| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Mary C Farach-Carson | |
| Daniel D Carson | |||
| Catherine Kirn-Safran | |||
| P2860 | cites work | Heparan sulfate structure in mice with genetically modified heparan sulfate production | Q80413581 |
| Microfibrils at basement membrane zones interact with perlecan via fibrillin-1 | Q81289350 | ||
| Transgenic or tumor-induced expression of heparanase upregulates sulfation of heparan sulfate | Q81474966 | ||
| Heparan sulfate of perlecan is involved in glomerular filtration | Q81716389 | ||
| Reduced perlecan expression and accumulation in human carotid atherosclerotic lesions | Q83168047 | ||
| PI-88: a novel inhibitor of angiogenesis | Q94801394 | ||
| Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival | Q21144445 | ||
| Glypicans | Q21183908 | ||
| The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate | Q22011093 | ||
| Collagen XVIII, containing an endogenous inhibitor of angiogenesis and tumor growth, plays a critical role in the maintenance of retinal structure and in neural tube closure (Knobloch syndrome) | Q24273425 | ||
| Characterization of Slit protein interactions with glypican-1 | Q24291266 | ||
| Heparanase mediates cell adhesion independent of its enzymatic activity | Q24303492 | ||
| Structural recognition by recombinant human heparanase that plays critical roles in tumor metastasis. Hierarchical sulfate groups with different effects and the essential target disulfated trisaccharide sequence | Q24306149 | ||
| Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans | Q24309373 | ||
| Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome | Q24320198 | ||
| Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney | Q24540314 | ||
| Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma | Q24651026 | ||
| Heparan sulphate synthetic and editing enzymes in ovarian cancer | Q24653774 | ||
| Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2 | Q24673634 | ||
| Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity | Q24673740 | ||
| QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling | Q24675509 | ||
| Perlecan maintains the integrity of cartilage and some basement membranes | Q24680954 | ||
| Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4 | Q24681644 | ||
| Heparan sulfate biosynthesis enzymes EXT1 and EXT2 affect NDST1 expression and heparan sulfate sulfation | Q28115828 | ||
| Glypican-3-deficient mice exhibit developmental overgrowth and some of the abnormalities typical of Simpson-Golabi-Behmel syndrome | Q28139404 | ||
| Perlecan is essential for cartilage and cephalic development | Q28146148 | ||
| The splice variants of vascular endothelial growth factor (VEGF) and their receptors | Q28200155 | ||
| Cloning of an immunoglobulin family adhesion molecule selectively expressed by endothelial cells | Q28208656 | ||
| Signalling by HGF/SF and Met: the role of heparan sulphate co-receptors | Q28240994 | ||
| Glypican-1 as an Abeta binding HSPG in the human brain: its localization in DIG domains and possible roles in the pathogenesis of Alzheimer's disease | Q28256486 | ||
| Integral membrane heparan sulfate proteoglycans | Q28262453 | ||
| The Frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases | Q28274567 | ||
| Processing by convertases is not required for glypican-3-induced stimulation of hepatocellular carcinoma growth | Q28277212 | ||
| Defective neuromuscular synaptogenesis in agrin-deficient mutant mice | Q28280786 | ||
| BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan | Q28297745 | ||
| Agrin is a chimeric proteoglycan with the attachment sites for heparan sulfate/chondroitin sulfate located in two multiple serine-glycine clusters | Q28505873 | ||
| Structurally altered basement membranes and hydrocephalus in a type XVIII collagen deficient mouse line | Q28507183 | ||
| Lack of collagen XVIII/endostatin results in eye abnormalities | Q28511317 | ||
| WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan | Q28512220 | ||
| Alternatively spliced isoforms of nerve- and muscle-derived agrin: their roles at the neuromuscular junction | Q28513062 | ||
| The molecular phenotype of heparan sulfate in the Hs2st-/- mutant mouse | Q28513833 | ||
| Characterization of heparanase from a rat parathyroid cell line | Q28566513 | ||
| Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice | Q28586958 | ||
| Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme | Q28586968 | ||
| Altered hematopoiesis in glypican-3-deficient mice results in decreased osteoclast differentiation and a delay in endochondral ossification | Q28587283 | ||
| Mammalian Brain Morphogenesis and Midline Axon Guidance Require Heparan Sulfate | Q28588474 | ||
| Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase | Q28589603 | ||
| Targeted disruption of a murine glucuronyl C5-epimerase gene results in heparan sulfate lacking L-iduronic acid and in neonatal lethality | Q28591170 | ||
| Defective heparan sulfate biosynthesis and neonatal lethality in mice lacking N-deacetylase/N-sulfotransferase-1 | Q28591609 | ||
| Mice deficient in Ext2 lack heparan sulfate and develop exostoses | Q28592253 | ||
| Mice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation, and late embryonic lethality | Q28592475 | ||
| Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function | Q28592534 | ||
| Mice deficient in heparan sulfate 3-O-sulfotransferase-1: Normal hemostasis with unexpected perinatal phenotypes | Q29041315 | ||
| Order out of chaos: assembly of ligand binding sites in heparan sulfate | Q29620085 | ||
| Agrin and neuregulin, expanding roles and implications for therapeutics | Q37068224 | ||
| Novel interactions of perlecan: unraveling perlecan's role in angiogenesis. | Q37094730 | ||
| Fibrinogen facilitates the anti-tumor effect of nonnative endostatin | Q37177297 | ||
| Revisiting the glomerular charge barrier in the molecular era. | Q37228168 | ||
| Heparanase: one molecule with multiple functions in cancer progression | Q37228578 | ||
| Muscular dystrophies due to glycosylation defects | Q37329563 | ||
| Heparan sulfate in perlecan promotes mouse atherosclerosis: roles in lipid permeability, lipid retention, and smooth muscle cell proliferation | Q37395446 | ||
| QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis | Q37415156 | ||
| Essential and separable roles for Syndecan-3 and Syndecan-4 in skeletal muscle development and regeneration. | Q37522362 | ||
| Mice lacking the syndecan-3 gene are resistant to diet-induced obesity. | Q37591908 | ||
| Characterization of heparan sulfate oligosaccharides that bind to hepatocyte growth factor | Q38288128 | ||
| 6-O-sulfation of heparan sulfate differentially regulates various fibroblast growth factor-dependent signalings in culture | Q38293479 | ||
| Loss of HSulf-1 expression enhances autocrine signaling mediated by amphiregulin in breast cancer. | Q38303667 | ||
| Heparan sulfate Ndst1 gene function variably regulates multiple signaling pathways during mouse development | Q38306324 | ||
| Sequence analysis of heparan sulphate and heparin oligosaccharides | Q38325522 | ||
| Structure of a heparan sulphate oligosaccharide that binds to basic fibroblast growth factor | Q38327052 | ||
| Perlecan binds to the beta-amyloid proteins (A beta) of Alzheimer's disease, accelerates A beta fibril formation, and maintains A beta fibril stability. | Q39115406 | ||
| Overproduction of perlecan core protein in cultured cells and transgenic mice | Q39121464 | ||
| Collagen XVIII/endostatin is essential for vision and retinal pigment epithelial function. | Q39315528 | ||
| Tyrosine dephosphorylation of the syndecan-1 PDZ binding domain regulates syntenin-1 recruitment | Q39882042 | ||
| The frizzled extracellular domain is a ligand for Van Gogh/Stbm during nonautonomous planar cell polarity signaling | Q39937859 | ||
| A novel peptide sequence in perlecan domain IV supports cell adhesion, spreading and FAK activation | Q40053261 | ||
| Heparanase expression and function during early pregnancy in mice. | Q40131935 | ||
| Endorepellin in vivo: targeting the tumor vasculature and retarding cancer growth and metabolism | Q40208428 | ||
| Syndecan-2 is expressed in the microvasculature of gliomas and regulates angiogenic processes in microvascular endothelial cells | Q40297851 | ||
| Structure and laminin-binding specificity of the NtA domain expressed in eukaryotic cells. | Q40461722 | ||
| Sodium channel beta1 subunits promote neurite outgrowth in cerebellar granule neurons | Q40510241 | ||
| Differential regulation of hepatocyte growth factor/scatter factor by cell surface proteoglycans and free glycosaminoglycan chains | Q40952245 | ||
| Acetylcholine receptors and the cytoskeletal connection | Q41143605 | ||
