High-affinity receptors for peptides of the bombesin family in Swiss 3T3 cells

scientific article published in November 1985

High-affinity receptors for peptides of the bombesin family in Swiss 3T3 cells is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1985PNAS...82.7616Z
P356DOI10.1073/PNAS.82.22.7616
P932PMC publication ID391384
P698PubMed publication ID2999772
P5875ResearchGate publication ID20156051

P2093author name stringRozengurt E
Zachary I
P2860cites workQuantitative studies of the growth of mouse embryo cells in culture and their development into established linesQ24683034
Gastrin releasing peptide is a selective mitogen for small cell lung carcinoma in vitroQ34525039
Characterization of a gastrin releasing peptide from porcine non-antral gastric tissueQ34700990
Isolation and structure of bombesin and alytesin, two analogous active peptides from the skin of the european amphibiansBombina andAlytesQ34704232
Neuromedin B: a novel bombesin-like peptide identified in porcine spinal cordQ34713800
An 18,000 molecular weight polypeptide induces early events and stimulates DNA synthesis in cultured cellsQ35043287
Membrane receptors for hormones and neurotransmittersQ36198388
Bombesin stimulates insulin secretion by a pancreatic islet cell lineQ36255932
Human lung small-cell carcinoma contains bombesinQ36290461
Brain regulation of gastric secretion: influence of neuropeptidesQ36407482
Vasopressin stimulation of mouse 3T3 cell growthQ37320858
Phorbol esters, phospholipase C, and growth factors rapidly stimulate the phosphorylation of a Mr 80,000 protein in intact quiescent 3T3 cellsQ37509292
Interaction of bombesin and litorin with specific membrane receptors on pancreatic acinar cellsQ37596920
A substance P antagonist inhibits vagally induced increase in vascular permeability and bronchial smooth muscle contraction in the guinea pig.Q37604303
Bombesin stimulation of DNA synthesis and cell division in cultures of Swiss 3T3 cellsQ37611834
Hormonal regulation of peptide receptors and target cell responsesQ38074649
The platelet-derived growth factorQ39739322
Autocrine growth factors and cancerQ39815279
Localization of regulatory peptides in the gut.Q40088709
Stimulation of DNA Synthesis in Quiescent Cultured Cells: Exogenous Agents, Internal Signals, and Early EventsQ40122560
Molecular aspects of growth factor action: Receptors and intracellular signalsQ40168460
Neuronal peptides in the intestineQ40248563
Stimulation of DNA synthesis by tumour promoter and pure mitogenic factorsQ40699360
Bombesin-like immunoreactivity in the lungQ40902841
Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancerQ41362569
Serum, like phorbol esters, rapidly activates protein kinase C in intact quiescent fibroblastsQ41378028
Bombesin-like peptides in mammalsQ41681598
Chemical messengers: a view from the gutQ41681614
Characterization of bombesin receptors in a rat pituitary cell lineQ41921197
Platelet-derived growth factor elicits cyclic AMP accumulation in swiss 3T3 cells: Role of prostaglandin productionQ42822965
Inhibition of epidermal growth factor binding to mouse cultured cells by fibroblast-derived growth factor. Evidence for an indirect mechanismQ42825575
Phorbol esters and vasopressin stimulate DNA synthesis by a common mechanismQ42827980
A synthetic peptide that is a bombesin receptor antagonistQ46175289
Neuromedin B is a major bombesin-like peptide in rat brain: regional distribution of neuromedin B and neuromedin C in rat brain, pituitary and spinal cordQ48601906
Growth factors, cell proliferation and cancer: an overview.Q53559020
Regulatory Peptides in the Mammalian Respiratory Tract*Q53932202
Bombesin suppresses feeding in ratsQ58881342
Bombesin-like peptides in rat brain: Quantitation and biochemical characterizationQ66955057
Bombesin, bombesin analogues, and related peptides: effects on thermoregulationQ67338909
Gastrin-releasing peptide immunoreactivity in medullary thyroid carcinomaQ70337842
Similarities between fibroblast-derived growth factor and platelet-derived growth factorQ70556227
Bombesin and the C-terminal tetradecapeptide of gastrin-releasing peptide are growth factors for normal human bronchial epithelial cellsQ70813711
Gastrin-releasing peptide-related peptides in a human malignant lung carcinoid tumorQ71030228
Bombesin, somatostatin and neurotensin-like immunoreactivity in bronchial carcinomaQ72504496
High Levels of Intracellular Bombesin Characterize Human Small-Cell Lung CarcinomaQ72913351
P433issue22
P407language of work or nameEnglishQ1860
P304page(s)7616-7620
P577publication date1985-11-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleHigh-affinity receptors for peptides of the bombesin family in Swiss 3T3 cells
P478volume82

