Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin

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Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1035971307
P356DOI10.1038/SJ.ONC.1204168
P698PubMed publication ID11314019
P5875ResearchGate publication ID12020831

P50authorAlexander ArltQ37830388
P2093author name stringH Kalthoff
H Schäfer
U R Fölsch
W E Schmidt
J Vorndamm
M Breitenbroich
P2860cites workThe Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulatorsQ22009958
NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosisQ24554454
Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa BQ28379350
TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaBQ29614706
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell deathQ29620021
Control of apoptosis by Rel/NF-kappaB transcription factorsQ33797163
Transcriptional activation by NF-kappaB requires multiple coactivatorsQ33959552
The promoter of human p22/PACAP response gene 1 (PRG1) contains functional binding sites for the p53 tumor suppressor and for NFkappaB.Q34476192
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.Q35207550
The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB.Q36366520
In vitro chromatin assembly of the HIV-1 promoter. ATP-dependent polar repositioning of nucleosomes by Sp1 and NFkappaB.Q38344316
Mutations of human topoisomerase II alpha affecting multidrug resistance and sensitivity.Q40934854
Salicylates inhibit NF-kappaB activation and enhance TNF-alpha-induced apoptosis in human pancreatic cancer cellsQ40959356
Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.Q40972388
Protein kinase Cdelta-dependent induction of manganese superoxide dismutase gene expression by microtubule-active anticancer drugsQ40988602
Rel blocks both anti-Fas- and TNF alpha-induced apoptosis and an intact Rel transactivation domain is essential for this effectQ40989488
Interleukin-1 protects transformed keratinocytes from tumor necrosis factor-related apoptosis-inducing ligandQ41000355
p53 gene status and chemosensitivity of childhood acute lymphoblastic leukemia cells to adriamycinQ42480281
Neuronal apoptosis induced by histone deacetylase inhibitorsQ48363398
Decreased expression of transforming growth factor alpha during differentiation of human pancreatic cancer cellsQ67593971
Differentiation of pancreatic carcinoma induced by retinoic acid or sodium butyrate: a morphological and molecular analysis of four cell linesQ71672648
The response of eukaryotic topoisomerases to DNA damageQ77333775
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
etoposideQ418817
apoptotic processQ14599311
pancreatic carcinomaQ18556536
P304page(s)859-868
P577publication date2001-02-01
P1433published inOncogeneQ1568657
P1476titleInhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin
P478volume20

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