| The core protein of growth plate perlecan binds FGF-18 and alters its mitogenic effect on chondrocytes | Q41489080 | ||
| Processing by proprotein convertases is required for glypican-3 modulation of cell survival, Wnt signaling, and gastrulation movements | Q41871371 | ||
| Molecular behavior adapts to context: heparanase functions as an extracellular matrix-degrading enzyme or as a T cell adhesion molecule, depending on the local pH. | Q41880677 | ||
| Syndecan-3-deficient mice exhibit enhanced LTP and impaired hippocampus-dependent memory | Q42526526 | ||
| Motifs of cadherin- and fibronectin type III-related sequences and evolution of the receptor-type-protein tyrosine kinases: sequence similarity between proto-oncogene ret and cadherin family | Q42616776 | ||
| Reduced perlecan in mice results in chondrodysplasia resembling Schwartz-Jampel syndrome | Q42832135 | ||
| HIP/RPL29 antagonizes VEGF and FGF2 stimulated angiogenesis by interfering with HS-dependent responses. | Q43096150 | ||
| Defects in keratinocyte activation during wound healing in the syndecan-1-deficient mouse | Q44204092 | ||
| Lack of type XVIII collagen results in anterior ocular defects | Q44606546 | ||
| Transgenic expression of mammalian heparanase uncovers physiological functions of heparan sulfate in tissue morphogenesis, vascularization, and feeding behavior | Q44760488 | ||
| Heparan sulfate synthesized by mouse embryonic stem cells deficient in NDST1 and NDST2 is 6-O-sulfated but contains no N-sulfate groups | Q45023582 | ||
| Inhibition by the soluble syndecan-1 ectodomains delays wound repair in mice overexpressing syndecan-1. | Q47283049 | ||
| Perlecan, the major proteoglycan of basement membranes, is altered in patients with Schwartz-Jampel syndrome (chondrodystrophic myotonia). | Q47810194 | ||
| Heparan sulphation patterns generated by specific heparan sulfotransferase enzymes direct distinct aspects of retinal axon guidance at the optic chiasm. | Q48484123 | ||
| Amyloid beta induces cellular relocalization and production of agrin and glypican-1. | Q48790464 | ||
| Perlecan is critical for heart stability. | Q48975311 | ||
| Heparanase is expressed in osteoblastic cells and stimulates bone formation and bone mass. | Q51816706 | ||
| Juvenile syndecan-1 null mice are protected from carcinogen-induced tumor development. | Q52007642 | ||
| Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development. | Q52575004 | ||
| Agrin binds alpha-synuclein and modulates alpha-synuclein fibrillation. | Q53271067 | ||
| Interaction between beta-amyloid protein and heparan sulfate proteoglycans from the cerebral capillary basement membrane in Alzheimer's disease. | Q53397484 | ||
| Agrin is highly expressed by chondrocytes and is required for normal growth. | Q53581329 | ||
| Evidence of neuronal migration disorders in Knobloch syndrome: Clinical and molecular analysis of two novel families | Q53654237 | ||
| [Adhesive glycoproteins of the extracellular matrix] | Q55476925 | ||
| Spectrum ofHSPG2(Perlecan) mutations in patients with Schwartz-Jampel syndrome | Q57639997 | ||
| Syndecan-4 deficiency impairs the fetal vessels in the placental labyrinth | Q58211928 | ||
| Exploitation of syndecan-1 shedding by Pseudomonas aeruginosa enhances virulence | Q59092900 | ||
| Evidence of a dosage effect and a physiological endplate acetylcholinesterase deficiency in the first mouse models mimicking Schwartz–Jampel syndrome neuromyotonia | Q62023500 | ||
| Purification and characterization of placental heparanase and its expression by cultured cytotrophoblasts | Q73549528 | ||
| Syndecan-1 is required for Wnt-1-induced mammary tumorigenesis in mice | Q73977149 | ||
| Heparanase as mediator of angiogenesis: mode of action | Q74101720 | ||
| Increased intimal hyperplasia and smooth muscle cell proliferation in transgenic mice with heparan sulfate-deficient perlecan | Q75318637 | ||
| Transgenic expression of the EXT2 gene in developing chondrocytes enhances the synthesis of heparan sulfate and bone formation in mice | Q77912584 | ||
| Double knockout mice reveal a lack of major functional compensation between collagens XV and XVIII | Q79291370 | ||
| Identification of proteoglycan-binding proteins | Q79369814 | ||
