Opioids and HIV/HCV infection

scientific article published on 14 July 2011

Opioids and HIV/HCV infection is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1007/S11481-011-9296-1
P932PMC publication ID3937260
P698PubMed publication ID21755286

P2093author name stringXu Wang
Ting Zhang
Wen-Zhe Ho
P2860cites workCD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tractQ22242965
Microbial translocation is a cause of systemic immune activation in chronic HIV infectionQ22251054
Role of microglia in central nervous system infectionsQ24563024
Morphine Withdrawal Enhances Hepatitis C Virus Replicon ExpressionQ27477516
Morphine Enhances Hepatitis C Virus (HCV) Replicon ExpressionQ27478396
Coinfection with Hepatitis C Virus and Human Immunodeficiency Virus: Virological, Immunological, and Clinical OutcomesQ27488883
Upregulation of SOCS-3 and PIAS-3 Impairs IL-12-Mediated Interferon-Gamma Response in CD56+ T Cells in HCV-Infected Heroin UsersQ27491026
Hepatitis C virus infectionQ27861002
Determinants of viral clearance and persistence during acute hepatitis C virus infectionQ28131757
Hepatitis C in the HIV-Infected PersonQ28206126
Peginterferon Alfa-2a plus ribavirin for chronic hepatitis C virus infection in HIV-infected patientsQ28274666
Peginterferon Alfa-2a plus ribavirin versus interferon alfa-2a plus ribavirin for chronic hepatitis C in HIV-coinfected personsQ28274676
Morphine promotes the growth of HIV-1 in human peripheral blood mononuclear cell coculturesQ28330757
Morphine stimulates HIV replication in primary cultures of human Kupffer cellsQ28333195
Methadone enhances human immunodeficiency virus infection of human immune cellsQ28344125
Comparison of hepatitis C viral loads in patients with or without human immunodeficiency virusQ28367786
Morphine exacerbates HIV-1 Tat-induced cytokine production in astrocytes through convergent effects on [Ca(2+)](i), NF-kappaB trafficking and transcriptionQ28474433
The prevalence of hepatitis C virus infection in the United States, 1988 through 1994Q29620136
Investigating the influence of treatment philosophy on outcome of methadone maintenance.Q30417515
Emerging evidence of hepatitis C virus neuroinvasionQ31013540
Microbial translocation is associated with increased monocyte activation and dementia in AIDS patientsQ33346244
Natural history of hepatitis C virus infection in multitransfused hemophiliacs: effect of coinfection with human immunodeficiency virus. The Multicenter Hemophilia Cohort Study.Q33492170
Methylnaltrexone antagonizes opioid-mediated enhancement of HIV infection of human blood mononuclear phagocytesQ33593875
Morphine Enhances HIV Infection of Neonatal MacrophagesQ33669599
Morphine enhances HIV infection of human blood mononuclear phagocytes through modulation of beta-chemokines and CCR5 receptorQ33683180
Involvement of Fas system-mediated apoptosis in pathogenesis of viral hepatitisQ33801352
Effectiveness and tolerability of combination treatment of chronic hepatitis C in illicit drug users: meta-analysis of prospective studiesQ33819160
Hepatitis C virus regulates transforming growth factor beta1 production through the generation of reactive oxygen species in a nuclear factor kappaB-dependent mannerQ33905849
Effects of HCV treatment on cytokine expression during HCV/HIV coinfectionQ33961483
High rate of spontaneous negativity for hepatitis C virus RNA after establishment of chronic infection in Alaska NativesQ33993892
Detection and function of opioid receptors on cells from the immune systemQ33998561
Human immunodeficiency virus seroconversion among intravenous drug users in- and out-of-treatment: an 18-month prospective follow-upQ34061372
The impact of hepatitis C virus infection on methadone maintenance treatment.Q34077006
Opioids, opioid receptors, and the immune responseQ34179298
The liver as an immune organQ34261853
Utilization of on-site primary care services by HIV-seropositive and seronegative drug users in a methadone maintenance program.Q34453357
HIV and HCV cooperatively promote hepatic fibrogenesis via induction of reactive oxygen species and NFkappaBQ34509401
Enhancement of mice susceptibility to infection with Listeria monocytogenes by the treatment of morphineQ34569281
HIV infection and the gastrointestinal immune systemQ34601874
The mucosal barrier and immune activation in HIV pathogenesisQ34606638
