scholarly article | Q13442814 |
P50 | author | Richard T Waldron | Q62566637 |
P2093 | author name string | Enrique Rozengurt | |
James Sinnett-Smith | |||
Rodrigo Jacamo | |||
Osvaldo Rey | |||
Robert Kui | |||
Steven H Young | |||
Yunzu M Wang | |||
P2860 | cites work | Signal transduction pathways in the mitogenic response to G protein-coupled neuropeptide receptor agonists | Q22009085 |
Protein kinase D regulates the fission of cell surface destined transport carriers from the trans-Golgi network | Q24290905 | ||
Protein kinase D2 mediates lysophosphatidic acid-induced interleukin 8 production in nontransformed human colonic epithelial cells through NF-kappaB | Q24300560 | ||
Protein kinase D2 mediates activation of nuclear factor kappaB by Bcr-Abl in Bcr-Abl+ human myeloid leukemia cells | Q24323078 | ||
Protein kinase D mediates a stress-induced NF-kappaB activation and survival pathway | Q24337864 | ||
The RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins. | Q24537123 | ||
Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK | Q28259117 | ||
Regulation and interaction of pp90(rsk) isoforms with mitogen-activated protein kinases | Q28298000 | ||
The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C | Q28327651 | ||
Protein kinase D2 potentiates MEK/ERK/RSK signaling, c-Fos accumulation and DNA synthesis induced by bombesin in Swiss 3T3 cells | Q28594706 | ||
Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction. | Q33690319 | ||
Intramolecular interaction between phosphorylated tyrosine-783 and the C-terminal Src homology 2 domain activates phospholipase C-gamma1. | Q33934437 | ||
Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission | Q34226003 | ||
Neuropeptides as growth factors for normal and cancerous cells | Q34563386 | ||
Protein kinase C activation potently down-regulates the expression of its major substrate, 80K, in Swiss 3T3 cells | Q35929386 | ||
Protein kinase D signaling | Q36035199 | ||
Gö 6983: a fast acting protein kinase C inhibitor that attenuates myocardial ischemia/reperfusion injury | Q36298383 | ||
Sequential protein kinase C (PKC)-dependent and PKC-independent protein kinase D catalytic activation via Gq-coupled receptors: differential regulation of activation loop Ser(744) and Ser(748) phosphorylation | Q36741576 | ||
Mitogenic signaling pathways induced by G protein-coupled receptors | Q36929839 | ||
Phorbol esters, phospholipase C, and growth factors rapidly stimulate the phosphorylation of a Mr 80,000 protein in intact quiescent 3T3 cells | Q37509292 | ||
High-affinity receptors for peptides of the bombesin family in Swiss 3T3 cells | Q37554881 | ||
Early signals in the mitogenic response | Q39504519 | ||
Dissociation of mitogen-activated protein kinase activation from p125 focal adhesion kinase tyrosine phosphorylation in Swiss 3T3 cells stimulated by bombesin, lysophosphatidic acid, and platelet-derived growth factor | Q40243116 | ||
Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes | Q40322638 | ||
Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion | Q40612668 | ||
Tyrosine kinase inhibition: an approach to drug development | Q40613606 | ||
Neurotensin induces protein kinase C-dependent protein kinase D activation and DNA synthesis in human pancreatic carcinoma cell line PANC-1. | Q40742637 | ||
Vasopressin-mediated mitogenic signaling in intestinal epithelial cells | Q40752381 | ||
Protein kinase C (PKC)eta-mediated PKC mu activation modulates ERK and JNK signal pathways | Q40763883 | ||
EGF receptor function is required in late G(1) for cell cycle progression induced by bombesin and bradykinin | Q40786481 | ||
Activation loop Ser744 and Ser748 in protein kinase D are transphosphorylated in vivo. | Q40798561 | ||
PKD in intestinal epithelial cells: rapid activation by phorbol esters, LPA, and angiotensin through PKC. | Q40821330 | ||
Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate | Q41035564 | ||
Protein kinase D (PKD) activation in intact cells through a protein kinase C-dependent signal transduction pathway. | Q41078558 | ||
Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes | Q41173469 | ||
Expression and characterization of PKD, a phorbol ester and diacylglycerol-stimulated serine protein kinase. | Q41379386 | ||
Activation of protein kinase D by signaling through the alpha subunit of the heterotrimeric G protein G(q). | Q41714408 | ||
