scholarly article | Q13442814 |
P50 | author | Eugene B Chang | Q88434885 |
P2093 | author name string | Mark W Musch | |
Jerrold R Turner | |||
Yingmin Wang | |||
Harn Shiue | |||
P2860 | cites work | Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10 | Q24291135 |
Mechanism of activation of protein kinase B by insulin and IGF-1 | Q24309528 | ||
NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrin | Q24315976 | ||
The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain | Q24316456 | ||
Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site | Q24617964 | ||
Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway | Q24648522 | ||
Lipid Raft targeting of the TC10 amino terminal domain is responsible for disruption of adipocyte cortical actin | Q24669996 | ||
Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs | Q24671990 | ||
Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin | Q24676944 | ||
Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association | Q24678197 | ||
Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane | Q24683879 | ||
Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain | Q27622801 | ||
The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin | Q28190100 | ||
Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeleton | Q28202663 | ||
Cyclic AMP-dependent protein kinase phosphorylates merlin at serine 518 independently of p21-activated kinase and promotes merlin-ezrin heterodimerization | Q28246519 | ||
Na+-H+ exchanger 3 (NHE3) is present in lipid rafts in the rabbit ileal brush border: a role for rafts in trafficking and rapid stimulation of NHE3 | Q28365699 | ||
Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motility | Q28366134 | ||
Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells | Q28586458 | ||
NHERF-1 uniquely transduces the cAMP signals that inhibit sodium-hydrogen exchange in mouse renal apical membranes | Q28586939 | ||
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) | Q28640016 | ||
ERM proteins and merlin: integrators at the cell cortex | Q29619893 | ||
Carboxy-terminal vesicular stomatitis virus G protein-tagged intestinal Na+-dependent glucose cotransporter (SGLT1): maintenance of surface expression and global transport function with selective perturbation of transport kinetics and polarized expr | Q30423828 | ||
Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation | Q30441963 | ||
Toward a PKB inhibitor: modification of a selective PKA inhibitor by rational design | Q30840946 | ||
Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions | Q30925087 | ||
The lateral mobility of NHE3 on the apical membrane of renal epithelial OK cells is limited by the PDZ domain proteins NHERF1/2, but is dependent on an intact actin cytoskeleton as determined by FRAP. | Q33204357 | ||
Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor. | Q34333813 | ||
ERM proteins and NF2 tumor suppressor: the Yin and Yang of cortical actin organization and cell growth signaling | Q34495193 | ||
Ezrin regulates NHE3 translocation and activation after Na+-glucose cotransport. | Q35322212 | ||
Association of the myosin-binding subunit of myosin phosphatase and moesin: dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase | Q36289185 | ||
RhoA-dependent phosphorylation and relocalization of ERM proteins into apical membrane/actin protrusions in fibroblasts | Q38610718 | ||
Ezrin function is required for ROCK-mediated fibroblast transformation by the Net and Dbl oncogenes | Q40370592 | ||
Akt-dependent phosphorylation negatively regulates the transcriptional activity of dHAND by inhibiting the DNA binding activity | Q40529059 | ||
Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling | Q40540364 | ||
The NHE1 Na+/H+ exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival. | Q40564766 | ||
Inhibition and redistribution of NHE3, the apical Na+/H+ exchanger, by Clostridium difficile toxin B. | Q40567906 | ||
Akt kinase activation blocks apoptosis in intestinal epithelial cells by inhibiting caspase-3 after polyamine depletion | Q40578104 | ||
Ca2+-dependent inhibition of NHE3 requires PKC alpha which binds to E3KARP to decrease surface NHE3 containing plasma membrane complexes | Q40637935 | ||
Lysophosphatidic acid stimulates brush border Na+/H+ exchanger 3 (NHE3) activity by increasing its exocytosis by an NHE3 kinase A regulatory protein-dependent mechanism | Q40669337 | ||
Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity | Q40679590 | ||
Differential effects of phosphatidylinositol 3-kinase inhibition on intracellular signals regulating GLUT4 translocation and glucose transport | Q40775117 | ||
Ezrin binding domain-deficient NHERF attenuates cAMP-mediated inhibition of Na(+)/H(+) exchange in OK cells | Q40791959 | ||
Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo | Q40915136 | ||
The role of NHERF and E3KARP in the cAMP-mediated inhibition of NHE3. | Q40999069 | ||
Phosphoinositide 3-kinase is required for insulin-induced but not for growth hormone- or hyperosmolarity-induced glucose uptake in 3T3-L1 adipocytes | Q42443687 | ||
Akt2, phosphatidylinositol 3-kinase, and PTEN are in lipid rafts of intestinal cells: role in absorption and differentiation | Q42454922 | ||
An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes | Q42470059 | ||
Constitutively active phosphatidylinositol 3-kinase and AKT are sufficient to stimulate the epithelial Na+/H+ exchanger 3. | Q42504933 | ||
Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family | Q42720142 | ||
Activation of ERM proteins in vivo by Rho involves phosphatidyl-inositol 4-phosphate 5-kinase and not ROCK kinases | Q42809055 | ||
Rho-dependent and -independent activation mechanisms of ezrin/radixin/moesin proteins: an essential role for polyphosphoinositides in vivo. | Q42814440 | ||
Protein kinase B/AKT 1 plays a pivotal role in insulin-like growth factor-1 receptor signaling induced 3T3-L1 adipocyte differentiation | Q42828148 | ||
NHE3-dependent cytoplasmic alkalinization is triggered by Na(+)-glucose cotransport in intestinal epithelia | Q43766328 | ||
A dileucine motif targets the sulfate anion transporter sat-1 to the basolateral membrane in renal cell lines | Q44834860 | ||
Requirement of the epidermal growth factor receptor in renal epithelial cell proliferation and migration | Q47303356 | ||
Role of p38 MAPK and MAPKAPK-2 in angiotensin II-induced Akt activation in vascular smooth muscle cells | Q47764569 | ||
Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger | Q47852356 | ||
Soluble ezrin purified from placenta exists as stable monomers and elongated dimers with masked C-terminal ezrin-radixin-moesin association domains | Q70801487 | ||
The apical Na(+)/H(+) exchanger isoform NHE3 is regulated by the actin cytoskeleton | Q73066614 | ||
RhoA and rho kinase regulate the epithelial Na+/H+ exchanger NHE3. Role of myosin light chain phosphorylation | Q73992917 | ||
Protein kinase C-theta phosphorylation of moesin in the actin-binding sequence | Q74358920 | ||
Cutting edge: negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly | Q77452189 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phosphorylation | Q242736 |
P304 | page(s) | 1688-1695 | |
P577 | publication date | 2004-11-04 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Akt2 phosphorylates ezrin to trigger NHE3 translocation and activation | |
P478 | volume | 280 |
Q37608417 | AKT and GSK-3 are necessary for direct ezrin binding to NHE3 as part of a C-terminal stimulatory complex: role of a novel Ser-rich NHE3 C-terminal motif in NHE3 activity and trafficking |
Q35104869 | Akt inhibitor MK-2206 promotes anti-tumor activity and cell death by modulation of AIF and Ezrin in colorectal cancer |
Q54638508 | Anti-apoptotic PI3K/Akt signaling by sodium/glucose transporter 1 reduces epithelial barrier damage and bacterial translocation in intestinal ischemia. |
Q36540696 | Atypical protein kinase C (iota) activates ezrin in the apical domain of intestinal epithelial cells |
Q36698786 | Beyond Ussing's chambers: contemporary thoughts on integration of transepithelial transport |
Q57107234 | Bile acids inhibit Na⁺/H⁺ exchanger and Cl⁻/HCO₃⁻ exchanger activities via cellular energy breakdown and Ca²⁺ overload in human colonic crypts |
Q36805316 | Comparative study of ezrin phosphorylation among different tissues: more is good; too much is bad. |
Q89578153 | Contributions of Myosin Light Chain Kinase to Regulation of Epithelial Paracellular Permeability and Mucosal Homeostasis |
Q36704497 | Coupling between apical and paracellular transport processes |
Q42586814 | D-Glucose Acts via Sodium/Glucose Cotransporter 1 to Increase NHE3 in Mouse Jejunal Brush Border by a Na+/H+ Exchange Regulatory Factor 2–Dependent Process |
Q40738109 | Diet induced obesity in rats reduces NHE3 and Na(+) /K(+) -ATPase expression in the kidney. |
