scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.M401109200 |
P698 | PubMed publication ID | 15007057 |
P50 | author | L. Darryl Quarles | Q55873742 |
Anita B Hjelmeland | Q79749075 | ||
P2093 | author name string | Zhou-Sheng Xiao | |
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MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes | Q24628843 | ||
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development | Q28119185 | ||
Physical interaction of the activator protein-1 factors c-Fos and c-Jun with Cbfa1 for collagenase-3 promoter activation | Q28201036 | ||
Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation | Q28240596 | ||
Maturational disturbance of chondrocytes in Cbfa1-deficient mice | Q28506259 | ||
Expression of the Runt domain-encoding PEBP2 alpha genes in T cells during thymic development | Q28507097 | ||
Causal relationship between the loss of RUNX3 expression and gastric cancer | Q28509530 | ||
Regulation of chondrocyte differentiation by Cbfa1 | Q28509820 | ||
Genomic structure and isoform expression of the mouse, rat and human Cbfa1/Osf2 transcription factor | Q28577403 | ||
The loss of Smad3 results in a lower rate of bone formation and osteopenia through dysregulation of osteoblast differentiation and apoptosis | Q28593565 | ||
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts | Q29547605 | ||
Expression and function of a stem cell promoter for the murine CBFalpha2 gene: distinct roles and regulation in natural killer and T cell development. | Q30659791 | ||
Phosphate provides an extracellular signal that drives nuclear export of Runx2/Cbfa1 in bone cells | Q31855317 | ||
Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta | Q33774997 | ||
High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage | Q34285654 | ||
FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease | Q34702208 | ||
Distinct requirements for Ras oncogenesis in human versus mouse cells | Q34787097 | ||
Rescue of the skeletal phenotype in CasR-deficient mice by transfer onto the Gcm2 null background | Q34890442 | ||
Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice | Q35076965 | ||
A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development | Q35194624 | ||
Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures | Q36293998 | ||
PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene | Q36436030 | ||
Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogene | Q36552332 | ||
Expression of the human acute myeloid leukemia gene AML1 is regulated by two promoter regions | Q37705859 | ||
A PEBP2 alpha/AML-1-related factor increases osteocalcin promoter activity through its binding to an osteoblast-specific cis-acting element | Q38287692 | ||
Cbfa1 is a positive regulatory factor in chondrocyte maturation | Q38314367 | ||
Cbfa1 isoforms exert functional differences in osteoblast differentiation | Q38327457 | ||
Activation of Peroxisome Proliferator-activated Receptor-γ Inhibits the Runx2-mediated Transcription of Osteocalcin in Osteoblasts | Q40653979 | ||
Induction of Osteoclast Differentiation by Runx2 through Receptor Activator of Nuclear Factor-κB Ligand (RANKL) and Osteoprotegerin Regulation and Partial Rescue of Osteoclastogenesis in Runx2–/– Mice by RANKL Transgene | Q40655044 | ||
IRES-dependent translational control of Cbfa1/Runx2 expression. | Q40676811 | ||
Characterization of the upstream mouse Cbfa1/Runx2 promoter | Q40786632 | ||
MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1. | Q40901916 | ||
Isolation and characterization of the distal promoter region of mouse Cbfa1. | Q40922634 | ||
Expression of the PEBP2alphaA/AML3/CBFA1 gene is regulated by BMP4/7 heterodimer and its overexpression suppresses type I collagen and osteocalcin gene expression in osteoblastic and nonosteoblastic mesenchymal cells | Q42451259 | ||
Expression of the osteoblast differentiation factor RUNX2 (Cbfa1/AML3/Pebp2alpha A) is inhibited by tumor necrosis factor-alpha | Q42513418 | ||
Role of the alpha2-integrin in osteoblast-specific gene expression and activation of the Osf2 transcription factor | Q42824205 | ||
Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2. | Q42826927 | ||
Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes | Q42934690 | ||
Differential expression patterns of Runx2 isoforms in cranial suture morphogenesis | Q43599975 | ||
Runx2 deficiency in chondrocytes causes adipogenic changes in vitro | Q44711017 | ||
Spatio-temporal expression patterns of Runx2 isoforms in early skeletogenesis. | Q51032246 | ||
Architecture and anatomy of the genomic locus encoding the human leukemia-associated transcription factor RUNX1/AML1 | Q57338760 | ||
Runx3 is essential for the target-specific axon pathfinding of trkc-expressing dorsal root ganglion neurons | Q73355288 | ||
Transcriptional mechanisms in osteoblast differentiation and bone formation | Q73763993 | ||
