Intestinal goblet cells and mucins in health and disease: recent insights and progress

scientific article

Intestinal goblet cells and mucins in health and disease: recent insights and progress is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1044357370
P356DOI10.1007/S11894-010-0131-2
P932PMC publication ID2933006
P698PubMed publication ID20703838
P5875ResearchGate publication ID45630733

P2093author name stringSamuel B Ho
Young S Kim
P2860cites workpS2/TFF1 interacts directly with the VWFC cysteine-rich domains of mucinsQ22010982
Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp proteinQ24309654
MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive regionQ24318693
A human gut microbial gene catalogue established by metagenomic sequencingQ24618931
Bacteria penetrate the inner mucus layer before inflammation in the dextran sulfate colitis modelQ27321389
Molecular cloning of human intestinal mucin cDNAs. Sequence analysis and evidence for genetic polymorphismQ28115957
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseasesQ28131810
Mucin and Toll-like receptors in host defense against intestinal parasitesQ28186441
Mucins in cancer: protection and control of the cell surfaceQ28235006
Structure and function of the cell surface (tethered) mucinsQ28248285
Stem cells, self-renewal, and differentiation in the intestinal epitheliumQ28294807
Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitisQ28472412
Direct regulation of intestinal fate by NotchQ28507015
Glycosyltransferase function in core 2-type protein O glycosylationQ28509840
Colorectal cancer in mice genetically deficient in the mucin Muc2Q28588769
The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epitheliumQ28591094
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteriaQ28594441
Unravelling the pathogenesis of inflammatory bowel diseaseQ29547551
Microbial influences in inflammatory bowel diseasesQ29614264
Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protectionQ29618129
Structure and macromolecular properties of cervical mucus glycoproteinsQ38788786
MUC2 gene promoter methylation in mucinous and non-mucinous colorectal cancer tissues.Q39733021
MUC2 expression is regulated by histone H3 modification and DNA methylation in pancreatic cancerQ40276044
Expression of mucin core proteins, trefoil factors, APC and p21 in subsets of colorectal polyps and cancers suggests a distinct pathway of pathogenesis of mucinous carcinoma of the colorectum.Q40377409
TNF-alpha activates MUC2 transcription via NF-kappaB but inhibits via JNK activation.Q40467064
The recombinant C-terminus of the human MUC2 mucin forms dimers in Chinese-hamster ovary cells and heterodimers with full-length MUC2 in LS 174T cells.Q40669179
Probiotics inhibit enteropathogenic E. coli adherence in vitro by inducing intestinal mucin gene expression.Q40961532
Trefoil peptide protection of intestinal epithelial barrier function: cooperative interaction with mucin glycoproteinQ41319361
Intestinal mucins from cystic fibrosis mice show increased fucosylation due to an induced Fucalpha1-2 glycosyltransferaseQ42115743
Human intestinal TFF3 forms disulfide-linked heteromers with the mucus-associated FCGBP protein and is released by hydrogen sulfideQ43084158
Oscillations of pH inside the secretory granule control the gain of Ca2+ release for signal transduction in goblet cell exocytosisQ44303217
The gastric mucus layers: constituents and regulation of accumulationQ44357173
The adherent gastric mucous layer is composed of alternating layers of MUC5AC and MUC6 mucin proteinsQ45169701
Molecular cloning of human intestinal mucin (MUC2) cDNA. Identification of the amino terminus and overall sequence similarity to prepro-von Willebrand factor.Q46156562
BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than non-mucinous colorectal cancerQ46365032
Resistin-like molecule beta regulates intestinal mucous secretion and curtails TNBS-induced colitis in miceQ46733337
Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminusQ48229568
Cysteine-rich domains of muc3 intestinal mucin promote cell migration, inhibit apoptosis, and accelerate wound healing.Q54452038
Cystic fibrosisQ55881299
Goblet cell mucins as the selective barrier for the intestinal helminths: T-cell-independent alteration of goblet cell mucins by immunologically 'damaged' Nippostrongylus brasiliensis worms and its significance on the challenge infection with homoloQ72525418
mRNA of MUC2 is stimulated by IL-4, IL-13 or TNF-alpha through a mitogen-activated protein kinase pathway in human colon cancer cellsQ73631158
The adherent gastrointestinal mucus gel layer: thickness and physical state in vivoQ73727591
Effects of laxative and N-acetylcysteine on mucus accumulation, bacterial load, transit, and inflammation in the cystic fibrosis mouse small intestineQ80576316
Aberrant expression of carbohydrate antigens in cancer: the role of genetic and epigenetic regulationQ95793699
The N terminus of the MUC2 mucin forms trimers that are held together within a trypsin-resistant core fragment.Q30861929
Lineage commitment and maturation of epithelial cells in the gut.Q33541264
Intestinal epithelial cell secretion of RELM-beta protects against gastrointestinal worm infectionQ33590452
Goblet cell-derived resistin-like molecule beta augments CD4+ T cell production of IFN-gamma and infection-induced intestinal inflammationQ33642117
Pathogen recognition receptors, cancer and inflammation in the gut.Q33680511
Human intestinal MUC17 mucin augments intestinal cell restitution and enhances healing of experimental colitisQ34056835
Requirement of Math1 for secretory cell lineage commitment in the mouse intestineQ34104685
Microbial modulation of innate defense: goblet cells and the intestinal mucus layer.Q34274121
How the gut senses its content.Q34565124
HATH1 expression in mucinous cancers of the colorectum and related lesionsQ34568757
The front line of enteric host defense against unwelcome intrusion of harmful microorganisms: mucins, antimicrobial peptides, and microbiotaQ34647328
Entamoeba histolytica cysteine proteases cleave the MUC2 mucin in its C-terminal domain and dissolve the protective colonic mucus gel.Q34695073
Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiencyQ34966525
