scholarly article | Q13442814 |
P2093 | author name string | G Adler | |
R M Schmid | |||
S Liptay | |||
C Wahl | |||
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P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | sulfasalazine | Q420035 |
P304 | page(s) | 1163-74 | |
P577 | publication date | 1998-03-01 | |
P1433 | published in | Journal of Clinical Investigation | Q3186904 |
P1476 | title | Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B | |
P478 | volume | 101 |
Q40545008 | 15-deoxy-delta12,14-prostaglandin J2-mediated ERK signaling inhibits gram-negative bacteria-induced RelA phosphorylation and interleukin-6 gene expression in intestinal epithelial cells through modulation of protein phosphatase 2A activity |
Q40441268 | 17beta-estradiol inhibits inflammatory gene expression by controlling NF-kappaB intracellular localization |
Q43744333 | 5-Aminosalicylate stimulates phospholipase D activity in macrophages. |
Q33876268 | 5-Aminosalicylic Acid Inhibits Acute Clostridium difficile Toxin A-Induced Colitis in Rats |
Q80337735 | 5-aminosalicylic acid improves indomethacin-induced enteropathy by inhibiting iNOS transcription in rats |
Q36002369 | 5-aminosalicylic acid is an attractive candidate agent for chemoprevention of colon cancer in patients with inflammatory bowel disease |
Q58699124 | A Low Frequency of IL-17-Producing CD8 T-Cells Is Associated With Persistent Immune Activation in People Living With HIV Despite HAART-Induced Viral Suppression |
Q40343429 | A genome-wide expression profile and system-level integration of nuclear factor kappa B regulated genes reveals fundamental metabolic adaptations during cell growth and survival |
Q25257862 | A phase 1-2, prospective, double blind, randomized study of the safety and efficacy of Sulfasalazine for the treatment of progressing malignant gliomas: study protocol of [ISRCTN45828668]. |
Q50547970 | A photoactivatable marker protein for pulse-chase imaging with superresolution. |
Q30445818 | A role for the canonical nuclear factor-κB pathway in coupling neurotrophin-induced differential survival of developing spiral ganglion neurons |
Q34178953 | A yeast-based screen reveals that sulfasalazine inhibits tetrahydrobiopterin biosynthesis. |
Q46439316 | Aberrant expression of microRNAs in T cells from patients with ankylosing spondylitis contributes to the immunopathogenesis |
Q28394186 | Acquired resistance of human T cells to sulfasalazine: stability of the resistant phenotype and sensitivity to non-related DMARDs |
Q41856268 | Acquisition of regulatory function by human CD8(+) T cells treated with anti-CD3 antibody requires TNF |
Q35354271 | Activation of nuclear factor kappaB as a target for anti-inflammatory therapy |
Q41059656 | Activation of the transcription factor NF-kappaB by retrieval is required for long-term memory reconsolidation. |
Q28551369 | Addition of Berberine to 5-Aminosalicylic Acid for Treatment of Dextran Sulfate Sodium-Induced Chronic Colitis in C57BL/6 Mice |
Q35679235 | Agents Which Inhibit NF-κB Signaling Block Spontaneous Contractile Activity and Negatively Influence Survival of Developing Myotubes |
Q52537292 | Aminosalicylic acid inhibits IkappaB kinase alpha phosphorylation of IkappaBalpha in mouse intestinal epithelial cells. |
Q33268281 | An NF-kappaB and slug regulatory loop active in early vertebrate mesoderm |
Q30349885 | Anti-human immunodeficiency virus type 1 microbicide cellulose acetate 1,2-benzenedicarboxylate in a human in vitro model of vaginal inflammation. |
Q38332948 | Anti-inflammatory effect of pelubiprofen, 2-[4-(oxocyclohexylidenemethyl)-phenyl]propionic acid, mediated by dual suppression of COX activity and LPS-induced inflammatory gene expression via NF-κB inactivation |
Q39677660 | Anti-inflammatory mechanism of oxymatrine in dextran sulfate sodium-induced colitis of rats |
Q37927081 | Anti-inflammatory mediators as physiological and pharmacological regulators of parturition. |
Q44786816 | Anti-inflammatory therapy ameliorates leukocyte adhesion and microvascular flow abnormalities in transgenic sickle mice |
Q46147603 | Antifibrotic effect of meloxicam in rat liver: role of nuclear factor kappa B, proinflammatory cytokines, and oxidative stress. |
