| scholarly article | Q13442814 |
| P50 | author | Hisataka Yasuda | Q104695104 |
| P2093 | author name string | Tatsuya Furuichi | |
| Kazuto Hoshi | |||
| Toshihisa Komori | |||
| Atsuko Mizuno | |||
| Kanji Higashio | |||
| Kenji Takada | |||
| Ryo Fukuyama | |||
| Hirayuki Enomoto | |||
| Reiko Nakamura | |||
| Kazuki Yano | |||
| Carolina A. Yoshida | |||
| Naoko Kanatani | |||
| Akira Zanma | |||
| Satoko Shiojiri | |||
| P2860 | cites work | Endocrine Reviews | Q3054007 |
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| Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation | Q24311588 | ||
| Osteoprotegerin: a novel secreted protein involved in the regulation of bone density | Q24313918 | ||
| TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells | Q24315251 | ||
| A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function | Q24336057 | ||
| RANK is essential for osteoclast and lymph node development | Q24598872 | ||
| osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification | Q24603266 | ||
| A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia | Q24652629 | ||
| Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand | Q24653311 | ||
| Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL | Q24682139 | ||
| Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development | Q28119185 | ||
| RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis | Q28293009 | ||
| Maturational disturbance of chondrocytes in Cbfa1-deficient mice | Q28506259 | ||
| Regulation of chondrocyte differentiation by Cbfa1 | Q28509820 | ||
| Cbfbeta interacts with Runx2 and has a critical role in bone development | Q28586662 | ||
| OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis | Q28589430 | ||
| The core-binding factor beta subunit is required for bone formation and hematopoietic maturation | Q28590530 | ||
| Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts | Q29547605 | ||
| Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee | Q29616160 | ||
| Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12. | Q33966602 | ||
| runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins | Q33967954 | ||
| High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage | Q34285654 | ||
| Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro | Q34459310 | ||
| Runx2, a multifunctional transcription factor in skeletal development | Q34811834 | ||
| Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice | Q35076965 | ||
| Modulation of osteoclast differentiation | Q35957509 | ||
| Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice | Q36201407 | ||
| Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures | Q36293998 | ||
| RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism | Q37108966 | ||
| Multilineage differentiation of Cbfa1-deficient calvarial cells in vitro | Q38310886 | ||
| Runt domain factor (Runx)-dependent effects on CCAAT/ enhancer-binding protein delta expression and activity in osteoblasts | Q38312458 | ||
| Cbfa1 is a positive regulatory factor in chondrocyte maturation | Q38314367 | ||
| Cbfa1 isoforms exert functional differences in osteoblast differentiation | Q38327457 | ||
| Osteoclast differentiation factor mediates an essential signal for bone resorption induced by 1 alpha,25-dihydroxyvitamin D3, prostaglandin E2, or parathyroid hormone in the microenvironment of bone | Q39116021 | ||
| Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin | Q39116155 | ||
| Transgenic mice overexpressing soluble osteoclast differentiation factor (sODF) exhibit severe osteoporosis | Q39124107 | ||
| Cbfa1 does not regulate RANKL gene activity in stromal/osteoblastic cells | Q40746443 | ||
| Stimulation of osteoprotegerin (OPG) gene expression by transforming growth factor-beta (TGF-beta). Mapping of the OPG promoter region that mediates TGF-beta effects | Q40792736 | ||
| The osteoblast-specific transcription factor Cbfa1 contributes to the expression of osteoprotegerin, a potent inhibitor of osteoclast differentiation and function | Q40876662 | ||
| Relative role of CSF-1, MCP-1/JE, and RANTES in macrophage recruitment during successful pregnancy | Q41289951 | ||
| Gene replacement of the p53 gene with the lacZ gene in mouse embryonic stem cells and mice by using two steps of homologous recombination | Q41453701 | ||
| Congenital osteoclast deficiency in osteopetrotic (op/op) mice is cured by injections of macrophage colony-stimulating factor | Q42139985 | ||
