| P2093 | author name string | M Zhang | |
| | D Chen | |
| | L Xing | |
| | G Xiao | |
| | J H Jonason | |
| P2860 | cites work | A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation | Q22003817 |
| | MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2 | Q24294814 |
| | Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation | Q24296392 |
| | Histone deacetylase 7 associates with Runx2 and represses its activity during osteoblast maturation in a deacetylation-independent manner | Q24300259 |
| | Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia | Q24309601 |
| | Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter | Q24537942 |
| | Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis | Q24567977 |
| | Sequence specificity of the core-binding factor | Q24647894 |
| | CHIP promotes Runx2 degradation and negatively regulates osteoblast differentiation | Q24656900 |
| | Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development | Q28119185 |
| | Mutations in the RUNX2 gene in patients with cleidocranial dysplasia | Q28202887 |
| | CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation | Q28216253 |
| | Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation | Q28240596 |
| | Control of RUNX2 isoform expression: the role of promoters and enhancers | Q28245927 |
| | Runx2- and histone deacetylase 3-mediated repression is relieved in differentiating human osteoblast cells to allow high bone sialoprotein expression | Q28254466 |
| | Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation | Q28261166 |
| | Two of four alternatively spliced isoforms of RUNX2 control osteocalcin gene expression in human osteoblast cells | Q28271606 |
| | Parathyroid hormone regulation of the rat collagenase-3 promoter by protein kinase A-dependent transactivation of core binding factor alpha1. | Q40900508 |
| | Inhibition of osteoblast-specific transcription factor Cbfa1 by the cAMP pathway in osteoblastic cells. Ubiquitin/proteasome-dependent regulation. | Q40925745 |
| | Tooth morphogenesis and cell differentiation | Q41239040 |
| | Expression of the PEBP2alphaA/AML3/CBFA1 gene is regulated by BMP4/7 heterodimer and its overexpression suppresses type I collagen and osteocalcin gene expression in osteoblastic and nonosteoblastic mesenchymal cells | Q42451259 |
| | A specific targeting signal directs Runx2/Cbfa1 to subnuclear domains and contributes to transactivation of the osteocalcin gene | Q42511041 |
| | Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha | Q42810037 |
| | Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells | Q42820375 |
| | Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes | Q42934690 |
| | Differential regulation of the two principal Runx2/Cbfa1 n-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype. | Q43715840 |
| | Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism | Q44605245 |
| | Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia. | Q45345530 |
| | Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation. | Q46282462 |
| | Four novel RUNX2 mutations including a splice donor site result in the cleidocranial dysplasia phenotype. | Q46790942 |
| | Osx transcriptional regulation is mediated by additional pathways to BMP2/Smad signaling. | Q50974876 |
| | Type II/III Runx2/Cbfa1 is required for tooth germ development. | Q52030368 |
| | Transcription factors RUNX1/AML1 and RUNX2/Cbfa1 dynamically associate with stationary subnuclear domains. | Q52114278 |
| | PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps. | Q52118956 |
| | Cbfa1 is required for epithelial-mesenchymal interactions regulating tooth development in mice. | Q52176600 |
| | Mechanical stress-mediated Runx2 activation is dependent on Ras/ERK1/2 MAPK signaling in osteoblasts. | Q53574018 |
| | Functional analysis of RUNX2 mutations in cleidocranial dysplasia: novel insights into genotype–phenotype correlations | Q53862836 |
| | The bone-specific transcriptional regulator Cbfa1 is a target of mechanical signals in osteoblastic cells. | Q54504929 |
| | A Pro250Arg substitution in mouse Fgfr1 causes increased expression of Cbfa1 and premature fusion of calvarial sutures | Q56377022 |
| | CBFA1 Mutation Analysis and Functional Correlation with Phenotypic Variability in Cleidocranial Dysplasia | Q61585306 |
| | Hedgehog signaling enhances core-binding factor a1 and receptor activator of nuclear factor-kappaB ligand (RANKL) gene expression in chondrocytes | Q73448985 |
| | Genomic organization, expression of the human CBFA1 gene, and evidence for an alternative splicing event affecting protein function | Q74063837 |
| | Expression of core binding factor Osf2/Cbfa-1 and bone sialoprotein in tooth development | Q77756819 |
| | Characterization of the upstream mouse Cbfa1/Runx2 promoter | Q40786632 |
| | Transcriptional autoregulation of the bone related CBFA1/RUNX2 gene | Q40866240 |
| | AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis | Q28273478 |
| | Runx2: a master organizer of gene transcription in developing and maturing osteoblasts | Q28274182 |
| | Histone deacetylase 3 interacts with runx2 to repress the osteocalcin promoter and regulate osteoblast differentiation | Q28275481 |
| | Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1 | Q28287877 |
| | Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth | Q28505449 |
| | Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis | Q28505748 |
| | PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth | Q28506149 |
| | Maturational disturbance of chondrocytes in Cbfa1-deficient mice | Q28506259 |
| | Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3. | Q28506586 |
| | Phenotypic changes in dentition of Runx2 homozygote-null mutant mice | Q28508216 |
| | Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor | Q28508450 |
| | PTH/PTHrP receptor delays chondrocyte hypertrophy via both Runx2-dependent and -independent pathways | Q28508903 |
| | Causal relationship between the loss of RUNX3 expression and gastric cancer | Q28509530 |
| | Regulation of chondrocyte differentiation by Cbfa1 | Q28509820 |
| | Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation | Q28513591 |
