IL-1beta-induced increase in intestinal epithelial tight junction permeability is mediated by MEKK-1 activation of canonical NF-kappaB pathway

scientific article

IL-1beta-induced increase in intestinal epithelial tight junction permeability is mediated by MEKK-1 activation of canonical NF-kappaB pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2353/AJPATH.2010.100371
P932PMC publication ID2966790
P698PubMed publication ID21048223
P5875ResearchGate publication ID47676016

P2093author name stringDongmei Ye
Rana Al-Sadi
Thomas Y Ma
Hamid M Said
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Biologic basis for interleukin-1 in diseaseQ29619853
Interleukin-1 and interleukin-1 receptor antagonist in inflammatory bowel diseaseQ30469576
Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivoQ34014510
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Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayersQ34567309
Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivoQ35052412
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Neonatal maternal deprivation triggers long term alterations in colonic epithelial barrier and mucosal immunity in rats.Q35596401
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MAP kinase kinase kinases and innate immunityQ36342970
Control of canonical NF-kappaB activation through the NIK-IKK complex pathwayQ36491362
IL-1beta causes an increase in intestinal epithelial tight junction permeabilityQ37047096
Mechanism of cytokine modulation of epithelial tight junction barrierQ37047106
MAPKs and their relevance to arthritis and inflammationQ37054686
Cytokine regulation of tight junctionsQ37308566
Crohn's disease--a permeability disorder of the tight junction?Q39558113
Inhibition of MafA transcriptional activity and human insulin gene transcription by interleukin-1beta and mitogen-activated protein kinase kinase kinase in pancreatic islet beta cellsQ40116847
Interferon-gamma induces internalization of epithelial tight junction proteins via a macropinocytosis-like processQ40415725
Thioredoxin inhibits tumor necrosis factor- or interleukin-1-induced NF-kappaB activation at a level upstream of NF-kappaB-inducing kinaseQ40822768
Requirement of the MAP kinase cascade for cell cycle progression and differentiation of human intestinal cellsQ40929368
Tumor necrosis factor-alpha increases sodium and chloride conductance across the tight junction of CACO-2 BBE, a human intestinal epithelial cell line.Q41061126
Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouseQ41122462
IL1B gene polymorphisms influence the course and severity of inflammatory bowel disease.Q41674827
Stress-induced disruption of colonic epithelial barrier: role of interferon-gamma and myosin light chain kinase in miceQ42797638
Intestinal Na+-K+-ATPase activity and molecular events downstream of interferon-gamma receptor stimulationQ43262266
Impact of different therapeutic regimens on the outcome of patients with Crohn's disease of the upper gastrointestinal tractQ43624355
Recombinant interleukin-1 receptor antagonist blocks the proinflammatory activity of endogenous interleukin-1 in rabbit immune colitisQ44121388
The mechanisms of prednisone inhibition of inflammation in Crohn's disease involve changes in intestinal permeability, mucosal TNFalpha production and nuclear factor kappa B expressionQ44535156
TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activationQ44758263
Mechanism of TNF-{alpha} modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expressionQ45258065
Cytochalasin B modulation of Caco-2 tight junction barrier: role of myosin light chain kinaseQ46044996
Two pathways to NF-kappaB.Q46113107
Molecular mechanism of tumor necrosis factor-alpha modulation of intestinal epithelial tight junction barrierQ46941133
IL-1beta, an immediate early protein secreted by activated microglia, induces iNOS/NO in C6 astrocytoma cells through p38 MAPK and NF-kappaB pathwaysQ48457874
IL-1 receptor antagonist (IL-1Ra) gene polymorphism in patients with inflammatory bowel disease in India.Q54648083
Clostridium difficile toxin B disrupts the barrier function of T84 monolayersQ67732507
Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factorQ69656337
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
P304page(s)2310-2322
P577publication date2010-11-01
P1433published inThe American Journal of PathologyQ4744259
P1476titleIL-1beta-induced increase in intestinal epithelial tight junction permeability is mediated by MEKK-1 activation of canonical NF-kappaB pathway
P478volume177

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