Seroprevalence of hepatitis C markers among intravenous drug users in western European countries: a systematic reviewQ34637206
Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytesQ34695803
HIV infection increases HCV-induced hepatocyte apoptosisQ34699457
Inhibition of anti-HIV microRNA expression: a mechanism for opioid-mediated enhancement of HIV infection of monocytesQ34756351
Death receptor-mediated apoptosis and the liverQ34783540
HIV-1 Tat and opiate-induced changes in astrocytes promote chemotaxis of microglia through the expression of MCP-1 and alternative chemokinesQ34797566
Hepatitis C virus and human immunodeficiency virus-1 co-infection in former heroin addicts in methadone maintenance treatmentQ34893342
Microbial Infections, Immunomodulation, and Drugs of AbuseQ34926928
Opioids, immunology, and host defenses of intravenous drug abusersQ34950453
Morphine withdrawal lowers host defense to enteric bacteria: spontaneous sepsis and increased sensitivity to oral Salmonella enterica serovar Typhimurium infectionQ35073676
Immunoregulatory effects of morphine on human lymphocytesQ35229000
Opioid-mediated suppression of interferon-gamma production by cultured peripheral blood mononuclear cellsQ35578985
Impact of human immunodeficiency virus (HIV) infection on the progression of liver fibrosis in hepatitis C virus infected patientsQ35595809
Heroin-Induces Differential Protein Expression by Normal Human Astrocytes (NHA).Q35599877
An in vitro model of morphine withdrawal manifests the enhancing effect on human immunodeficiency virus infection of human T lymphocytes through the induction of substance P.Q35607410
Viral hepatitis C.Q35617324
Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesiaQ35677224
Toll-like receptor expression and activation in astroglia: differential regulation by HIV-1 Tat, gp120, and morphine.Q35779664
Treatment of chronic hepatitis C in patients with drug dependence: time to change the rules?Q35866175
Guidelines for the treatment of hepatitis C virus infection in injection drug users: status quo in the European Union countries.Q36071315
Opioids and the progression of simian AIDS.Q36071748
Methadone and buprenorphine maintenance therapies for patients with hepatitis C virus infected after intravenous drug use.Q36099168
Pulmonary complications of intravenous drug misuse. 2. Infective and HIV related complicationsQ36235474
The role of substance abuse in HIV disease progression: reconciling differences from laboratory and epidemiologic investigations.Q36249104
HIV disease: fallout from a mucosal catastrophe?Q36398125
The unenlarged lymph nodes of HIV-1-infected, asymptomatic patients with high CD4 T cell counts are sites for virus replication and CD4 T cell proliferation. The impact of highly active antiretroviral therapyQ36400457
Interactions of opioid and chemokine receptors: oligomerization of mu, kappa, and delta with CCR5 on immune cellsQ40692753
Morphine regulates gene expression of alpha- and beta-chemokines and their receptors on astroglial cells via the opioid mu receptorQ40702376
Morphine promotes simian acquired immunodeficiency syndrome virus replication in monkey peripheral mononuclear cells: induction of CC chemokine receptor 5 expression for virus entryQ40722078
Methadone induces CCR5 and promotes AIDS virus infectionQ40730523
Enhancement of HIV-1 replication by opiates and cocaine: the cytokine connectionQ40778881
Consequences of opiate-dependency in a monkey model of AIDS.Q40778898
The medical status of methadone maintenance patients in treatment for 11-18 yearsQ40791224
Morphine induces gene expression of CCR5 in human CEMx174 lymphocytesQ40869414
Tuberculosis in drug usersQ40962666
Natural killer cell activity and lymphocyte subsets in parenteral heroin abusers and long-term methadone maintenance patientsQ41326260
SIV mutations detected in morphine-treated Macaca mulatta following SIVmac239 infectionQ41398130
Increased replication of simian immunodeficiency virus in CEM x174 cells by morphine sulfateQ41526207
Patients co-infected with human immunodeficiency virus and hepatitis C virus demonstrate higher levels of hepatic HCV RNA.Q41710040
Lethality of morphine in mice infected with Toxoplasma gondii.Q41815651
Morphine negatively regulates interferon-gamma promoter activity in activated murine T cells through two distinct cyclic AMP-dependent pathwaysQ42169348
