scholarly article | Q13442814 |
P50 | author | W Vallen Graham | Q73205624 |
P2093 | author name string | Jerrold R Turner | |
Yingmin Wang | |||
Fengjun Wang | |||
Brad T Schwarz | |||
Edwina D Witkowski | |||
P2860 | cites work | Sulphasalazine inhibits macrophage activation: inhibitory effects on inducible nitric oxide synthase expression, interleukin-12 production and major histocompatibility complex II expression | Q28347747 |
Permeability of human HT-29/B6 colonic epithelium as a function of apoptosis | Q28348796 | ||
Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B | Q28379350 | ||
IFN-gamma modulation of epithelial barrier function. Time course, reversibility, and site of cytokine binding | Q30467607 | ||
Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease | Q34145454 | ||
Effect of cytokines on the epithelial function of the human colon carcinoma cell line HT29 cl 19A | Q34376559 | ||
Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers | Q34567309 | ||
Loosening tight junctions. Lessons from the intestine | Q34569725 | ||
Maintenance of the macromolecular barrier at cell extrusion sites in intestinal epithelium: physiological rearrangement of tight junctions | Q34786600 | ||
T cell activation causes diarrhea by increasing intestinal permeability and inhibiting epithelial Na+/K+-ATPase. | Q34816745 | ||
A porous defense: the leaky epithelial barrier in intestinal disease. | Q35651435 | ||
Salicylates and sulfasalazine, but not glucocorticoids, inhibit leukocyte accumulation by an adenosine-dependent mechanism that is independent of inhibition of prostaglandin synthesis and p105 of NFkappaB. | Q37208648 | ||
Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms | Q40614064 | ||
Tumor necrosis factor regulates intestinal epithelial cell migration by receptor-dependent mechanisms | Q40685684 | ||
Increased intestinal permeability precedes the onset of Crohn's disease in a subject with familial risk | Q40735088 | ||
Inhibition of Na+,K+-ATPase by interferon gamma down-regulates intestinal epithelial transport and barrier function | Q40811303 | ||
Modulation of barrier function during Fas-mediated apoptosis in human intestinal epithelial cells | Q40838088 | ||
Suppression of NF-kappaB activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta | Q40845763 | ||
Expression from the human occludin promoter is affected by tumor necrosis factor alpha and interferon gamma. | Q40880588 | ||
Tight junctions are membrane microdomains | Q40886204 | ||
Interferon-gamma decreases barrier function in T84 cells by reducing ZO-1 levels and disrupting apical actin | Q40954070 | ||
Tumor necrosis factor-alpha (TNFalpha) regulates the epithelial barrier in the human intestinal cell line HT-29/B6. | Q40990210 | ||
Enteropathogenic Escherichia coli-induced myosin light chain phosphorylation alters intestinal epithelial permeability | Q41077484 | ||
Expression of the catalytic domain of myosin light chain kinase increases paracellular permeability | Q41151632 | ||
Assessment of inflammatory events in epithelial permeability: a rapid screening method using fluorescein dextrans | Q41387016 | ||
Modulation of tumor necrosis factor-induced increase in renal (LLC-PK1) transepithelial permeability | Q41597813 | ||
CD45RO expression on circulating CD19+ B cells in Crohn's disease correlates with intestinal permeability | Q41663928 | ||
Effect of tumor necrosis factor on epithelial tight junctions and transepithelial permeability | Q41738669 | ||
Effects of sulfasalazine and a sulfasalazine analogue on the formation of lipoxygenase and cyclooxygenase products | Q42190722 | ||
Tumour Necrosis factor-α induces morphological and functional alterations of intestinal HT29 cl.19A cell monolayers | Q42479137 | ||
Long-term effects of tumor necrosis factor on LLC-PK1 transepithelial resistance | Q42503264 | ||
Stress-induced disruption of colonic epithelial barrier: role of interferon-gamma and myosin light chain kinase in mice | Q42797638 | ||
Transepithelial resistance can be regulated by the intestinal brush-border Na(+)/H(+) exchanger NHE3. | Q43509902 | ||
Efficacy of use of colonoscopy in dextran sulfate sodium induced ulcerative colitis in rats: the evaluation of the effects of antioxidant by colonoscopy | Q43679522 | ||
Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the x(c)- cystine transporter: a new action for an old drug | Q43756729 | ||
Regulation of human jejunal transmucosal resistance and MLC phosphorylation by Na(+)-glucose cotransport | Q43797549 | ||
An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin- and myosin-dependent mechanism | Q43812071 | ||
Bryostatin-1 attenuates TNF-induced epithelial barrier dysfunction: role of novel PKC isozymes | Q44265345 | ||
TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation | Q44758263 | ||
Autocrine regulation of epithelial permeability by hypoxia: role for polarized release of tumor necrosis factor alpha. | Q51525902 | ||
A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease. | Q53965794 | ||
PKC-dependent regulation of transepithelial resistance: roles of MLC and MLC kinase. | Q54079243 | ||
Activation of NF-kappaB is necessary for the restoration of the barrier function of an epithelium undergoing TNF-alpha-induced apoptosis. | Q54102357 | ||
The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion | Q63407202 | ||
INFLIXIMAB DOWNREGULATES INTERFERON-γ PRODUCTION IN ACTIVATED GUT T-LYMPHOCYTES FROM PATIENTS WITH CROHN'S DISEASE | Q63727345 | ||
Tumor necrosis factor inhibitor ameliorates murine intestinal graft-versus-host disease | Q64381640 | ||
Intestinal permeability and the prediction of relapse in Crohn's disease | Q72220492 | ||
Antioxidant properties of aminosalicylates | Q72377087 | ||
Effect of FR167653 on small bowel ischemia-reperfusion injury in dogs | Q73208385 | ||
Noninvasive in vivo analysis of human small intestinal paracellular absorption: regulation by Na+-glucose cotransport | Q73533349 | ||
Gut ischemia and mesenteric synthesis of inflammatory cytokines after hemorrhagic or endotoxic shock | Q73644807 | ||
Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation | Q73847660 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 409-419 | |
P577 | publication date | 2005-02-01 | |
P1433 | published in | The American Journal of Pathology | Q4744259 |
P1476 | title | Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression | |
P478 | volume | 166 |
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Q36982054 | Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation |
Q39212748 | Claudin-2 regulates colorectal inflammation via myosin light chain kinase-dependent signaling. |
Q38809387 | Clinical importance of nonsteroidal anti-inflammatory drug enteropathy: the relevance of tumor necrosis factor as a promising target. |
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Q26861369 | Conceptual barriers to understanding physical barriers |
Q89578153 | Contributions of Myosin Light Chain Kinase to Regulation of Epithelial Paracellular Permeability and Mucosal Homeostasis |
Q35052412 | Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo |
Q36704497 | Coupling between apical and paracellular transport processes |
Q28079482 | Crosstalk between Inflammation and ROCK/MLCK Signaling Pathways in Gastrointestinal Disorders with Intestinal Hyperpermeability |
Q34555811 | Crystallization and preliminary X-ray analysis of the human long myosin light-chain kinase 1-specific domain IgCAM3. |
Q101567971 | Culture of Intestinal Epithelial Cell Monolayers and Their Use in Multiplex Macromolecular Permeability Assays for In Vitro Analysis of Tight Junction Size Selectivity |
Q38666232 | Curcumin protects against the intestinal ischemia-reperfusion injury: involvement of the tight junction protein ZO-1 and TNF-α related mechanism |
Q37308566 | Cytokine regulation of tight junctions |
Q41418721 | DT-13 Ameliorates TNF-α-Induced Vascular Endothelial Hyperpermeability via Non-Muscle Myosin IIA and the Src/PI3K/Akt Signaling Pathway |
Q38834628 | Dendritic cells expressing immunoreceptor CD300f are critical for controlling chronic gut inflammation |
Q89861763 | Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD |
Q40495815 | Development of an in vitro co-culture model to mimic the human intestine in healthy and diseased state |
Q91725417 | Dietary Chitin Particles Called Mimetic Fungi Ameliorate Colitis in Toll-Like Receptor 2/CD14- and Sex-Dependent Manners |
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Q39866527 | Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression in LETO and OLETF rats |
