| scholarly article | Q13442814 |
| P50 | author | Belinda Duchêne | Q53225077 |
| Nicolas Jonckheere | Q53225113 | ||
| Isabelle Van Seuningen | Q58158912 | ||
| P2093 | author name string | M Hebbar | |
| E Leteurtre | |||
| N Skrypek | |||
| P2860 | cites work | Global cancer statistics | Q22241238 |
| Human equilibrative nucleoside transporter 1 levels predict response to gemcitabine in patients with pancreatic cancer. | Q27863396 | ||
| The membrane mucin Muc4 inhibits apoptosis induced by multiple insults via ErbB2-dependent and ErbB2-independent mechanisms | Q28566287 | ||
| FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer | Q29547638 | ||
| The K protein domain that recruits the interleukin 1-responsive K protein kinase lies adjacent to a cluster of c-Src and Vav SH3-binding sites. Implications that K protein acts as a docking platform | Q30192947 | ||
| Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine. | Q33238550 | ||
| Prognostic significance of apoptosis regulators in breast cancer. | Q33872962 | ||
| The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways | Q34185812 | ||
| Nucleoside transporter profiles in human pancreatic cancer cells: role of hCNT1 in 2',2'-difluorodeoxycytidine- induced cytotoxicity. | Q34272622 | ||
| MUC4 mucin-induced epithelial to mesenchymal transition: a novel mechanism for metastasis of human ovarian cancer cells. | Q34423709 | ||
| CNT1 expression influences proliferation and chemosensitivity in drug-resistant pancreatic cancer cells | Q34621614 | ||
| Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy | Q35567292 | ||
| The MRP family of drug efflux pumps | Q35567296 | ||
| Pancreatic adenocarcinoma: new strategies for success | Q37198628 | ||
| Tumour growth and resistance to gemcitabine of pancreatic cancer cells are decreased by AP-2alpha overexpression. | Q37330687 | ||
| Pancreatic cancer cells resistance to gemcitabine: the role of MUC4 mucin | Q37400545 | ||
| The ribonucleotide reductase large subunit (RRM1) as a predictive factor in patients with cancer. | Q37821595 | ||
| Mucins and pancreatic cancer. | Q38166583 | ||
| Sequence of the 5'-flanking region and promoter activity of the human mucin gene MUC5B in different phenotypes of colon cancer cells | Q38311644 | ||
| ATP-binding cassette superfamily transporter gene expression in human primary ovarian carcinoma. | Q38359967 | ||
| Interdependence of gemcitabine treatment, transporter expression, and resistance in human pancreatic carcinoma cells. | Q39658359 | ||
| Downregulation of nuclear factor-kappaB p65 subunit by small interfering RNA synergizes with gemcitabine to inhibit the growth of pancreatic cancer | Q39780870 | ||
| Involvement of drug transporters in the synergistic action of FOLFOX combination chemotherapy | Q39822552 | ||
| Mucin overexpression limits the effectiveness of 5-FU by reducing intracellular drug uptake and antineoplastic drug effects in pancreatic tumours | Q39910541 | ||
| Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products. | Q40144497 | ||
| MUC4 mucin potentiates pancreatic tumor cell proliferation, survival, and invasive properties and interferes with its interaction to extracellular matrix proteins. | Q40150208 | ||
| Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1alpha. | Q40220702 | ||
| Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer | Q40365695 | ||
| Human multidrug resistance associated protein 4 confers resistance to camptothecins. | Q40379793 | ||
| The murine Muc2 mucin gene is transcriptionally regulated by the zinc-finger GATA-4 transcription factor in intestinal cells | Q40492838 | ||
| Transcriptional regulation of human mucin MUC4 by bile acids in oesophageal cancer cells is promoter-dependent and involves activation of the phosphatidylinositol 3-kinase signalling pathway | Q40622178 | ||
| Tumor uptake and elimination of 2',2'-difluoro-2'-deoxycytidine (gemcitabine) after deoxycytidine kinase gene transfer: correlation with in vivo tumor response. | Q40682173 | ||
| Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death | Q42441668 | ||
| Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine | Q42827290 | ||
| Analysis of the MRP4 drug resistance profile in transfected NIH3T3 cells | Q42833544 | ||
| Deoxycitidine kinase is associated with prolonged survival after adjuvant gemcitabine for resected pancreatic adenocarcinoma | Q42952825 | ||
| Dihydroartemisinin inactivates NF-kappaB and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo. | Q43170838 | ||
| Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: overcoming cellular barriers for therapeutic gain | Q43199364 | ||
| Association between expression of the MRP3 gene and exposure to platinum drugs in lung cancer | Q43690852 | ||
| Acquired resistance of pancreatic cancer cells towards 5-Fluorouracil and gemcitabine is associated with altered expression of apoptosis-regulating genes | Q44077436 | ||
| Multidrug resistance correlates with overexpression of Muc4 but inversely with P-glycoprotein and multidrug resistance related protein in transfected human melanoma cells | Q44430754 | ||
| Human equilibrative nucleoside transporter 1 and human concentrative nucleoside transporter 3 predict survival after adjuvant gemcitabine therapy in resected pancreatic adenocarcinoma | Q46076287 | ||
| A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-beta in pancreatic carcinogenesis. | Q47376029 | ||
| Pancreatic Cancer | Q54135367 | ||
| Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma | Q60975951 | ||
| Potentiation of metastasis by cell surface sialomucin complex (rat MUC4), a multifunctional anti-adhesive glycoprotein | Q74081704 | ||
| MUC4 expression increases progressively in pancreatic intraepithelial neoplasia | Q74385664 | ||
| bcl-2/bax ratio as a predictive marker for therapeutic response to radiotherapy in patients with prostate cancer | Q77628637 | ||
| The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells | Q77904111 | ||
| P433 | issue | 13 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | pancreatic cancer | Q212961 |
| P304 | page(s) | 1714-1723 | |
| P577 | publication date | 2012-05-14 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family | |
| P478 | volume | 32 |
| Q90419746 | A Humanized Yeast Phenomic Model of Deoxycytidine Kinase to Predict Genetic Buffering of Nucleoside Analog Cytotoxicity |
| Q60915898 | Advancement of NF-κB Signaling Pathway: A Novel Target in Pancreatic Cancer |
| Q28484288 | Algorithmic modeling quantifies the complementary contribution of metabolic inhibitions to gemcitabine efficacy |
| Q37706759 | Cell membrane-anchored MUC4 promotes tumorigenicity in epithelial carcinomas |
| Q90084765 | Chemogenomic study of gemcitabine using Saccharomyces cerevisiae as model cell-molecular insights about chemoresistance |
| Q90080192 | Chemoresistance in Pancreatic Cancer |
| Q90376957 | Clinical candidate and genistein analogue AXP107-11 has chemoenhancing functions in pancreatic adenocarcinoma through G protein-coupled estrogen receptor signaling |
| Q86761408 | Comment on: Functional MUC4 suppress epithelial-mesenchymal transition in lung adenocarcinoma metastasis. Gao L, Liu J, Zhang B, Zhang H, Wang D, Zhang T, Liu Y, Wang C. Tumour Biol. 2013, in press |
| Q98895876 | Concentrative Nucleoside Transporter 3 Is Located on Microvilli of Vaginal Epithelial Cells |
| Q38737073 | DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells |
| Q38662233 | Distal bile duct carcinomas and pancreatic ductal adenocarcinomas: postulating a common tumor entity |
| Q38769440 | Downregulation of STAT3/NF-κB potentiates gemcitabine activity in pancreatic cancer cells |
| Q45062589 | Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer |
| Q55000681 | Electroporation with Cisplatin against Metastatic Pancreatic Cancer: In Vitro Study on Human Primary Cell Culture. |
| Q36342657 | Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine |
| Q41592725 | Galeterone and its analogs inhibit Mnk-eIF4E axis, synergize with gemcitabine, impede pancreatic cancer cell migration, invasion and proliferation and inhibit tumor growth in mice |
| Q41709484 | Gemcitabine-induced heparanase promotes aggressiveness of pancreatic cancer cells via activating EGFR signaling. |
| Q24273350 | How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion |
| Q39175499 | Immunotherapy in pancreatic cancer treatment: a new frontier |
| Q36246425 | Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma |
| Q58711412 | Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas |
| Q51107700 | Low MUC4 expression is associated with survival benefit in patients with resectable pancreatic cancer receiving adjuvant gemcitabine. |
| Q38688917 | MUC4 mucin- a therapeutic target for pancreatic ductal adenocarcinoma. |
| Q91272239 | MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis |
| Q36545296 | MUC4-promoted neural invasion is mediated by the axon guidance factor Netrin-1 in PDAC |
| Q42554135 | MicroRNA Profile to Predict Gemcitabine Resistance in Bladder Carcinoma Cell Lines |
| Q50465411 | Molecular Pathways: Mucins and Drug Delivery in Cancer. |
| Q38767655 | Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 Knockdown |
| Q39410445 | Mucins in pancreatic cancer: biological role, implications in carcinogenesis and applications in diagnosis and therapy |
| Q91657956 | NF-κB/Rel Transcription Factors in Pancreatic Cancer: Focusing on RelA, c-Rel, and RelB |
| Q37705843 | NIDO, AMOP and vWD domains of MUC4 play synergic role in MUC4 mediated signaling |
| Q49387560 | Overcoming tumor cell chemoresistance using nanoparticles: lysosomes are beneficial for (stearoyl) gemcitabine-incorporated solid lipid nanoparticles |
| Q35223880 | Overexpression of chemokine receptor CXCR2 and ligand CXCL7 in liver metastases from colon cancer is correlated to shorter disease-free and overall survival |
| Q47135556 | Pancreatic Cancer Chemoresistance to Gemcitabine |
| Q38262107 | Persistent hepatitis C virus infection impairs ribavirin antiviral activity through clathrin-mediated trafficking of equilibrative nucleoside transporter 1. |
| Q28817908 | Physical and chemical characteristics of mucin secreted by pseudomyxoma peritonei (PMP) |
| Q47791593 | Physicochemical properties of mucus and their impact on transmucosal drug delivery |
| Q90609157 | Prognostic and predictive factors in pancreatic cancer |
| Q35679558 | RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavage |
| Q64066827 | Role of hepatocyte nuclear factor 4 alpha in cell proliferation and gemcitabine resistance in pancreatic adenocarcinoma |
| Q90672672 | TGF-βRII Knock-down in Pancreatic Cancer Cells Promotes Tumor Growth and Gemcitabine Resistance. Importance of STAT3 Phosphorylation on S727 |
| Q35741633 | Targeting EGF-receptor(s) - STAT1 axis attenuates tumor growth and metastasis through downregulation of MUC4 mucin in human pancreatic cancer |
| Q41824598 | Targeting MUC4 in pancreatic cancer: miRNAs. |
| Q100750176 | Targeting interleukin-17 receptor B enhances gemcitabine sensitivity through downregulation of mucins in pancreatic cancer |
| Q92463715 | The challenge of drug resistance in pancreatic ductal adenocarcinoma: a current overview |
| Q35793641 | The oncogenic receptor ErbB2 modulates gemcitabine and irinotecan/SN-38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrug-resistance associated protein MRP-2. |
| Q36994566 | The role of the AMOP domain in MUC4/Y-promoted tumour angiogenesis and metastasis in pancreatic cancer |
| Q48265598 | Vascular-Associated Muc4/Vwf Co-Localization in Human Conjunctival Malignant Melanoma Specimens-Tumor Metastasis by Migration? |
| Q39017335 | miR-219-1-3p is a negative regulator of the mucin MUC4 expression and is a tumor suppressor in pancreatic cancer. |
| Q58760423 | p21-activated kinase signalling in pancreatic cancer: New insights into tumour biology and immune modulation |
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