Adherens junction: molecular architecture and regulation

scientific article published on 05 August 2009

Adherens junction: molecular architecture and regulation is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1101/CSHPERSPECT.A002899
P8608Fatcat IDrelease_bj6t7vxw6jehlfhdizsjlcdady
P932PMC publication ID2882120
P698PubMed publication ID20457565
P5875ResearchGate publication ID44587435

P50authorMasatoshi TakeichiQ6144808
P2093author name stringWenxiang Meng
P2860cites workNectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing proteinQ22009475
Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherinsQ22254330
The SLUG zinc-finger protein represses E-cadherin in breast cancerQ24292674
EPLIN regulates actin dynamics by cross-linking and stabilizing filamentsQ24293766
Plakoglobin, or an 83-kD homologue distinct from beta-catenin, interacts with E-cadherin and N-cadherinQ24300513
A distinct PAR complex associates physically with VE-cadherin in vertebrate endothelial cellsQ24308075
Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contactsQ24319256
alpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cellsQ24322872
The uvomorulin-anchorage protein alpha catenin is a vinculin homologueQ24560521
The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different speciesQ24567493
Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly.Q24608988
Deconstructing the cadherin-catenin-actin complexQ24609677
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2Q24646996
MicroRNA-373 induces expression of genes with complementary promoter sequencesQ24652547
The desmosomeQ24656653
Association of p120, a tyrosine kinase substrate, with E-cadherin/catenin complexesQ24672732
Small dsRNAs induce transcriptional activation in human cellsQ24676787
Afadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junctionQ24678766
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasisQ28131703
Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of FrizzledQ28144517
Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary membersQ28145528
Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skinQ28203751
Prominent role of the Ig-like V domain in trans-interactions of nectins. Nectin3 and nectin 4 bind to the predicted C-C'-C"-D beta-strands of the nectin1 V domainQ28217548
Planar polarity from flies to vertebratesQ28239429
Junctional recruitment of mammalian Scribble relies on E-cadherin engagementQ28243180
E-cadherin mediated cell adhesion recruits SAP97 into the cortical cytoskeletonQ28265359
Structure and interactions of desmosomal and other cadherinsQ28277682
Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complexQ28289996
The 102 kd cadherin-associated protein: similarity to vinculin and posttranscriptional regulation of expressionQ28302135
Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cablesQ28507974
Two cell adhesion molecules, nectin and cadherin, interact through their cytoplasmic domain-associated proteinsQ28511190
Interneurite affinity is regulated by heterophilic nectin interactions in concert with the cadherin machineryQ28581846
Shroom regulates epithelial cell shape via the apical positioning of an actomyosin networkQ28590605
Stability of dendritic spines and synaptic contacts is controlled by alpha N-cateninQ28591625
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expressionQ28595042
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasionQ29616467
Junctional complexes in various epitheliaQ29620435
Solution structure of the epithelial cadherin domain responsible for selective cell adhesion.Q30193717
Paraxial protocadherin mediates cell sorting and tissue morphogenesis by regulating C-cadherin adhesion activityQ30441013
Feedback interactions between cell-cell adherens junctions and cytoskeletal dynamics in newt lung epithelial cellsQ30477543
Characterization of L-CAM, a major cell adhesion molecule from embryonic liver cellsQ37604054
Uvomorulin: a nonintegral membrane protein of early mouse embryoQ37617846
Intercellular junction assembly, dynamics, and homeostasisQ37698269
Planar cell polarity: keeping hairs straight is not so simpleQ37698284
A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions.Q38301815
The cadherins: cell-cell adhesion molecules controlling animal morphogenesisQ39525918
The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones.Q39758028
aPKC enables development of zonula adherens by antagonizing centripetal contraction of the circumferential actomyosin cablesQ39961185
Shroom3-mediated recruitment of Rho kinases to the apical cell junctions regulates epithelial and neuroepithelial planar remodelingQ40002667
Involvement of p120 carboxy-terminal domain in cadherin traffickingQ40030967
A dileucine motif in its cytoplasmic domain directs beta-catenin-uncoupled E-cadherin to the lysosomeQ40040686
Studies on tumors produced by cells transformed with herpes simplex virus type 2Q40117727
Basal-to-apical cadherin flow at cell junctionsQ40198145
Dynamic microtubules regulate the local concentration of E-cadherin at cell-cell contactsQ40293778
Type II cadherin ectodomain structures: implications for classical cadherin specificity.Q40300083
Regulation of E-cadherin endocytosis by nectin through afadin, Rap1, and p120ctnQ40429873
Separation force measurements reveal different types of modulation of E-cadherin-based adhesion by nectin-1 and -3.Q40490358
A novel interaction between kinesin and p120 modulates p120 localization and functionQ40607309
p120 catenin associates with microtubules: inverse relationship between microtubule binding and Rho GTPase regulationQ40609842
Role of each immunoglobulin-like loop of nectin for its cell-cell adhesion activityQ40669794
Quick-freeze, deep-etch visualization of the cytoskeleton beneath surface differentiations of intestinal epithelial cellsQ41367370
Ultrastructure of the zonula adherens revealed by rapid-freeze deep-etchingQ41631054
