Interleukin-10 is produced by a specific subset of taste receptor cells and critical for maintaining structural integrity of mouse taste buds

scientific article published on February 2014

Interleukin-10 is produced by a specific subset of taste receptor cells and critical for maintaining structural integrity of mouse taste buds is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.3074-13.2014
P932PMC publication ID3921433
P698PubMed publication ID24523558

P2093author name stringHong Wang
Liquan Huang
Pu Feng
Minliang Zhou
Jinghua Chai
Nirvine Simon
P2860cites workGgamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatoniumQ22010827
Inflammation and insulin resistanceQ22241893
A novel family of mammalian taste receptorsQ22253877
The cell biology of tasteQ22337180
Interleukin-10 and the interleukin-10 receptorQ24290912
Endocannabinoids selectively enhance sweet tasteQ24651367
Immunocytochemical evidence for co-expression of Type III IP3 receptor with signaling components of bitter taste transductionQ24797779
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Pathogen recognition and innate immunityQ27861084
A family of candidate taste receptors in human and mouseQ28141865
Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathwaysQ28208630
The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chainQ28259983
Defects in the peripheral taste structure and function in the MRL/lpr mouse model of autoimmune diseaseQ28482449
Expression, physiological action, and coexpression patterns of neuropeptide Y in rat taste-bud cellsQ28583990
Taste bud cell dynamics during normal and sodium-restricted developmentQ44817432
Cell types and lineages in taste budsQ45287717
Clinical evaluation and symptoms of chemosensory impairment: one thousand consecutive cases from the Nasal Dysfunction Clinic in San DiegoQ46813408
IL-10 limits production of pathogenic TNF by M1 myeloid cells through induction of nuclear NF-κB p50 member in Trypanosoma congolense infection-resistant C57BL/6 miceQ46982099
Demonstration and functional analysis of IL-10 receptors in human epidermal cells: decreased expression in psoriatic skin, down-modulation by IL-8, and up-regulation by an antipsoriatic glucocorticosteroid in normal cultured keratinocytesQ62661988
Decline of taste sensitivity in protein deficient adult ratsQ71875380
Immunoregulatory role of IL-10 during superantigen-induced hyporesponsiveness in vivoQ71929873
Regional expression patterns of taste receptors and gustducin in the mouse tongueQ79322953
Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10Q80785928
Gα-gustducin is extensively coexpressed with sweet and bitter taste receptors in both the soft palate and fungiform papillae but has a different functional significanceQ82129211
Expression of sweet receptor components in equine small intestine: relevance to intestinal glucose transportQ84060955
Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouseQ28589701
Genome-wide analysis of gene expression in primate taste buds reveals links to diverse processesQ28752223
Interleukin-10-deficient mice develop chronic enterocolitisQ29547881
The regulation of IL-10 production by immune cellsQ29615479
Voltage-gated sodium channels in taste bud cellsQ33417943
Lipopolysaccharide-induced inflammation attenuates taste progenitor cell proliferation and shortens the life span of taste bud cellsQ33600320
Activation of MyD88 signaling upon staphylococcal enterotoxin binding to MHC class II moleculesQ33809237
Smell and taste disorders: a primary care approach.Q33835562
Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivityQ33853752
The T cells in peripheral taste tissue of healthy human adults: predominant memory T cells and Th-1 cellsQ33913559
Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac.Q33944523
A transient receptor potential channel expressed in taste receptor cellsQ33961827
A2BR adenosine receptor modulates sweet taste in circumvallate taste budsQ34130939
Expression and secretion of TNF-α in mouse taste buds: a novel function of a specific subset of type II taste cellsQ34384787
Gustducin is a taste-cell-specific G protein closely related to the transducinsQ34440920
Inflammation activates the interferon signaling pathways in taste bud cellsQ34583489
Management of smell and taste problems.Q34628086
Tumor necrosis factor: an apoptosis JuNKie?Q35674085
Functional role for interleukin-1 in the injured peripheral taste systemQ35742815
The role of pannexin 1 hemichannels in ATP release and cell-cell communication in mouse taste budsQ35748758
In situ expression of interleukin-10 in noninflamed human gut and in inflammatory bowel diseaseQ35753115
Cerebrospinal fluid interleukin-10 is a potentially useful biomarker in immunocompetent primary central nervous system lymphoma (PCNSL).Q35760627
Nucleoside triphosphate diphosphohydrolase-2 is the ecto-ATPase of type I cells in taste budsQ36402305
The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseasesQ36552432
The taste of carbonationQ36845207
Heterotrimeric G protein subunit Gγ13 is critical to olfactionQ36918120
GABA expression in the mammalian taste bud functions as a route of inhibitory cell-to-cell communicationQ37129467
Inflammation and taste disorders: mechanisms in taste budsQ37312123
Immune cells of the human peripheral taste system: dominant dendritic cells and CD4 T cellsQ37315093
Expression of the voltage-gated potassium channel KCNQ1 in mammalian taste bud cells and the effect of its null-mutation on taste preferencesQ37324475
Nonredundant roles for B cell-derived IL-10 in immune counter-regulationQ37409360
The biology of cachectin/TNF--a primary mediator of the host responseQ38269386
Leptin Modulates Behavioral Responses to Sweet Substances by Influencing Peripheral Taste StructuresQ38348513
T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritationQ42971196
Lipopolysaccharide regulates proinflammatory cytokine expression in mouse myoblasts and skeletal muscleQ44107264
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectinterleukinsQ194908
taste budsQ862867
P304page(s)2689-2701
P577publication date2014-02-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleInterleukin-10 is produced by a specific subset of taste receptor cells and critical for maintaining structural integrity of mouse taste buds
P478volume34

Reverse relations

cites work (P2860)
Q88426160Aggravated gut inflammation in mice lacking the taste signaling protein α-gustducin
Q42364318Cellular mechanisms of cyclophosphamide-induced taste loss in mice
Q64077838Cyclophosphamide and the taste system: Effects of dose fractionation and amifostine on taste cell renewal
Q50133410Gli3 is a negative regulator of Tas1r3-expressing taste cells.
Q52646670Inflammation arising from obesity reduces taste bud abundance and inhibits renewal.
Q59808643Mammalian Taste Bud Cells Utilize Extragemmal 5-Hydroxy-L-Tryptophan to Biosynthesize the Neurotransmitter Serotonin
Q27331622Regulation of bitter taste responses by tumor necrosis factor
Q52091910Taste bud-derived BDNF maintains innervation of a subset of TrkB-expressing gustatory nerve fibers.
Q39196073The Impact of Pregnancy on Taste Function
Q42496891The effect of imiquimod on taste bud calcium transients and transmitter secretion
Q43288442Toll-like receptor 4 mediates fat, sugar, and umami taste preference and food intake and body weight regulation
Q38633204Whole transcriptome profiling of taste bud cells

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