Factors associated with hepatitis C virus infection in injection and noninjection drug users in ItalyQ42602410
Irish injecting drug users and hepatitis C: the importance of the social context of injecting.Q42639237
Hepatitis C in methadone maintenance patients: prevalence and public policy implicationsQ42646672
Hepatitis C seroprevalence amongst injecting drug users attending a methadone programme.Q42676897
Prevalence and incidence of hepatitis C virus infection among young adult injection drug usersQ42680870
Effect of human immunodeficiency virus infection on hepatitis C virus infection in hemophiliacsQ42977231
A prospective controlled study of interferon-based therapy of chronic hepatitis C in patients on methadone maintenanceQ42986145
Evidence that both HIV and HIV-induced immunodeficiency enhance HCV replication among HCV seroconvertersQ42988172
Retrospective analysis of the impact of HIV infection and alcohol use on chronic hepatitis C in a large cohort of drug users.Q42989119
Unscrambling hepatitis C virus-host interactionsQ42994469
Hepatitis C Virus prevalence among patients infected with Human Immunodeficiency Virus: a cross-sectional analysis of the US adult AIDS Clinical Trials GroupQ43036483
Hepatitis C Virus Infection and Progression of Infection Due to Human Immunodeficiency VirusQ43038628
Morphine inhibits intrahepatic interferon- alpha expression and enhances complete hepatitis C virus replicationQ43039725
Coinfection with hepatitis viruses and outcome of initial antiretroviral regimens in previously naive HIV-infected subjectsQ43040457
Progression of chronic hepatitis C to liver fibrosis and cirrhosis in patients coinfected with hepatitis C virus and human immunodeficiency virusQ43042290
A study of susceptibility of primary human Kupffer cells to hepatitis C virusQ43042430
High hepatitis C viraemia and impaired antibody response in patients coinfected with HIV.Q43047625
Opiates as potential cofactors in progression of HIV-1 infections to AIDS.Q43070988
Evidence for central opioid receptors in the immunomodulatory effects of morphine: review of potential mechanism(s) of actionQ43071003
Opiates and infectionQ43071007
CCR2 mediates increases in glial activation caused by exposure to HIV-1 Tat and opiatesQ43123425
Morphine inhibits mucosal antibody responses and TGF-beta mRNA in gut-associated lymphoid tissue following oral cholera toxin in miceQ43743324
The immunosuppressive effects of chronic morphine treatment are partially dependent on corticosterone and mediated by the mu-opioid receptor.Q43982576
Abrupt or precipitated withdrawal from morphine induces immunosuppressionQ44014891
Effect of Morphine on Resistance to InfectionQ44014937
Incidence of hepatitis C, hepatitis B and HIV infections among drug users in a methadone-maintenance programmeQ44042748
Morphine inhibition of lymphocyte activity is mediated by an opioid dependent mechanismQ44131663
Opioid detoxification with buprenorphine, clonidine, or methadone in hospitalized heroin-dependent patients with HIV infectionQ44340791
Assessment of the involvement of central nervous system and peripheral opioid receptors in the immunomodulatory effects of acute morphine treatment in rats.Q44341702
Selective inactivation of CCR5 and decreased infectivity of R5 HIV-1 strains mediated by opioid-induced heterologous desensitizationQ44342822
Opioid-mediated suppression of cultured peripheral blood mononuclear cell respiratory burst activityQ44347886
Moderate- vs high-dose methadone in the treatment of opioid dependence: a randomized trialQ44351590
Endomorphin-1 potentiates HIV-1 expression in human brain cell cultures: implication of an atypical mu-opioid receptorQ44351901
Pegylated IFN-alpha2b plus ribavirin as therapy for chronic hepatitis C in HIV-infected patientsQ44406911
Hepatitis C virus infection in injection drug users in Bavaria: risk factors for seropositivityQ44520992
Withdrawal from morphine in mice suppresses splenic macrophage function, cytokine production, and costimulatory moleculesQ44641628
Morphine induces sepsis in miceQ44644417
Cannabinoids and morphine differentially affect HIV-1 expression in CD4(+) lymphocyte and microglial cell culturesQ44740877
Permissivity of primary cultures of human Kupffer cells for HIV-1.Q44981195