Trefoil factors: initiators of mucosal healingQ35542021
Distribution and partial characterisation of IgG Fc binding protein in various mucin producing cells and body fluidsQ35594862
Resistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibilityQ35641138
Mucins and mucin binding proteins in colorectal cancerQ35682100
MUC1 cell surface mucin is a critical element of the mucosal barrier to infectionQ35879509
Activation of NF-kappaB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cellsQ36097177
Regulation of airway mucin gene expressionQ36216587
Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycansQ36229430
Mucin gene deficiency in mice impairs host resistance to an enteric parasitic infection.Q36303831
Regulation of mucin expression: mechanistic aspects and implications for cancer and inflammatory diseasesQ36400087
Molecular signaling in the regulation of mucinsQ36980458
Regulated airway goblet cell mucin secretion.Q36995541
Innate immune response mechanisms in the intestinal epithelium: potential roles for mast cells and goblet cells in the expulsion of adult Trichinella spiralisQ37138677
Intestinal barrier dysfunction in inflammatory bowel diseases.Q37214839
Coordinate regulation of glycan degradation and polysaccharide capsule biosynthesis by a prominent human gut symbiontQ37258564
Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator-dependent bicarbonate secretionQ37328491
The trefoil factor family - small peptides with multiple functionalitiesQ37355821
Unraveling mechanisms of action of probiotics.Q37401581
RELMbeta/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tractQ37535131
Role of intestinal mucins in innate host defense mechanisms against pathogensQ37726707
Vasoactive intestinal peptide upregulates MUC2 intestinal mucin via CREB/ATF1.Q38319884
P433issue5
P921main subjectcellQ7868
respiratory systemQ7891
human digestive systemQ9649
tissueQ40397
mucoproteinsQ1983390
P304page(s)319-330
P577publication date2010-10-01
P1433published inCurrent gastroenterology reportsQ26842032
P1476titleIntestinal goblet cells and mucins in health and disease: recent insights and progress
P478volume12

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cites work (P2860)
Q35969999A Microbial Feed Additive Abates Intestinal Inflammation in Atlantic Salmon
Q64884142A Sensitive and Rapid Method to Determin the Adhesion Capacity of Probiotics and Pathogenic Microorganisms to Human Gastrointestinal Mucins.
Q34796803A comprehensive expression analysis of mucins in appendiceal carcinoma in a multicenter study: MUC3 is a novel prognostic factor
Q41750028A guide to histomorphological evaluation of intestinal inflammation in mouse models.
Q35094605A metagenomic approach to characterize temperate bacteriophage populations from Cystic Fibrosis and non-Cystic Fibrosis bronchiectasis patients
Q35075430A subset of mouse colonic goblet cells expresses the bitter taste receptor Tas2r131
Q91973669A theoretical model of temperate phages as mediators of gut microbiome dysbiosis
Q41567299AMP-activated protein kinase: a therapeutic target in intestinal diseases.
Q33931221Activation of epidermal growth factor receptor mediates mucin production stimulated by p40, a Lactobacillus rhamnosus GG-derived protein
Q55613955Acute Exposure to Commonly Ingested Emulsifiers Alters Intestinal Mucus Structure and Transport Properties.
Q45217658Adherence of bacteria to mucus collected from different parts of the reproductive tract of heifers and cows.
Q35831349Administration of defined microbiota is protective in a murine Salmonella infection model.
Q57173560Advancing risk assessment: mechanistic dose-response modelling of infection in human populations
Q53184434Alterations of epithelial layer after ischemic preconditioning of small intestine in rats.
Q34782538Altered innate defenses in the neonatal gastrointestinal tract in response to colonization by neuropathogenic Escherichia coli.
Q37871646Always one step ahead: How pathogenic bacteria use the type III secretion system to manipulate the intestinal mucosal immune system
Q48939479An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice.
Q92427378Analysis of glycoconjugates and morphological characterization of the descending colon and rectum of the plains viscacha, Lagostomus maximus
Q89619909Anti-Inflammatory Effects of Huangqin Decoction on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice Through Regulation of the Gut Microbiota and Suppression of the Ras-PI3K-Akt-HIF-1α and NF-κB Pathways
Q37712802Anti-infective activities of lactobacillus strains in the human intestinal microbiota: from probiotics to gastrointestinal anti-infectious biotherapeutic agents
Q36277657Antibiotics, gut microbiota, environment in early life and type 1 diabetes.
Q35995535Antimicrobial aspects of inflammatory resolution in the mucosa: a role for proresolving mediators
Q38018004Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium
Q34626921Bacillus cereus var. toyoi promotes growth, affects the histological organization and microbiota of the intestinal mucosa in rainbow trout fingerlings.
Q47110338Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium.
Q34732850Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent
Q34663532Behavior of lactobacilli isolated from fermented slurry (ben-saalga) in gnotobiotic rats
Q47550706Beneficial effects of consumption of acerola, cashew or guava processing by-products on intestinal health and lipid metabolism in dyslipidaemic female Wistar rats
Q42930149BopA does not have a major role in the adhesion of Bifidobacterium bifidum to intestinal epithelial cells, extracellular matrix proteins, and mucus.
Q40722271Brain injury induces specific changes in the caecal microbiota of mice via altered autonomic activity and mucoprotein production
Q40071271Butyrate Supplementation at High Concentrations Alters Enteric Bacterial Communities and Reduces Intestinal Inflammation in Mice Infected with Citrobacter rodentium
Q41927515Butyrate modulates bacterial adherence on LS174T human colorectal cells by stimulating mucin secretion and MAPK signaling pathway
Q38163518CELL BIOLOGY SYMPOSIUM: Impacts of maternal obesity on placental and gut inflammation and health
Q46693539Cape Gooseberry [Physalis peruviana L.] Calyces Ameliorate TNBS Acid-induced Colitis in Rats.