Q37071320 | Antiinfective agents affecting cognition: a review |
Q37096512 | Application of prodrugs to inflammatory diseases of the gut. |
Q33708645 | Arsenic Trioxide Induces Apoptosis of Fibroblast-like Synoviocytes and Represents Antiarthritis Effect in Experimental Model of Rheumatoid Arthritis |
Q27860821 | Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease |
Q38323803 | Betulinic acid as new activator of NF-kappaB: molecular mechanisms and implications for cancer therapy |
Q43749577 | Butyrate inhibits interleukin-1-mediated nuclear factor-kappa B activation in human epithelial cells |
Q44272936 | Butyrate modulates intestinal epithelial cell-mediated neutrophil migration |
Q40715072 | Calcineurin inhibitors, cyclosporin A and tacrolimus inhibit expression of inducible nitric oxide synthase in colon epithelial and macrophage cell lines. |
Q47844226 | Calcineurin phosphatase as a negative regulator of fear memory in hippocampus: control on nuclear factor-κB signaling in consolidation and reconsolidation |
Q26738536 | Cancer-associated fibroblasts in hepatocellular carcinoma |
Q45096825 | Catalposide, a compound isolated from catalpa ovata, attenuates induction of intestinal epithelial proinflammatory gene expression and reduces the severity of trinitrobenzene sulfonic Acid-induced colitis in mice |
Q35357667 | Cell specific effects of glucocorticoid treatment on the NF-kappaBp65/IkappaBalpha system in patients with Crohn's disease |
Q34079481 | Chronic inflammation and cancer: potential chemoprevention through nuclear factor kappa B and p53 mutual antagonism |
Q30415505 | Chronic inflammatory diseases are stimulated by current lifestyle: how diet, stress levels and medication prevent our body from recovering |
Q34437388 | Chungsim-Yeunja-Tang decreases the inflammatory response in peripheral blood mononuclear cells from patients with cerebral infarction through an NF-κB dependent mechanism |
Q42360841 | Clinical course and prognosis in ulcerative colitis: results from population-based and observational studies |
Q34025193 | Clinical pharmacokinetics of slow release mesalazine |
Q39556601 | Cocoplum (Chrysobalanus icaco L.) anthocyanins exert anti-inflammatory activity in human colon cancer and non-malignant colon cells |
Q37290683 | Colon-targeted delivery of live bacterial cell biotherapeutics including microencapsulated live bacterial cells. |
Q90701307 | Combination Immunotherapy with Passive Antibody and Sulfasalazine Accelerates Fungal Clearance and Promotes the Resolution of Pneumocystis-Associated Immunopathogenesis |
Q47852580 | Combination Therapy with Sulfasalazine and Valproic Acid Promotes Human Glioblastoma Cell Death Through Imbalance of the Intracellular Oxidative Response. |
Q34086102 | Comparative tolerability of treatments for inflammatory bowel disease |
Q42910062 | Comparison of Prostaglandin E2 Receptor Subtype 4 Agonist and Sulfasalazine in Mouse Colitis Prevention and Treatment |
Q57283082 | Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course |
Q37095261 | Conditional knockout of polarity complex (atypical) PKCι reveals an anti-inflammatory function mediated by NF-κB. |
Q30318026 | Conventional basis therapy of rheumatoid arthritis. Effects within and outside cells |
Q44361949 | Curcumin attenuates DNB-induced murine colitis. |
Q38133655 | Current immunotherapy in rheumatoid arthritis |
Q34192660 | Current management of inflammatory bowel disease and colorectal cancer |
Q92977405 | Current perspectives on the immunosuppressive tumor microenvironment in hepatocellular carcinoma: challenges and opportunities |
Q36622124 | Current therapy of inflammatory bowel disease in children |
Q64095457 | Cystine-glutamate antiporter xCT deficiency suppresses tumor growth while preserving antitumor immunity |
Q44368516 | Decrease in activity of smooth muscle L-type Ca2+ channels and its reversal by NF-kappaB inhibitors in Crohn's colitis model |
Q41682361 | Development of a primary microglia screening assay and its use to characterize inhibition of system xc- by erastin and its analogs |
Q28394197 | Development of sulfasalazine resistance in human T cells induces expression of the multidrug resistance transporter ABCG2 (BCRP) and augmented production of TNFalpha |
