runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins

scientific article

runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins is …
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scholarly articleQ13442814

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P356DOI10.1128/MCB.21.8.2891-2905.2001
P932PMC publication ID86918
P698PubMed publication ID11283267
P5875ResearchGate publication ID12050828

P50authorLouis Charles GerstenfeldQ67658704
P2093author name stringG S Stein
J L Stein
J B Lian
A Javed
B O Jasanya
G L Barnes
L Gerstenfeld
P2860cites workHuman homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteinsQ24324093
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone developmentQ28119185
A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemiaQ28141676
Osf2/Cbfa1: a transcriptional activator of osteoblast differentiationQ28240596
The Groucho/transducin-like enhancer of split transcriptional repressors interact with the genetically defined amino-terminal silencing domain of histone H3Q28251560
Msx-2/Hox 8.1: a transcriptional regulator of the rat osteocalcin promoterQ28569869
A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila developmentQ28609065
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblastsQ29547605
Characterization of a cDNA for chicken osteopontin: expression during bone development, osteoblast differentiation, and tissue distributionQ33518738
Cooperation among multiple transcription factors is required for access to minimal T-cell receptor alpha-enhancer chromatin in vivoQ33773382
Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with CbfbetaQ33774997
Analysis of the growth factor requirements for stimulation of WI-38 cells after extended periods of density-dependent growth arrestQ69500069
Structural analysis and characterization of tissue and hormonal responsive expression of the avian bone sialoprotein (BSP) geneQ73029433
Crystal structure of the nuclear matrix targeting signal of the transcription factor acute myelogenous leukemia-1/polyoma enhancer-binding protein 2alphaB/core binding factor alpha2Q73176121
Sequential expression of bone matrix proteins during rat calvaria osteoblast differentiation and bone nodule formation in vitroQ73248753
CBFa(AML/PEBP2)-related elements in the TGF-beta type I receptor promoter and expression with osteoblast differentiationQ74530821
Kinetics of osteoprogenitor proliferation and osteoblast differentiation in vitroQ78108341
Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiationQ33888879
Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF(alpha)/AML/PEBP2(alpha)) dependent activation of tissue-specific gene transcriptionQ33902979
Multiple Cbfa/AML sites in the rat osteocalcin promoter are required for basal and vitamin D-responsive transcription and contribute to chromatin organization.Q33960022
Transcriptional control of the tissue-specific, developmentally regulated osteocalcin gene requires a binding motif for the Msx family of homeodomain proteinsQ36010554
Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineageQ36235105
Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factorsQ36239602
Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineagesQ36256208
Nucleation of hydroxyapatite by bone sialoproteinQ36539546
Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogeneQ36552332
Characterization of an Avian Bone Sialoprotein (BSP) cDNA: Comparisons to Mammalian BSP and Identification of Conserved Structural DomainsQ36687322
Characterization of the human bone sialoprotein (BSP) gene and its promoter sequenceQ36737358
An AML-1 consensus sequence binds an osteoblast-specific complex and transcriptionally activates the osteocalcin geneQ37610593
Identification of a minimal sequence of the mouse pro-alpha 1(I) collagen promoter that confers high-level osteoblast expression in transgenic mice and that binds a protein selectively present in osteoblastsQ37728143
A PEBP2 alpha/AML-1-related factor increases osteocalcin promoter activity through its binding to an osteoblast-specific cis-acting elementQ38287692
The tissue-specific nuclear matrix protein, NMP-2, is a member of the AML/CBF/PEBP2/runt domain transcription factor family: interactions with the osteocalcin gene promoterQ38290497
Transient upregulation of CBFA1 in response to bone morphogenetic protein-2 and transforming growth factor beta1 in C2C12 myogenic cells coincides with suppression of the myogenic phenotype but is not sufficient for osteoblast differentiationQ38326843
Cloning of a 2.5 kb murine bone sialoprotein promoter fragment and functional analysis of putative Osf2 binding sitesQ38327862
Characteristics of vitamin D3 receptor (VDR) binding to the vitamin D response element (VDRE) in rat bone sialoprotein gene promoterQ38338556
Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complexQ38344674
Bone tissue-specific transcription of the osteocalcin gene: role of an activator osteoblast-specific complex and suppressor hox proteins that bind the OC box.Q38358091
Osteopontin: a protein with diverse functions.Q40791476
Constitutive expression and regulation of collagenase-3 in human breast cancer cells.Q40868944
Identification of a homeodomain binding element in the bone sialoprotein gene promoter that is required for its osteoblast-selective expressionQ40883137
CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoterQ40986530
Attachment of osteoblastic cells to hydroxyapatite crystals by a synthetic peptide (Glu7-Pro-Arg-Gly-Asp-Thr) containing two functional sequences of bone sialoproteinQ41117709
The human bone sialoprotein gene contains an NF-E1/YY1 cis-acting sequence with putative regulatory activityQ41124536
AML-2 is a potential target for transcriptional regulation by the t(8;21) and t(12;21) fusion proteins in acute leukemiaQ41183963
Comparison of two phosphoproteins in chicken bone and their similarities to the mammalian bone proteins, osteopontin and bone sialoprotein IIQ41714227
Tissue specific and vitamin D responsive gene expression in bone.Q41737437
Bone matrix mRNA expression in differentiating fetal bovine osteoblastsQ42462360
Signal transduction pathways mediating parathyroid hormone stimulation of bone sialoprotein gene expression in osteoblastsQ42527537
Sulphation of secreted phosphoprotein I (SPPI, osteopontin) is associated with mineralized tissue formationQ46274469
Mineralization and the expression of matrix proteins during in vivo bone developmentQ46291989
Rat tibial osteoblasts III: Propagation in vitro is accompanied by enhancement of osteoblast phenotypeQ46292507
Ectodermal patterning in the avian embryo: epidermis versus neural plate.Q52181918
Expression of cell growth and bone specific genes at single cell resolution during development of bone tissue-like organization in primary osteoblast cultures.Q52230731
Interactions between the bone matrix proteins osteopontin and bone sialoprotein and the osteoclast integrin alpha v beta 3 potentiate bone resorptionQ58085856
Trans-differentiation of hypertrophic chondrocytes into cells capable of producing a mineralized bone matrixQ67572851
Expression of bone sialoprotein (BSP) in developing human tissuesQ67892131
Identification and characterization of the major chicken bone phosphoprotein. Analysis of its synthesis by cultured embryonic chick osteoblastsQ68698684
A nonchromatographic assay for expression of the chloramphenicol acetyltransferase gene in eucaryotic cellsQ68733304
Expression of differentiated function by mineralizing cultures of chicken osteoblastsQ68822795
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)2891-2905
P577publication date2001-04-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titlerunt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins
P478volume21

Reverse relations

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