Q64109975Cellular and Molecular Therapeutic Targets in Inflammatory Bowel Disease-Focusing on Intestinal Barrier Function
Q64078780Challenge to the Intestinal Mucosa During Sepsis
Q33718291Changes in iron transporter divalent metal transporter 1 in proximal jejunum after gastric bypass
Q33837769Coherent somatic mutation in autoimmune disease
Q27306052Commensal Akkermansia muciniphila exacerbates gut inflammation in Salmonella Typhimurium-infected gnotobiotic mice
Q38026391Commensal-innate immune miscommunication in IBD pathogenesis
Q39967200Comparative Analysis of the Morphology, Ultrastructure, and Glycosylation Pattern of the Jejunum and Ileum of the Wild Rodent Lagostomus maximus
Q89339031Conjunctival cytologic features in patients with unilateral primary acquired nasolacrimal duct obstruction
Q41379177Core 2 Mucin-Type O-Glycan Is Related to EPEC and EHEC O157:H7 Adherence to Human Colon Carcinoma HT-29 Epithelial Cells
Q47094912Could Mycobacterium avium subspecies paratuberculosis cause Crohn’s disease, ulcerative colitis…and colorectal cancer?
Q92755015Current understanding of the gut microbiota shaping mechanisms
Q98177224Cutibacterium acnes regulates the epidermal barrier properties of HPV-KER human immortalized keratinocyte cultures
Q98290847Cyclic nigerosylnigerose ameliorates DSS-induced colitis with restoration of goblet cell number and increase in IgA reactivity against gut microbiota in mice
Q37947605Cytokine-induced alterations of gastrointestinal motility in gastrointestinal disorders
Q38987729Cytotoxicity and metabolic stress induced by acetaldehyde in human intestinal LS174T goblet-like cells
Q38850512Death in the intestinal epithelium-basic biology and implications for inflammatory bowel disease.
Q42364790Decoding Hidden Messages: Can Fecal Host Transcriptomics Open Pathways to Understanding Environmental Enteropathy?
Q92901409Deficiency of Dietary Fiber in Slc5a8-Null Mice Promotes Bacterial Dysbiosis and Alters Colonic Epithelial Transcriptome towards Proinflammatory Milieu
Q41457929Deoxynivalenol inhibits the expression by goblet cells of intestinal mucins through a PKR and MAP kinase dependent repression of the resistin-like molecule β.
Q51001933Depletion of enteroendocrine and mucus-secreting cells is associated with colorectal carcinogenesis severity and impaired intestinal motility in rats.
Q90194902Development of Salmonellosis as Affected by Bioactive Food Compounds
Q104135111Development of a human primary gut-on-a-chip to model inflammatory processes
Q47686064Development of a total colectomy and ileorectal anastomosis rat model to evaluate colonic metaplasia
Q92881337Dietary High Sodium Fluoride Impairs Digestion and Absorption Ability, Mucosal Immunity, and Alters Cecum Microbial Community of Laying Hens
Q90268325Dietary corn resistant starch regulates intestinal morphology and barrier functions by activating the Notch signaling pathway of broilers
Q89941237Dietary encapsulated essential oils and organic acids mixture improves gut health in broiler chickens challenged with necrotic enteritis
Q51687929Dietary fucoidan modulates the gut microbiota in mice by increasing the abundance of Lactobacillus and Ruminococcaceae.
Q53539472Dietary intervention with serum-derived bovine immunoglobulins protects barrier function in a mouse model of colitis.
Q57100701Dietary l-threonine supplementation attenuates lipopolysaccharide-induced inflammatory responses and intestinal barrier damage of broiler chickens at an early age
Q58714488Dietary magnesium deficiency impaired intestinal structural integrity in grass carp (Ctenopharyngodon idella)
Q57067863Differential expression of mucin 1 and mucin 2 in colorectal cancer
Q34635939Differential expression of mucosal trefoil factors and mucins in pediatric inflammatory bowel diseases.
Q38650504Differential intestinal anti-inflammatory effects of Lactobacillus fermentum and Lactobacillus salivarius in DSS mouse colitis: impact on microRNAs expression and microbiota composition.
Q90064947Differentiation of human colon tissue in culture: Effects of calcium on trans-epithelial electrical resistance and tissue cohesive properties
Q35913346Diterpenoid alkaloids of Aconitum laciniatum and mitigation of inflammation by 14-O-acetylneoline in a murine model of ulcerative colitis.
Q28551245Dose-Response Analysis of Chemotactic Signaling Response in Salmonella typhimurium LT2 upon Exposure to Cysteine/Cystine Redox Pair
Q39876741Down-regulation of mechanisms involved in cell transport and maintenance of mucosal integrity in pigs infected with Lawsonia intracellularis.
Q28585735E-cadherin is required for intestinal morphogenesis in the mouse
Q52596112Early Life Thermal Stress: Impact on Future Thermotolerance, Stress Response, Behavior, and Intestinal Morphology in Piglets Exposed to a Heat Stress Challenge During Simulated Transport.
Q37626305Early commitment and robust differentiation in colonic crypts
Q50589903Early intestinal growth and development in poultry.