Hepatitis C-related discrimination among heroin users in Sydney: drug user or hepatitis C discrimination?Q45072473
Does hepatitis C virus co-infection accelerate clinical and immunological evolution of HIV-infected patients?Q45142113
Morphine impairs host innate immune response and increases susceptibility to Streptococcus pneumoniae lung infectionQ45195944
Mechanisms of liver injury. III. Oxidative stress in the pathogenesis of hepatitis C virusQ36444289
Drug abuse, innate immunity and hepatitis C virusQ36577777
Morphine suppresses intracellular interferon-alpha expression in neuronal cellsQ36874006
Buprenorphine/naloxone treatment in primary care is associated with decreased human immunodeficiency virus risk behaviorsQ36984354
Effects of opioid tolerance and withdrawal on the immune systemQ37015416
Cellular microRNA expression correlates with susceptibility of monocytes/macrophages to HIV-1 infectionQ37066263
Successful treatment of chronic hepatitis C with pegylated interferon in combination with ribavirin in a methadone maintenance treatment programQ37216987
Opiate abuse, innate immunity, and bacterial infectious diseasesQ37287395
Hepatitis C treatment in patients with drug addiction: clinical management of interferon-alpha-associated psychiatric side effectsQ37561259
Modulation by morphine of viral set point in rhesus macaques infected with simian immunodeficiency virus and simian-human immunodeficiency virusQ37567921
Community-acquired pneumonia in a cohort of former injection drug users with and without human immunodeficiency virus infection: incidence, etiologies, and clinical aspectsQ37884772
μ-opioid modulation of HIV-1 coreceptor expressionand HIV-1 replicationQ38355088
gp120 modulates the biology of human hepatic stellate cells: a link between HIV infection and liver fibrogenesisQ38924171
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) colonization and infection in intravenous and inhalational opiate drug abusersQ38989707
Implications of methadone maintenance for theories of narcotic addictionQ39281451
Hepatitis C and Human Immunodeficiency Virus Envelope Proteins Cooperatively Induce Hepatocytic Apoptosis via an Innocent Bystander MechanismQ39281648
Risk factors for and knowledge of Mycobacterium tuberculosis infection among drug users in substance abuse treatmentQ39485422
The acquired immunodeficiency syndrome and intravenous drug abuseQ39557590
Hepatitis C and progression of HIV diseaseQ39607141
HIV increases HCV replication in a TGF-beta1-dependent manner.Q40004969
Morphine induces defects in early response of alveolar macrophages to Streptococcus pneumoniae by modulating TLR9-NF-kappa B signalingQ40010143
High incidence of hepatitis C virus reinfection in a cohort of injecting drug usersQ40037737
Modulation of the transforming growth factor-beta signal transduction pathway by hepatitis C virus nonstructural 5A proteinQ40331093
Morphine exacerbates HIV-1 viral protein gp120 induced modulation of chemokine gene expression in U373 astrocytoma cellsQ40397346
Hepatitis C virus-replicating hepatocytes induce fibrogenic activation of hepatic stellate cells.Q40398346
Morphine inhibits CD8+ T cell-mediated, noncytolytic, anti-HIV activity in latently infected immune cellsQ40401232
Injection drug use and human immunodeficiency virus infectionQ40405946
Human immunodeficiency virus type 1 in illicit-drug solutions used intravenously retains infectivityQ40437870
Outbreak of Acinetobacter baumannii bacteremia related to contaminated morphine used for patient-controlled analgesiaQ40439741
Correlates of hepatitis C virus infections among injection drug users.Q40453200
Keeping quiet: microRNAs in HIV-1 latencyQ45230810
Hepatitis C in the HIV (human immunodeficiency virus) Atlanta V.A. (Veterans Affairs Medical Center) Cohort Study (HAVACS): the effect of coinfection on survivalQ45334756
Chronic morphine exposure causes pronounced virus replication in cerebral compartment and accelerated onset of AIDS in SIV/SHIV-infected Indian rhesus macaquesQ45413931
Pathogenesis of HIV infection: what the virus spares is as important as what it destroysQ45419109
Increased hepatocyte fas expression and apoptosis in HIV and hepatitis C virus coinfectionQ45423509
Influence of hepatitis C virus infection on HIV-1 disease progression and response to highly active antiretroviral therapyQ45424761