| Transcriptional regulation of osteopontin gene in vivo by PEBP2alphaA/CBFA1 and ETS1 in the skeletal tissues | Q42825062 | ||
| Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes | Q42934690 | ||
| Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse | Q43681246 | ||
| CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression. | Q43773224 | ||
| Core-binding factor beta interacts with Runx2 and is required for skeletal development | Q44218113 | ||
| The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation | Q45345527 | ||
| Localization of RANKL (receptor activator of NF kappa B ligand) mRNA and protein in skeletal and extraskeletal tissues. | Q52172979 | ||
| Developmental and liver-specific expression directed by the serum amyloid P component promoter in transgenic mice | Q52231326 | ||
| The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene | Q59092154 | ||
| A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5 | Q64379529 | ||
| Role of colony-stimulating factor-1 in bone metabolism | Q72809748 | ||
| Morphological characterization of skeletal cells in Cbfa1-deficient mice | Q73262148 | ||
| Role of 1 alpha,25-dihydroxyvitamin D3 in osteoclast differentiation and function | Q73787968 | ||
| Impaired vascular invasion of Cbfa1-deficient cartilage engrafted in the spleen | Q74407916 | ||
| Cbfa1 in bone development | Q77210704 | ||
| Potential role of cbfa1, an essential transcriptional factor for osteoblast differentiation, in osteoclastogenesis: regulation of mRNA expression of osteoclast differentiation factor (ODF) | Q77630526 | ||
| P433 | issue | 26 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | biochemistry | Q7094 |
| cell biology | Q7141 | ||
| neoplasm protein | Q66894191 | ||
| P1104 | number of pages | 7 | |
| P304 | page(s) | 23971-23977 | |
| P577 | publication date | 2003-04-15 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Induction of osteoclast differentiation by Runx2 through receptor activator of nuclear factor-kappa B ligand (RANKL) and osteoprotegerin regulation and partial rescue of osteoclastogenesis in Runx2-/- mice by RANKL transgene | |
| Induction of Osteoclast Differentiation by Runx2 through Receptor Activator of Nuclear Factor-κB Ligand (RANKL) and Osteoprotegerin Regulation and Partial Rescue of Osteoclastogenesis in Runx2–/– Mice by RANKL Transgene | |||
| P478 | volume | 278 |
| Q41869707 | A Comparison of the Process of Remodeling of Hydroxyapatite/Poly-D/L-Lactide and Beta-Tricalcium Phosphate in a Loading Site |
| Q36727361 | Anabolic and Antiresorptive Modulation of Bone Homeostasis by the Epigenetic Modulator Sulforaphane, a Naturally Occurring Isothiocyanate |
| Q99406397 | BMP-induced Atoh8 attenuates osteoclastogenesis by suppressing Runx2 transcriptional activity and reducing the Rankl/Opg expression ratio in osteoblasts |
| Q37694830 | Breast cancer cells obtain an osteomimetic feature via epithelial-mesenchymal transition that have undergone BMP2/RUNX2 signaling pathway induction |
| Q53615857 | Cbf beta regulates Runx2 function isoform-dependently in postnatal bone development. |
| Q36279545 | Deletion of core-binding factor β (Cbfβ) in mesenchymal progenitor cells provides new insights into Cbfβ/Runxs complex function in cartilage and bone development |
| Q81387247 | Detection of osteoprotegerin (OPG) and its ligand (RANKL) mRNA and protein in femur and tibia of the rat |
| Q35287635 | Estrogens antagonize RUNX2-mediated osteoblast-driven osteoclastogenesis through regulating RANKL membrane association |
| Q33577294 | Expression of master regulatory genes controlling skeletal development in benign cartilage and bone forming tumors |
| Q53649562 | Expression profile of genes related to osteoclastogenesis in mouse growth plate and articular cartilage. |
| Q35969297 | Fibroblasts regulate variable aggressiveness of syndromic keratocystic and non-syndromic odontogenic tumors |
| Q37611651 | Growth-plate cartilage in chronic renal failure |
| Q35603135 | Homing of cancer cells to the bone |
| Q58788904 | Identification of a novel, methylation-dependent, RUNX2 regulatory region associated with osteoarthritis risk |
| Q34479060 | Increased adipogenesis in cultured embryonic chondrocytes and in adult bone marrow of dominant negative Erg transgenic mice |
| Q34424720 | Kruppel-like factor 4 expression in osteoblasts represses osteoblast-dependent osteoclast maturation |