Q36941759Effect of a Semi-Purified Oligosaccharide-Enriched Fraction from Caprine Milk on Barrier Integrity and Mucin Production of Co-Culture Models of the Small and Large Intestinal Epithelium
Q48315419Effect of carrageenans alone and in combination with casein or lipopolysaccharide on human epithelial intestinal HT-29 cells
Q58597191Effects of 17β-Estradiol on Colonic Permeability and Inflammation in an Azoxymethane/Dextran Sulfate Sodium-Induced Colitis Mouse Model
Q49916765Effects of Bacillus coagulans supplementation on the growth performance and gut health of broiler chickens with Clostridium perfringens-induced necrotic enteritis
Q57700541Effects of Enteromyxum leei (Myxozoa) infection on gilthead sea bream (Sparus aurata) (Teleostei) intestinal mucus: glycoprotein profile and bacterial adhesion
Q35972381Effects of Weaning on Intestinal Upper Villus Epithelial Cells of Piglets
Q98946343Effects of a ready-to-eat cereal formula powder on glucose metabolism, inflammation, and gut microbiota in diabetic db/db mice
Q38731494Effects of arginine on intestinal epithelial cell integrity and nutrient uptake
Q51732444Effects of dietary Bacillus amyloliquefaciens supplementation on growth performance, intestinal morphology, inflammatory response, and microbiota of intra-uterine growth retarded weanling piglets.
Q90138759Effects of dietary fiber and threonine on performance, intestinal morphology and immune responses in broiler chickens
Q90213901Effects of dietary yeast beta-1,3-1,6-glucan on growth performance, intestinal morphology and chosen immunity parameters changes in Haidong chicks
Q89533164Effects of feed removal on thermoregulation and intestinal morphology in pigs recovering from acute hyperthermia
Q52844298Effects of feeding transgenic corn with mCry1Ac or maroACC gene to laying hens for 12 weeks on growth, egg quality and organ health.
Q35251212Effects of hemin and nitrite on intestinal tumorigenesis in the A/J Min/+ mouse model
Q45325304Effects of porcine epidemic diarrhea virus infection on nursery pig intestinal function and barrier integrity.
Q39558095Effects of potato fiber and potato-resistant starch on biomarkers of colonic health in rats fed diets containing red meat
Q52723947Effects of short-term feeding of Bt MON810 maize on growth performance, organ morphology and function in pigs.
Q39012302Emerging treatments in Neurogastroenterology: Perspectives of guanylyl cyclase C agonists use in functional gastrointestinal disorders and inflammatory bowel diseases
Q36635893Enhanced membrane-tethered mucin 3 (MUC3) expression by a tetrameric branched peptide with a conserved TFLK motif inhibits bacteria adherence
Q33560794Enrichment of in vivo transcription data from dietary intervention studies with in vitro data provides improved insight into gene regulation mechanisms in the intestinal mucosa.
Q28821607Enteric Pathogens Exploit the Microbiota-generated Nutritional Environment of the Gut
Q58084889Enteric infection coupled with chronic Notch pathway inhibition alters colonic mucus composition leading to dysbiosis, barrier disruption and colitis
Q35558450Epigenetic modifications of the immune system in health and disease
Q47129733Epithelial Barrier Function in Gut-Bone Signaling.
Q51081156Epithelial cell types and their proposed roles in maintaining the mucosal barrier in human chagasic-megacolonic mucosa.
Q64254117Establishment and Characterization of 5-Fluorouracil-Resistant Human Colorectal Cancer Stem-Like Cells: Tumor Dynamics under Selection Pressure
Q91711356Evaluating the Causal Role of Gut Microbiota in Type 1 Diabetes and Its Possible Pathogenic Mechanisms
Q38928542Evaluation of gamma ray-induced gastrointestinal tract morphological and proliferative activity changes in rhesus monkeys
Q30252163Evidence for the effects of yogurt on gut health and obesity.
Q39113167Evolutionary and ecological forces that shape the bacterial communities of the human gut.
Q58478064Expression of trefoil factor genes in the duodenum and colon of dogs with inflammatory bowel disease and healthy dogs
Q48250090Expression profiling of Tas2r genes reveals a complex pattern along the mouse GI tract and the presence of Tas2r131 in a subset of intestinal Paneth cells
Q93053999Fibroblasts Impact Goblet Cell Responses to Lactic Acid Bacteria After Exposure to Inflammatory Cytokines and Mucus Disruptors
Q36335964Finishing pigs that are divergent in feed efficiency show small differences in intestinal functionality and structure
Q38287036Food derived bioactive peptides and intestinal barrier function.
Q37014357Functional Genomic Analysis of the Impact of Camelina (Camelina sativa) Meal on Atlantic Salmon (Salmo salar) Distal Intestine Gene Expression and Physiology.
Q52345522Functional macrophages and gastrointestinal disorders.
Q40895257Galacto-oligosaccharides Protect the Intestinal Barrier by Maintaining the Tight Junction Network and Modulating the Inflammatory Responses after a Challenge with the Mycotoxin Deoxynivalenol in Human Caco-2 Cell Monolayers and B6C3F1 Mice
Q38938168Galacto-oligosaccharides may directly enhance intestinal barrier function through the modulation of goblet cells
Q39116552Gastrointestinal immune and microbiome changes during parenteral nutrition.
Q47835525Genetic and Transcriptomic Bases of Intestinal Epithelial Barrier Dysfunction in Inflammatory Bowel Disease.
Q47136145Genome-wide analysis of Atlantic salmon (Salmo salar) mucin genes and their role as biomarkers
Q52961939Giemsa-based cytological assessment of area, shape and nucleus:cytoplasm ratio of goblet cells of rabbit bulbar conjunctiva.
Q41438448Ginger and cinnamon: can this household remedy treat giardiasis? Parasitological and histopathological studies
Q38794312Gleaning Insights from Fecal Microbiota Transplantation and Probiotic Studies for the Rational Design of Combination Microbial Therapies.
Q27318038Goblet Cell Derived RELM-β Recruits CD4+ T Cells during Infectious Colitis to Promote Protective Intestinal Epithelial Cell Proliferation
Q54230553Goblet cells and mucin related gene expression in mice infected with Eimeria papillata.
