| P2093 | author name string | Enrique Rozengurt | |
| | James Sinnett-Smith | |
| | Yang Ni | |
| | Steven H Young | |
| P2860 | cites work | Mitochondrial dysfunction in Pten haplo-insufficient mice with social deficits and repetitive behavior: interplay between Pten and p53 | Q21560776 |
| | Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex | Q24295120 |
| | mTOR signaling in growth control and disease | Q24634174 |
| | Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis | Q24681977 |
| | AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation | Q28139447 |
| | Protein kinase D2 potentiates MEK/ERK/RSK signaling, c-Fos accumulation and DNA synthesis induced by bombesin in Swiss 3T3 cells | Q28594706 |
| | The emerging mechanisms of isoform-specific PI3K signalling | Q29617954 |
| | Activation of protein kinase D by signaling through the alpha subunit of the heterotrimeric G protein G(q). | Q41714408 |
| | Lysophosphatidic acid rapidly induces protein kinase D activation through a pertussis toxin-sensitive pathway | Q41715660 |
| | Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR. | Q42091923 |
| | Protein kinase D mediates mitogenic signaling by Gq-coupled receptors through protein kinase C-independent regulation of activation loop Ser744 and Ser748 phosphorylation. | Q42136685 |
| | Identification of in vivo phosphorylation sites required for protein kinase D activation. | Q42462150 |
| | Activation of protein kinase D by signaling through Rho and the alpha subunit of the heterotrimeric G protein G13. | Q42508695 |
| | Protein kinase D potentiates DNA synthesis and cell proliferation induced by bombesin, vasopressin, or phorbol esters in Swiss 3T3 cells | Q42826316 |
| | Protein kinase D potentiates DNA synthesis induced by Gq-coupled receptors by increasing the duration of ERK signaling in swiss 3T3 cells | Q42831514 |
| | p85 regulatory subunit of PI3K mediates cAMP-PKA and estrogens biological effects on growth and survival | Q42834858 |
| | Integration of phosphoinositide- and calmodulin-mediated regulation of TRPC6. | Q42846604 |
| | Protein kinase C phosphorylates protein kinase D activation loop Ser744 and Ser748 and releases autoinhibition by the pleckstrin homology domain. | Q44198663 |
| | Cooperation of Gq, Gi, and G12/13 in protein kinase D activation and phosphorylation induced by lysophosphatidic acid | Q44246034 |
| | Establishment and characterizaton of intestinal epithelial cell cultures | Q44431913 |
| | Galphaq/11 signaling induces apoptosis through two pathways involving reduction of Akt phosphorylation and activation of RhoA in HeLa cells | Q44970208 |
| | Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling | Q73754511 |
| | Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/Protein kinase Cmu | Q78208164 |
| | Vascular endothelial growth factor receptor-1 regulates postnatal angiogenesis through inhibition of the excessive activation of Akt | Q81534799 |
| | p53 Mediates the accelerated onset of senescence of endothelial progenitor cells in diabetes | Q81598661 |
| | A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo | Q30495531 |
| | Regulation of PTEN activity by p38δ-PKD1 signaling in neutrophils confers inflammatory responses in the lung | Q30528488 |
| | Gastrin, CCK, signaling, and cancer | Q31963603 |
| | Induced overexpression of protein kinase D1 stimulates mitogenic signaling in human pancreatic carcinoma PANC-1 cells | Q33923820 |
| | Role of beta-arrestin 1 in the metastatic progression of colorectal cancer | Q34335080 |
| | Protein Kinase D1 Mediates Stimulation of DNA Synthesis and Proliferation in Intestinal Epithelial IEC-18 Cells and in Mouse Intestinal Crypts | Q34452638 |
| | Activation of protein kinase D3 by signaling through Rac and the alpha subunits of the heterotrimeric G proteins G12 and G13. | Q34455784 |
| | AKT inhibition relieves feedback suppression of receptor tyrosine kinase expression and activity | Q34511038 |
| | A network of immediate early gene products propagates subtle differences in mitogen-activated protein kinase signal amplitude and duration. | Q34551716 |
| | Sustained activation of Akt elicits mitochondrial dysfunction to block Plasmodium falciparum infection in the mosquito host | Q34611134 |
| | Inhibition of PI3K binding to activators by serine phosphorylation of PI3K regulatory subunit p85alpha Src homology-2 domains | Q35180699 |
| | A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types | Q35215580 |
| | Protein kinase D signaling: multiple biological functions in health and disease | Q35239280 |
| | Akt fine-tunes NF-κB-dependent gene expression during T cell activation | Q35371427 |
| | Regulation of phosphoinositide 3-kinase by its intrinsic serine kinase activity in vivo. | Q35544459 |
| | Differential PKC-dependent and -independent PKD activation by G protein α subunits of the Gq family: selective stimulation of PKD Ser⁷⁴⁸ autophosphorylation by Gαq. | Q35778013 |
| | Class IA phosphoinositide 3-kinases are obligate p85-p110 heterodimers | Q35808718 |
| | Inhibition of PI3K/mTOR leads to adaptive resistance in matrix-attached cancer cells | Q35816378 |
| | Protein kinase D signaling | Q36035199 |
| | Muscarinic type 3 receptor induces cytoprotective signaling in salivary gland cells through epidermal growth factor receptor transactivation | Q36057390 |
| | Rapid protein kinase D1 signaling promotes migration of intestinal epithelial cells | Q36175932 |
| | Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria | Q36200458 |
| | Sequential protein kinase C (PKC)-dependent and PKC-independent protein kinase D catalytic activation via Gq-coupled receptors: differential regulation of activation loop Ser(744) and Ser(748) phosphorylation | Q36741576 |
| | Mitogenic signaling pathways induced by G protein-coupled receptors | Q36929839 |
| | Many roads lead to oncogene-induced senescence | Q37056216 |
| | Gastrointestinal growth factors and hormones have divergent effects on Akt activation. | Q37180159 |
| | PI3K/Akt: getting it right matters | Q37310202 |
| | Gq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation | Q38264143 |
| | Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway | Q39316242 |
| | p85α SH2 domain phosphorylation by IKK promotes feedback inhibition of PI3K and Akt in response to cellular starvation | Q39395442 |
| | Gq-coupled purinergic receptors inhibit insulin-like growth factor-I/phosphoinositide 3-kinase pathway-dependent keratinocyte migration. | Q39570926 |
| | Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells. | Q39823738 |
| | Constitutively active alpha subunits of G(q/11) and G(12/13) families inhibit activation of the pro-survival Akt signaling cascade | Q40279257 |
| | EGF receptor transactivation mediates ANG II-stimulated mitogenesis in intestinal epithelial cells through the PI3-kinase/Akt/mTOR/p70S6K1 signaling pathway | Q40517007 |
| | Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells | Q40591335 |
| | PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity. | Q40790718 |
| | Activation loop Ser744 and Ser748 in protein kinase D are transphosphorylated in vivo. | Q40798561 |
| | PKD in intestinal epithelial cells: rapid activation by phorbol esters, LPA, and angiotensin through PKC. | Q40821330 |
| P275 | copyright license | Creative Commons CC0 License | Q6938433 |
| P6216 | copyright status | copyrighted, dedicated to the public domain by copyright holder | Q88088423 |
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | G protein-coupled receptor | Q38173 |
| P304 | page(s) | e73149 | |
| P577 | publication date | 2013-09-09 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | PKD1 mediates negative feedback of PI3K/Akt activation in response to G protein-coupled receptors | |
| P478 | volume | 8 | |