| | Superoxide mediates shock wave induction of ERK-dependent osteogenic transcription factor (CBFA1) and mesenchymal cell differentiation toward osteoprogenitors | Q28565460 |
| | The protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2 | Q28573356 |
| | Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells | Q28573678 |
| | Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity | Q28581756 |
| | Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog | Q28586013 |
| | Conservation and expression of an alternative 3' exon of Runx2 encoding a novel proline-rich C-terminal domain | Q28588614 |
| | Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene | Q28590408 |
| | Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts | Q29547605 |
| | Regulation of human cbfa1 gene transcription in osteoblasts by selective estrogen receptor modulators (SERMs). | Q31017251 |
| | Runx2 phosphorylation induced by fibroblast growth factor-2/protein kinase C pathways | Q33231976 |
| | GSK-3beta controls osteogenesis through regulating Runx2 activity | Q33296995 |
| | Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta | Q33774997 |
| | The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts | Q33953806 |
| | Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12. | Q33966602 |
| | Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2. | Q34002132 |
| | Bone development. | Q34059700 |
| | Histone deacetylase inhibitors promote osteoblast maturation | Q34468553 |
| | Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice | Q35076965 |
| | Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium | Q35106164 |
| | Structure and regulated expression of mammalian RUNX genes | Q35779684 |
| | Neural crest contribution to mammalian tooth formation | Q35843329 |
| | Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development | Q36117930 |
| | Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors | Q36239602 |
| | Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogene | Q36552332 |
| | Advances in Runx2 regulation and its isoforms | Q36562392 |
| | Phenotypic transcription factors epigenetically mediate cell growth control. | Q36638634 |
| | Purification of a mouse nuclear factor that binds to both the A and B cores of the polyomavirus enhancer | Q36783946 |
| | Purification of core-binding factor, a protein that binds the conserved core site in murine leukemia virus enhancers | Q36807821 |
| | Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins | Q36838785 |
| | Regulation of osteogenic differentiation during skeletal development | Q36992331 |
| | Murine and chicken chondrocytes regulate osteoclastogenesis by producing RANKL in response to BMP2 | Q37085639 |
| | Bone morphogenetic protein 2 activates Smad6 gene transcription through bone-specific transcription factor Runx2 | Q37086321 |
| | Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts. | Q37109228 |
| | Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development | Q37109508 |
| | Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo | Q37113932 |
| | Cyclin D1-cdk4 induce runx2 ubiquitination and degradation | Q37113937 |
| | PTHrP prevents chondrocyte premature hypertrophy by inducing cyclin-D1-dependent Runx2 and Runx3 phosphorylation, ubiquitylation and proteasomal degradation | Q37166070 |
| | Role of Runx genes in chondrocyte differentiation | Q38289933 |
| | Multilineage differentiation of Cbfa1-deficient calvarial cells in vitro | Q38310886 |
| | Cbfa1 is a positive regulatory factor in chondrocyte maturation | Q38314367 |
| | Mutations and promoter SNPs in RUNX2, a transcriptional regulator of bone formation. | Q38321488 |
| | Transient upregulation of CBFA1 in response to bone morphogenetic protein-2 and transforming growth factor beta1 in C2C12 myogenic cells coincides with suppression of the myogenic phenotype but is not sufficient for osteoblast differentiation | Q38326843 |
| | Altered gene expression in human cleidocranial dysplasia dental pulp cells | Q38330427 |
| | Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex | Q38344674 |
| | The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons | Q39644959 |
| | Mitotic control of RUNX2 phosphorylation by both CDK1/cyclin B kinase and PP1/PP2A phosphatase in osteoblastic cells | Q40195895 |
| | Alterations in intranuclear localization of Runx2 affect biological activity | Q40232118 |
| | Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation | Q40240553 |
| | Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3. | Q40275083 |
| | Bone morphogenetic protein-2 stimulates Runx2 acetylation | Q40292757 |
| | Modulation of mouse RANKL gene expression by Runx2 and PKA pathway | Q40295089 |
| | Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation | Q40331133 |
| | Serine phosphorylation of RUNX2 with novel potential functions as negative regulatory mechanisms | Q40399719 |
| | BMP-2 and insulin-like growth factor-I mediate Osterix (Osx) expression in human mesenchymal stem cells via the MAPK and protein kinase D signaling pathways | Q40401314 |
| | Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription. | Q40486058 |
| | Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway | Q40526648 |
| | Regulation of TGFbeta1-mediated growth inhibition and apoptosis by RUNX2 isoforms in endothelial cells | Q40563055 |
| | E3 Ubiquitin Ligase Smurf1 Mediates Core-binding Factor α1/Runx2 Degradation and Plays A Specific Role in Osteoblast Differentiation | Q40649010 |
| | Induction of Osteoclast Differentiation by Runx2 through Receptor Activator of Nuclear Factor-κB Ligand (RANKL) and Osteoprotegerin Regulation and Partial Rescue of Osteoclastogenesis in Runx2–/– Mice by RANKL Transgene | Q40655044 |
| | Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells | Q40672808 |
| | IRES-dependent translational control of Cbfa1/Runx2 expression. | Q40676811 |
| | Translational regulation is a control point in RUNX2/Cbfa1 gene expression | Q40767421 |
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cartilage | Q502730 |
| P304 | page(s) | 693-703 | |
| P577 | publication date | 2009-08-01 | |
| P1433 | published in | Journal of Dental Research | Q6295082 |
| P1476 | title | Post-translational Regulation of Runx2 in Bone and Cartilage | |
| P478 | volume | 88 | |