Q38363570 | Diacerhein and rhein prevent interleukin-1beta-induced nuclear factor-kappaB activation by inhibiting the degradation of inhibitor kappaB-alpha. |
Q44066867 | Different modes of NF-kappaB/Rel activation in pancreatic lobules |
Q31394204 | Disturbed bile secretion and cytochrome P450 function during the acute state of experimental colitis in rats |
Q40725019 | Divergent pathways account for two distinct effects of amyloid beta peptides on exocytosis and Ca(2+) currents: involvement of ROS and NF-kappaB. |
Q33797156 | Diverse agents act at multiple levels to inhibit the Rel/NF-kappaB signal transduction pathway |
Q24298825 | Down-regulation by nuclear factor kappaB of human 25-hydroxyvitamin D3 1alpha-hydroxylase promoter |
Q38645738 | Drugs for Autoimmune Inflammatory Diseases: From Small Molecule Compounds to Anti-TNF Biologics. |
Q80388037 | Dual knockdown of p65 and p50 subunits of NF-kappaB by siRNA inhibits the induction of inflammatory cytokines and significantly enhance apoptosis in human primary synoviocytes treated with tumor necrosis factor-alpha |
Q40672859 | Dual role of the NF-kappaB transcription factor in the death of immature neurons. |
Q33511367 | Early termination of ISRCTN45828668, a phase 1/2 prospective, randomized study of sulfasalazine for the treatment of progressing malignant gliomas in adults |
Q28346425 | Effect of 4-trifluoromethyl derivatives of salicylate on nuclear factor kappaB-dependent transcription in human astrocytoma cells |
Q39814847 | Effect of Thiol-reducing Agents and Antioxidants on Sulfasalazine-induced Hepatic Injury in Normotermic Recirculating Isolated Perfused Rat Liver |
Q24812982 | Effect of a small molecule inhibitor of nuclear factor-kappaB nuclear translocation in a murine model of arthritis and cultured human synovial cells |
Q36784552 | Effect of sulfasalazine on inflammation and endothelial function in patients with established coronary artery disease. |
Q28564809 | Effect of sulfasalazine on renal ischemia/reperfusion injury in rats |
Q90435719 | Effects of Vitex trifolia L. leaf extracts and phytoconstituents on cytokine production in human U937 macrophages |
Q37667524 | Effects of sulfasalazine on lipid peroxidation and histologic liver damage in a rat model of obstructive jaundice and obstructive jaundice with lipopolysaccharide-induced sepsis |
Q43804970 | Effects of tumour necrosis factor-alpha synthesis inhibitors on rat trinitrobenzene sulphonic acid-induced chronic colitis |
Q46319705 | Efficacy of sulphasalazine on lung histopathology in a murine model of chronic asthma |
Q35916725 | Emu oil offers protection in Crohn's disease model in rats |
Q46621544 | Enhanced human beta-defensin-2 (hBD-2) expression by corticosteroids is independent of NF-kappaB in colonic epithelial cells (CaCo2). |
Q46410934 | Epidermal growth factor activates nuclear factor-kappaB in human proximal tubule cells |
Q40688539 | Expression and regulation of glutathione S-transferase P1-1 in cultured human epidermal cells. |
Q40714025 | Expression of interleukin-8, heme oxygenase-1 and vascular endothelial growth factor in DLD-1 colon carcinoma cells exposed to pyrrolidine dithiocarbamate |
Q43539821 | Expression of the NF-kappa B target gene IEX-1 (p22/PRG1) does not prevent cell death but instead triggers apoptosis in Hela cells |
Q73154113 | Failure to activate NF-kappaB promotes apoptosis of retinal ganglion cells following optic nerve transection |
Q40274111 | Fhit protein inhibits cell growth by attenuating the signaling mediated by nuclear factor-kappaB in colon cancer cell lines |
Q39094882 | Fucosylated multiwalled carbon nanotubes for Kupffer cells targeting for the treatment of cytokine-induced liver damage |
Q38348120 | Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis |
Q43687794 | Geldanamycin inhibits NF-kappaB activation and interleukin-8 gene expression in cultured human respiratory epithelium. |
Q40530967 | Gliadin stimulates human monocytes to production of IL-8 and TNF-alpha through a mechanism involving NF-kappaB. |
Q51112994 | Glucocorticoid-induced tumour necrosis factor receptor family related protein (GITR) mediates inflammatory activation of macrophages that can destabilize atherosclerotic plaques. |