Q24322564 | EGF receptor transactivation and PI3-kinase mediate stimulation of ERK by alpha(2A)-adrenoreceptor in intestinal epithelial cells: a role in wound healing |
Q47938284 | ERM protein moesin is phosphorylated by advanced glycation end products and modulates endothelial permeability |
Q33698044 | Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin gene |
Q33782512 | Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity |
Q37682332 | Ezrin expression and cell survival regulation in colorectal cancer |
Q28251491 | Ezrin induces long-range interdomain allostery in the scaffolding protein NHERF1 |
Q36369093 | Ezrin interacts with S100A4 via both its N- and C-terminal domains. |
Q50697750 | Ezrin/moesin in motile Walker 256 carcinosarcoma cells: signal-dependent relocalization and role in migration. |
Q36320446 | Fluid shear triggers microvilli formation via mechanosensitive activation of TRPV6 |
Q42848424 | Functional role of glucose metabolism, osmotic stress, and sodium-glucose cotransporter isoform-mediated transport on Na+/H+ exchanger isoform 3 activity in the renal proximal tubule |
Q30497357 | Glucose-induced ERM protein activation and translocation regulates insulin secretion |
Q46102053 | High turnover of ezrin T567 phosphorylation: conformation, activity, and cellular function |
Q40131520 | Hsp27 regulates Akt activation and polymorphonuclear leukocyte apoptosis by scaffolding MK2 to Akt signal complex |
Q34985526 | Insulin resistance, obesity, hypertension, and renal sodium transport |
Q29618086 | Intestinal mucosal barrier function in health and disease |
Q37510693 | Involvement of Akt in neurite outgrowth |
Q39717269 | Knockdown of moesin expression accelerates cellular senescence of human dermal microvascular endothelial cells. |
Q46601631 | Lumenal adenosine and AMP rapidly increase glucose transport by intact small intestine |
Q40263729 | MAPKAPK-2 is a critical signaling intermediate in NHE3 activation following Na+-glucose cotransport. |
Q57364667 | Mechanisms of Ion Transport Regulation by Microfilaments |
Q35569905 | Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application |
Q85707925 | Molecular transport machinery involved in orchestrating luminal acid-induced duodenal bicarbonate secretion in vivo |
Q37485479 | NHE3 regulatory complexes |
Q64076170 | Neutrophil Cell Shape Change: Mechanism and Signalling during Cell Spreading and Phagocytosis |
Q38958544 | Phosphorylation of AKT induced by phosphorylated Hsp27 confers the apoptosis-resistance in t-AUCB-treated glioblastoma cells in vitro |
Q38720389 | Plasticity of the brush border - the yin and yang of intestinal homeostasis |
Q36848529 | Rapamycin Inhibition of mTOR Reduces Levels of the Na+/H+ Exchanger 3 in Intestines of Mice and Humans, Leading to Diarrhea |
Q37428401 | Regulation of expression of microvillus membrane proteins by estrogen in baboon fetal ovarian oocytes |
Q38141920 | Regulation of paracellular permeability: factors and mechanisms. |
Q34655805 | SGLT-1-mediated glucose uptake protects human intestinal epithelial cells against Giardia duodenalis-induced apoptosis. |
Q50501776 | Sgk-1 is a positive regulator of constitutive albumin uptake in renal proximal tubule cells. |
Q42518172 | Sodium and chloride absorptive defects in the small intestine in Slc26a6 null mice |
Q38605844 | Sodium status and the metabolic syndrome: a systematic review and meta-analysis of observational studies |
Q39628473 | Stimulation of TLRs by LMW-HA induces self-defense mechanisms in vaginal epithelium. |
Q52337636 | TGFβ and IGF1R signaling activate protein kinase A through differential regulation of ezrin phosphorylation in colon cancer cells. |
Q34720146 | Telencephalin protects PAJU cells from amyloid beta protein-induced apoptosis by activating the ezrin/radixin/moesin protein family/phosphatidylinositol-3-kinase/protein kinase B pathway |
Q35555968 | The ERM protein, ezrin, regulates neutrophil transmigration by modulating the apical localization of MRP2 in response to the SipA effector protein during Salmonella Typhimurium infection |
Q37297700 | The calcineurin homologous protein-1 increases Na(+)/H(+) -exchanger 3 trafficking via ezrin phosphorylation |
Q30572906 | WNK1-OSR1 kinase-mediated phospho-activation of Na+-K+-2Cl- cotransporter facilitates glioma migration |
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