| Q51711522 | Mapping of the chromosome 17 BMD QTL in the F(2) male mice of MRL/MpJ x SJL/J. |
| Q36661323 | MicroRNA control of bone formation and homeostasis |
| Q34774697 | MicroRNAs Regulate Vascular Medial Calcification |
| Q37516656 | NOTCHing the bone: insights into multi-functionality. |
| Q34773850 | New insights, recent advances, and current challenges in the biological treatment of multiple myeloma |
| Q41174769 | Osteoblast-Specific Loss of IGF1R Signaling Results in Impaired Endochondral Bone Formation During Fracture Healing |
| Q92799706 | Osteoprotegerin reduces osteoclast resorption activity without affecting osteogenesis on nanoparticulate mineralized collagen scaffolds |
| Q33715021 | Osterix overexpression in mesenchymal stem cells stimulates healing of critical-sized defects in murine calvarial bone |
| Q34249099 | Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans |
| Q37026949 | Overexpression of H1 calponin in osteoblast lineage cells leads to a decrease in bone mass by disrupting osteoblast function and promoting osteoclast formation |
| Q39645799 | Overexpression of osteoprotegerin promotes preosteoblast differentiation to mature osteoblasts |
| Q35071181 | Parathyroid hormone controls receptor activator of NF-kappaB ligand gene expression via a distant transcriptional enhancer |
| Q34291256 | Periodontal ligament stem cells modulate root resorption of human primary teeth via Runx2 regulating RANKL/OPG system |
| Q37592911 | Post-translational Regulation of Runx2 in Bone and Cartilage |
| Q50080460 | Prevention of breast cancer-induced osteolytic bone resorption by benzyl isothiocyanate |
| Q36789786 | RUNX2 Mutation Impairs 1α,25-Dihydroxyvitamin D3 mediated Osteoclastogenesis in Dental Follicle Cells |
| Q38061373 | RUNX2 in mammary gland development and breast cancer. |
| Q36860987 | Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulation of bone remodeling in health and disease. |
| Q53372188 | Recombinant osteoprotegerin effects during orthodontic movement in a rat model. |
| Q45762060 | Redefining the activity of a bone-specific transcription factor: novel insights for understanding bone formation |
| Q43612618 | Regulation of Tcf7 by Runx2 in chondrocyte maturation and proliferation |
| Q28281007 | Regulation of adult bone turnover by sex steroids |
| Q24641909 | Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA |
| Q51097637 | Roles of Runx2 in Skeletal Development. |
| Q39181420 | Runx Genes in Breast Cancer and the Mammary Lineage. |
| Q28586013 | Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog |
| Q36616577 | Runx2 and dental development |
| Q40133754 | Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency |
| Q38332288 | Runx2 promotes both osteoblastogenesis and novel osteoclastogenic signals in ST2 mesenchymal progenitor cells. |
| Q48194394 | Runx2, an inducer of osteoblast and chondrocyte differentiation. |
| Q34898865 | Runx2-Smad signaling impacts the progression of tumor-induced bone disease |
| Q34993353 | Runx2-upregulated receptor activator of nuclear factor κB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages. |
| Q34333682 | Selective Runx2-II deficiency leads to low-turnover osteopenia in adult mice |
| Q47985451 | Selective deficiency of the "bone-related" Runx2-II unexpectedly preserves osteoblast-mediated skeletogenesis. |
| Q36917940 | Smooth muscle cell-specific runx2 deficiency inhibits vascular calcification. |
| Q40067295 | Specific inhibition of NLRP3 in chikungunya disease reveals a role for inflammasomes in alphavirus-induced inflammation. |
| Q33894869 | TIEG1/KLF10 modulates Runx2 expression and activity in osteoblasts |
| Q48286134 | The Role of MicroRNA-143-5p in the Differentiation of Dental Pulp Stem Cells into Odontoblasts by Targeting Runx2 via the OPG/RANKL Signaling Pathway |
| Q42463915 | The role of periodontal ligament cells in delayed tooth eruption in patients with cleidocranial dysostosis |
| Q45809237 | Titanium as a Reconstruction and Implant Material in Dentistry: Advantages and Pitfalls |
| Q34621071 | Titanium oral implants: surface characteristics, interface biology and clinical outcome |
| Q43989185 | Trabecular bone microstructure and local gene expression in iliac crest biopsies of men with idiopathic osteoporosis. |
| Q38204490 | Transcriptomic network support distinct roles of classical and non-classical monocytes in human. |
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