Influence of miR-155 on Cell Apoptosis in Rats with Ischemic Stroke: Role of the Ras Homolog Enriched in Brain (Rheb)/mTOR Pathway.

scientific article published on 27 December 2016

Influence of miR-155 on Cell Apoptosis in Rats with Ischemic Stroke: Role of the Ras Homolog Enriched in Brain (Rheb)/mTOR Pathway. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.12659/MSM.898980
P932PMC publication ID5215517
P698PubMed publication ID28025572

P2093author name stringXiaowei Xu
Xudong Pan
Guoping Xing
Zengxiang Luo
Chi Zhong
P2860cites workThe Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residuesQ24318951
mTOR signaling in growth control and diseaseQ24634174
Inositol phosphatase SHIP1 is a primary target of miR-155Q24648984
Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorderQ24649158
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signalingQ24672005
Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's diseaseQ24685592
Pathobiology of ischaemic stroke: an integrated viewQ28141682
Rheb binds and regulates the mTOR kinaseQ28247033
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Reversible middle cerebral artery occlusion without craniectomy in ratsQ28268048
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The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsyQ28579751
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward RhebQ28646935
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The immunology of stroke: from mechanisms to translationQ29620066
TOR signalingQ30312086
Delayed postconditioning protects against focal ischemic brain injury in ratsQ33391388
Inflammatory mechanisms in ischemic stroke: role of inflammatory cellsQ33806613
mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging.Q34129574
Inducible microRNA-155 Feedback Promotes Type I IFN Signaling in Antiviral Innate Immunity by Targeting Suppressor of Cytokine Signaling 1Q34142942
Limited diagnostic value of microRNAs for detecting colorectal cancer: a meta-analysisQ35003740
MicroRNA-155 promotes autophagy to eliminate intracellular mycobacteria by targeting RhebQ35018081
Unraveling the ischemic brain transcriptome in a permanent middle cerebral artery occlusion mouse model by DNA microarray analysisQ35794591
Acetylbritannilactone Modulates MicroRNA-155-Mediated Inflammatory Response in Ischemic Cerebral TissuesQ35855650
Hepatitis C virus activates the mTOR/S6K1 signaling pathway in inhibiting IRS-1 function for insulin resistanceQ36023170
An activated protein C analog with reduced anticoagulant activity extends the therapeutic window of tissue plasminogen activator for ischemic stroke in rodents.Q36195195
Association Between Single-Nucleotide Polymorphism (SNP) in miR-146a, miR-196a2, and miR-499 and Risk of Ischemic Stroke: A Meta-AnalysisQ36336428
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ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivoQ36802449
Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic eventsQ36843531
Constitutively active Rheb induces oncogenic transformationQ36926241
Rheb/mTORC1 Signaling Promotes Kidney Fibroblast Activation and FibrosisQ36977335
The Akt signaling pathway contributes to postconditioning's protection against stroke; the protection is associated with the MAPK and PKC pathwaysQ37352314
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Inhibition of mammalian target of rapamycin improves neurobehavioral deficit and modulates immune response after intracerebral hemorrhage in rat.Q37684935
Functions and regulation of the 70kDa ribosomal S6 kinases.Q37798912
Stroke and the immune system: from pathophysiology to new therapeutic strategiesQ37867782
Regulation of mRNA translation by signaling pathwaysQ38034202
RHEB expression in fibroadenomas of the breastQ38292912
Hydrogen peroxide induces Beclin 1-independent autophagic cell death by suppressing the mTOR pathway via promoting the ubiquitination and degradation of Rheb in GSH-depleted RAW 264.7 cellsQ39633655
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's diseaseQ40887263
miR-155 suppresses bacterial clearance in Pseudomonas aeruginosa-induced keratitis by targeting RhebQ42233667
Effects of RhebL1 silencing on the mTOR pathwayQ42809747
Rheb is in a high activation state and inhibits B-Raf kinase in mammalian cellsQ44127157
Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficienciesQ45067792
Protective effects of ischemic postconditioning compared with gradual reperfusion or preconditioning.Q46002052
Characterization of the intrinsic and TSC2-GAP-regulated GTPase activity of Rheb by real-time NMR.Q46142408
Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancementQ46473927
Neuroprotection Induced In Vitro by Ischemic Preconditioning and Postconditioning: Modulation of Apoptosis and PI3K–Akt PathwaysQ54642083
Treatment of acute ischemic strokeQ74271135
[Cerebral stroke: problems and solutions]Q75202844
Treatment with edaravone attenuates ischemic brain injury and inhibits neurogenesis in the subventricular zone of adult rats after focal cerebral ischemia and reperfusion injuryQ82673279
Essential Role of MicroRNA-155 in Regulating Endothelium-Dependent Vasorelaxation by Targeting Endothelial Nitric Oxide SynthaseQ85309830
Analysis of the interferences in quantitation of a site-specifically PEGylated exendin-4 analog by the Bradford methodQ88128085
P304page(s)5141-5153
P577publication date2016-12-27
P1433published inMedical Science MonitorQ15756323
P1476titleInfluence of miR-155 on Cell Apoptosis in Rats with Ischemic Stroke: Role of the Ras Homolog Enriched in Brain (Rheb)/mTOR Pathway
P478volume22

Reverse relations

cites work (P2860)
Q90124913Circulating MicroRNAs as Potential Noninvasive Biomarkers of Spontaneous Intracerebral Hemorrhage
Q91739673Inhibiting miR-155 protects against myocardial ischemia/reperfusion injury via targeted regulation of HIF-1α in rats
Q64988962Inhibition of MicroRNA-155 Supports Endothelial Tight Junction Integrity Following Oxygen-Glucose Deprivation.
Q90083976Long noncoding RNA BFAL1 mediates enterotoxigenic Bacteroides fragilis-related carcinogenesis in colorectal cancer via the RHEB/mTOR pathway
Q92702014MicroRNA-155 Promotes Myocardial Infarction-Induced Apoptosis by Targeting RNA-Binding Protein QKI
Q88510369MicroRNA-based therapeutics in central nervous system injuries
Q52661746Silencing a Multifunctional microRNA Is Beneficial for Stroke Recovery
Q60310707The Effect of Cerebrovascular Stenosis on -Peri-Hematoma Cerebral Perfusion and Clinical Outcomes in Patients with Supratentorial Spontaneous Intracerebral Hemorrhage
Q91782105microRNA-195 attenuates neuronal apoptosis in rats with ischemic stroke through inhibiting KLF5-mediated activation of the JNK signaling pathway

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