TGF-β1 protects intestinal integrity and influences Smads and MAPK signal pathways in IPEC-J2 after TNF-α challenge

scientific article published on January 2017

TGF-β1 protects intestinal integrity and influences Smads and MAPK signal pathways in IPEC-J2 after TNF-α challenge is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1177/1753425917690815
P698PubMed publication ID28142299

P50authorShuting CaoQ123137142
P2093author name stringJianjun Lu
Caihong Hu
Lefei Jiao
Kan Xiao
Zehe Song
P2860cites workTumor Necrosis Factor Alpha Induces Neural Stem Cell Apoptosis Through Activating p38 MAPK Pathway.Q51569302
Zinc oxide influences mitogen-activated protein kinase and TGF-β1 signaling pathways, and enhances intestinal barrier integrity in weaned pigs.Q52650978
Whey protein concentrate enhances intestinal integrity and influences transforming growth factor-β1 and mitogen-activated protein kinase signalling pathways in piglets after lipopolysaccharide challenge.Q53800076
MAPK inhibitors differently modulate TGF-β/Smad signaling in HepG2 cells.Q54298655
Transforming Growth Factor-β, a Whey Protein Component, Strengthens the Intestinal Barrier by Upregulating Claudin-4 in HT-29/B6 CellsQ56972147
Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expressionQ24536188
Smad-dependent and Smad-independent pathways in TGF-beta family signallingQ28208250
Amelioration of IFN-γ and TNF-α-induced intestinal epithelial barrier dysfunction by berberine via suppression of MLCK-MLC phosphorylation signaling pathwayQ28487645
Proinflammatory cytokines tumor necrosis factor-alpha and interferon-gamma alter tight junction structure and function in the rat parotid gland Par-C10 cell lineQ28568696
Transforming growth factor beta1 ameliorates intestinal epithelial barrier disruption by Cryptosporidium parvum in vitro in the absence of mucosal T lymphocytesQ30306095
Mechanisms and modulation of intestinal epithelial repairQ32099554
Regulation of intestinal epithelial cell growth by transforming growth factor type betaQ33840554
Regulation of intestinal epithelial permeability by tight junctions.Q34287155
Tgf-beta induced Erk phosphorylation of smad linker region regulates smad signalingQ34374221
TGF-beta and the Smad signal transduction pathwayQ35003175
Developmental changes of TGF-β1 and Smads signaling pathway in intestinal adaption of weaned pigsQ35234945
Transforming growth factor-beta mediates intestinal healing and susceptibility to injury in vitro and in vivo through epithelial cellsQ35748961
Cytokines and the regulation of hypoxia-inducible factor (HIF)-1alphaQ36026149
Transforming Growth Factor-beta2 protects the small intestine during methotrexate treatment in rats possibly by reducing stem cell cyclingQ36624210
Negative regulation of TGF-beta receptor/Smad signal transduction.Q36743012
Restoration of barrier function in injured intestinal mucosaQ36788890
TNF-α enhances vascular cell adhesion molecule-1 expression in human bone marrow mesenchymal stem cells via the NF-κB, ERK and JNK signaling pathwaysQ37032444
Oral administration of transforming growth factor-β1 (TGF-β1) protects the immature gut from injury via Smad protein-dependent suppression of epithelial nuclear factor κB (NF-κB) signaling and proinflammatory cytokine productionQ37348970
The regulation of TGFbeta signal transductionQ37621155
Intestinal barrier function and absorption in pigs after weaning: a reviewQ37838009
The TGFbeta superfamily signaling pathwayQ38116934
Transforming growth factor-beta regulation of epithelial tight junction proteins enhances barrier function and blocks enterohemorrhagic Escherichia coli O157:H7-induced increased permeabilityQ38702390
Protective effects of Lactobacillus plantarum on epithelial barrier disruption caused by enterotoxigenic Escherichia coli in intestinal porcine epithelial cellsQ38782142
Homoharringtonine increases intestinal epithelial permeability by modulating specific claudin isoforms in Caco-2 cell monolayersQ38928151
Cytokines induce tight junction disassembly in airway cells via an EGFR-dependent MAPK/ERK1/2-pathwayQ39348423
TGFbeta stimulated re-epithelialisation is regulated by CTGF and Ras/MEK/ERK signallingQ40072195
Transforming growth factor-beta 1 inhibits non-pathogenic Gram negative bacteria-induced NF-kappa B recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylationQ40658888
Cross-talk between the p42/p44 MAP kinase and Smad pathways in transforming growth factor beta 1-induced furin gene transactivationQ40793124
Transforming growth factor beta s and wound healingQ41391410
Anemonin improves intestinal barrier restoration and influences TGF-β1 and EGFR signaling pathways in LPS-challenged pigletsQ42493267
Early weaning increases intestinal permeability, alters expression of cytokine and tight junction proteins, and activates mitogen-activated protein kinases in pigsQ44721245
TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activationQ44758263
Mitogen-activated protein kinases regulate COX-2 and mucosal recovery in ischemic-injured porcine ileumQ44858862
Role of ERK/mTOR signaling in TGFbeta-modulated focal adhesion kinase mRNA stability and protein synthesis in cultured rat IEC-6 intestinal epithelial cellsQ46064575
Tumour necrosis factor--induced loss of intestinal barrier function requires TNFR1 and TNFR2 signalling in a mouse model of total parenteral nutrition.Q50920142
P433issue3
P304page(s)276-284
P577publication date2017-01-01
P1433published inInnate ImmunityQ6035271
P1476titleTGF-β1 protects intestinal integrity and influences Smads and MAPK signal pathways in IPEC-J2 after TNF-α challenge
P478volume23

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cites work (P2860)
Q90448055Diosgenin inhibits the epithelial-mesenchymal transition initiation in osteosarcoma cells via the p38MAPK signaling pathway
Q52585912Effects of Lactobacillus reuteri LR1 on the growth performance, intestinal morphology and intestinal barrier function in weaned pigs.
Q47355932Sodium butyrate enhances intestinal integrity, inhibits mast cell activation, inflammatory mediator production and JNK signaling pathway in weaned pigs.

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