| P50 | author | Asma Nusrat | Q77916415 |
| P2093 | author name string | Charles A Parkos | |
| | Anny-Claude Luissint | |
| P2860 | cites work | A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation | Q21136045 |
| | The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42 | Q22254751 |
| | Rho‐kinase/ROCK: A key regulator of the cytoskeleton and cell polarity | Q24298069 |
| | Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial coxsackie and adenovirus receptor and a junctional adhesion molecule-like protein on neutrophils | Q24299261 |
| | Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions | Q24299926 |
| | JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function | Q24311647 |
| | Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo | Q24318656 |
| | MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival | Q24338226 |
| | Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression | Q24536188 |
| | Lipolysis-stimulated lipoprotein receptor (LSR) is the host receptor for the binary toxin Clostridium difficile transferase (CDT) | Q24635365 |
| | Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions | Q24669667 |
| | Cingulin contains globular and coiled-coil domains and interacts with ZO-1, ZO-2, ZO-3, and myosin | Q24670442 |
| | Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions | Q24672971 |
| | Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells | Q24679401 |
| | Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin | Q24682664 |
| | Pathogen Resistance Mediated by IL-22 Signaling at the Epithelial-Microbiota Interface | Q26779745 |
| | X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motif | Q27634027 |
| | Crystal structure of human junctional adhesion molecule 1: Implications for reovirus binding | Q27640992 |
| | Crystal structure of a claudin provides insight into the architecture of tight junctions | Q27690052 |
| | Tight junctions. Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin | Q27697986 |
| | Induction of intestinal Th17 cells by segmented filamentous bacteria | Q28131638 |
| | Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry | Q28131832 |
| | Human junction adhesion molecule regulates tight junction resealing in epithelia | Q28138238 |
| | Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin | Q28139702 |
| | Etanercept for active Crohn's disease: a randomized, double-blind, placebo-controlled trial | Q28202166 |
| | Junction adhesion molecule is a receptor for reovirus | Q28203704 |
| | Multifunctional strands in tight junctions | Q28210051 |
| | Fontolizumab in moderate to severe Crohn's disease: a phase 2, randomized, double-blind, placebo-controlled, multiple-dose study | Q28253174 |
| | Non-muscle myosin II takes centre stage in cell adhesion and migration | Q28262326 |
| | Cloning and characterization of MUPP1, a novel PDZ domain protein | Q28267302 |
| | Physiology and function of the tight junction | Q28270069 |
| | Occludin is concentrated at tight junctions of mouse/rat but not human/guinea pig Sertoli cells in testes | Q28272596 |
| | The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton | Q28287040 |
| | Stem cells, self-renewal, and differentiation in the intestinal epithelium | Q28294807 |
| | Getting to the site of inflammation: the leukocyte adhesion cascade updated | Q29547271 |
| | Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators | Q29615694 |
| | Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux | Q30009590 |
| | Tricellulin forms a barrier to macromolecules in tricellular tight junctions without affecting ion permeability | Q30491701 |
| | CAR regulates epithelial cell junction stability through control of E-cadherin trafficking | Q30548627 |
| | Transmigrated neutrophils in the intestinal lumen engage ICAM-1 to regulate the epithelial barrier and neutrophil recruitment | Q30581018 |
| | Cingulin interacts with F-actin in vitro | Q33292374 |
| | A unique role for nonmuscle myosin heavy chain IIA in regulation of epithelial apical junctions | Q33292672 |
| | TNFalpha up-regulates claudin-2 expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling | Q33408865 |
| | Protein kinase C activation disrupts epithelial apical junctions via ROCK-II dependent stimulation of actomyosin contractility | Q33440901 |
| | Interactions between the host innate immune system and microbes in inflammatory bowel disease | Q33554402 |
| | Molecular basis of the core structure of tight junctions | Q33685399 |
| | Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability | Q35797634 |
| | Gut biogeography of the bacterial microbiota | Q35820919 |
| | Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions | Q35949016 |
| | Inflammation-induced desmoglein-2 ectodomain shedding compromises the mucosal barrier | Q36058429 |
| | The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells | Q36276564 |
| | Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions | Q36289162 |