Q43687369 | Glucocorticoids and IL-10, but not 6-MP, 5-ASA or sulfasalazine block endothelial expression of MAdCAM-1: implications for inflammatory bowel disease therapy |
Q40684555 | Gold sodium thiomalate (GSTM) inhibits lipopolysaccharide stimulated tumor necrosis factor-alpha through ceramide pathway |
Q36903569 | Green Tea Polyphenols and Sulfasalazine have Parallel Anti-Inflammatory Properties in Colitis Models |
Q37734905 | Hair follicle disruption facilitates pathogenesis to UVB-induced cutaneous inflammation and basal cell carcinoma development in Ptch(+/-) mice |
Q49601734 | Heme oxygenase-1 mediates BAY 11-7085 induced ferroptosis. |
Q28547125 | High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells |
Q83155183 | Hyperbaric oxygen enhances the efficiency of 5-aminosalicylic acid in acetic acid-induced colitis in rats |
Q99411709 | Identification of Target Genes Related to Sulfasalazine in Triple-Negative Breast Cancer Through Network Pharmacology |
Q33893095 | Identification of genomic targets downstream of p38 mitogen-activated protein kinase pathway mediating tumor necrosis factor-alpha signaling |
Q91827723 | Identification of therapeutic targets for inflammation in sickle cell disease (SCD) among Indian patients using gene expression data analysis |
Q37929578 | Immune Modulation as Adjunctive Therapy for Pneumocystis pneumonia |
Q33680480 | Immune Modulation with Sulfasalazine Attenuates Immunopathogenesis but Enhances Macrophage-Mediated Fungal Clearance during Pneumocystis Pneumonia |
Q91054766 | Immunopharmacological effect of β-d-mannuronic acid (M2000), as a new immunosuppressive drug, on gene expression of miR-155 and its target molecules (SOCS1, SHIP1) in a clinical trial on rheumatoid arthritis patients |
Q37165528 | Improving delivery of aminosalicylates in ulcerative colitis: effect on patient outcomes |
Q73082491 | Increased nuclear factor-kappaB activation in colitis of interleukin-2-deficient mice |
Q33868970 | Indications for 5-aminosalicylate in inflammatory bowel disease: is the body of evidence complete? |
Q43289279 | Induction of RIP-2 kinase by proinflammatory cytokines is mediated via NF-kappaB signaling pathways and involves a novel feed-forward regulatory mechanism |
Q35596974 | Induction of T lymphocyte apoptosis by sulphasalazine in patients with Crohn's disease. |
Q39741341 | Induction of laryngeal cancer cell death by Ent-11-hydroxy-15-oxo-kaur-16-en-19-oic acid. |
Q55057352 | Induction with NCB-02 (curcumin) enema for mild-to-moderate distal ulcerative colitis - a randomized, placebo-controlled, pilot study. |
Q38017873 | Inflammatory bowel disease and pregnancy: overlapping pathways |
Q42503199 | Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin |
Q35815842 | Inhibition of System Xc(-) Transporter Attenuates Autoimmune Inflammatory Demyelination |
Q43551315 | Inhibition of nitric oxide synthesis by aminoguanidine increases intestinal damage in the acute phase of rat TNB-colitis |
Q40911348 | Inhibition of nuclear factor kappa B and induction of apoptosis in T-lymphocytes by sulfasalazine |
Q33872837 | Inhibition of nuclear factor kappa-B signaling reduces growth in medulloblastoma in vivo |
Q44462694 | Inhibitors of poly (ADP-ribose) polymerase modulate signal transduction pathways in colitis |
Q37907354 | Inhibitory kappa B Kinases as targets for pharmacological regulation |
Q24536188 | Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression |
Q44409656 | Interferon‐γ induces reactive oxygen species and endoplasmic reticulum stress at the hepatic apoptosis |
Q35748847 | Interleukin-10 inhibits elevated chemokine interleukin-8 and regulated on activation normal T cell expressed and secreted production in cystic fibrosis bronchial epithelial cells by targeting the I(k)B kinase alpha/beta complex |
Q35825309 | Interplaying factors that effect multiple sclerosis causation and sustenance |
Q28184300 | Involvement of nuclear factor-kappa B (NF-kappaB) activation in mitogen-induced lymphocyte proliferation: inhibitory effects of lymphoproliferation by salicylates acting as NF-kappaB inhibitors |
Q92571509 | Ischemia-Reperfusion Injury in Sickle Cell Disease: From Basics to Therapeutics |
Q36561514 | LPS-induced TNF-α factor mediates pro-inflammatory and pro-fibrogenic pattern in non-alcoholic fatty liver disease |
