| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0168-8278(02)00209-X |
| P698 | PubMed publication ID | 12175638 |
| P50 | author | Gregory J Gores | Q91520926 |
| P2093 | author name string | Jung-Hwan Yoon | |
| P2860 | cites work | Caspase-10 is an initiator caspase in death receptor signaling | Q24291922 |
| The receptor for the cytotoxic ligand TRAIL | Q24310481 | ||
| Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors | Q24310559 | ||
| Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis | Q24310597 | ||
| Identification and characterization of a new member of the TNF family that induces apoptosis | Q24318423 | ||
| Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway | Q24320210 | ||
| Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family | Q24320301 | ||
| IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases | Q24533214 | ||
| FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis | Q24548247 | ||
| Hepatitis C virus core protein binds to the cytoplasmic domain of tumor necrosis factor (TNF) receptor 1 and enhances TNF-induced apoptosis | Q27469538 | ||
| Induction of tumour necrosis factor (TNF) receptor type p55 and p75 in patients with chronic hepatitis C virus (HCV) infection | Q27480421 | ||
| Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alpha | Q27485874 | ||
| Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8 | Q28189969 | ||
| The TNF and TNF receptor superfamilies: integrating mammalian biology | Q28203717 | ||
| KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene | Q28250929 | ||
| Death receptors: signaling and modulation | Q28280897 | ||
| Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family | Q28285445 | ||
| IAP family proteins--suppressors of apoptosis | Q28297514 | ||
| Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF | Q29615685 | ||
| The Bcl-2 protein family: arbiters of cell survival | Q29618158 | ||
| Two CD95 (APO-1/Fas) signaling pathways | Q29619631 | ||
| Tumor necrosis factor receptor and Fas signaling mechanisms. | Q33652491 | ||
| Expression and antitumor effects of TRAIL in human cholangiocarcinoma | Q74228232 | ||
| Hepatic failure and liver cell damage in acute Wilson's disease involve CD95 (APO-1/Fas) mediated apoptosis | Q74539672 | ||
| Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kappa B-independent, caspase-3-dependent pathway | Q74623251 | ||
| The central executioners of apoptosis: caspases or mitochondria? | Q77135310 | ||
| Recognizing death: the phagocytosis of apoptotic cells | Q77203130 | ||
| Inhibition of fas death signals by FLIPs | Q77485563 | ||
| Death receptors in liver biology and pathobiology | Q77716477 | ||
| Apoptosis and the liver: relevance for the hepato-biliary-pancreatic surgeon | Q77946446 | ||
| The alteration of Fas receptor and ligand system in hepatocellular carcinomas: how do hepatoma cells escape from the host immune surveillance in vivo? | Q78045245 | ||
| Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas. | Q33834255 | ||
| Induction of cell death in human immunodeficiency virus-infected macrophages and resting memory CD4 T cells by TRAIL/Apo2l | Q33849293 | ||
| Apoptosis and liver disease | Q33915807 | ||
| Corpse clearance defines the meaning of cell death | Q33922730 | ||
| Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity | Q34057782 | ||
| Tumor necrosis factor receptor-associated factor (TRAF) 2 and its role in TNF signaling. | Q34135071 | ||
| Heat shock proteins: endogenous modulators of apoptotic cell death | Q34340472 | ||
| Hepatic stellate cells express the low affinity nerve growth factor receptor p75 and undergo apoptosis in response to nerve growth factor stimulation | Q35810015 | ||
| Lethal effect of the anti-Fas antibody in mice | Q36696599 | ||
| Oxidative stress-mediated apoptosis of hepatocytes exposed to acute ethanol intoxication | Q36845181 | ||
| Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitment | Q39444883 | ||
| Role of metals in oxygen radical reactions | Q39502986 | ||
| Copper metabolism in primary biliary cirrhosis | Q40337785 | ||
| The CTL's kiss of death | Q40399827 | ||
| Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling. | Q40767950 | ||
| Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. | Q40789234 | ||
| X protein of hepatitis B virus inhibits Fas-mediated apoptosis and is associated with up-regulation of the SAPK/JNK pathway | Q40839488 | ||
| Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas. | Q40873008 | ||
| Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. | Q40975748 | ||
| Cytochrome P-4502E1: its physiological and pathological role | Q41441345 | ||
| Inhibition of cytochrome c release in Fas-mediated signaling pathway in transgenic mice induced to express hepatitis C viral proteins | Q43030664 | ||
| Novel tumor necrosis factor toxic effects. Pulmonary hemorrhage and severe hepatic dysfunction | Q43688712 | ||
| The bile acid glycochenodeoxycholate induces trail-receptor 2/DR5 expression and apoptosis. | Q43708594 | ||
| Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats | Q43720079 | ||
| Additive activation of hepatic NF-kappaB by ethanol and hepatitis B protein X (HBX) or HCV core protein: involvement of TNF-alpha receptor 1-independent and -dependent mechanisms | Q43771289 | ||
| The hepatitis B virus X protein abrogates Bcl-2-mediated protection against Fas apoptosis in the liver | Q45733889 | ||
| Caspase activation correlates with the degree of inflammatory liver injury in chronic hepatitis C virus infection | Q45735446 | ||
| Hepatitis B virus X protein protects against anti-Fas-mediated apoptosis in human liver cells by inducing NF-kappa B. | Q45739265 | ||
| Tumor necrosis factor receptors in patients with chronic hepatitis B virus infection | Q45786097 | ||
| Transformation-dependent susceptibility of rat hepatic stellate cells to apoptosis induced by soluble Fas ligand | Q47720301 | ||
| Raised plasma soluble Fas and Fas-ligand in alcoholic liver disease | Q47880492 | ||
| Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas. | Q50517174 | ||
| Fas (CD95, APO-1) antigen expression and function in murine liver endothelial cells: implications for the regulation of apoptosis in liver endothelial cells. | Q54073687 | ||
| Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor | Q58116796 | ||
| Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways | Q59050520 | ||
| Involvement of CD95 (Apo-1/Fas) ligand expressed by rat Kupffer cells in hepatic immunoregulation. | Q64942701 | ||
| Increased plasma tumor necrosis factor in severe alcoholic hepatitis | Q68785342 | ||
| Apoptosis: a new mechanism of endothelial and Kupffer cell killing | Q70971805 | ||
| Fas antigen expression in liver tissues of patients with chronic hepatitis B | Q71598487 | ||
| Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo | Q72567277 | ||
| Fas-mediated cholangiopathy in the murine model of graft versus host disease | Q73584922 | ||
| Hepatocyte apoptosis is a pathologic feature of human alcoholic hepatitis | Q73700066 | ||
| Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand | Q73766150 | ||
| Regulation of CD95 (APO-1/Fas) receptor and ligand expression by lipopolysaccharide and dexamethasone in parenchymal and nonparenchymal rat liver cells | Q74027176 | ||
| Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines | Q74228203 | ||
| P433 | issue | 3 | |
| P921 | main subject | apoptotic process | Q14599311 |
| P304 | page(s) | 400-410 | |
| P577 | publication date | 2002-09-01 | |
| P1433 | published in | Journal of Hepatology | Q15724402 |
| P1476 | title | Death receptor-mediated apoptosis and the liver | |
| P478 | volume | 37 |
| Q46592715 | A moderate reduction of Bcl-x(L) expression protects against tumorigenesis; however, it also increases susceptibility to tissue injury |
