Steatosis and liver cell apoptosis in chronic hepatitis C: a mechanism for increased liver injury

scientific article published on May 2004

Steatosis and liver cell apoptosis in chronic hepatitis C: a mechanism for increased liver injury is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/HEP.20179
P698PubMed publication ID15122751
P5875ResearchGate publication ID8582253

P50authorAndrew D. CloustonQ38548319
Elizabeth PowellQ42597946
P2093author name stringDavid M Purdie
Michelle M Richardson
Julie R Jonsson
Meagan J Walsh
Daina M Vanags
P2860cites workSingle-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitisQ29619627
Involvement of Fas system-mediated apoptosis in pathogenesis of viral hepatitisQ33801352
Nonalcoholic steatosis and steatohepatitis IV. Nonalcoholic fatty liver disease abnormalities in macrophage function and cytokinesQ34467338
Death receptor-mediated apoptosis and the liverQ34783540
Triglyceride accumulation protects against fatty acid-induced lipotoxicityQ34866329
Lipoapoptosis: its mechanism and its diseasesQ35047180
Apoptosis in hepatitis C virus infectionQ35091473
Effect of weight reduction on liver histology and biochemistry in patients with chronic hepatitis C.Q35594723
Worsening of steatosis is an independent factor of fibrosis progression in untreated patients with chronic hepatitis C and paired liver biopsies.Q35598407
Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expressionQ36266492
Classification of chronic viral hepatitis: a need for reassessmentQ37032966
TUNEL apoptotic cell detection in tissue sections: critical evaluation and improvementQ38472345
Hepatitis C virus core protein inhibits Fas- and tumor necrosis factor alpha-mediated apoptosis via NF-kappaB activationQ39594009
Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosis.Q39632325
Characterisation of the differences between hepatitis C virus genotype 3 and 1 glycoproteins.Q40645144
Hepatitis C virus core protein induces apoptosis and impairs cell-cycle regulation in stably transformed Chinese hamster ovary cellsQ40877562
Suppression of apoptotic cell death by hepatitis C virus core proteinQ41145136
In overweight patients with chronic hepatitis C, circulating insulin is associated with hepatic fibrosis: implications for therapy.Q42981587
Sensitization to Fas-mediated apoptosis by hepatitis C virus core proteinQ42982436
Liver cell apoptosis in chronic hepatitis C correlates with histological but not biochemical activity or serum HCV-RNA levelsQ42998514
Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3.Q42999424
Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesityQ43031928
Steatosis accelerates fibrosis development over time in hepatitis C virus genotype 3 infected patientsQ43041131
The mechanisms underlying hepatitis C virus genotype 3-mediated liver damageQ43047606
Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) for measurement of cytokine and growth factor mRNA expression with fluorogenic probes or SYBR Green I.Q43623003
Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.Q43972538
Steatosis in chronic hepatitis C: relative contributions of obesity, diabetes mellitus, and alcoholQ44116657
Caspase activation correlates with the degree of inflammatory liver injury in chronic hepatitis C virus infectionQ45735446
Obesity and its nurturing effect on hepatitis C.Q53919637
Detection of male DNA in the liver of female patients with primary biliary cirrhosisQ61895905
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitisQ73735584
Lymphocyte apoptosis and cell replacement in human liver allograftsQ74365724
Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kappa B-independent, caspase-3-dependent pathwayQ74623251
Fibrosis in chronic hepatitis C correlates significantly with body mass index and steatosisQ74645276
Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expressionQ79209033
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectsteatosisQ1365091
hepatitis CQ154869
apoptotic processQ14599311
chronic hepatitis CQ55779873
chronic hepatitisQ62019625
P304page(s)1230-1238
P577publication date2004-05-01
P1433published inHepatologyQ15724398
P1476titleSteatosis and liver cell apoptosis in chronic hepatitis C: a mechanism for increased liver injury
P478volume39