| Syndecan-1/CD147 association is essential for cyclophilin B-induced activation of p44/42 mitogen-activated protein kinases and promotion of cell adhesion and chemotaxis | Q79700174 | ||
| A polymorphism in the angiogenesis inhibitor, endostatin, in lung cancer susceptibility | Q80135645 | ||
| Altered heparan sulfate structure in mice with deleted NDST3 gene function. | Q30488977 | ||
| Heparan sulfate: lessons from knockout mice | Q30689506 | ||
| Cloning, expression, and purification of mouse heparanase | Q33185312 | ||
| Characterization of growth factor-binding structures in heparin/heparan sulfate using an octasaccharide library | Q33196496 | ||
| Eosinophil major basic protein: first identified natural heparanase-inhibiting protein | Q33202066 | ||
| Structural specificity in a FGF7-affinity purified heparin octasaccharide required for formation of a complex with FGF7 and FGFR2IIIb | Q33228058 | ||
| Preparation and use of microarrays containing synthetic heparin oligosaccharides for the rapid analysis of heparin-protein interactions. | Q33261613 | ||
| The elusive functions of proteoglycans: in vivo veritas | Q33825069 | ||
| Extracellular matrix components in retrocorneal fibrous membrane in comparison to corneal endothelium and Descemet's membrane. | Q33895529 | ||
| A polymorphism in endostatin, an angiogenesis inhibitor, predisposes for the development of prostatic adenocarcinoma | Q34095548 | ||
| High serum endostatin levels in Down syndrome: implications for improved treatment and prevention of solid tumours | Q34108448 | ||
| Pathogenesis of beta2-microglobulin amyloidosis | Q34124669 | ||
| Processing of macromolecular heparin by heparanase | Q34210691 | ||
| Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis | Q34328744 | ||
| Interaction of hepatocyte growth factor with heparan sulfate. Elucidation of the major heparan sulfate structural determinants | Q34339506 | ||
| Cloning of cDNA and genomic DNA encoding human type XVIII collagen and localization of the alpha 1(XVIII) collagen gene to mouse chromosome 10 and human chromosome 21. | Q34341595 | ||
| Proteoglycans: pericellular and cell surface multireceptors that integrate external stimuli in the mammary gland | Q34362776 | ||
| Physiological role of collagen XVIII and endostatin | Q34414325 | ||
| Merging extracellular domains: fold prediction for laminin G-like and amino-terminal thrombospondin-like modules based on homology to pentraxins | Q34457974 | ||
| Sulf1 expression pattern and its role in cartilage and joint development | Q34576249 | ||
| Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes | Q34989516 | ||
| New insights into the roles of agrin | Q35097331 | ||
| Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity | Q35928165 | ||
| Matrix revolutions: "tails" of basement-membrane components with angiostatic functions | Q36010882 | ||
| Heparan sulfate proteoglycans: key players in cartilage biology. | Q36098139 | ||
| Linker molecules between laminins and dystroglycan ameliorate laminin-alpha2-deficient muscular dystrophy at all disease stages | Q36118063 | ||
| Endostatin signaling and regulation of endothelial cell-matrix interactions | Q36226744 | ||
| Assembly of the postsynaptic membrane at the neuromuscular junction: paradigm lost | Q36357189 | ||
| Syndecans in wound healing, inflammation and vascular biology | Q36649995 | ||
| The heparanome--the enigma of encoding and decoding heparan sulfate sulfation. | Q36751291 | ||
| Perlecan--a multifunctional extracellular proteoglycan scaffold. | Q36795158 | ||
| PI-88 and novel heparan sulfate mimetics inhibit angiogenesis. | Q36880841 | ||
| Constitutive and accelerated shedding of murine syndecan-1 is mediated by cleavage of its core protein at a specific juxtamembrane site | Q36898627 | ||
| Diverse cell signaling events modulated by perlecan. | Q37020797 | ||
| P433 | issue | 21 | |
| P921 | main subject | heparan sulfate proteoglycans | Q66589633 |
| P304 | page(s) | 3421-3434 | |
| P577 | publication date | 2009-07-24 | |
| P1433 | published in | Cellular and Molecular Life Sciences | Q5058352 |
| P1476 | title | Multifunctionality of extracellular and cell surface heparan sulfate proteoglycans | |
| P478 | volume | 66 |
| Q36219477 | A biomechanical role for perlecan in the pericellular matrix of articular cartilage |
| Q39729101 | A cell permeable peptide analog as a potential-specific PET imaging probe for prostate cancer detection |