| Q37606997 | ATP11C targets basolateral bile salt transporter proteins in mouse central hepatocytes |
| Q37702692 | Aflatoxin B1 invokes apoptosis via death receptor pathway in hepatocytes |
| Q34337858 | An algorithm that predicts the viability and the yield of human hepatocytes isolated from remnant liver pieces obtained from liver resections. |
| Q47596048 | Anti-apoptotic therapeutic approaches in liver diseases: do they really make sense? |
| Q38932631 | Anti-proliferative effects of Siegesbeckia orientalis ethanol extract on human endometrial RL-95 cancer cells. |
| Q33938546 | Antiproliferative activity and induction of apoptotic by ethanolic extract of Alpinia galanga rhizhome in human breast carcinoma cell line |
| Q37403072 | Apoptosis and necrosis in the liver |
| Q34764471 | Apoptosis as a Mechanism for Liver Disease Progression |
| Q36160716 | Apoptosis: a mechanism of acute and chronic liver injury |
| Q35651666 | Apoptosis: the nexus of liver injury and fibrosis. |
| Q35851172 | Association between TRAIL expression on peripheral blood lymphocytes and liver damage in chronic hepatitis B |
| Q60048845 | Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways |
| Q39914977 | Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent |
| Q44569551 | Bile salt-induced hepatocyte apoptosis involves epidermal growth factor receptor-dependent CD95 tyrosine phosphorylation |
| Q40606705 | CD95-tyrosine nitration inhibits hyperosmotic and CD95 ligand-induced CD95 activation in rat hepatocytes |
| Q38676495 | Caspase 3 role and immunohistochemical expression in assessment of apoptosis as a feature of H1N1 vaccine-caused Drug-Induced Liver Injury (DILI). |
| Q81031073 | Caspase activation is associated with spontaneous recovery from acute liver failure |
| Q45416243 | Caspase activation is required for antiviral treatment response in chronic hepatitis C virus infection |
| Q37279896 | Cell death serum biomarkers are early predictors for survival in severe septic patients with hepatic dysfunction |
| Q64891843 | Chemically modified liposomes carrying TRAIL target activated hepatic stellate cells and ameliorate hepatic fibrosis in vitro and in vivo. |
| Q42181716 | Crocus sativus L. (saffron) stigma aqueous extract induces apoptosis in alveolar human lung cancer cells through caspase-dependent pathways activation |
| Q36312529 | Death by association: BH3 domain-only proteins and liver injury |
| Q35985526 | Dissection of the multiple mechanisms of TNF-alpha-induced apoptosis in liver injury. |
| Q35615736 | Effect of ethanol on pro-apoptotic mechanisms in polarized hepatic cells |
| Q36223960 | Effectors of alcohol-induced cell killing in Drosophila |
| Q40215232 | Ethanol-induced apoptosis in polarized hepatic cells possibly through regulation of the Fas pathway |
| Q40229255 | Eupatilin attenuates bile acid-induced hepatocyte apoptosis |
| Q91933437 | Expression profiling of key pathways in rat liver after a one-year feeding trial with transgenic maize MON810 |
| Q57066927 | Future Pharmacotherapy for Non-alcoholic Steatohepatitis (NASH): Review of Phase 2 and 3 Trials |
| Q40244126 | Glycyrrhizic acid inhibits apoptosis and fibrosis in carbon-tetrachloride-induced rat liver injury |
| Q38465111 | Glycyrrhizin attenuates HMGB1-induced hepatocyte apoptosis by inhibiting the p38-dependent mitochondrial pathway |
| Q35727465 | Growth inhibitory and chemo-sensitization effects of naringenin, a natural flavanone purified from Thymus vulgaris, on human breast and colorectal cancer |
| Q45489050 | HIV coinfection shortens the survival of patients with hepatitis C virus-related decompensated cirrhosis. |
| Q37527686 | Hepatitis C virus-host interactions: Etiopathogenesis and therapeutic strategies |
| Q73735584 | Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis |
| Q41197346 | Hepatoprotective Effect of Gallotannin-enriched Extract Isolated from Gall on Hydrogen Peroxide-induced Cytotoxicity in HepG2 Cells |
| Q35734470 | Histological assessment of cholestasis |
| Q35753015 | Hsp70 may protect cardiomyocytes from stress-induced injury by inhibiting Fas-mediated apoptosis |
| Q33223863 | Hypothermic maintenance of hepatocyte spheroids |
| Q39213616 | In vitro and in vivo protection of stellate cells from apoptosis by leptin |
| Q44125748 | Increased hepatotoxicity of tumor necrosis factor-related apoptosis-inducing ligand in diseased human liver |
| Q40936303 | Interferon-Mediated Cytokine Induction Determines Sustained Virus Control in Chronic Hepatitis C Virus Infection |
| Q43092106 | Is alanine aminotransferase level a surrogate biomarker of hepatic apoptosis in nonalcoholic fatty liver disease? |
| Q41663817 | Kupffer cells protect liver sinusoidal endothelial cells from Fas-dependent apoptosis in sepsis by down-regulating gp130. |
| Q30487320 | Liver progenitor cells fold up a cell monolayer into a double-layered structure during tubular morphogenesis |
| Q39036410 | Low concentration of ethanol induce apoptosis in HepG2 cells: role of various signal transduction pathways |
| Q35734498 | Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease |
| Q38000987 | Mechanisms of cell death in acute liver failure |
| Q34017604 | Medical treatment of cholestatic liver diseases: From pathobiology to pharmacological targets |
| Q92644256 | Modulations of Histone Deacetylase 2 Offer a Protective Effect through the Mitochondrial Apoptosis Pathway in Acute Liver Failure |
| Q33907429 | Molecular mechanisms of liver fibrosis in HIV/HCV coinfection |
| Q40635296 | Nature and mechanisms of hepatocyte apoptosis induced by D-galactosamine/lipopolysaccharide challenge in mice |
| Q49646757 | Neutralization of CD95 ligand protects the liver against ischemia-reperfusion injury and prevents acute liver failure |
| Q28566534 | Neutralization of IL-10 exacerbates cycloheximide-induced hepatocellular apoptosis and necrosis |
| Q37607856 | Opioids and HIV/HCV infection |
| Q43292661 | Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis |
| Q45299520 | Phosphatidylinositol 3-kinase-dependent signaling modulates taurochenodeoxycholic acid-induced liver injury and cholestasis in perfused rat livers |
| Q48113710 | Pre-clinical study of a TNFR1-targeted 18F probe for PET imaging of breast cancer |
| Q40602482 | Prevention of Fas-mediated hepatic failure by transferrin |
| Q84230884 | Primary biliary cirrhosis |
| Q45723485 | Primary human hepatocytes--a valuable tool for investigation of apoptosis and hepatitis B virus infection |
| Q34414424 | Protective effects of Antrodia cinnamomea against liver injury. |
| Q64137166 | Protective role of curcumin in ameliorating AFB-induced apoptosis via mitochondrial pathway in liver cells |
| Q28072789 | Questions and controversies: the role of necroptosis in liver disease |
| Q93087176 | Randomised clinical trial: emricasan versus placebo significantly decreases ALT and caspase 3/7 activation in subjects with non-alcoholic fatty liver disease |
| Q37121662 | Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. |
| Q40062007 | Serum levels of caspase-cleaved cytokeratin 18 (CK18-Asp396) predict severity of liver disease in chronic hepatitis B. |
| Q27488402 | Signal transduction pathways in liver and the influence of hepatitis C virus infection on their activities |
| Q42984798 | Steatosis and liver cell apoptosis in chronic hepatitis C: a mechanism for increased liver injury |
| Q40345193 | Sulfasalazine reduces bile acid induced apoptosis in human hepatoma cells and perfused rat livers |
| Q36943407 | TRAIL mediates liver injury by the innate immune system in the bile duct-ligated mouse |
| Q39669200 | The Caspase Inhibitor IDN-6556 Attenuates Hepatic Injury and Fibrosis in the Bile Duct Ligated Mouse |
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