Genomic organization, expression of the human CBFA1 gene, and evidence for an alternative splicing event affecting protein function | Q74063837 | ||
P433 | issue | 19 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | osteoblast | Q917177 |
P304 | page(s) | 20307-20313 | |
P577 | publication date | 2004-03-07 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Selective deficiency of the "bone-related" Runx2-II unexpectedly preserves osteoblast-mediated skeletogenesis | |
P478 | volume | 279 |
Q89495643 | Abnormal expression of miR-135b-5p in bone tissue of patients with osteoporosis and its role and mechanism in osteoporosis progression |
Q37318849 | Advances in osteoclast biology resulting from the study of osteopetrotic mutations. |
Q53615857 | Cbf beta regulates Runx2 function isoform-dependently in postnatal bone development. |
Q35636978 | Central Role of Core Binding Factor β2 in Mucosa-Associated Lymphoid Tissue Organogenesis in Mouse |
Q35022641 | Cilia involvement in patterning and maintenance of the skeleton |
Q35634081 | Cilia-like structures and polycystin-1 in osteoblasts/osteocytes and associated abnormalities in skeletogenesis and Runx2 expression. |
Q38858036 | Cleidocranial dysplasia and RUNX2-clinical phenotype-genotype correlation |
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Q33569659 | Conditional disruption of Pkd1 in osteoblasts results in osteopenia due to direct impairment of bone formation. |
Q34430664 | Conditional mesenchymal disruption of pkd1 results in osteopenia and polycystic kidney disease. |
Q36279535 | Core binding factor beta (Cbfβ) controls the balance of chondrocyte proliferation and differentiation by upregulating Indian hedgehog (Ihh) expression and inhibiting parathyroid hormone-related protein receptor (PPR) expression in postnatal cartilag |
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Q35990019 | Disruption of Kif3a in osteoblasts results in defective bone formation and osteopenia |
Q28588130 | Dlx5 Is a cell autonomous regulator of chondrocyte hypertrophy in mice and functionally substitutes for Dlx6 during endochondral ossification |
Q38321841 | Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter |
Q41874349 | Dlx5, a positive regulator of osteoblastogenesis, is essential for osteoblast-osteoclast coupling. |
Q37396635 | Dose-dependent effects of Runx2 on bone development. |
Q33636577 | Down-regulation of type I Runx2 mediated by dexamethasone is required for 3T3-L1 adipogenesis |
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Q35737205 | Ectopic expression of SOX9 in osteoblasts alters bone mechanical properties. |
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Q28476413 | Kif3a deficiency reverses the skeletal abnormalities in Pkd1 deficient mice by restoring the balance between osteogenesis and adipogenesis |
Q92377245 | Molecular Mechanism of Runx2-Dependent Bone Development |
Q28542439 | Osteoblast-specific deletion of Pkd2 leads to low-turnover osteopenia and reduced bone marrow adiposity |
Q28541582 | Osteocyte-specific deletion of Fgfr1 suppresses FGF23 |
Q90729095 | Osteoporosis: Mechanism, Molecular Target, and Current Status on Drug Development |
Q35004670 | Polyalanine repeat polymorphism in RUNX2 is associated with site-specific fracture in post-menopausal females |
Q36585580 | Polycystin-1 regulates skeletogenesis through stimulation of the osteoblast-specific transcription factor RUNX2-II. |
Q37623787 | Protein kinase inhibitor SU6668 attenuates positive regulation of Gli proteins in cancer and multipotent progenitor cells |
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Q33787937 | Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells |
Q36616577 | Runx2 and dental development |
Q35314247 | Runx2 protein expression utilizes the Runx2 P1 promoter to establish osteoprogenitor cell number for normal bone formation |
Q48194394 | Runx2, an inducer of osteoblast and chondrocyte differentiation. |
Q34227055 | Runx2-I isoform contributes to fetal bone formation even in the absence of specific N-terminal amino acids |
Q34333682 | Selective Runx2-II deficiency leads to low-turnover osteopenia in adult mice |
Q50896849 | Systems level analysis of osteoclastogenesis reveals intrinsic and extrinsic regulatory interactions. |
Q28588867 | Targeted disruption of the Mn1 oncogene results in severe defects in development of membranous bones of the cranial skeleton. |
Q37667523 | The differentially DNA-methylated region responsible for expression of runt-related transcription factor 2. |
Q38903594 | Thymosin beta 4 is associated with RUNX2 expression through the Smad and Akt signaling pathways in mouse dental epithelial cells |
Q35895390 | Transforming growth factor beta signaling in adult cardiovascular diseases and repair. |
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