Q53539472 | Dietary intervention with serum-derived bovine immunoglobulins protects barrier function in a mouse model of colitis. |
Q54346274 | Differential effects of nutritional and non-nutritional therapies on intestinal barrier function in an in vitro model. |
Q42199563 | Differential partial activation phenotype and production of tumour necrosis factor-α by conventional dendritic cells in response to lipopolysaccharide in HIV+ viraemic subjects and HIV+ controllers |
Q40186985 | Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases. |
Q44001914 | Does endotoxaemia contribute to osteoarthritis in obese patients? |
Q47806206 | Dynamic modeling of the tight junction pore pathway |
Q43121604 | Dynamic properties of the tight junction barrier |
Q46765488 | Dynamics of enterocyte tight junctions: effect of experimental colitis and two different anti-TNF strategies |
Q27324323 | Early mucosal sensing of SIV infection by paneth cells induces IL-1β production and initiates gut epithelial disruption |
Q46304503 | Effect of polyunsaturated fatty acids on tight junctions in a model of the human intestinal epithelium under normal and inflammatory conditions |
Q43494464 | Effects of berberine on rat jejunal motility |
Q38080687 | Effects of enteral nutrition on Crohn's disease: clues to the impact of diet on disease pathogenesis |
Q57279542 | Enhanced Gastrointestinal Passive Paracellular Permeability Contributes to the Obesity-associated Hyperoxaluria |
Q50092863 | Enteral Nutrition in the Management of Crohn's Disease: Reviewing Mechanisms of Actions and Highlighting Potential Venues for Enhancing the Efficacy |
Q39139171 | Enteric Pathogens and Their Toxin-Induced Disruption of the Intestinal Barrier through Alteration of Tight Junctions in Chickens. |
Q35836695 | Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation |
Q53845870 | Enteropathogenic E. coli disrupts tight junction barrier function and structure in vivo. |
Q33899677 | Enteropathogenic Escherichia coli inhibits type I interferon- and RNase L-mediated host defense to disrupt intestinal epithelial cell barrier function |
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Q37080684 | Fetal cholinergic anti-inflammatory pathway and necrotizing enterocolitis: the brain-gut connection begins in utero |
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Q39877230 | GEF-H1 mediates tumor necrosis factor-alpha-induced Rho activation and myosin phosphorylation: role in the regulation of tubular paracellular permeability |
Q34520959 | Gastrointestinal mucosal barrier function and diseases. |
Q35847556 | Gene expression profiling in non-human primate jejunum, ileum and colon after total-body irradiation: a comparative study of segment-specific molecular and cellular responses |
Q45743243 | Glucocorticoids regulate barrier function and claudin expression in intestinal epithelial cells via MKP-1. |
Q37559869 | Gluten-induced symptoms in diarrhea-predominant irritable bowel syndrome are associated with increased myosin light chain kinase activity and claudin-15 expression |
Q64229900 | Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability |
Q37808740 | Gut permeability and food allergies |
Q39102508 | Gut permeability and mucosal inflammation: bad, good or context dependent. |
Q42207253 | HIV replication in conjunction with granzyme B production by CCR5+ memory CD4 T cells: Implications for bystander cell and tissue pathologies. |
Q30665173 | Hepatic Injury in Nonalcoholic Steatohepatitis Contributes to Altered Intestinal Permeability |
Q36618950 | Higher expression of phosphorylated myosin regulatory light chain in the common bile duct in pancreaticobiliary maljunction accompanied by bile duct dilatation in children: a post-mortem observational study |
Q36363577 | How stress induces intestinal hypersensitivity |
Q39277299 | Hypoxia Inducible Factor (HIF) Hydroxylases as Regulators of Intestinal Epithelial Barrier Function |
Q40270359 | IFN-gamma and TNF-alpha regulate human NHE3 gene expression by modulating the Sp family transcription factors in human intestinal epithelial cell line C2BBe1. |
Q35215366 | IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction |
Q37047096 | IL-1beta causes an increase in intestinal epithelial tight junction permeability |
Q34254423 | IL-1beta-induced increase in intestinal epithelial tight junction permeability is mediated by MEKK-1 activation of canonical NF-kappaB pathway |
