| scholarly article | Q13442814 |
| P2093 | author name string | Jerrold R Turner | |
| Le Shen | |||
| Liping Su | |||
| Christopher R Weber | |||
| David R Raleigh | |||
| Yingmin Wang | |||
| Erika A Sullivan | |||
| P2860 | cites work | Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability | Q24317362 |
| Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression | Q24536188 | ||
| Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells | Q28214827 | ||
| IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis | Q28285105 | ||
| Infliximab for induction and maintenance therapy for ulcerative colitis | Q28285876 | ||
| Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis | Q30476106 | ||
| Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo | Q34014510 | ||
| Akt2 phosphorylates ezrin to trigger NHE3 translocation and activation | Q34049636 | ||
| Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane | Q34049874 | ||
| Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease | Q34145454 | ||
| Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis. | Q34321127 | ||
| Defects in mucosal immunity leading to ulcerative colitis | Q34437552 | ||
| Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution | Q34440722 | ||
| Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo | Q35052412 | ||
| IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction | Q35215366 | ||
| Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application | Q35569905 | ||
| Genetic basis for increased intestinal permeability in families with Crohn's disease: role of CARD15 3020insC mutation? | Q35760212 | ||
| Inflammatory bowel disease: is it really just another break in the wall? | Q35761217 | ||
| Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells | Q36316586 | ||
| Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation | Q36982054 | ||
| Molecular basis for cation selectivity in claudin-2-based paracellular pores: identification of an electrostatic interaction site | Q37023274 | ||
| LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms. | Q37259782 | ||
| Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. | Q37266104 | ||
| Structure-function studies of claudin extracellular domains by cysteine-scanning mutagenesis. | Q37431293 | ||
| AMP-activated protein kinase mediates the interferon-gamma-induced decrease in intestinal epithelial barrier function | Q37459893 | ||
| Interleukins 4 and 13 increase intestinal epithelial permeability by a phosphatidylinositol 3-kinase pathway. Lack of evidence for STAT 6 involvement. | Q38311009 | ||
| The density of small tight junction pores varies among cell types and is increased by expression of claudin-2. | Q40024709 | ||
| Selective induction of apoptosis by histone deacetylase inhibitor SAHA in cutaneous T-cell lymphoma cells: relevance to mechanism of therapeutic action | Q40349894 | ||
| Invasion of v-Fos(FBR)-transformed cells is dependent upon histone deacetylase activity and suppression of histone deacetylase regulated genes | Q40563088 | ||
| Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms | Q40614064 | ||
| Tumor necrosis factor-alpha increases sodium and chloride conductance across the tight junction of CACO-2 BBE, a human intestinal epithelial cell line. | Q41061126 | ||
| Phosphatidylinositol 3-kinase mediates the inhibitory effect of epidermal growth factor on calcium-dependent chloride secretion | Q41157432 | ||
| Permeability of the rat small intestinal epithelium along the villus-crypt axis: effects of glucose transport | Q42494774 | ||
| Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells | Q44217456 | ||
| IL-13 signaling via IL-13R alpha2 induces major downstream fibrogenic factors mediating fibrosis in chronic TNBS colitis | Q46306807 | ||
| Infliximab as rescue therapy in severe to moderately severe ulcerative colitis: a randomized, placebo-controlled study. | Q46531976 | ||
| Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells. | Q46592696 | ||
| Interferon-gamma selectively increases epithelial permeability to large molecules by activating different populations of paracellular pores | Q47608346 | ||
| Both the lymphotoxin and tumor necrosis factor pathways are involved in experimental murine models of colitis | Q48709458 | ||
| Autocrine regulation of epithelial permeability by hypoxia: role for polarized release of tumor necrosis factor alpha. | Q51525902 | ||
| Functional coupling of tight junctions and microfilaments in T84 monolayers. | Q52491565 | ||
| A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease. | Q53965794 | ||
| Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2). | Q54005785 | ||
| Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure | Q57179984 | ||
| Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factor | Q69656337 | ||
| Is small intestinal permeability really increased in relatives of patients with Crohn's disease? | Q70734227 | ||
| Intestinal permeability and the prediction of relapse in Crohn's disease | Q72220492 | ||
| Intestinal permeability test as a predictor of clinical course in Crohn's disease | Q73081946 | ||
| Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation | Q73847660 | ||
| Regulatory sequences of the mouse villin gene that efficiently drive transgenic expression in immature and differentiated epithelial cells of small and large intestines | Q74485164 | ||
| Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease | Q82215769 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 16 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | interleukins | Q194908 |
| P304 | page(s) | 12037-12046 | |
| P577 | publication date | 2010-02-22 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity | |
| P478 | volume | 285 |
| Q40627574 | 1,25-Dihydroxyvitamin D Protects Intestinal Epithelial Barrier by Regulating the Myosin Light Chain Kinase Signaling Pathway |
| Q50220919 | Abnormal Barrier Function in Gastrointestinal Disorders. |
| Q46877467 | Adalimumab prevents barrier dysfunction and antagonizes distinct effects of TNF-α on tight junction proteins and signaling pathways in intestinal epithelial cells |
| Q28487645 | Amelioration of IFN-γ and TNF-α-induced intestinal epithelial barrier dysfunction by berberine via suppression of MLCK-MLC phosphorylation signaling pathway |
| Q90363154 | Analysis of Faecal Zonulin and Calprotectin Concentrations in Healthy Children During the First Two Years of Life. An Observational Prospective Cohort Study |
| Q54333269 | Anti-mouse CD52 monoclonal antibody ameliorates intestinal epithelial barrier function in interleukin-10 knockout mice with spontaneous chronic colitis. |
| Q39492213 | Bifidobacterium breve - HT-29 cell line interaction: modulation of TNF-α induced gene expression |
| Q35592017 | Bovine immunoglobulin/protein isolate binds pro-inflammatory bacterial compounds and prevents immune activation in an intestinal co-culture model |
| Q34328430 | CRF induces intestinal epithelial barrier injury via the release of mast cell proteases and TNF-α. |
| Q34299341 | Calcium inhibits paracellular sodium conductance through claudin-2 by competitive binding |
| Q40110229 | Campylobacter jejuni impairs sodium transport and epithelial barrier function via cytokine release in human colon. |
| Q38194340 | Cardiac to cancer: connecting connexins to clinical opportunity. |
| Q33788423 | Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo |
| Q39308269 | Cell Biology of Tight Junction Barrier Regulation and Mucosal Disease |
| Q36113266 | Cellular and molecular basis of intestinal barrier dysfunction in the irritable bowel syndrome. |
| Q35212830 | Claudin-2 as a mediator of leaky gut barrier during intestinal inflammation |
| Q39212748 | Claudin-2 regulates colorectal inflammation via myosin light chain kinase-dependent signaling. |
| Q36585920 | Claudin-2-dependent paracellular channels are dynamically gated. |
| Q34650517 | Claudins and the modulation of tight junction permeability |
| Q27000548 | Claudins in intestines: Distribution and functional significance in health and diseases |
| Q92923684 | Computational Modeling of Claudin Structure and Function |
| Q26861369 | Conceptual barriers to understanding physical barriers |
| Q39200576 | Contributions of intestinal epithelial barriers to health and disease |
| Q28273481 | Crohn's disease |
| Q27303623 | Cryptosporidium Priming Is More Effective than Vaccine for Protection against Cryptosporidiosis in a Murine Protein Malnutrition Model |
| Q101567971 | Culture of Intestinal Epithelial Cell Monolayers and Their Use in Multiplex Macromolecular Permeability Assays for In Vitro Analysis of Tight Junction Size Selectivity |
| Q33701592 | Cyclic stretch disrupts apical junctional complexes in Caco-2 cell monolayers by a JNK-2-, c-Src-, and MLCK-dependent mechanism |
| Q37973313 | Determinants of colonic barrier function in inflammatory bowel disease and potential therapeutics |
| Q40495815 | Development of an in vitro co-culture model to mimic the human intestine in healthy and diseased state |
| Q90663506 | Differential regulation of claudin-2 and claudin-15 expression in children and adults with malabsorptive disease |
| Q37742981 | Disruption of the TWEAK/Fn14 pathway prevents 5-fluorouracil-induced diarrhea in mice |
| Q104135043 | Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers |
| Q35075855 | Duodenal helminth infection alters barrier function of the colonic epithelium via adaptive immune activation |