| | JAM-A regulates permeability and inflammation in the intestine in vivo | Q36294373 |
| | IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis | Q36303708 |
| | Cutting Edge: IL-36 Receptor Promotes Resolution of Intestinal Damage | Q36386989 |
| | Tight junctions: molecular architecture and function | Q36400271 |
| | Mucosal IL-10 and TGF-beta play crucial roles in preventing LPS-driven, IFN-gamma-mediated epithelial damage in human colon explants | Q36439020 |
| | Protein kinase CK2 is a critical regulator of epithelial homeostasis in chronic intestinal inflammation | Q36455179 |
| | Physiological roles for ecto-5'-nucleotidase (CD73). | Q36478279 |
| | Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair | Q36497289 |
| | Compromised intestinal epithelial barrier induces adaptive immune compensation that protects from colitis | Q36588077 |
| | Nonmuscle Myosin IIA Regulates Intestinal Epithelial Barrier in vivo and Plays a Protective Role During Experimental Colitis | Q36785206 |
| | Epithelial tight junctions, gene expression and nucleo-junctional interplay | Q36799008 |
| | Adherens and tight junctions: structure, function and connections to the actin cytoskeleton | Q36940193 |
| | Desmosomes: new perspectives on a classic | Q36970223 |
| | Structural organization of the tight junctions | Q36975080 |
| | Crosstalk of tight junction components with signaling pathways | Q36976365 |
| | Structure and function of desmosomes | Q36983434 |
| | IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis. | Q37068500 |
| | Novel mechanism of cytokine-induced disruption of epithelial barriers: Janus kinase and protein kinase D-dependent downregulation of junction protein expression | Q37197950 |
| | Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. | Q37266104 |
| | Differential pathways of claudin oligomerization and integration into tight junctions | Q37402174 |
| | Neutrophil-mediated activation of epithelial protease-activated receptors-1 and -2 regulates barrier function and transepithelial migration | Q37423888 |
| | Cleavage of transmembrane junction proteins and their role in regulating epithelial homeostasis | Q37428089 |
| | AMP-activated protein kinase mediates the interferon-gamma-induced decrease in intestinal epithelial barrier function | Q37459893 |
| | Small GTPases of the Ras superfamily regulate intestinal epithelial homeostasis and barrier function via common and unique mechanisms. | Q37617010 |
| | The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis. | Q37627550 |
| | Endocytosis and recycling of tight junction proteins in inflammation | Q37654826 |
| | Phosphatase regulation of intercellular junctions | Q37728541 |
| | Adherens junction: molecular architecture and regulation | Q37748230 |
| | On the interaction of Clostridium perfringens enterotoxin with claudins | Q37954298 |
| | A review and expert opinion of the use of certolizumab for Crohn's disease | Q37984556 |
| | The role of neutrophils during intestinal inflammation | Q38001546 |
| | Dishonorable discharge: the oncogenic roles of cleaved E-cadherin fragments | Q38015669 |
| | Adherens junction assembly | Q38016764 |
| | Dynamics and regulation of epithelial adherens junctions: recent discoveries and controversies | Q38085107 |
| | Optimizing anti-TNF treatments in inflammatory bowel disease | Q38116299 |
| | Intestinal epithelial cells: regulators of barrier function and immune homeostasis | Q38190874 |
| | JAM-related proteins in mucosal homeostasis and inflammation | Q38199343 |
| | Interleukin-6 (IL-6) regulates claudin-2 expression and tight junction permeability in intestinal epithelium | Q38417912 |
| | Claudin switching: Physiological plasticity of the Tight Junction | Q38468882 |
| | Neutrophil-Epithelial Interactions: A Double-Edged Sword | Q38809434 |
| | Neutrophil-derived JAML inhibits repair of intestinal epithelial injury during acute inflammation. | Q39016237 |
| | STAT3 activation in Th17 and Th22 cells controls IL-22-mediated epithelial host defense during infectious colitis | Q39135086 |
| | Cytokines in inflammatory bowel disease | Q39206254 |
| | Claudin-2 regulates colorectal inflammation via myosin light chain kinase-dependent signaling. | Q39212748 |
| | Shigella targets epithelial tricellular junctions and uses a noncanonical clathrin-dependent endocytic pathway to spread between cells | Q39361599 |
| | The density of small tight junction pores varies among cell types and is increased by expression of claudin-2. | Q40024709 |
| | Resolvin E1 promotes mucosal surface clearance of neutrophils: a new paradigm for inflammatory resolution | Q40134026 |
| | Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases. | Q40186985 |
| | Interferon-gamma induces internalization of epithelial tight junction proteins via a macropinocytosis-like process | Q40415725 |
| | Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation. | Q40472720 |
| | Neutrophils migrate across intestinal epithelium using beta2 integrin (CD11b/CD18)-independent mechanisms | Q40566570 |