Q64259788 | Identification of Serum Biomarkers for Intestinal Integrity in a Broiler Chicken Malabsorption Model |
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Q36522913 | In Vivo and In Vitro Antinociceptive Effect of Fagopyrum cymosum (Trev.) Meisn Extracts: A Possible Action by Recovering Intestinal Barrier Dysfunction |
Q38902578 | Inflammation and the Intestinal Barrier: Leukocyte-Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair |
Q42288030 | Inflammatory bowel disease therapies and gut function in a colitis mouse model. |
Q35761217 | Inflammatory bowel disease: is it really just another break in the wall? |
Q46592696 | Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells. |
Q36309506 | Inhibition of long myosin light-chain kinase activation alleviates intestinal damage after binge ethanol exposure and burn injury |
Q37045757 | Innate and adaptive mechanisms to control [corrected] pathological intestinal inflammation |
Q37578039 | Intercellular adhesion molecule 1: recent findings and new concepts involved in mammalian spermatogenesis |
Q37594928 | Interferon-Alpha Promotes Th1 Response and Epithelial Apoptosis via Inflammasome Activation in Human Intestinal Mucosa |
Q33808592 | Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways |
Q39592093 | Interferon-γ-induced increases in intestinal epithelial macromolecular permeability requires the Src kinase Fyn. |
Q39853564 | Interleukin-1β Mediates β-Catenin-Driven Downregulation of Claudin-3 and Barrier Dysfunction in Caco2 Cells |
Q38417912 | Interleukin-6 (IL-6) regulates claudin-2 expression and tight junction permeability in intestinal epithelium |
Q89886066 | Intestinal Barrier Dysfunction, LPS Translocation, and Disease Development |
Q92356819 | Intestinal barrier dysfunction in severe burn injury |
Q38584691 | Intestinal epithelial barrier function and tight junction proteins with heat and exercise |
Q58556455 | Intestinal immune dysregulation driven by dysbiosis promotes barrier disruption and bacterial translocation in rats with cirrhosis |
Q35953647 | Intestinal macrophages arising from CCR2(+) monocytes control pathogen infection by activating innate lymphoid cells. |
Q29618086 | Intestinal mucosal barrier function in health and disease |
Q26859272 | Intestinal permeability regulation by tight junction: implication on inflammatory bowel diseases |
Q92767987 | Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis |
Q38117175 | Investigational cytokine-targeted therapies for ulcerative colitis. |
Q39562918 | Involvement of HIF-1α in MLCK-dependent endothelial barrier dysfunction in hypoxia |
Q37591476 | Irinotecan disrupts tight junction proteins within the gut : implications for chemotherapy-induced gut toxicity. |
Q37914788 | Is metabolic stress a common denominator in inflammatory bowel disease? |
Q38199343 | JAM-related proteins in mucosal homeostasis and inflammation |
Q36854925 | JunD represses transcription and translation of the tight junction protein zona occludens-1 modulating intestinal epithelial barrier function |
Q37259782 | LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms. |
Q36071733 | Lipid rafts regulate PCB153-induced disruption of occludin and brain endothelial barrier function through protein phosphatase 2A and matrix metalloproteinase-2 |
Q28568715 | Lipopolysaccharide disrupts tight junctions in cholangiocyte monolayers by a c-Src-, TLR4-, and LBP-dependent mechanism |
Q33816018 | Loss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrier |
Q47413203 | Lysophosphatidic Acid Receptor 1 Is Important for Intestinal Epithelial Barrier Function and Susceptibility to Colitis |
Q47313771 | MARCKS-related protein regulates cytoskeletal organization at cell-cell and cell-substrate contacts in epithelial cells. |
Q38301696 | MMPs contribute to TNF-alpha-induced alteration of the blood-cerebrospinal fluid barrier in vitro |
Q24317362 | Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability |
Q37047106 | Mechanism of cytokine modulation of epithelial tight junction barrier |
Q37047083 | Mechanism of glucocorticoid regulation of the intestinal tight junction barrier |
Q37629444 | Mechanisms and functional implications of intestinal barrier defects |
Q37594944 | Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli. |