| Q47806206 | Dynamic modeling of the tight junction pore pathway |
| Q43121604 | Dynamic properties of the tight junction barrier |
| Q47795925 | Epithelial Organization: The Gut and Beyond |
| Q35618798 | Experimental Models of Inflammatory Bowel Diseases |
| Q39376100 | From clinical uncertainties to precision medicine: the emerging role of the gut barrier and microbiome in small bowel functional diseases |
| Q45743243 | Glucocorticoids regulate barrier function and claudin expression in intestinal epithelial cells via MKP-1. |
| Q37559869 | Gluten-induced symptoms in diarrhea-predominant irritable bowel syndrome are associated with increased myosin light chain kinase activity and claudin-15 expression |
| Q64229900 | Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability |
| Q49938175 | Gut Epithelial Vitamin D Receptor Regulates Microbiota-Dependent Mucosal Inflammation by Suppressing Intestinal Epithelial Cell Apoptosis |
| Q39102508 | Gut permeability and mucosal inflammation: bad, good or context dependent. |
| Q38348536 | Hereditary barrier-related diseases involving the tight junction: lessons from skin and intestine |
| Q43184075 | IBD candidate genes and intestinal barrier regulation |
| Q47758483 | IL-22 Increases Permeability of Intestinal Epithelial Tight Junctions by Enhancing Claudin-2 Expression. |
| Q40171045 | IL-22 Upregulates Epithelial Claudin-2 to Drive Diarrhea and Enteric Pathogen Clearance |
| Q53278465 | Inflammation Controls Sensitivity of Human and Mouse Intestinal Epithelial Cells to Galectin-1. |
| Q38902578 | Inflammation and the Intestinal Barrier: Leukocyte-Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair |
| Q51009956 | Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis. |
| Q44068457 | Innate immune factors in the development and maintenance of pouchitis |
| Q34787194 | Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion. |
| Q36727971 | Interleukin-13 Receptor α1-Dependent Responses in the Intestine Are Critical to Parasite Clearance |
| Q42770580 | Interleukin-4 and interleukin-13 cause barrier dysfunction in human airway epithelial cells |
| Q38417912 | Interleukin-6 (IL-6) regulates claudin-2 expression and tight junction permeability in intestinal epithelium |
| Q89886066 | Intestinal Barrier Dysfunction, LPS Translocation, and Disease Development |
| Q92356819 | Intestinal barrier dysfunction in severe burn injury |
| Q38460376 | Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease |
| Q39298268 | Intestinal epithelial claudins: expression and regulation in homeostasis and inflammation |
| Q24629228 | Intestinal permeability defects: is it time to treat? |
| Q47382531 | Lipopolysaccharide-Induced Increase in Intestinal Epithelial Tight Permeability Is Mediated by Toll-Like Receptor 4/Myeloid Differentiation Primary Response 88 (MyD88) Activation of Myosin Light Chain Kinase Expression |
| Q36057629 | MARCKS-dependent mucin clearance and lipid metabolism in ependymal cells are required for maintenance of forebrain homeostasis during aging |
| Q38685179 | MPA Modulates Tight Junctions' Permeability via Midkine/PI3K Pathway in Caco-2 Cells: A Possible Mechanism of Leak-Flux Diarrhea in Organ Transplanted Patients |
| Q33729648 | Maternal obesity induces gut inflammation and impairs gut epithelial barrier function in nonobese diabetic mice |
| Q36382078 | Matrix metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitis |
| Q36296995 | Mechanism of interleukin-1β induced-increase in mouse intestinal permeability in vivo |
| Q36100701 | MicroRNA-346 mediates tumor necrosis factor α-induced downregulation of gut epithelial vitamin D receptor in inflammatory bowel diseases |
| Q41834962 | Modified Pulsatilla decoction attenuates oxazolone-induced colitis in mice through suppression of inflammation and epithelial barrier disruption |
| Q52691745 | Modulation of Intestinal Paracellular Transport by Bacterial Pathogens. |
| Q34789106 | Modulation of lipopolysaccharide-induced neuronal response by activation of the enteric nervous system |
| Q52609696 | Molecular Pathophysiology of Epithelial Barrier Dysfunction in Inflammatory Bowel Diseases. |
| Q26864785 | Molecular aspects of tight junction barrier function |
| Q89143916 | Molecular determination of claudin-15 organization and channel selectivity |
| Q43474062 | Myosin light chain kinase inhibitor inhibits dextran sulfate sodium-induced colitis in mice |
| Q31057409 | Myosin light chain kinase mediates intestinal barrier disruption following burn injury |
| Q36062835 | Myosin light chain kinase: pulling the strings of epithelial tight junction function |
| Q38809434 | Neutrophil-Epithelial Interactions: A Double-Edged Sword |