| | IFN-γ-mediated induction of an apical IL-10 receptor on polarized intestinal epithelia. | Q33702103 |
| | Multiple protein interactions involving proposed extracellular loop domains of the tight junction protein occludin | Q33734527 |
| | Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity | Q33782512 |
| | Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis | Q33785525 |
| | Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo | Q33788423 |
| | Protection of epithelial barrier function by the Crohn's disease associated gene protein tyrosine phosphatase n2 | Q33793839 |
| | Xenopus laevis occludin. Identification of in vitro phosphorylation sites by protein kinase CK2 and association with cingulin. | Q33874518 |
| | p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice | Q33882907 |
| | 5'-adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers | Q33900552 |
| | Multiple phenotypes in adult mice following inactivation of the Coxsackievirus and Adenovirus Receptor (Car) gene | Q33933004 |
| | Molecular organization of tricellular tight junctions | Q33983087 |
| | CAR: a virus receptor within the tight junction | Q33986342 |
| | Cytoskeletal regulation of epithelial barrier function during inflammation | Q34033538 |
| | Role of the gut microbiota in immunity and inflammatory disease | Q34036490 |
| | Occludin is required for cytokine-induced regulation of tight junction barriers | Q34043395 |
| | Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane | Q34049874 |
| | A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier | Q34064091 |
| | Intestinal goblet cells and mucins in health and disease: recent insights and progress | Q34102377 |
| | Nectin and afadin: novel organizers of intercellular junctions. | Q34161446 |
| | Proinflammatory cytokine-induced tight junction remodeling through dynamic self-assembly of claudins | Q34166824 |
| | Helicobacter pylori activates myosin light-chain kinase to disrupt claudin-4 and claudin-5 and increase epithelial permeability | Q34194569 |
| | Clostridium perfringens enterotoxin damages the human intestine in vitro | Q34194740 |
| | Neutrophil migration across a cultured intestinal epithelium. Dependence on a CD11b/CD18-mediated event and enhanced efficiency in physiological direction | Q34209118 |
| | IL-1beta-induced increase in intestinal epithelial tight junction permeability is mediated by MEKK-1 activation of canonical NF-kappaB pathway | Q34254423 |
| | Homeostatic IL-23 receptor signaling limits Th17 response through IL-22-mediated containment of commensal microbiota. | Q34281233 |
| | Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin | Q34290465 |
| | The Role of cis Dimerization of Signal Regulatory Protein α (SIRPα) in Binding to CD47 | Q34351985 |
| | Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complex | Q34359173 |
| | Proresolving lipid mediators and mechanisms in the resolution of acute inflammation | Q34411426 |
| | Surface area of the digestive tract - revisited | Q34413322 |
| | Targeted colonic claudin-2 expression renders resistance to epithelial injury, induces immune suppression, and protects from colitis. | Q34457032 |
| | Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trial | Q34574245 |
| | Intestinal epithelial cells as a source of inflammatory cytokines and chemokines | Q34618333 |
| | Claudins and the modulation of tight junction permeability | Q34650517 |
| | Clustering of increased small intestinal permeability in families with Crohn's disease. | Q34742820 |
| | Complex phenotype of mice lacking occludin, a component of tight junction strands. | Q34781594 |
| | Endocytosis of Epithelial Apical Junctional Proteins by a Clathrin-mediated Pathway into a Unique Storage Compartment | Q34786013 |
| | The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system | Q34798439 |
| | Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function | Q34918139 |
| | Occludin regulates macromolecule flux across the intestinal epithelial tight junction barrier | Q35057031 |
| | α-Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism. | Q35178282 |
| | Claudin-2 as a mediator of leaky gut barrier during intestinal inflammation | Q35212830 |
| | Human neutrophil formyl peptide receptor phosphorylation and the mucosal inflammatory response | Q35227742 |
| | Neutrophil transmigration triggers repair of the lung epithelium via beta-catenin signaling. | Q35229097 |
| | Interleukin-22: immunobiology and pathology | Q35530956 |
| | Junctional adhesion molecules (JAMs): more molecules with dual functions? | Q35600846 |
| | Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function. | Q35611410 |
| | Inflammation and disruption of the mucosal architecture in claudin-7-deficient mice | Q35705366 |
| | Neutrophil transmigration in inflammatory bowel disease is associated with differential expression of epithelial intercellular junction proteins | Q35747165 |