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Q35569905 | Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application |
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Q38293774 | Mucosal healing in the era of biologic agents in treatment of inflammatory bowel disease |
Q38810529 | Mucosal pathobiology and molecular signature of epithelial barrier dysfunction in the small intestine in irritable bowel syndrome. |
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Q41982611 | Murine guanylate cyclase C regulates colonic injury and inflammation |
Q52647636 | Mycophenolic acid mediated disruption of the intestinal epithelial tight junctions. |
Q35092790 | Myosin light chain kinase expression induced via tumor necrosis factor receptor 2 signaling in the epithelial cells regulates the development of colitis-associated carcinogenesis |
Q46830240 | Myosin light chain kinase inhibition: correction of increased intestinal epithelial permeability in vitro. |
Q43474062 | Myosin light chain kinase inhibitor inhibits dextran sulfate sodium-induced colitis in mice |
Q35085249 | Myosin light chain kinase is involved in lipopolysaccharide-induced disruption of colonic epithelial barrier and bacterial translocation in rats. |
Q31057409 | Myosin light chain kinase mediates intestinal barrier disruption following burn injury |
Q38739653 | Myosin light chain kinase mediates intestinal barrier dysfunction via occludin endocytosis during anoxia/reoxygenation injury. |
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Q42082089 | No static at all. |
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Q99593443 | Non-lethal Plasmodium yoelii infection drives complex patterns of Th2-type host immunity and mast cell-dependent bacteremia |
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Q37197950 | Novel mechanism of cytokine-induced disruption of epithelial barriers: Janus kinase and protein kinase D-dependent downregulation of junction protein expression |
Q47221249 | Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development |
Q30009590 | Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux |
Q34918139 | Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function |
Q36323908 | Olive oil bioactives protect pigs against experimentally-induced chronic inflammation independently of alterations in gut microbiota |
Q26738728 | Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues |
Q51614351 | Oral administration of Parabacteroides distasonis antigens attenuates experimental murine colitis through modulation of immunity and microbiota composition. |
Q55245208 | Oral treatment with plecanatide or dolcanatide attenuates visceral hypersensitivity via activation of guanylate cyclase-C in rat models. |
Q64058580 | Orexin-A Prevents Lipopolysaccharide-Induced Neuroinflammation at the Level of the Intestinal Barrier |
Q85948686 | Osteoprotegerin exerts its pro-inflammatory effects through nuclear factor-κB activation |
Q28507355 | Overexpression of Ste20-related proline/alanine-rich kinase exacerbates experimental colitis in mice |
Q35235187 | Oxymatrine improves intestinal epithelial barrier function involving NF-κB-mediated signaling pathway in CCl4-induced cirrhotic rats |
Q42471534 | Paracellular permeability is increased by basal lipopolysaccharide in a primary culture of colonic epithelial cells; an effect prevented by an activator of Toll-like receptor-2. |
Q35689533 | Pathogenic potential of Campylobacter ureolyticus |
Q36943034 | Physiological, pathological, and therapeutic implications of zonulin-mediated intestinal barrier modulation: living life on the edge of the wall |
Q36996000 | Plasma and mucosal HIV viral loads are associated with genital tract inflammation in HIV-infected women |
Q38211365 | Pleiotropic functions of TNF-α in the regulation of the intestinal epithelial response to inflammation |
Q39578562 | Pregnane X Receptor Activation Attenuates Inflammation-Associated Intestinal Epithelial Barrier Dysfunction by Inhibiting Cytokine-Induced Myosin Light-Chain Kinase Expression and c-Jun N-Terminal Kinase 1/2 Activation |
Q89685652 | Presence of Inflammatory Group I and III Innate Lymphoid Cells in the Colon of SIV-infected Rhesus Macaques |
Q33309955 | Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrity |
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