Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment

scientific article published on January 2014

Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4161/MABS.27226
P932PMC publication ID3929447
P698PubMed publication ID24253107

P50authorChristopher J LangmeadQ88424187
Stephen J. HillQ37828928
Jeanette WoolardQ44377018
Fiona H. MarshallQ53997636
P2093author name stringAli Jazayeri
Andrei Zhukov
Malcolm Weir
Markus Koglin
Catherine J Hutchings
Gabriella Cseke
Greg Osborne
Jahnavi Pandya-Pathak
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P433issue1
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
P304page(s)246-261
P577publication date2014-01-01
P1433published inMonoclonal AntibodiesQ6714645
P1476titleMonoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment
P478volume6

Reverse relations

cites work (P2860)
Q47441641A monoclonal antibody raised against a thermo-stabilised β1-adrenoceptor interacts with extracellular loop 2 and acts as a negative allosteric modulator of a sub-set of β1-adrenoceptors expressed in stable cell lines.
Q54203028A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies.
Q36213478Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1
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Q35933820Antibody Engineering & Therapeutics, the annual meeting of The Antibody Society December 7-10, 2015, San Diego, CA, USA.
Q26781607Challenges and opportunities for non-antibody scaffold drugs
Q37141597DNA immunization combined with scFv phage display identifies antagonistic GCGR specific antibodies and reveals new epitopes on the small extracellular loops
Q38282832Discovery of functional antibodies targeting ion channels
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Q94445335Rapid identification of highly potent human anti-GPCR antagonist monoclonal antibodies
Q95282452Unmasking features of the auto-epitope essential for β1 -adrenoceptor activation by autoantibodies in chronic heart failure

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