Protein kinase D2 mediates lysophosphatidic acid-induced interleukin 8 production in nontransformed human colonic epithelial cells through NF-kappaB

scientific article

Protein kinase D2 mediates lysophosphatidic acid-induced interleukin 8 production in nontransformed human colonic epithelial cells through NF-kappaB is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPCELL.00308.2006
P3181OpenCitations bibliographic resource ID3371061
P698PubMed publication ID16928771

P2093author name stringMary Pat Moyer
Robert M Strieter
Enrique Rozengurt
Wai Yin Leung
Terence T Chiu
P2860cites workPKCnu, a new member of the protein kinase C family, composes a fourth subfamily with PKCmuQ22009498
Molecular cloning and characterization of the human protein kinase D2. A novel member of the protein kinase D family of serine threonine kinasesQ24290476
Protein kinase D regulates the fission of cell surface destined transport carriers from the trans-Golgi networkQ24290905
Protein kinase D2 mediates activation of nuclear factor kappaB by Bcr-Abl in Bcr-Abl+ human myeloid leukemia cellsQ24323078
Protein kinase D mediates a stress-induced NF-kappaB activation and survival pathwayQ24337864
Cell-type specific phosphorylation of threonines T654 and T669 by PKD defines the signal capacity of the EGF receptorQ24529868
Intracellular redistribution of protein kinase D2 in response to G-protein-coupled receptor agonistsQ28184878
Regulated production of interferon-inducible T-cell chemoattractants by human intestinal epithelial cellsQ28201575
Mechanism of activation of protein kinase D2(PKD2) by the CCK(B)/gastrin receptorQ28203785
Protein kinase D regulates vesicular transport by phosphorylating and activating phosphatidylinositol-4 kinase IIIbeta at the Golgi complexQ28267260
Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase CQ28270392
G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the {beta}-catenin pathwayQ33771080
Protein kinase D mediates mitochondrion-to-nucleus signaling and detoxification from mitochondrial reactive oxygen speciesQ34097117
Repetitive stunning, hibernation, and heart failure: contribution of PET to establishing a linkQ34141218
TLR signaling in the gut in health and diseaseQ34409408
Activation of protein kinase D3 by signaling through Rac and the alpha subunits of the heterotrimeric G proteins G12 and G13.Q34455784
Lysophospholipid G protein-coupled receptorsQ35692411
Protein kinase D signalingQ36035199
Events at the host-microbial interface of the gastrointestinal tract. II. Role of the intestinal epithelium in pathogen-induced inflammationQ36096652
The role of protein kinase C in gastrointestinal function and diseaseQ36154400
Epithelial cells and their neighbors I. Role of intestinal myofibroblasts in development, repair, and cancerQ36165802
Overexpression of protein kinase C betaII induces colonic hyperproliferation and increased sensitivity to colon carcinogenesisQ36256627
Phosphorylation of histone deacetylase 7 by protein kinase D mediates T cell receptor-induced Nur77 expression and apoptosisQ36402725
Protein kinase Cdelta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signalingQ37011824
Regulation of lysophosphatidic acid-induced epidermal growth factor receptor transactivation and interleukin-8 secretion in human bronchial epithelial cells by protein kinase Cdelta, Lyn kinase, and matrix metalloproteinasesQ37385067
Induction of cIAP-2 in Human Colon Cancer Cells through PKCδ/NF-κBQ38349616
Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytesQ40322638
The Vi capsular antigen of Salmonella enterica serotype Typhi reduces Toll-like receptor-dependent interleukin-8 expression in the intestinal mucosa.Q40419113
Neurotensin stimulates interleukin-8 expression through modulation of I kappa B alpha phosphorylation and p65 transcriptional activity: involvement of protein kinase C alpha.Q40448923