Reverse relations

cites work (P2860)
Q41338454A tyrosine protein kinase activated by bombesin in normal fibroblasts and small cell carcinomas.
Q28581445Activation of neuromedin B-preferring bombesin receptors on rat glioblastoma C-6 cells increases cellular Ca2+ and phosphoinositides
Q33563141Activation of the protein-tyrosine kinase associated with the bombesin receptor complex in small cell lung carcinomas
Q41870097Bombesin and bombesin antagonists: studies in Swiss 3T3 cells and human small cell lung cancer
Q42799849Bombesin and platelet-derived growth factor stimulate formation of inositol phosphates and Ca2+ mobilization in Swiss 3T3 cells by different mechanisms
Q41714258Bombesin receptor from Swiss 3T3 cells. Affinity chromatography and reconstitution into phospholipid vesicles
Q41812705Bombesin receptor in membranes from Swiss 3T3 cells. Binding characteristics, affinity labelling and modulation by guanine nucleotides
Q41044012Bombesin stimulates cholecystokinin secretion through mitogen-activated protein-kinase-dependent and -independent mechanisms in the enteroendocrine STC-1 cell line
Q37518178Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation in intact Swiss 3T3 cells
Q42805738Bombesin-induction of cell proliferation in 3T3 cells. Specific receptors and early signaling events
Q41688512Bombesin-like peptides induce Ca2(+)-activated K+ conductance increases in mouse fibroblasts
Q42832573Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin
Q42001424C-terminal bombesin sequence requirements for binding and effects on protein synthesis in Swiss 3T3 cells
Q42822840CCK(B)/gastrin receptor mediates synergistic stimulation of DNA synthesis and cyclin D1, D3, and E expression in Swiss 3T3 cells
Q34339086Ca2+-mobilizing actions of platelet-derived growth factor differ from those of bombesin and vasopressin in Swiss 3T3 mouse cells
Q41456961Characterization of high-affinity receptors for bombesin/gastrin releasing peptide on the human prostate cancer cell lines PC-3 and DU-145: internalization of receptor bound 125I-(Tyr4) bombesin by tumor cells
Q41886809Characterization of ligand binding and processing by bombesin receptors in an insulin-secreting cell line
Q41651385Characterization of ligand binding and processing by gastrin-releasing peptide receptors in a small-cell lung cancer cell line
Q42803904Characterization of the high-affinity receptors on Swiss 3T3 cells which mediate the binding, internalization and degradation of the mitogenic peptide bombesin
Q36140580Development of potent gastrin-releasing peptide antagonists having a D-Pro-psi(CH2NH)-Phe-NH2 C terminus
Q41507698Early events elicited by bombesin and structurally related peptides in quiescent Swiss 3T3 cells. I. Activation of protein kinase C and inhibition of epidermal growth factor binding
Q41507845Early events elicited by bombesin and structurally related peptides in quiescent Swiss 3T3 cells. II. Changes in Na+ and Ca2+ fluxes, Na+/K+ pump activity, and intracellular pH
Q33880714Early phosphorylation events following the treatment of Swiss 3T3 cells with bombesin and the mammalian bombesin-related peptide, gastrin-releasing peptide
Q42488731Effects of the amphiphilic peptides mastoparan and adenoregulin on receptor binding, G proteins, phosphoinositide breakdown, cyclic AMP generation, and calcium influx
Q42799298Endothelin potentiates growth factor-stimulated DNA synthesis in Swiss 3T3 cells
Q36492513Function of non-visual arrestins in signaling and endocytosis of the gastrin-releasing peptide receptor (GRP receptor).
Q33853110Heterologous desensitization of bombesin-induced mitogenesis by prolonged exposure to vasopressin: a post-receptor signal transduction block
Q68257969High-affinity binding sites for bombesin on mouse colonic mucosal membranes
Q42830245Homodimeric forms of bombesin act as potent antagonists of bombesin on Swiss 3T3 cells
Q24295485Human gastrin-releasing peptide gene maps to chromosome band 18q21
Q38199949Interaction of bombesin and related peptides with receptors on pancreatic acinar cells
Q41347070Internalization and degradation of peptides of the bombesin family in Swiss 3T3 cells occurs without ligand-induced receptor down-regulation.