| Q42811392 | Nonmuscle myosin light-chain kinase deficiency attenuates atherosclerosis in apolipoprotein E-deficient mice via reduced endothelial barrier dysfunction and monocyte migration |
| Q33894841 | Obesity-induces Organ and Tissue Specific Tight Junction Restructuring and Barrier Deregulation by Claudin Switching |
| Q30009590 | Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux |
| Q34918139 | Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function |
| Q26738728 | Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues |
| Q28507355 | Overexpression of Ste20-related proline/alanine-rich kinase exacerbates experimental colitis in mice |
| Q37728541 | Phosphatase regulation of intercellular junctions |
| Q28513418 | Predicted expansion of the claudin multigene family |
| Q26774570 | Protein tyrosine phosphatase non-receptor type 2 and inflammatory bowel disease |
| Q34287155 | Regulation of intestinal epithelial permeability by tight junctions. |
| Q38141920 | Regulation of paracellular permeability: factors and mechanisms. |
| Q30421083 | Role of Corticotropin-releasing Factor in Gastrointestinal Permeability. |
| Q35085007 | Role of protein tyrosine phosphatases in regulating the immune system: implications for chronic intestinal inflammation |
| Q53644116 | SEW2871 protects from experimental colitis through reduced epithelial cell apoptosis and improved barrier function in interleukin-10 gene-deficient mice. |
| Q35061825 | STAT6 activation in ulcerative colitis: a new target for prevention of IL-13-induced colon epithelial cell dysfunction |
| Q36586297 | STAT6 deficiency ameliorates severity of oxazolone colitis by decreasing expression of claudin-2 and Th2-inducing cytokines |
| Q34313951 | Sepsis enhances epithelial permeability with stretch in an actin dependent manner. |
| Q24621817 | Side-stream smoking reduces intestinal inflammation and increases expression of tight junction proteins |
| Q37308921 | Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1. |
| Q46115480 | T cell protein tyrosine phosphatase prevents STAT1 induction of claudin-2 expression in intestinal epithelial cells. |
| Q37042932 | TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis. |
| Q90138792 | Targeted Intestinal Tight Junction Hyperpermeability Alters the Microbiome, Behavior, and Visceromotor Responses |
| Q36174448 | Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2, and antibacterial peptides |
| Q40099296 | The Microbiome Activates CD4 T-cell-mediated Immunity to Compensate for Increased Intestinal Permeability |
| Q91722641 | The cerebral cavernous malformation disease causing gene KRIT1 participates in intestinal epithelial barrier maintenance and regulation |
| Q37798825 | The enteric nervous system as a regulator of intestinal epithelial barrier function in health and disease |
| Q39009998 | The intestinal epithelial barrier: a therapeutic target? |
| Q39071909 | The mucosal barrier at a glance. |
| Q34617424 | The role of molecular remodeling in differential regulation of tight junction permeability |
| Q87883932 | Therapeutic activity of an interleukin-4/interleukin-13 dual antagonist on oxazolone-induced colitis in mice |
| Q36305755 | Tight Junction Pore and Leak Pathways: A Dynamic Duo |
| Q61811129 | Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk |
| Q26752750 | Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer |
| Q36950607 | Tight junctions on the move: molecular mechanisms for epithelial barrier regulation |
| Q89744172 | Total Flavonoid Extract from Hawthorn (Crataegus pinnatifida) Improves Inflammatory Cytokines-Evoked Epithelial Barrier Deficit |
| Q90296333 | Total polysaccharides of the Sijunzi decoction attenuate tumor necrosis factor-α-induced damage to the barrier function of a Caco-2 cell monolayer via the nuclear factor-κB-myosin light chain kinase-myosin light chain pathway |
| Q38671207 | Tricellulin is regulated via interleukin-13-receptor α2, affects macromolecule uptake, and is decreased in ulcerative colitis. |
| Q35012750 | Tumor necrosis factor-neuropeptide Y cross talk regulates inflammation, epithelial barrier functions, and colonic motility |
| Q50920142 | Tumour necrosis factor--induced loss of intestinal barrier function requires TNFR1 and TNFR2 signalling in a mouse model of total parenteral nutrition. |
| Q43517624 | Vasoactive intestinal polypeptide regulates barrier function via mast cells in human intestinal follicle-associated epithelium and during stress in rats. |
| Q64940620 | Villus Growth, Increased Intestinal Epithelial Sodium Selectivity, and Hyperaldosteronism Are Mechanisms of Adaptation in a Murine Model of Short Bowel Syndrome. |
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