Lysophosphatidic acid rapidly induces protein kinase D activation through a pertussis toxin-sensitive pathway | Q41715660 | ||
Activation of protein kinase C subtypes alpha, gamma, delta, epsilon, zeta, and eta by tumor-promoting and nontumor-promoting agents | Q42062593 | ||
Protein kinase D activation by mutations within its pleckstrin homology domain. | Q42448861 | ||
Identification of in vivo phosphorylation sites required for protein kinase D activation. | Q42462150 | ||
Protein kinase D activation by deletion of its cysteine-rich motifs | Q42475083 | ||
Activation of protein kinase D by signaling through Rho and the alpha subunit of the heterotrimeric G protein G13. | Q42508695 | ||
Tyrosine kinase inhibitors. 8. An unusually steep structure-activity relationship for analogues of 4-(3-bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a potent inhibitor of the epidermal growth factor receptor | Q42557425 | ||
Bombesin, vasopressin, endothelin, bradykinin, and platelet-derived growth factor rapidly activate protein kinase D through a protein kinase C-dependent signal transduction pathway. | Q42795887 | ||
Bryostatin 1 induces biphasic activation of protein kinase D in intact cells | Q42797815 | ||
Bombesin, lysophosphatidic acid, and epidermal growth factor rapidly stimulate focal adhesion kinase phosphorylation at Ser-910: requirement for ERK activation | Q42803219 | ||
Bombesin stimulation of p125 focal adhesion kinase tyrosine phosphorylation. Role of protein kinase C, Ca2+ mobilization, and the actin cytoskeleton. | Q42808194 | ||
Identification of a receptor for peptides of the bombesin family in Swiss 3T3 cells by affinity cross-linking | Q42808474 | ||
The expression of 80K/MARCKS, a major substrate of protein kinase C (PKC), is down-regulated through both PKC-dependent and -independent pathways. Effects of bombesin, platelet-derived growth factor, and cAMP | Q42818091 | ||
CCK(B)/gastrin receptor mediates synergistic stimulation of DNA synthesis and cyclin D1, D3, and E expression in Swiss 3T3 cells | Q42822840 | ||
Protein kinase D potentiates DNA synthesis and cell proliferation induced by bombesin, vasopressin, or phorbol esters in Swiss 3T3 cells | Q42826316 | ||
G protein-coupled receptor-mediated phosphorylation of the activation loop of protein kinase D: dependence on plasma membrane translocation and protein kinase Cepsilon | Q42828192 | ||
Protein kinase D potentiates DNA synthesis induced by Gq-coupled receptors by increasing the duration of ERK signaling in swiss 3T3 cells | Q42831514 | ||
Protein kinase D-mediated anterograde membrane trafficking is required for fibroblast motility | Q42832109 | ||
Protein kinase C phosphorylates protein kinase D activation loop Ser744 and Ser748 and releases autoinhibition by the pleckstrin homology domain. | Q44198663 | ||
Cooperation of Gq, Gi, and G12/13 in protein kinase D activation and phosphorylation induced by lysophosphatidic acid | Q44246034 | ||
CCK2 (CCK(B)/gastrin) receptor mediates rapid protein kinase D (PKD) activation through a protein kinase C-dependent pathway | Q46279700 | ||
Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/Protein kinase Cmu | Q78208164 | ||
P433 | issue | 20 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phosphorylation | Q242736 |
P304 | page(s) | 13434-13445 | |
P577 | publication date | 2009-03-16 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Protein kinase D mediates mitogenic signaling by Gq-coupled receptors through protein kinase C-independent regulation of activation loop Ser744 and Ser748 phosphorylation | |
P478 | volume | 284 |
Q92576734 | A ubiquitin-like domain controls protein kinase D dimerization and activation by trans-autophosphorylation |
Q37706498 | Androgen suppresses protein kinase D1 expression through fibroblast growth factor receptor substrate 2 in prostate cancer cells |
Q38760403 | Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD). |
Q33615492 | CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway |
Q35895710 | Cholinergic signaling inhibits oxalate transport by human intestinal T84 cells |
Q39645306 | Chronic regulation of colonic epithelial secretory function by activation of G protein-coupled receptors |
Q33820455 | Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer |
Q30428751 | Design, Synthesis, and Biological Evaluation of PKD Inhibitors |