Q54941896 | MUC13 contributes to rewiring of glucose metabolism in pancreatic cancer. |
Q39697425 | Macrophages express membrane bound form of APRIL that can generate immunomodulatory signals |
Q38580123 | Main path and byways: non-vesicular glutamate release by system xc(-) as an important modifier of glutamatergic neurotransmission |
Q36577542 | Mechanisms of disease: Transcription factors in inflammatory arthritis |
Q38220667 | Mechanisms of testicular torsion and potential protective agents |
Q34161820 | Medical therapy for Crohn's disease: the state of the art. |
Q33662010 | Medical therapy for inflammatory bowel disease |
Q34745582 | Medical therapy for ulcerative colitis |
Q30638019 | Mesalamine blocks tumor necrosis factor growth inhibition and nuclear factor kappaB activation in mouse colonocytes |
Q34027828 | Mesalamine for prophylaxis of small bowel Crohn's disease recurrence |
Q40780519 | Mesalamine induces manganese superoxide dismutase in rat intestinal epithelial cell lines and in vivo |
Q40373048 | Mesalamine promotes intestinal epithelial wound healing in vitro through a TGF-beta-independent mechanism |
Q90265833 | Mice Deficient in Epithelial or Myeloid Cell Iκκβ Have Distinct Colonic Microbiomes and Increased Resistance to Citrobacter rodentium Infection |
Q91062672 | Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling |
Q42562683 | Mirror, mirror on the wall: which microbiomes will help heal them all? |
Q34999557 | Miscellaneous treatments, I: sulfasalazine and pentoxifylline: unapproved uses, dosages, or indications |
Q38644746 | Modulation of NF-κB Signaling as a Therapeutic Target in Autoimmunity. |
Q35044669 | Molecular mechanisms of sulfasalazine-induced T-cell apoptosis |
Q36709532 | NF-kappa B as a target for cancer therapy |
Q36709522 | NF-kappa B as a therapeutic target in autoimmune disease. |
Q40814092 | NF-kappaB activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells |
Q44053478 | NF-kappaB activation by hepatitis B virus X (HBx) protein shifts the cellular fate toward survival. |
Q43753204 | NF-kappaB and the MAP kinases/AP-1 pathways are both involved in interleukin-6 and interleukin-8 expression in fibroblast-like synoviocytes stimulated by protein I/II, a modulin from oral streptococci |
Q29614603 | NF-kappaB in cancer: from innocent bystander to major culprit |
Q81768343 | NF-kappaB in carcinoma therapy and prevention |
Q37302741 | NF-kappaB signaling, liver disease and hepatoprotective agents |
Q24303059 | NF-kappaB-dependent expression of the antiapoptotic factor c-FLIP is regulated by calpain 3, the protein involved in limb-girdle muscular dystrophy type 2A |
Q44559483 | NF-kappaB-independent actions of sulfasalazine dissociate the CD95L- and Apo2L/TRAIL-dependent death signaling pathways in human malignant glioma cells |
Q77917939 | NF-kappaB/Rel activation in cerulein pancreatitis |
Q35079912 | NF-kappaB/Rel transcriptional pathway: implications in pancreatic cancer |
Q33930920 | NF-kappaB/rel/IkappaB: implications in gastrointestinal diseases |
Q39142554 | NF-κB as a Therapeutic Target in Inflammatory-Associated Bone Diseases |
Q42717979 | NF-κB subunits are differentially distributed in cells of lumbar dorsal root ganglia in naïve and diabetic rats |
Q37580226 | NSAIDS inhibit in vitro MSC chondrogenesis but not osteogenesis: implications for mechanism of bone formation inhibition in man. |
Q54399200 | Nod2 mutation enhances NF-kappa B activity and bacterial killing activity of macrophages. |
Q35761406 | Non-viral delivery of nuclear factor-kappaB decoy ameliorates murine inflammatory bowel disease and restores tissue homeostasis |
Q44020836 | Nuclear factor (NF)-kappa B blockade attenuates but does not abrogate LPS-mediated interleukin (IL)-1 beta biosynthesis in alveolar epithelial cells |
Q33761124 | Nuclear factor-kappa B (NFkappaB) component p50 in blood mononuclear cells regulates endothelial tissue factor expression in sickle transgenic mice: implications for the coagulopathy of sickle cell disease |
Q28344806 | Nuclear factor-kappa B activation in human testicular apoptosis |
Q46086621 | Nuclear factor-kappa B activation promotes restitution of wounded intestinal epithelial monolayers |