Q26822449Goblet cells and mucins: role in innate defense in enteric infections
Q38811416Goblet cells of the conjunctiva: A review of recent findings
Q88985298Goblet cells: multifaceted players in immunity at mucosal surfaces
Q89805722Gut Microbiota, Antibiotic Therapy and Antimicrobial Resistance: A Narrative Review
Q35105266Gut ecosystem: how microbes help us.
Q26773267Gut epithelial barrier dysfunction in human immunodeficiency virus-hepatitis C virus coinfected patients: Influence on innate and acquired immunity
Q38878477Gut microbiota and hematopoietic stem cell transplantation: where do we stand?
Q41842167Gut-Associated Lymphoid Tissue: A Key Tissue Inside the Mucosal Immune System of Hens Immunized with Escherichia coli F4.
Q39333658Gut-liver axis, cirrhosis and portal hypertension: the chicken and the egg.
Q34989302HDAC1 and HDAC2 restrain the intestinal inflammatory response by regulating intestinal epithelial cell differentiation
Q33867430Helminths in the gastrointestinal tract as modulators of immunity and pathology.
Q35679581High Incubation Temperature and Threonine Dietary Level Improve Ileum Response Against Post-Hatch Salmonella Enteritidis Inoculation in Broiler Chicks
Q35615264High throughput sequencing reveals distinct microbial populations within the mucosal and luminal niches in healthy individuals
Q40343417High-resolution FTIR imaging of colon tissues for elucidation of individual cellular and histopathological features
Q37381713Histological assessments of intestinal immuno-morphology of tiger grouper juvenile, Epinephelus fuscoguttatus
Q33715804Homeostasis of the gut barrier and potential biomarkers
Q38852263Host inflammatory response inhibits Escherichia coli O157:H7 adhesion to gut epithelium through augmentation of mucin expression
Q92608559Houttuynia cordata polysaccharide alleviated intestinal injury and modulated intestinal microbiota in H1N1 virus infected mice
Q35576559Human Clostridium difficile infection: altered mucus production and composition
Q91690955Human Milk Oligosaccharides Differently Modulate Goblet Cells Under Homeostatic, Proinflammatory Conditions and ER Stress
Q35018086IL-22 mediates goblet cell hyperplasia and worm expulsion in intestinal helminth infection
Q36353243Identification of Potential Biomarkers for Gut Barrier Failure in Broiler Chickens
Q90429502Immune system stimulation increases dietary threonine requirements for protein deposition in growing pigs
Q57453405Immune system stimulation induced by Escherichia coli lipopolysaccharide alters plasma free amino acid flux and dietary nitrogen utilization in growing pigs
Q52552436Immunopathophysiology of inflammatory bowel disease: how genetics link barrier dysfunction and innate immunity to inflammation.
Q35825870Importance and regulation of the colonic mucus barrier in a mouse model of colitis
Q92016810Improved utilization of soybean meal through fermentation with commensal Shewanella sp. MR-7 in turbot (Scophthalmus maximus L.).
Q90099759Improvement of Feed Efficiency in Pigs through Microbial Modulation via Fecal Microbiota Transplantation in Sows and Dietary Supplementation of Inulin in Offspring
Q91828099In Vitro Intestinal Uptake And Permeability Of Fluorescently-Labelled Hyaluronic Acid Nanogels
Q89661521In Vitro Models of the Small Intestine: Engineering Challenges and Engineering Solutions
Q30842046In vivo imaging of the Muc5b gel-forming mucin
Q38374165Induction of protection in murine experimental models against Trichinella spiralis: an up-to-date review
Q90206040Inflammasomes in Colitis and Colorectal Cancer: Mechanism of Action and Therapies
Q38902578Inflammation and the Intestinal Barrier: Leukocyte-Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair
Q42688430Inflammatory Bowel Disease in Asia: A Second Chance at Uncovering Environmental Factors
Q37258771Inflammatory bowel disease: mechanisms, redox considerations, and therapeutic targets.
Q39439937Inflammatory cues modulate the expression of secretory product genes, Golgi sulfotransferases and sulfomucin production in LS174T cells.
Q39345514Influence of adhesion and bacteriocin production by Lactobacillus salivarius on the intestinal epithelial cell transcriptional response
Q47349740Injury and mechanism of recombinant E.coli expressing STa on piglets colon
Q92594507Innate Lymphoid Cells: Regulators of Gut Barrier Function and Immune Homeostasis
Q41479687Innate immunity modulation by the IL-33/ST2 system in intestinal mucosa
Q41386825Interaction of IFN-γ with cholinergic agonists to modulate rat and human goblet cell function.
Q41450553Interactions of Intestinal Bacteria with Components of the Intestinal Mucus
Q90726659Interactions of commensal and pathogenic microorganisms with the mucus layer in the colon
Q92173384International Society of Sports Nutrition Position Stand: Probiotics
Q47104587Intestinal Epithelial Cell Endoplasmic Reticulum Stress and Inflammatory Bowel Disease Pathogenesis: An Update Review
Q37399380Intestinal Metrnl released into the gut lumen acts as a local regulator for gut antimicrobial peptides
Q61811077Intestinal Microbiota as a Host Defense Mechanism to Infectious Threats
Q41024376Intestinal anti-inflammatory activity of Ground Cherry (Physalis angulata L.) standardized CO2 phytopharmaceutical preparation.
Q37413157Intestinal anti-inflammatory effects of RGD-functionalized silk fibroin nanoparticles in trinitrobenzenesulfonic acid-induced experimental colitis in rats
Q42366229Intestinal anti-inflammatory effects of goat whey on DNBS-induced colitis in mice.