Q68244166Isolation of a gastrin releasing peptide receptor from normal rat pancreas
Q45191613Isolation of the bombesin/gastrin-releasing peptide receptor from human small cell lung carcinoma NCI-H345 cells
Q42502622Modulation of bombesin-induced phosphatidylinositol hydrolysis in a small-cell lung-cancer cell line
Q35606961Modulation of cisplatin sensitivity and growth rate of an ovarian carcinoma cell line by bombesin and tumor necrosis factor-alpha
Q29465546Molecular cloning of the bombesin/gastrin-releasing peptide receptor from Swiss 3T3 cells
Q28145780Neuromedin B
Q48142280Neuromedin B and neuromedin Ca. Two mammalian bombesin-like peptides identified in porcine spinal cord and brain
Q37664018Neuropeptide growth factors and cancer
Q39242005Neuropeptide-induced cytosolic Ca2+ transients and phosphatidylinositol turnover in cultured human retinal pigment ephithelial cells
Q36396935Neuropeptides as cellular growth factors: role of multiple signalling pathways
Q36253648New perspectives in lung cancer. 2. Growth factors and lung cancer
Q42810686Normal p21N-ras couples bombesin and other growth factor receptors to inositol phosphate production
Q39505491Oncogene amplification in tumor cells.
Q35996967Potent bombesin antagonists with C-terminal Leu-psi(CH2-N)-Tac-NH2 or its derivatives
Q42007482Protein kinase C-mediated negative-feedback inhibition of unstimulated and bombesin-stimulated polyphosphoinositide hydrolysis in Swiss-mouse 3T3 cells
Q42136685Protein kinase D mediates mitogenic signaling by Gq-coupled receptors through protein kinase C-independent regulation of activation loop Ser744 and Ser748 phosphorylation.
Q42826316Protein kinase D potentiates DNA synthesis and cell proliferation induced by bombesin, vasopressin, or phorbol esters in Swiss 3T3 cells
Q38707749Protein kinase D1 (PKD1) phosphorylation on Ser203 by type I p21-activated kinase (PAK) regulates PKD1 localization.
Q40360063Qdot nanocrystal conjugates conjugated to bombesin or ANG II label the cognate G protein-coupled receptor in living cells
Q42242739Rapid desensitization and resensitization of bombesin-stimulated phospholipase D activity in Swiss 3T3 cells
Q36902393Receptor for bombesin with associated tyrosine kinase activity.
Q41524291Receptor-activated currents in mouse fibroblasts expressing transfected bombesin receptor subtype cDNAs
Q41999344Regulation of bombesin-stimulated inositol 1,4,5-trisphosphate generation in Swiss 3T3 fibroblasts by a guanine-nucleotide-binding protein
Q39226415Role of inositol trisphosphate as a second messenger in signal transduction processes: an essay
Q48368067Solubilization and purification of bombesin/gastrin releasing peptide receptors from human cell lines
Q42832747Solubilization of the bombesin receptor from Swiss 3T3 cell membranes. Functional association to a guanine nucleotide regulatory protein
Q42825119Stimulation of tyrosine kinase activity in anti-phosphotyrosine immune complexes of Swiss 3T3 cell lysates occurs rapidly after addition of bombesin, vasopressin, and endothelin to intact cells
Q72092878Substance P: A competence factor for human fibroblast proliferation that induces the release of growth‐regulatory arachidonic acid metabolites
Q41106807Temporal relationship between inositol polyphosphate formation and increases in cytosolic Ca2+ in quiescent 3T3 cells stimulated by platelet-derived growth factor, bombesin and vasopressin.
Q42087694The roles of multiple pathways in regulating bombesin-stimulated phospholipase D activity in Swiss 3T3 fibroblasts
Q42805845Two classes of antagonist interact with receptors for the mitogenic neuropeptides bombesin, bradykinin, and vasopressin
Q42809742Tyrphostin inhibits bombesin stimulation of tyrosine phosphorylation, c-fos expression, and DNA synthesis in Swiss 3T3 cells
Q33560104[D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, a potent bombesin antagonist in murine Swiss 3T3 cells, inhibits the growth of human small cell lung cancer cells in vitro
Q42807084[D-Arg1,D-Trp5,7,9,Leu11]Substance P coordinately and reversibly inhibits bombesin- and vasopressin-induced signal transduction pathways in Swiss 3T3 cells

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