Q37958061 | Nuclear factor-kappa B inhibitors; a patent review (2006-2010). |
Q36085634 | Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs |
Q48475079 | Opposite in vivo effects of agents that stimulate or inhibit the glutamate/cysteine exchanger system xc- on the inhibition of hippocampal LTP by Aß. |
Q44137073 | Osmotic stress sensitizes naturally resistant cells to TNF-alpha-induced apoptosis |
Q38078000 | Oxidative stress and cancer pain. |
Q37827164 | Oxidative stress as a mechanism underlying sulfasalazine-induced toxicity. |
Q38289025 | Oxygen-evoked changes in transcriptional activity of the 5'-flanking region of the human amiloride-sensitive sodium channel (alphaENaC) gene: role of nuclear factor kappaB. |
Q36483981 | Pathophysiology and treatment of stroke in sickle-cell disease: present and future |
Q34162399 | Peroxisome proliferator-activated receptor {delta} regulates inflammation via NF-{kappa}B signaling in polymicrobial sepsis |
Q42414904 | Peroxisome-proliferator-activated receptors and the control of levels of prostaglandin-endoperoxide synthase 2 by arachidonic acid in the bovine uterus |
Q48899356 | Pharmacogenomics of NAT2 and ABCG2 influence the toxicity and efficacy of sulphasalazine containing DMARD regimens in early rheumatoid arthritis. |
Q44324305 | Pharmacologic evaluation of sulfasalazine, FTY720, and anti-IL-12/23p40 in a TNBS-induced Crohn's disease model |
Q39016673 | Pharmacological strategies in lung cancer-induced cachexia: effects on muscle proteolysis, autophagy, structure, and weakness |
Q78353195 | Phosphatase inhibition leads to activation of IkappaB kinase in murine macrophages |
Q35048399 | Plant alkaloid tetrandrine downregulates IkappaBalpha kinases-IkappaBalpha-NF-kappaB signaling pathway in human peripheral blood T cell |
Q40977170 | Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF-kappaB. |
Q33768874 | Pneumocystis carinii activates the NF-kappaB signaling pathway in alveolar epithelial cells |
Q36633307 | Polymorphisms in cytochrome P450 2C19 enzyme and cessation of leflunomide in patients with rheumatoid arthritis |
Q34067424 | Protein degradation by ubiquitin-proteasome system in formation and labilization of contextual conditioning memory |
Q77921896 | Protein kinase C-dependent activation of NF-kappaB in enterocytes is independent of IkappaB degradation |
Q45408799 | Raf-1 and protein kinase B regulate cell survival through the activation of NF-kappaB in hepatitis B virus X-expressing cells |
Q33795121 | Real-time monitoring of nuclear factor kappaB activity in cultured cells and in animal models. |
Q36403180 | Reciprocal regulation of airway rejection by the inducible gas-forming enzymes heme oxygenase and nitric oxide synthase |
Q36274222 | Redox-dependent impairment of vascular function in sickle cell disease |
Q42521488 | Regulation and function of COX-2 gene expression in isolated gastric parietal cells |
Q35609369 | Regulation of nuclear factor-kappaB in intestinal epithelial cells in a cell model of inflammation |
Q37740553 | Requirement of NF-kappa B Activation in Different Mice Brain Areas during Long-Term Memory Consolidation in Two Contextual One-Trial Tasks with Opposing Valences |
Q38631567 | Requirements for two proximal NF-kappaB binding sites and IkappaB-zeta in IL-17A-induced human beta-defensin 2 expression by conducting airway epithelium |
Q39785651 | Reverse signaling through BAFF differentially regulates the expression of inflammatory mediators and cytoskeletal movements in THP-1 cells |
Q28480639 | Role of IKK/NF-κB signaling in extinction of conditioned place aversion memory in rats |
Q34637311 | Role of nuclear factor kappaB in synovial inflammation |
Q37208648 | Salicylates and sulfasalazine, but not glucocorticoids, inhibit leukocyte accumulation by an adenosine-dependent mechanism that is independent of inhibition of prostaglandin synthesis and p105 of NFkappaB. |
Q49357731 | Screening a small molecule library to identify inhibitors of NF-κB inducing kinase and pro-labor genes in human placenta |
Q24683212 | Secretion of interleukin-8 by human-derived cell lines infected with Mycobacterium bovis |
Q24681818 | Selective IgA deficiency (SIgAD) and common variable immunodeficiency (CVID) |
