin Chen
Mei Shang
Hongye Jiang
Pengli Ren
Xinyi Zhou
Zeli Tang
Jinyun Yu
P2860cites workThe draft genome of the carcinogenic human liver fluke Clonorchis sinensisQ22065287
Secretory IgA's complex roles in immunity and mucosal homeostasis in the gutQ24620817
Histological grading and staging of chronic hepatitisQ29619625
Oral administration of a Bacillus subtilis spore-based vaccine expressing Clonorchis sinensis tegumental protein 22.3 kDa confers protection against Clonorchis sinensisQ33323145
Intestinal mucins in colonization and host defense against pathogensQ33645456
Molecular characterization and expression of a cysteine protease from Clonorchis sinensis and its application for serodiagnosis of clonorchiasisQ34101367
Intestinal goblet cells and mucins in health and disease: recent insights and progressQ34102377
Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of wormsQ34318119
Clonorchiasis: a key foodborne zoonosis in ChinaQ34379923
IgA responses in the intestinal mucosa against pathogenic and non-pathogenic microorganisms.Q34387806
Effect of probiotic administration on the intestinal microbiota, current knowledge and potential applicationsQ34589700
The diagnosis of human fascioliasis by enzyme-linked immunosorbent assay (ELISA) using recombinant cathepsin L proteaseQ34999829
Cysteine proteases and cell differentiation: excystment of the ciliated protist Sterkiella histriomuscorum.Q35696334
Protective Role of Purified Cysteine Proteinases against Fasciola gigantica Infection in Experimental AnimalsQ35842682
Bacillus subtilis: a temperature resistant and needle free delivery system of immunogensQ36391905
Utility of a protein fraction with cathepsin L-Like activity purified from cysticercus fluid of Taenia solium in the diagnosis of human cysticercosisQ37388322
Bacillus subtilis spores as vaccine adjuvants: further insights into the mechanisms of action.Q37521363
Gut adhesive Bacillus subtilis spores as a platform for mucosal delivery of antigens.Q37713305
Bacterial spores as platforms for bioanalytical and biomedical applicationsQ37850353
Global burden of human food-borne trematodiasis: a systematic review and meta-analysisQ37959784
The interactions between endogenous bacteria, dietary components and the mucus layer of the large bowel.Q38008242
Mucosal immunization: a review of strategies and challenges.Q38235027
The mucosal immune system for vaccine developmentQ38278302
Delivery strategies to enhance oral vaccination against enteric infections.Q38393940
ClonorchiasisQ38571961
The involvement of the cysteine proteases of Clonorchis sinensis metacercariae in excystmentQ39176737
Surface display of Clonorchis sinensis enolase on Bacillus subtilis spores potentializes an oral vaccine candidateQ39576505
The safety of Bacillus subtilis and Bacillus indicus as food probioticsQ40007198
Systemic and local mucosal immune responses induced by orally delivered Bacillus subtilis spore expressing leucine aminopeptidase 2 of Clonorchis sinensisQ42211666
Purification of a diagnostic, secreted cysteine protease-like protein from the hookworm Ancylostoma caninum.Q42637435
Early cysteine protease activity in excretory bladder triggers metacercaria excystment of Paragonimus westermaniQ43340614
Alteration of the expression profiles of acidic mucin, sialytransferase, and sulfotransferases in the intestinal epithelium of rats infected with the nematode Nippostrongylus brasiliensisQ50457429
Bacterial modulation of small intestinal goblet cells and mucin composition during early posthatch development of poultryQ50463754
Germination of the spore in the gastrointestinal tract provides a novel route for heterologous antigen deliveryQ52955327
Enhanced immunisation and expression strategies using bacterial spores as heat-stable vaccine delivery vehiclesQ53008898
Cysteine protease is a major component in the excretory/secretory products of Euclinostomum heterostomum (Digenea: Clinostomidae).Q53086187
IgG1 and IgG2a profile of serum antibodies to Leishmania major amastigote in BALB/c and C57BL/6MiceQ53125506
OVA-bound nanoparticles induce OVA-specific IgG1, IgG2a, and IgG2b responses with low IgE synthesisQ54340211
Oral delivery of Bacillus subtilis spore expressing enolase of Clonorchis sinensis in rat model: induce systemic and local mucosal immune responses and has no side effect on liver functionQ57106995
Protection from murine cysticercosis by immunization with a parasite cysteine proteaseQ58646511
Oral priming of mice by recombinant spores of Bacillus subtilisQ59592118
[Proteases in helminthic parasites.]Q64215474
Mucosal immunization using recombinant plant-based oral vaccinesQ82345610
P433issue1
P921main subjectprobioticsQ1816730
Bacillus subtilisQ131238
Clonorchis sinensisQ1074210
P304page(s)648
P577publication date2016-12-19
P1433published inParasites and VectorsQ7135941
P1476titleThe immunological characteristics and probiotic function of recombinant Bacillus subtilis spore expressing Clonorchis sinensis cysteine protease
P478volume9

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cites work (P2860)
Q57288901A 21.6 kDa tegumental protein of Clonorchis sinensis induces a Th1/Th2 mixed immune response in mice
Q51743332Bacillus subtilis spore with surface display of paramyosin from Clonorchis sinensis potentializes a promising oral vaccine candidate
Q33808636Clonorchis sinensis lysophospholipase A upregulates IL-25 expression in macrophages as a potential pathway to liver fibrosis
Q39605791Comparative analysis of immune effects in mice model: Clonorchis sinensis cysteine protease generated from recombinant Escherichia coli and Bacillus subtilis spores
Q94669192Evaluation of immune response to Bacillus subtilis spores expressing Clonorchis sinensis serpin3
Q59332933Mouse intestinal microbiota reduction favors local intestinal immunity triggered by antigens displayed in Bacillus subtilis biofilm

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