Lysophospholipids increase ICAM-1 expression in HUVEC through a Gi- and NF-kappaB-dependent mechanismQ40528453
Regulation of phorbol ester-mediated TRAF1 induction in human colon cancer cells through a PKC/RAF/ERK/NF-kappaB-dependent pathwayQ40586194
Regulation of airway epithelial cell NF-kappa B-dependent gene expression by protein kinase C deltaQ40646086
Protein kinase D complexes with C-Jun N-terminal kinase via activation loop phosphorylation and phosphorylates the C-Jun N-terminusQ40738836
Protein kinase D is sufficient to suppress EGF-induced c-Jun Ser 63 phosphorylationQ40799943
Modulation of intestinal epithelial wound healing in vitro and in vivo by lysophosphatidic acid.Q40939698
PKCdelta acts as a growth and tumor suppressor in rat colonic epithelial cellsQ40972626
Protein kinase C isozyme-mediated cell cycle arrest involves induction of p21(waf1/cip1) and p27(kip1) and hypophosphorylation of the retinoblastoma protein in intestinal epithelial cellsQ41116723
Transcriptional regulation of lysophosphatidic acid-induced interleukin-8 expression and secretion by p38 MAPK and JNK in human bronchial epithelial cellsQ42221164
Expression of the protein kinase D (PKD) family during mouse embryogenesisQ42676665
NCM460, a normal human colon mucosal epithelial cell lineQ42812955
Protein kinase D potentiates DNA synthesis and cell proliferation induced by bombesin, vasopressin, or phorbol esters in Swiss 3T3 cellsQ42826316
Stimulation of phospholipase D by epidermal growth factor requires protein kinase C activation in Swiss 3T3 cellsQ42829828
Protein kinase D potentiates DNA synthesis induced by Gq-coupled receptors by increasing the duration of ERK signaling in swiss 3T3 cellsQ42831514
Role of diacylglycerol in PKD recruitment to the TGN and protein transport to the plasma membraneQ43812838
Induction of cyclooxygenase-2 overexpression in human gastric epithelial cells by Helicobacter pylori involves TLR2/TLR9 and c-Src-dependent nuclear factor-kappaB activation.Q44087162
Protein kinase C nu/protein kinase D3 nuclear localization, catalytic activation, and intracellular redistribution in response to G protein-coupled receptor agonistsQ44391310
Activation loop phosphorylation controls protein kinase D-dependent activation of nuclear factor kappaB.Q44958771
LPA2 receptor mediates mitogenic signals in human colon cancer cellsQ45281003
Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves protein kinase Cdelta activationQ46510703
Lung endothelial cell proliferation with decreased shear stress is mediated by reactive oxygen speciesQ46656372
Interleukin-8 secretion by fibroblasts induced by low density lipoproteins is p38 MAPK-dependent and leads to cell spreading and wound closureQ46775960
EPEC-activated ERK1/2 participate in inflammatory response but not tight junction barrier disruptionQ50113307
Transcriptional activation of interleukin-8 by beta-catenin-Tcf4.Q52115561
Protein kinase D directly phosphorylates histone deacetylase 5 via a random sequential kinetic mechanismQ57358995
Involvement of PKCα/β in TLR4 and TLR2 dependent activation of NF-κBQ57359987
Protein kinase C alpha modulates growth and differentiation in Caco-2 cellsQ74298189
Downregulation of the colon tumour-suppressor homeobox gene Cdx-2 by oncogenic rasQ77931485
Ethanol sensitizes NF-kappaB activation in pancreatic acinar cells through effects on protein kinase C-epsilonQ83019149
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectinterleukinsQ194908
NF-κBQ411114
positive regulation of NF-kappaB transcription factor activityQ14761969
Protein kinase D2Q21113377
P304page(s)C767-77
P577publication date2007-02-01
P1433published inAmerican Journal of Physiology - Cell PhysiologyQ2227080
P1476titleProtein kinase D2 mediates lysophosphatidic acid-induced interleukin 8 production in nontransformed human colonic epithelial cells through NF-kappaB
P478volume292

Reverse relations

cites work (P2860)
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