Q34116362 | Series introduction: the transcription factor NF-kappaB and human disease |
Q36546794 | Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome |
Q33598827 | Signal transduction and transcription factors in rheumatic disease |
Q90059434 | Statin administration activates system xC- in skeletal muscle: a potential mechanism explaining statin-induced muscle pain |
Q39620643 | Stimulation of FasL induces production of proinflammatory mediators through activation of mitogen-activated protein kinases and nuclear factor-κB in THP-1 cells |
Q36512479 | Sulfasalazine Treatment Suppresses the Formation of HLA-B27 Heavy Chain Homodimer in Patients with Ankylosing Spondylitis |
Q50449062 | Sulfasalazine and its metabolites inhibit platelet function in patients with inflammatory arthritis. |
Q90079320 | Sulfasalazine as an Immunomodulator of the Inflammatory Process during HIV-1 Infection |
Q40987201 | Sulfasalazine augments a pro-inflammatory response in interleukin-1β-stimulated amniocytes and myocytes. |
Q36906408 | Sulfasalazine blocks the development of tactile allodynia in diabetic rats |
Q41667251 | Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema |
Q39783099 | Sulfasalazine induces apoptosis of HBx-expressing cells in an NF-kappaB-independent manner |
Q45962157 | Sulfasalazine induces haem oxygenase-1 via ROS-dependent Nrf2 signalling, leading to control of neointimal hyperplasia. |
Q36951489 | Sulfasalazine inhibits inflammation and fibrogenesis in pancreas via NF-κB signaling pathway in rats with oxidative stress-induced pancreatic injury |
Q41707939 | Sulfasalazine inhibits reperfusion injury and prolongs allograft survival in rat cardiac transplants |
Q34543666 | Sulfasalazine inhibits the growth of primary brain tumors independent of nuclear factor-kappaB. |
Q78197550 | Sulfasalazine prevents T-helper 1 immune response by suppressing interleukin-12 production in macrophages |
Q40345193 | Sulfasalazine reduces bile acid induced apoptosis in human hepatoma cells and perfused rat livers |
Q51767031 | Sulfasalazine reduces inflammatory renal injury in unilateral ureteral obstruction. |
Q64099971 | Sulfasalazine reduces placental secretion of antiangiogenic factors, up-regulates the secretion of placental growth factor and rescues endothelial dysfunction |
Q40176569 | Sulfasalazine sensitises human monocytic/macrophage cells for glucocorticoids by upregulation of glucocorticoid receptor alpha and glucocorticoid induced apoptosis |
Q43756729 | Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the x(c)- cystine transporter: a new action for an old drug |
Q40416887 | Sulfasalazine-induced renal injury in rats and the protective role of thiol-reductants. |
Q35760185 | Sulphasalazine inhibits human antigen-specific immune responses in vivo |
Q28347747 | Sulphasalazine inhibits macrophage activation: inhibitory effects on inducible nitric oxide synthase expression, interleukin-12 production and major histocompatibility complex II expression |
Q28195124 | Suppression of RelA/p65 nuclear translocation independent of IkappaB-alpha degradation by cyclooxygenase-2 inhibitor in gastric cancer |
Q37873270 | Survival of Chlamydia pneumoniae-infected Mono Mac 6 cells is dependent on NF-kappaB binding activity |
Q31386037 | Synergistic activation of NF-kappab and inducible isoform of nitric oxide synthase induction by interferon-gamma and tumor necrosis factor-alpha in INS-1 cells |
Q81580785 | TNF-alpha enhances estrogen-induced cell proliferation of estrogen-dependent breast tumor cells through a complex containing nuclear factor-kappa B |
Q59091118 | Tackling common disease |
Q37293344 | Targeting NF-kappaB: a promising molecular therapy in inflammatory arthritis. |
Q40195204 | Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia. |
Q31874663 | The "in vivo" and "ex vivo" roles of cylcooxygenase-2, nuclear factor-kappaB and protein kinases pathways in the up-regulation of B1 receptor-mediated contraction of the rabbit aorta |
Q37262181 | The 5-aminosalicylic acid antineoplastic effect in the intestine is mediated by PPARγ. |
Q35621375 | The IKK NF-kappa B system: a treasure trove for drug development |
Q28202240 | The IkappaB kinase inhibitor sulfasalazine impairs long-term memory in the crab Chasmagnathus |
