p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice

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p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI41414
P932PMC publication ID2877948
P698PubMed publication ID20484816
P5875ResearchGate publication ID44613595

P2093author name stringRobert J Coffey
M Kay Washington
Albert B Reynolds
Andrey Efimov
Deborah L Gumucio
Michael A Davis
Patrick E Burnett
Sarah P Short
Whitney G Smalley-Freed
P2860cites workThe catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factorQ22009416
The uvomorulin-anchorage protein alpha catenin is a vinculin homologueQ24560521
E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancersQ24597264
The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressorQ24601117
p120-catenin mediates inflammatory responses in the skinQ24647606
p120 catenin regulates dendritic spine and synapse development through Rho-family GTPases and cadherinsQ24654118
The development of animal models for the study of necrotizing enterocolitisQ24657576
A core function for p120-catenin in cadherin turnoverQ24672238
Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cellsQ24672311
A novel role for p120 catenin in E-cadherin functionQ24674430
The E-cadherin-catenin complex in tumour metastasis: structure, function and regulationQ28144549
The catenin p120ctn inhibits Kaiso-mediated transcriptional repression of the beta-catenin/TCF target gene matrilysinQ28244021
Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complexQ28289996
Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-cateninQ28293223
THE DEVELOPMENT OF THE BACTERIAL FLORA IN THE GASTROINTESTINAL TRACT OF MICE.Q42830078
Immunohistochemical evaluation of E-cadherin adhesion molecule expression in human gastric cancerQ45162134
Regulation of stromal cell cyclooxygenase-2 in the ApcMin/+ mouse model of intestinal tumorigenesisQ46747962
Inflammatory bowel disease: etiology and pathogenesisQ47899867
Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine.Q52118607
Mechanism of extracellular domain-deleted dominant negative cadherins.Q52177758
Colonic expression of leukotriene-pathway enzymes in inflammatory bowel diseases.Q53576664
Expression of a dominant negative cadherin mutant inhibits proliferation and stimulates terminal differentiation of human epidermal keratinocytesQ57385103
Forced expression of E-cadherin in the mouse intestinal epithelium slows cell migration and provides evidence for nonautonomous regulation of cell fate in a self-renewing systemQ71019227
The morphogenetic role of cadherin cell adhesion molecules in human cancer: a thematic reviewQ74553287
Expression of catenins and E-cadherin during epithelial restitution in inflammatory bowel diseaseQ77600680
Colonic neutrophils in inflammatory bowel disease: double-edged swords of the innate immune system with protective and destructive capacityQ80135270
Mouse models of inflammatory bowel diseaseQ81158539
Dietary fatty acids modulate chronic colitis, colitis-associated colon neoplasia and COX-2 expression in IL-10 knockout miceQ82658352
Regulation of cadherin stability and turnover by p120ctn: implications in disease and cancerQ28294841
The 102 kd cadherin-associated protein: similarity to vinculin and posttranscriptional regulation of expressionQ28302135
Blocked acinar development, E-cadherin reduction, and intraepithelial neoplasia upon ablation of p120-catenin in the mouse salivary glandQ28508350
Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestineQ28510081
Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)Q28586461
Unravelling the pathogenesis of inflammatory bowel diseaseQ29547551
Morphogenetic roles of classic cadherinsQ29614941
Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influencesQ29617565
The primary defect in experimental ileitis originates from a nonhematopoietic sourceQ30439653
The c-jun kinase/stress-activated pathway: regulation, function and role in human diseaseQ30500831
Role of tumor necrosis factor receptor 2 (TNFR2) in colonic epithelial hyperplasia and chronic intestinal inflammation in miceQ30793383
p120 catenin regulates the actin cytoskeleton via Rho family GTPasesQ33180846
Dancing in and out of the nucleus: p120(ctn) and the transcription factor KaisoQ33260805
Diverse functions of JNK signaling and c-Jun in stress response and apoptosisQ33771779
PDGF receptor activation induces p120-catenin phosphorylation at serine 879 via a PKCalpha-dependent pathwayQ34077566
Neutrophil migration across a cultured intestinal epithelium. Dependence on a CD11b/CD18-mediated event and enhanced efficiency in physiological directionQ34209118
Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherinQ34290465
E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain.Q34408492
Ezrin...a metastatic detERMinant?Q35681312
Neutrophil transmigration in inflammatory bowel disease is associated with differential expression of epithelial intercellular junction proteinsQ35747165
Cyclooxygenase-2 and its role in colorectal cancer developmentQ35876124
JAM-A regulates permeability and inflammation in the intestine in vivoQ36294373
In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell deathQ36382475
Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitisQ36404110
Molecular pathogenesis of inflammatory bowel disease: genotypes, phenotypes and personalized medicineQ36801108
Loss of p120 catenin and links to mitotic alterations, inflammation, and skin cancerQ36899976
Necrotizing enterocolitis: recent scientific advances in pathophysiology and preventionQ37112080
Disassembly of endothelial and epithelial junctions during leukocyte transmigrationQ37175756
Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targetsQ38514045
Inhibition of RhoA by p120 cateninQ38525924
Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell linesQ39939604
p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho.Q40203974
Tumor necrosis factor regulates intestinal epithelial cell migration by receptor-dependent mechanismsQ40685684
Neutrophil transepithelial migration: evidence for sequential, contact-dependent signaling events and enhanced paracellular permeability independent of transjunctional migrationQ40723237
p120 catenin affects cell motility via modulation of activity of Rho-family GTPases: a link between cell-cell contact formation and regulation of cell locomotion.Q40828213
Cadherin function in junctional complex rearrangement and posttranslational control of cadherin expression.Q40974633
Developmental regulation of villin gene expression in the epithelial cell lineages of mouse digestive and urogenital tractsQ41114035
Characterization of prostaglandin E2 generation through the cyclooxygenase (COX)-2 pathway in human neutrophilsQ41446246
The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathwaysQ41823904
Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumorsQ42544853
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1824-1835
P577publication date2010-05-17
P1433published inJournal of Clinical InvestigationQ3186904
P1476titlep120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice
P478volume120

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