| | Host-microbial interactions and regulation of intestinal epithelial barrier function: From physiology to pathology. | Q35772165 |
| | Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms | Q40614064 |
| | Isolation and functional characterization of the actin binding region in the tight junction protein ZO-1. | Q40700804 |
| | Neutrophil-mediated epithelial injury during transmigration: role of elastase | Q40784412 |
| | Functional modeling of tight junctions in intestinal cell monolayers using polyethylene glycol oligomers | Q40794057 |
| | Modulation of barrier function during Fas-mediated apoptosis in human intestinal epithelial cells | Q40838088 |
| | Expression from the human occludin promoter is affected by tumor necrosis factor alpha and interferon gamma. | Q40880588 |
| | Localization of membrane-associated guanylate kinase (MAGI)-1/BAI-associated protein (BAP) 1 at tight junctions of epithelial cells | Q40908844 |
| | Interferon-gamma decreases barrier function in T84 cells by reducing ZO-1 levels and disrupting apical actin | Q40954070 |
| | Epithelial ion transport and barrier abnormalities evoked by superantigen-activated immune cells are inhibited by interleukin-10 but not interleukin-4. | Q41004283 |
| | Neutrophil-Epithelial Cell Interactions in the Intestine | Q41705152 |
| | Role of tight junctions in establishing and maintaining cell polarity. | Q41748269 |
| | Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function. | Q42436011 |
| | Claudins regulate the intestinal barrier in response to immune mediators | Q42488651 |
| | Ustekinumab induction and maintenance therapy in refractory Crohn's disease | Q42514321 |
| | A peptide-based target screen implicates the protein kinase CK2 in the global regulation of caspase signaling | Q42600377 |
| | IL-36R signalling activates intestinal epithelial cells and fibroblasts and promotes mucosal healing in vivo | Q42772715 |
| | The role of CD47 in neutrophil transmigration. Increased rate of migration correlates with increased cell surface expression of CD47. | Q43691944 |
| | Intestinal permeability in patients with Crohn's disease and their healthy relatives | Q43863082 |
| | CD11b/CD18-dependent interactions of neutrophils with intestinal epithelium are mediated by fucosylated proteoglycans | Q44187679 |
| | Loss of claudins 2 and 15 from mice causes defects in paracellular Na+ flow and nutrient transport in gut and leads to death from malnutrition | Q44212540 |
| | In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization | Q44225643 |
| | Cytokine/chemokine transcript profiles reflect mucosal inflammation in Crohn?s disease | Q44647507 |
| | Intestinal absorptive cell tight junctions are linked to cytoskeleton | Q46186998 |
| | Epithelial transport and barrier function in occludin-deficient mice | Q46447620 |
| | Specific modulation of airway epithelial tight junctions by apical application of an occludin peptide | Q47691159 |
| | Role of cadherin internalization in hydrogen peroxide-mediated endothelial permeability | Q48024935 |
| | A new role for reticulon-4B/NOGO-B in the intestinal epithelial barrier function and inflammatory bowel disease. | Q50447240 |
| | Intestinal deletion of Claudin-7 enhances paracellular organic solute flux and initiates colonic inflammation in mice. | Q50600432 |
| | Neutrophil migration across model intestinal epithelia: monolayer disruption and subsequent events in epithelial repair. | Q52527760 |
| | The disruption of adherens junctions is associated with a decrease of E-cadherin phosphorylation by protein kinase CK2. | Q52539454 |
| | Par-3 modulates intestinal epithelial barrier function through regulating intracellular trafficking of occludin and myosin light chain phosphorylation. | Q52955402 |
| | Effects of T cell-induced colonic inflammation on epithelial barrier function. | Q53341945 |
| | Infliximab, azathioprine, or combination therapy for Crohn's disease | Q56988763 |
| | Interleukin 10 prevents cytokine-induced disruption of T84 monolayer barrier integrity and limits chloride secretion | Q59120768 |
| | Phosphorylation of the 20,000-dalton light chain of smooth muscle myosin by the calcium-activated, phospholipid-dependent protein kinase. Phosphorylation sites and effects of phosphorylation | Q70183097 |
| | Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease | Q70489716 |
| | Inflammatory bowel disease is associated with changes of enterocytic junctions | Q74025969 |
| | Megaintestine in claudin-15-deficient mice | Q80612306 |
| | Loss of Claudin-15, but Not Claudin-2, Causes Na+ Deficiency and Glucose Malabsorption in Mouse Small Intestine | Q84779796 |
| | Ulcerative colitis | Q84851901 |
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | inflammation | Q101991 |
| P304 | page(s) | 616-632 | |
| P577 | publication date | 2016-07-16 | |
| P1433 | published in | Gastroenterology | Q4039279 |
| P1476 | title | Inflammation and the Intestinal Barrier: Leukocyte-Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair | |
| P478 | volume | 151 | |