Q35778013 | Differential PKC-dependent and -independent PKD activation by G protein α subunits of the Gq family: selective stimulation of PKD Ser⁷⁴⁸ autophosphorylation by Gαq. |
Q41489966 | Discovery of a potent protein kinase D inhibitor: insights in the binding mode of pyrazolo[3,4-d]pyrimidine analogues. |
Q37417683 | Dynamic kisspeptin receptor trafficking modulates kisspeptin-mediated calcium signaling |
Q37601331 | Emergency Spatiotemporal Shift: The Response of Protein Kinase D to Stress Signals in the Cardiovascular System |
Q37050910 | Extracellular nucleotides inhibit oxalate transport by human intestinal Caco-2-BBe cells through PKC-δ activation |
Q36494649 | Histamine induces activation of protein kinase D that mediates tissue factor expression and activity in human aortic smooth muscle cells. |
Q33923820 | Induced overexpression of protein kinase D1 stimulates mitogenic signaling in human pancreatic carcinoma PANC-1 cells |
Q36084010 | Inducible silencing of protein kinase D3 inhibits secretion of tumor-promoting factors in prostate cancer |
Q28081153 | Insights into bombesin receptors and ligands: Highlighting recent advances |
Q46471150 | KRAS, YAP, and obesity in pancreatic cancer: A signaling network with multiple loops |
Q34438891 | Novel function of cardiac protein kinase D1 as a dynamic regulator of Ca2+ sensitivity of contraction |
Q30524184 | PKCβII modulation of myocyte contractile performance |
Q34988846 | PKD1 mediates negative feedback of PI3K/Akt activation in response to G protein-coupled receptors |
Q39646301 | PKD2 mediates multi-drug resistance in breast cancer cells through modulation of P-glycoprotein expression |
Q36775710 | Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552 |
Q34452638 | Protein Kinase D1 Mediates Stimulation of DNA Synthesis and Proliferation in Intestinal Epithelial IEC-18 Cells and in Mouse Intestinal Crypts |
Q28505832 | Protein kinase D is implicated in the reversible commitment to differentiation in primary cultures of mouse keratinocytes |
Q34675735 | Protein kinase D isoforms are activated in an agonist-specific manner in cardiomyocytes |
Q35097285 | Protein kinase D orchestrates the activation of DRAK2 in response to TCR-induced Ca2+ influx and mitochondrial reactive oxygen generation |
Q39348454 | Protein kinase D signaling in cancer: A friend or foe? |
Q35239280 | Protein kinase D signaling: multiple biological functions in health and disease |
Q39540024 | Protein kinase D-dependent CXCR4 down-regulation upon BCR triggering is linked to lymphadenopathy in chronic lymphocytic leukaemia |
Q38707749 | Protein kinase D1 (PKD1) phosphorylation on Ser203 by type I p21-activated kinase (PAK) regulates PKD1 localization. |
Q33626512 | Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signaling |
Q35138462 | Protein kinase D: coupling extracellular stimuli to the regulation of cell physiology |
Q36175932 | Rapid protein kinase D1 signaling promotes migration of intestinal epithelial cells |
Q89599165 | Regulation of Osteoclast Differentiation at Multiple Stages by Protein Kinase D Family Kinases |
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Q34279846 | Role of protein kinase D signaling in pancreatic cancer |
Q28543910 | SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest |
Q30414082 | Sustained protein kinase D activation mediates respiratory syncytial virus-induced airway barrier disruption |
Q34999635 | Synthesis and Structure-Activity Relationships of Benzothienothiazepinone Inhibitors of Protein Kinase D |
Q34784001 | TNF-α potentiates lysophosphatidic acid-induced COX-2 expression via PKD in human colonic myofibroblasts |
Q34295374 | The protein kinase D1 COOH terminus: marker or regulator of enzyme activity? |
Q35372365 | Tyrosine phosphorylation of protein kinase D2 mediates ligand-inducible elimination of the Type 1 interferon receptor |
Q34749929 | Ultraviolet B irradiation and activation of protein kinase D in primary mouse epidermal keratinocytes |
Q53305892 | VEGF stimulates PKD-mediated CREB-dependent orphan nuclear receptor Nurr1 expression: role in VEGF-induced angiogenesis. |
Q92241890 | [Role of protein kinase D1 in regulating the growth, apoptosis and drug sensitivity of oral squamous carcinoma cells] |
Q54365052 | [The shRNA-mediated downregulation of protein kinase D-2 enhanced chemosensitivity of Tca8113]. |
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