Q37194625Intestinal barrier analysis by assessment of mucins, tight junctions, and α-defensins in healthy C57BL/6J and BALB/cJ mice
Q41036794Intestinal barrier dysfunction in cirrhosis: Current concepts in pathophysiology and clinical implications
Q38009940Intestinal barrier function in health and gastrointestinal disease
Q27023724Intestinal barrier in inflammatory bowel disease
Q38190874Intestinal epithelial cells: regulators of barrier function and immune homeostasis
Q34438743Intestinal inflammation and mucosal barrier function
Q24628739Intestinal microbiota in human health and disease: the impact of probiotics
Q57177121Intestinal organoids for modelling intestinal development and disease
Q90205918Intestinal permeability in the pathogenesis of liver damage: From non-alcoholic fatty liver disease to liver transplantation
Q27015884Intestinal permeability--a new target for disease prevention and therapy
Q90636719Intestine-Specific Overexpression of LDLR Enhances Cholesterol Excretion and Induces Metabolic Changes in Male Mice
Q55259683Intraperitoneal administration of the anti-IL-23 antibody prevents the establishment of intestinal nematodes in mice.
Q45906595Intravenous administration of tetramethylpyrazine reduces intestinal ischemia-reperfusion injury in rats.
Q38418016Involvement of the gut chemosensory system in the regulation of colonic anion secretion
Q92744367Is the colon mucosa affected by ten days of gastric restriction in an animal model?
Q90164425Isolation and Identification of Lactic Acid Bacteria Probiotic Culture Candidates for the Treatment of Salmonella enterica Serovar Enteritidis in Neonatal Turkey Poults
Q33721363Keratins regulate colonic epithelial cell differentiation through the Notch1 signalling pathway
Q57023971Knockout of ClC-2 reveals critical functions of adherens junctions in colonic homeostasis and tumorigenicity
Q37402440L13a-dependent translational control in macrophages limits the pathogenesis of colitis
Q50048362Lactic Acid Bacteria may Impact Intestinal Barrier Function by Modulating Goblet Cells
Q24629732Lactobacillus rhamnosus GG culture supernatant ameliorates acute alcohol-induced intestinal permeability and liver injury
Q38007176Lactoferrin: an alternative view of its role in human biological fluids
Q90880850Laminarin-rich extract improves growth performance, small intestinal morphology, gene expression of nutrient transporters and the large intestinal microbial composition of piglets during the critical post-weaning period
Q61443132Lineage tracing of Notch1-expressing cells in intestinal tumours reveals a distinct population of cancer stem cells
Q36345918Loss of NHE8 expression impairs intestinal mucosal integrity
Q28586189Loss of TMF/ARA160 protein renders colonic mucus refractory to bacterial colonization and diminishes intestinal susceptibility to acute colitis
Q89422212Low Levels of Chito-Oligosaccharides Are Not Effective in Reducing Deoxynivalenol Toxicity in Swine Jejunal Explants
Q57155903Low expression of MUC2 is associated with longer disease-free survival in patients with colorectal carcinoma
Q92063589Low-dose interleukin-2 alleviates dextran sodium sulfate-induced colitis in mice by recovering intestinal integrity and inhibiting AKT-dependent pathways
Q37604087MUC2 expression is an adverse prognostic factor in superficial gastroesophageal adenocarcinomas
Q34195190MUC2 polymorphisms are associated with endometriosis development and infertility: a case-control study
Q59798724Mast Cells Respond to Candida albicans Infections and Modulate Macrophages Phagocytosis of the Fungus
Q40361329Maternal short-chain fructo-oligosaccharide supplementation increases intestinal cytokine secretion, goblet cell number, butyrate concentration and Lawsonia intracellularis humoral vaccine response in weaned pigs
Q47133700Matrix metalloproteinase MMP9 maintains epithelial barrier function and preserves mucosal lining in colitis associated cancer
Q35190707Maturation of the enteric mucosal innate immune system during the postnatal period
Q38869770Mechanisms and consequences of intestinal dysbiosis.
Q58774497Mechanisms regulating intestinal barrier integrity and its pathological implications
Q34405164Membrane-bound mucins and mucin terminal glycans expression in idiopathic or Helicobacter pylori, NSAID associated peptic ulcers
Q39339639Mend Your Fences: The Epithelial Barrier and its Relationship With Mucosal Immunity in Inflammatory Bowel Disease
Q30649847Metabolomics approaches for characterizing metabolic interactions between host and its commensal microbes.
Q28555167Metformin Improves Ileal Epithelial Barrier Function in Interleukin-10 Deficient Mice
Q35803149MicroRNA-146a constrains multiple parameters of intestinal immunity and increases susceptibility to DSS colitis
Q57193137Microbial interactions with the intestinal epithelium and beyond: Focusing on immune cell maturation and homeostasis
Q34714938Microbial sensing by goblet cells controls immune surveillance of luminal antigens in the colon
Q33852108Microbiota and Probiotics in Health and HIV Infection.
Q35172851Microbiota and mucosal immunity in amphibians
Q39443027Micromanagement in the gut: microenvironmental factors govern colon mucosal biofilm structure and functionality
Q51419671Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip.
Q37424310Modulation of conjunctival goblet cell function by inflammatory cytokines
Q64097325Modulation of microbial communities and mucosal gene expression in chicken intestines after galactooligosaccharides delivery In Ovo
Q35658393Monitoring host responses to the gut microbiota
Q47351859Morphometric features and glycoconjugate pattern of rabbit intestine are affected by particle size of pelleted diets
Q36464549Morphoquantitative analysis of the Ileum of C57BL/6 mice (Mus musculus) fed with a high-fat diet
Q51146891Mouse intestinal niche cells express a distinct α1,2-fucosylated glycan recognized by a lectin from Burkholderia cenocepacia.
Q36939943Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer.