Molecular organization of the uvomorulin-catenin complexQ41640629
PAR3 acts as a molecular organizer to define the apical domain of chick neuroepithelial cellsQ42501863
Endocytosis of junctional cadherins in bovine kidney epithelial (MDBK) cells cultured in low Ca2+ ion mediumQ43107902
Dynein binds to beta-catenin and may tether microtubules at adherens junctions.Q43754950
Regulation of p120-catenin nucleocytoplasmic shuttling activityQ44571728
Shroom induces apical constriction and is required for hingepoint formation during neural tube closureQ46093822
Axon patterning requires DN-cadherin, a novel neuronal adhesion receptor, in the Drosophila embryonic CNS.Q47070236
A Drosophila homolog of cadherin associated with armadillo and essential for embryonic cell-cell adhesionQ47070459
Drosophila exocyst components Sec5, Sec6, and Sec15 regulate DE-Cadherin trafficking from recycling endosomes to the plasma membraneQ47070861
Patterned gene expression directs bipolar planar polarity in DrosophilaQ47071305
Myosin-dependent junction remodelling controls planar cell intercalation and axis elongationQ47363099
Diversification of epithelial adherens junctions with independent reductive changes in cadherin form: identification of potential molecular synapomorphies among bilateriansQ48120261
Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortexQ48601032
Multicellular rosette formation links planar cell polarity to tissue morphogenesis.Q50713462
The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin.Q52450397
Drosophila Cip4 and WASp define a branch of the Cdc42-Par6-aPKC pathway regulating E-cadherin endocytosis.Q52590050
Apicobasal polarity complexes.Q52662344
A two-tiered mechanism for stabilization and immobilization of E-cadherin.Q52691482
Two different mechanisms of planar cell intercalation leading to tissue elongation.Q52692294
Cdc42, Par6, and aPKC regulate Arp2/3-mediated endocytosis to control local adherens junction stability.Q52695072
aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarizationQ58323641
Expressed recombinant cadherins mediate cell sorting in model systemsQ68502688
Teratocarcinoma cell adhesion: identification of a cell-surface protein involved in calcium-dependent cell aggregationQ70283012
Molecular nature of the calcium-dependent cell-cell adhesion system in mouse teratocarcinoma and embryonic cells studied with a monoclonal antibodyQ71259159
Conformational changes of the recombinant extracellular domain of E-cadherin upon calcium bindingQ72119026
p120-catenin regulates microtubule dynamics and cell migration in a cadherin-independent mannerQ80511584
Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctionsQ30479975
Contact-dependent promotion of cell migration by the OL-protocadherin-Nap1 interactionQ30482817
p120, a novel substrate of protein tyrosine kinase receptors and of p60v-src, is related to cadherin-binding factors beta-catenin, plakoglobin and armadilloQ30799593
Microtubules regulate disassembly of epithelial apical junctionsQ30809823
Nature and anisotropy of cortical forces orienting Drosophila tissue morphogenesisQ33382061
New mode of DNA binding of multi-zinc finger transcription factors: deltaEF1 family members bind with two hands to two target sitesQ33891247
A 135-kd membrane protein of intercellular adherens junctionsQ33939926
Epithelial cell shape: cadherins and small GTPasesQ34084674
Nectins and nectin-like molecules: roles in cell adhesion, migration, and polarization.Q34220056
The cadherin superfamily in neuronal connections and interactionsQ34572868
PALS1 regulates E-cadherin trafficking in mammalian epithelial cellsQ35650728
Cell adhesion receptors in C. elegansQ35748298
Roles of nectins in cell adhesion, migration and polarization.Q35954748
Mechanism of recruiting Sec6/8 (exocyst) complex to the apical junctional complex during polarization of epithelial cellsQ36012274
The p120 family of cell adhesion moleculesQ36093195
Cadherin dimers in cell-cell adhesionQ36093208
New insights into Fat cadherinsQ36143760
Organising cells into tissues: new roles for cell adhesion molecules in planar cell polarityQ36229084
delta-Protocadherins: unique structures and functionsQ36302383
Long-range coordination of planar polarity in DrosophilaQ36318302
The positioning and segregation of apical cues during epithelial polarity establishment in DrosophilaQ36320620
p120 catenin associates with kinesin and facilitates the transport of cadherin-catenin complexes to intercellular junctionsQ36324842
EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin beltQ36423364
p120-catenin: Past and presentQ36686745
Rap1: a key regulator in cell-cell junction formationQ36689667
Cell-to-cell adherens junction formation and actin filament organization: similarities and differences between non-polarized fibroblasts and polarized epithelial cellsQ36702584
Cell surface mechanics and the control of cell shape, tissue patterns and morphogenesis.Q36887551
Protocadherin family: diversity, structure, and functionQ36971276
Desmosomal glycoproteins I, II and III: novel members of the cadherin superfamilyQ36974780
Structure and function of desmosomesQ36983434
Resolving cadherin interactions and binding cooperativity at the single-molecule levelQ37068292
MicroRNAs as regulators of epithelial-mesenchymal transition.Q37300965
Adhesive and signaling functions of cadherins and catenins in vertebrate development.Q37412685
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)a002899
P577publication date2009-08-05
P1433published inCold Spring Harbor Perspectives in BiologyQ3927509
P1476titleAdherens junction: molecular architecture and regulation
P478volume1

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Q58612503The role of microtubules in the regulation of epithelial junctions
Q36499221The status of intercellular junctions in established lens epithelial cell lines.
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