| Q37636726 | A novel locus for episodic ataxia:UBR4 the likely candidate |
| Q53659725 | Aliphatic Polyethers with Sulfate, Carboxylate, and Hydroxyl Side Groups-Do They Show Anticoagulant Properties? |
| Q36263989 | Antibodies Directed against a Peptide Epitope of a Klebsiella pneumoniae-Derived Protein Are Present in Ankylosing Spondylitis |
| Q37090575 | Auxiliary and Autonomous Proteoglycan Signaling Networks |
| Q35751704 | Detection of multiple autoantibodies in patients with ankylosing spondylitis using nucleic acid programmable protein arrays |
| Q35753633 | Diagnostic and prognostic significance of glypican 5 and glypican 6 gene expression levels in gastric adenocarcinoma |
| Q42739490 | Distinct patterns of endosulfatase gene expression during Xenopus laevis limb development and regeneration |
| Q41889309 | Electric stimulus opens intercellular spaces in skin. |
| Q34323617 | Evidence from human and zebrafish that GPC1 is a biliary atresia susceptibility gene. |
| Q46054367 | Exploiting Heparan Sulfate Proteoglycans in Human Neurogenesis-Controlling Lineage Specification and Fate |
| Q37899107 | Extracellular matrix functions during neuronal migration and lamination in the mammalian central nervous system |
| Q36584437 | Fluorous supported modular synthesis of heparan sulfate oligosaccharides |
| Q36361216 | Glycosaminoglycans are involved in bacterial adherence to lung cells. |
| Q33601245 | Glypican-2 levels in cerebrospinal fluid predict the status of adult hippocampal neurogenesis. |
| Q34869450 | Heparan sulfate modification of the transmembrane receptor CD47 is necessary for inhibition of T cell receptor signaling by thrombospondin-1. |
| Q51889188 | Heparan sulfate sugar modifications mediate the functions of slits and other factors needed for mouse forebrain commissure development. |
| Q36640967 | Heparanase localization during palatogenesis in mice. |
| Q45779893 | Homoserine as an Aspartic Acid Precursor for Synthesis of Proteoglycan Glycopeptide Containing Aspartic Acid and a Sulfated Glycan Chain. |
| Q34388375 | Increased expression of chondroitin sulphate proteoglycans in rat hepatocellular carcinoma tissues |
| Q42184028 | Injectable perlecan domain 1-hyaluronan microgels potentiate the cartilage repair effect of BMP2 in a murine model of early osteoarthritis |
| Q38290964 | Integrated Approach to Identify Heparan Sulfate Ligand Requirements of Robo1. |
| Q50571168 | Modulating Glypican4 suppresses tumorigenicity of embryonic stem cells while preserving self-renewal and pluripotency. |
| Q42912435 | Modulation of network activity and induction of homeostatic synaptic plasticity by enzymatic removal of heparan sulfates |
| Q33565903 | New glucuronic acid donors for the modular synthesis of heparan sulfate oligosaccharides |
| Q38552681 | Perlecan/Hspg2 deficiency alters the pericellular space of the lacunocanalicular system surrounding osteocytic processes in cortical bone. |
| Q39698792 | Pigment epithelium-derived factor (PEDF): a novel trophoblast-derived factor limiting feto-placental angiogenesis in late pregnancy. |
| Q89757731 | Pingyangmycin inhibits glycosaminoglycan sulphation in both cancer cells and tumour tissues |
| Q35821653 | Prostaglandins in cancer cell adhesion, migration, and invasion |
| Q35599740 | Proteoglycan-based diversification of disease outcome in head and neck cancer patients identifies NG2/CSPG4 and syndecan-2 as unique relapse and overall survival predicting factors. |
| Q26865932 | Proteoglycans in the central nervous system: role in development, neural repair, and Alzheimer's disease |
| Q39317791 | Simple and rapid quality control of sulfated glycans by a fluorescence sensor assay--exemplarily developed for the sulfated polysaccharides from red algae Delesseria sanguinea |
| Q27313760 | Specific syndecan-1 domains regulate mesenchymal tumor cell adhesion, motility and migration |
| Q37359574 | Surface glycosaminoglycans mediate adherence between HeLa cells and Lactobacillus salivarius Lv72. |
| Q39293285 | Synthesis, separation, and characterization of amphiphilic sulfated oligosaccharides enabled by reversed-phase ion pairing LC and LC-MS methods |
| Q38949781 | The function of heparan sulfate during branching morphogenesis |
| Q36208202 | The proteoglycan repertoire of lymphoid cells |
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