Q64093534Mucins: the Old, the New and the Promising Factors in Hepatobiliary Carcinogenesis
Q35558518Mucosal Immune Development in Early Life: Setting the Stage
Q36877117Mucosal barrier in ulcerative colitis and Crohn's disease
Q39428969Mucosal immune system of the gastrointestinal tract: maintaining balance between the good and the bad.
Q40690062Mucosal tolerance of the hookworm Ancylostoma caninum in the gut of naturally infected wild dogs
Q35577303Mucus mediated protection against acute colitis in adiponectin deficient mice.
Q33690086Multifactorial Modulation of Food-Induced Anaphylaxis
Q92973305Multiscale network analysis reveals molecular mechanisms and key regulators of the tumor microenvironment in gastric cancer
Q33907548NOD-like receptors in intestinal homeostasis and epithelial tissue repair
Q34428676NOTCH1, HIF1A and other cancer-related proteins in lung tissue from uranium miners--variation by occupational exposure and subtype of lung cancer
Q57294465NanI Sialidase Is an Important Contributor to Type F Strain F4969 Intestinal Colonization in Mice
Q36558792Natural killer cells protect against mucosal and systemic infection with the enteric pathogen Citrobacter rodentium
Q89928704Neither non-toxigenic Staphylococcus aureus nor commensal S. epidermidi activates NLRP3 inflammasomes in human conjunctival goblet cells
Q51000398Neonatal hyperoxia disrupts the intestinal barrier and impairs intestinal function in rats.
Q92328491Nutritional and Pharmacological Targeting of the Calcium-Sensing Receptor Influences Chemically Induced Colitis in Mice
Q89186436Obesity, independent of diet, drives lasting effects on intestinal epithelial stem cell proliferation in mice
Q37057316Paraoxonase 2 modulates a proapoptotic function in LS174T cells in response to quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone
Q38275103Pathogenesis of necrotizing enterocolitis: modeling the innate immune response.
Q26824138Pathological bacterial translocation in liver cirrhosis
Q35550110Pea (Pisum sativum L.) seed albumin extracts show anti-inflammatory effect in the DSS model of mouse colitis
Q36144186Pea protein concentrate in diets for sharpsnout sea bream (Diplodus puntazzo): effects on growth and health status.
Q36790193Pharmacology and clinical potential of guanylyl cyclase C agonists in the treatment of ulcerative colitis
Q38405642Porcine epidemic diarrhea virus infection: Etiology, epidemiology, pathogenesis and immunoprophylaxis
Q33669559Postnatal development of the small intestinal mucosa drives age-dependent, regio-selective susceptibility to Escherichia coli K1 infection
Q90636691Potential of Omega-3 Polyunsaturated Fatty Acids in Managing Chemotherapy- or Radiotherapy-Related Intestinal Microbial Dysbiosis
Q48342732Potential usefulness of methyl gallate in the treatment of experimental colitis
Q63443950Precision Nutrition and the Microbiome, Part I: Current State of the Science.
Q91785576Prevention of excessive exercise-induced adverse effects in rats with Bacillus subtilis BSB3
Q40995492Preventive and therapeutic effects of Lactobacillus paracasei B21060-based synbiotic treatment on gut inflammation and barrier integrity in colitic mice
Q38731591Probing mucin interaction behavior of magnetic nanoparticles
Q42363225Probiotic Mixture Golden Bifido Prevents Neonatal Escherichia coli K1 Translocation via Enhancing Intestinal Defense
Q53224425Protective effects of β-casofensin, a bioactive peptide from bovine β-casein, against indomethacin-induced intestinal lesions in rats.
Q33628431Protein-losing pseudomembranous colitis with cap polyposis-like features
Q39154995Putative mechanisms of kiwifruit on maintenance of normal gastrointestinal function.
Q42210301Quantitative immunohistochemical assessment of IgA, IgM, IgG and antigen-specific immunoglobulin secreting plasma cells in pig small intestinal lamina propria.
Q35554780Rapid identification of goblet cells in unstained colon thin sections by means of quantum cascade laser-based infrared microspectroscopy
Q55087094Regulation of Intestinal Epithelial Cells Properties and Functions by Amino Acids.
Q58801064Retinoic Acid, Leaky Gut, and Autoimmune Diseases
Q38828436Review article: the pathogenesis of pouchitis
Q60908746Role of colonic microbiota in the pathogenesis of ulcerative colitis
Q37969586Role of gut microbiota in food tolerance and allergies.
Q37969288Role of mucus layers in gut infection and inflammation
Q35624584Role of the gastrointestinal ecosystem in the development of type 1 diabetes.
Q26798294Role of the normal gut microbiota
Q41358282Roles and regulation of the mucus barrier in the gut.
Q39331432Roles of intestinal epithelial cells in the maintenance of gut homeostasis
Q35921507Ruminococcus gnavus E1 modulates mucin expression and intestinal glycosylation
Q54978591SCF/c-KIT Signaling Increased Mucin2 Production by Maintaining Atoh1 Expression in Mucinous Colorectal Adenocarcinoma.
Q26796416Saccharomyces boulardii CNCM I-745 supports regeneration of the intestinal microbiota after diarrheic dysbiosis - a review
Q38052951Secreted and membrane-bound mucins and idiopathic peptic ulcer disease
Q33628862Self-adjuvanting C18 lipid vinil sulfone-PP2A vaccine: study of the induced immunomodulation against Trichuris muris infection
Q64226721Serum protein expression in Equine Glandular Gastric Disease (EGGD) induced by phenylbutazone
Q21090622Sex hormones selectively impact the endocervical mucosal microenvironment: implications for HIV transmission
Q35121243Shuttling of information between the mucosal and luminal environment drives intestinal homeostasis
Q41237008Small intestinal injury in mice infected with respiratory influenza A virus: evidence for virus induced gastroenteritis
Q28727626Specific expression of human intelectin-1 in malignant pleural mesothelioma and gastrointestinal goblet cells
Q46210912Spray-dried plasma promotes growth, modulates the activity of antioxidant defenses, and enhances the immune status of gilthead sea bream (Sparus aurata) fingerlings.