Q41652035 | The IkappaB kinase regulates chromatin structure during reconsolidation of conditioned fear memories. |
Q51796373 | The NF-kappaB inhibitors attenuate hepatic injury in bile duct ligated rats. |
Q91872236 | The Role of Iron Regulation in Immunometabolism and Immune-Related Disease |
Q38350256 | The Role of Nuclear Factor κB in Tumor Necrosis Factor-Regulated Transcription of the Human μ-Opioid Receptor Gene |
Q34537041 | The apolipoprotein E-mimetic peptide COG112 inhibits NF-kappaB signaling, proinflammatory cytokine expression, and disease activity in murine models of colitis |
Q36711167 | The apolipoprotein E-mimetic peptide COG112 inhibits the inflammatory response to Citrobacter rodentium in colonic epithelial cells by preventing NF-kappaB activation |
Q34279067 | The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities. |
Q38648460 | The effect of gene polymorphisms on patient responses to rheumatoid arthritis therapy. |
Q43436561 | The effects of fenofibrate on inflammation and cardiovascular markers in patients with active rheumatoid arthritis: a pilot study |
Q90751062 | The inflammatory cytokine TNF contributes with RAC3-induced malignant transformation |
Q45414539 | The involvement of nuclear factor-kappa B in cyclooxygenase-2 overexpression in murine colon cancer cells transduced with herpes simplex virus thymidine kinase gene |
Q33729031 | The levels of RAC3 expression are up regulated by TNF in the inflammatory response |
Q40891401 | The luminal short-chain fatty acid butyrate modulates NF-kappaB activity in a human colonic epithelial cell line |
Q40931699 | The non-steroidal anti-inflammatory drug tepoxalin inhibits interleukin-6 and alpha1-anti-chymotrypsin synthesis in astrocytes by preventing degradation of IkappaB-alpha |
Q90430035 | The p38 MAPK Inhibitor SB203580 Abrogates Tumor Necrosis Factor-Induced Proliferative Expansion of Mouse CD4+Foxp3+ Regulatory T Cells |
Q40660116 | The p38 mitogen-activated protein kinase regulates interleukin-1beta-induced IL-8 expression via an effect on the IL-8 promoter in intestinal epithelial cells. |
Q47657684 | The protective role of NF-kappaB and AP-1 in arsenite-induced apoptosis in aortic endothelial cells |
Q36105771 | The transcription factor NF-kappaB as drug target |
Q46555801 | The treatment of juvenile rheumatism: pharmacotherapy |
Q30856787 | Therapeutic effect of intracolonically administered nuclear factor kappa B (p65) antisense oligonucleotide on mouse dextran sulphate sodium (DSS)-induced colitis |
Q24681630 | Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer |
Q33770277 | Therapeutic targets for hypoxia-elicited pathways |
Q43737657 | Tranilast inhibits interleukin-1beta-induced monocyte chemoattractant protein-1 expression in rat mesangial cells |
Q40837199 | Transrepression of NF-kappaB is not required for glucocorticoid-mediated protection of TNF-alpha-induced apoptosis on fibroblasts. |
Q42230752 | Treatment of diarrhea-predominant irritable bowel syndrome with mesalazine and/or Saccharomyces boulardii |
Q38906880 | Treatment of endotoxaemia and septicaemia in the equine patient |
Q26853183 | Treatment of inflammatory bowel disease (IBD) |
Q34182017 | Treatment of postinfectious irritable bowel syndrome and noninfective irritable bowel syndrome with mesalazine |
Q42478402 | Treatment with sulfasalazine or sulfapyridine, but not 5-aminosalicyclic acid, inhibits basic fibroblast growth factor-induced endothelial cell chemotaxis |
Q39890706 | Tumor necrosis factor-alpha causes accumulation of a ubiquitinated form of hypoxia inducible factor-1alpha through a nuclear factor-kappaB-dependent pathway |
Q43005466 | Tumour necrosis factor alpha and nuclear factor kappaB inhibit transcription of human TFF3 encoding a gastrointestinal healing peptide |
Q42437041 | Usage of the NF-kappaB inhibitor sulfasalazine as sensitizing agent in combined chemotherapy of pancreatic cancer |
Q38505246 | Yulda-Hanso-Tang attenuates the endotoxin-induced inflammatory cytokine production in peripheral blood mononuclear cells |
Q98386393 | xCT inhibitor sulfasalazine depletes paclitaxel-resistant tumor cells through ferroptosis in uterine serous carcinoma |
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