Rapid transmission of hepatitis C virus among young injecting heroin users in Southern ChinaQ45654072
Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients. The Multivirc GroupQ45747079
The impact of chronic hepatitis C virus infection on HIV disease and progression in intravenous drug usersQ45752296
Methadone maintenance and hepatitis C virus infection among injecting drug usersQ45759328
Human immunodeficiency virus infection modifies the natural history of chronic parenterally-acquired hepatitis C with an unusually rapid progression to cirrhosisQ45763095
Effect of human immunodeficiency virus on hepatitis C virus infection among injecting drug usersQ45767660
Hepatitis C, hepatitis B, and human immunodeficiency virus infections among non-intravenous drug-using patients attending clinics for sexually transmitted diseasesQ45778719
Adherence to hepatitis C treatment in recovering heroin users maintained on methadoneQ46126021
Morphine-induced transactivation of HIV-1 LTR in human neuroblastoma cellsQ46159012
Morphine withdrawal sensitizes mice to lipopolysaccharide: elevated TNF-alpha and nitric oxide with decreased IL-12.Q46507475
Splenic macrophages and B cells mediate immunosuppression following abrupt withdrawal from morphineQ46735687
Effects of mu, kappa or delta opioids administered by pellet or pump on oral Salmonella infection and gastrointestinal transitQ46972445
Multiple ways that drug abuse might influence AIDS progression: clues from a monkey modelQ47245276
Morphine amplifies HIV-1 expression in chronically infected promonocytes cocultured with human brain cellsQ48164028
Morphine-induced decreases in in vivo antibody responsesQ48168615
Morphine synergizes with lipopolysaccharide in a chronic endotoxemia modelQ48220322
Efficacy and safety of peginterferon alfa-2a/ribavirin in methadone maintenance patients: randomized comparison of direct observed therapy and self-administration.Q50567817
In vitro studies of the effect of methadone on natural killer cell activity.Q52266427
Continued drug use and other cofactors for progression to AIDS among injecting drug users.Q52272224
Morphine stimulates phagocytosis of Mycobacterium tuberculosis by human microglial cells: involvement of a G protein-coupled opiate receptor.Q52274096
HIV transmission and the cost-effectiveness of methadone maintenance.Q52278638
Aggravation by morphine and D-aspartic acid of pyelonephritis induced by i. v. inoculation of staphylococcus aureus in ratsQ54391041
[Rate of infection by blood-borne viruses in active heroin users in 3 Spanish cities].Q55239548
Targets for human encoded microRNAs in HIV genesQ57076044
The Effect of Multiple Doses of Peginterferon alfa-2b on the Steady-State Pharmacokinetics of Methadone in Patients With Chronic Hepatitis C Undergoing Methadone Maintenance TherapyQ59488286
Factors associated with prevalent hepatitis C: differences among young adult injection drug users in lower and upper Manhattan, New York CityQ64129844
Interferon inhibition by narcotic analgesicsQ68653946
Suppression of human peripheral blood mononuclear cell function by methadone and morphineQ69328003
Upregulation of HIV-1 expression in cocultures of chronically infected promonocytes and human brain cells by dynorphinQ72045083
Human Kupffer cells infected with HIV-1 in vivoQ72221656
Suppression of peritoneal macrophage phagocytosis of Candida albicans by opioidsQ72622006
Immunosuppression by morphine is mediated by central pathwaysQ72664033
Drugs of abuse and infectious diseasesQ72815438
Incidence and prevalence of hepatitis C among clients of a Brisbane methadone clinic: factors influencing hepatitis C serostatusQ73320495
[Effect of heroin-containing substances on the infectivity of the human immunodeficiency virus type 1 in vitro]Q78776587
Illicit drug use and HIV-1 disease progression: a longitudinal study in the era of highly active antiretroviral therapyQ82177447
Probable deceleration of progression of Simian AIDS affected by opiate dependency: studies with a rhesus macaque/SIVsmm9 modelQ83298306
P433issue4
P921main subjectopioidQ427523
HIVQ15787
P304page(s)477-489
P577publication date2011-07-14
P1433published inJournal of Neuroimmune PharmacologyQ6295645
P1476titleOpioids and HIV/HCV infection
P478volume6

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