Q46387030Starch-enriched diet modulates the glucidic profile in the rat colonic mucosa
Q42240229Streptococcus infantarius and carcinogenesis: a new chapter in colorectal pathology
Q27701746Structural and adhesive properties of the long polar fimbriae protein LpfD from adherent-invasive Escherichia coli
Q30544011Studies of mucus in mouse stomach, small intestine, and colon. I. Gastrointestinal mucus layers have different properties depending on location as well as over the Peyer's patches
Q45740348Suppression of inflammation and tissue damage by a hookworm recombinant protein in experimental colitis
Q31076852TH17, TH22 and Treg cells are enriched in the healthy human cecum
Q90405711Targeting the gut barrier for the treatment of alcoholic liver disease
Q34462636Tear film mucins: front line defenders of the ocular surface; comparison with airway and gastrointestinal tract mucins
Q55019416The Administration of Escherichia coli Nissle 1917 Ameliorates Development of DSS-Induced Colitis in Mice.
Q57120648The Brain-Gut-Microbiome Axis
Q51049970The Effects of Direct-fed Microbial Supplementation, as an Alternative to Antibiotics, on Growth Performance, Intestinal Immune Status, and Epithelial Barrier Gene Expression in Broiler Chickens.
Q26773231The First Line of Defense: The Effects of Alcohol on Post-Burn Intestinal Barrier, Immune Cells, and Microbiome
Q39873963The Gut Microbiome in the NOD Mouse.
Q36521651The Role of Mucosal Defense in Intestinal Injury of Infants With Fetal Growth Retardation
Q36493367The anti-ulcerative colitis effects of Annona squamosa Linn. leaf aqueous extract in experimental animal model
Q58549968The challenges of oral drug delivery via nanocarriers
Q35017883The colon: from banal to brilliant
Q46333453The colonic groove of the plains viscacha (Lagostomus maximus): Histochemical evidence of an abrupt change in the glycosylation pattern of goblet cells
Q33856245The dietary polysaccharide maltodextrin promotes Salmonella survival and mucosal colonization in mice
Q40720325The effect of porcine reproductive and respiratory syndrome virus and porcine epidemic diarrhea virus challenge on growing pigs II: Intestinal integrity and function
Q28477738The extraordinarily complex but highly structured organization of intestinal mucus-gel unveiled in multicolor images
Q36738035The gastrointestinal immune system: Implications for the surgical patient.
Q34332180The gastrointestinal mucus system in health and disease
Q28384695The gut wall provides an effective barrier against nanoparticle uptake
Q37518329The immunological characteristics and probiotic function of recombinant Bacillus subtilis spore expressing Clonorchis sinensis cysteine protease
Q35003717The impact of diet and lifestyle on gut microbiota and human health
Q41196202The impact of synbiotic administration through in ovo technology on the microstructure of a broiler chicken small intestine tissue on the 1st and 42nd day of rearing.
Q38008242The interactions between endogenous bacteria, dietary components and the mucus layer of the large bowel.
Q91241929The many faces of tumor necrosis factor signaling in the intestinal epithelium
Q37264731The mucin Muc2 limits pathogen burdens and epithelial barrier dysfunction during Salmonella enterica serovar Typhimurium colitis
Q27026950The mucosal immune system of fish: the evolution of tolerating commensals while fighting pathogens
Q37120486The novel enterochromaffin marker Lmx1a regulates serotonin biosynthesis in enteroendocrine cell lineages downstream of Nkx2.2.
Q92479640The protective effect of icariin and phosphorylated icariin against LPS-induced intestinal goblet cell dysfunction
Q28478222The rat IgGFcγBP and Muc2 C-terminal domains and TFF3 in two intestinal mucus layers bind together by covalent interaction
Q37433229The role of TL1A and DR3 in autoimmune and inflammatory diseases
Q38115440The role of the immune system in governing host-microbe interactions in the intestine
Q48366071Toxoplasma gondii promotes changes in VIPergic submucosal neurons, mucosal intraepithelial lymphocytes, and goblet cells during acute infection in the ileum of rats.
Q42778188Transcriptomic Landscape of Treatment - Naïve Ulcerative Colitis
Q86557513Transmembrane mucin MUC1 overexpression and its association with CD10⁺ myeloid cells, transforming growth factor-β1 expression, and tumor budding grade in colorectal cancer
Q37327715Triterpenoid herbal saponins enhance beneficial bacteria, decrease sulfate-reducing bacteria, modulate inflammatory intestinal microenvironment and exert cancer preventive effects in ApcMin/+ mice
Q26825483Ulcerative colitis as a polymicrobial infection characterized by sustained broken mucus barrier
Q57096471Unraveling the dose-response puzzle of : A mechanistic approach
Q36780412Urinary proteome analysis of irritable bowel syndrome (IBS) symptom subgroups
Q36375028Using unfixed, frozen tissues to study natural mucin distribution
Q90196963VAMP8-mediated MUC2 mucin exocytosis from colonic goblet cells maintains innate intestinal homeostasis
Q26765110What a Dinner Party! Mechanisms and Functions of Interkingdom Signaling in Host-Pathogen Associations
Q84341369[Digestive expression (pancreatic and intestinal) of cystic fibrosis: an approach based on physiopathology]
Q36308942hnRNP I regulates neonatal immune adaptation and prevents colitis and colorectal cancer
Q37655938γδ T-cell-deficient mice show alterations in mucin expression, glycosylation, and goblet cells but maintain an intact mucus layer

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