Reverse relations

cites work (P2860)
Q4027922817 Beta-estradiol prevents cytotoxicity from hydrophobic bile acids in HepG2 and WRL-68 cell cultures
Q26770432A Meta-Analysis of the Association Between the I148M Variant of Patatin-Like Phospholipase Domain Containing 3 Gene and the Presence of Chronic Hepatitis C
Q58697388A nonalcoholic fatty liver disease model in human induced pluripotent stem cell-derived hepatocytes, created by endoplasmic reticulum stress-induced steatosis
Q37050079Adiponectin and its receptors in chronic hepatitis B patients with steatosis in china
Q80867459An apoptosis biomarker goes to the HCV clinic
Q33909978Anti-apoptotic and antioxidant effect of leptin on CCl₄-induced acute liver injury in rats
Q27490338Apoptosis in animal models of virus-induced disease
Q36669223Beyond insulin resistance: Innate immunity in nonalcoholic steatohepatitis
Q28468601Biochemical mechanism underlying hypertriglyceridemia and hepatic steatosis/hepatomegaly induced by acute schisandrin B treatment in mice
Q37776184Cell Death and Fibrogenesis
Q35165949Changes in lipid metabolism in chronic hepatitis C.
Q38157936Chronic HCV infection and inflammation: Clinical impact on hepatic and extra-hepatic manifestations
Q35045338Correlation of serum leptin levels with anthropometric and metabolic parameters and biochemical liver function in Chinese patients with chronic hepatitis C virus infection
Q27482253Cre-estrogen receptor-mediated hepatitis C virus structural protein expression in mice
Q37903853Current understanding of insulin resistance in hepatitis C.
Q36967102Elevated serum CK18 levels in chronic hepatitis C patients are associated with advanced fibrosis but not steatosis.
Q27485351Exploring differences in response to treatment with peginterferon alpha 2a (40kD) and ribavirin in chronic hepatitis C between genotypes 2 and 3
Q42991520Fibrosis correlates with a ductular reaction in hepatitis C: roles of impaired replication, progenitor cells and steatosis
Q39302599Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell culture
Q34699457HIV infection increases HCV-induced hepatocyte apoptosis
Q42203551Hepatic expression of miR-122, miR-126, miR-136 and miR-181a and their correlation to histopathological and clinical characteristics of patients with hepatitis C.
Q36382231Hepatitis C -- identifying patients with progressive liver injury
Q41867049Hepatitis C Virus Infection Increases c-Jun N-Terminal Kinase (JNK) Phosphorylation and Accentuates Hepatocyte Lipoapoptosis.
Q36377276Hepatitis C and steatosis: a reappraisal
Q37386098Hepatitis C virus and glucose and lipid metabolism
Q24658049Hepatitis C virus and type 2 diabetes
Q36749431Hepatitis C virus infection--pathobiology and implications for new therapeutic options
Q36634377Histological assessment of non-alcoholic fatty liver disease
Q45363028IL-22 and non-ELR-CXC chemokine expression in chronic hepatitis B virus-infected liver
Q37852704IRS2 and PTP1B: Two opposite modulators of hepatic insulin signalling.
Q36490255Impact of obesity on treatment of chronic hepatitis C.
Q83846277Impact of patatin-like phospholipase-3 (rs738409 C>G) polymorphism on fibrosis progression and steatosis in chronic hepatitis C
Q88881039Insulin resistance and its consequences in chronic hepatitis C
Q37201550Insulin resistance and necroinflammation drives ductular reaction and epithelial-mesenchymal transition in chronic hepatitis C.
Q36160709Insulin resistance and steatosis in hepatitis C virus infection.
Q34074149Is There a Potential Role for Anti-tumor Necrosis Factor Therapy in Patients with Human Immunodeficiency Virus?
Q40092587Lack of Fas antagonism by Met in human fatty liver disease
Q38008400Mechanisms and biomarkers of apoptosis in liver disease and fibrosis
Q33866272Mechanisms and significance of liver steatosis in hepatitis C virus infection
Q42123455Melatonin in the regulation of liver steatosis following prenatal glucocorticoid exposure.
Q27011787Metabolic factors and chronic hepatitis C: a complex interplay
Q40122130Microarray analyses and molecular profiling of steatosis induction in immortalized human hepatocytes
Q45325177Modulation of Cell Death Pathways by Hepatitis C Virus Proteins in Huh7.5 Hepatoma Cells.
Q45369635No evidence of the unfolded protein response in patients with chronic hepatitis C virus infection
Q27478313Non-response to antiviral therapy is associated with obesity and increased hepatic expression of suppressor of cytokine signalling 3 (SOCS-3) in patients with chronic hepatitis C, viral genotype 1
Q61895898Obesity and steatosis influence serum and hepatic inflammatory markers in chronic hepatitis C
Q40312537Paradoxical effects of short- and long-term interleukin-6 exposure on liver injury and repair.
Q34860648Parenchymal expression of CD40 exacerbates adenovirus-induced hepatitis in mice.
Q27022707Pathophysiology of insulin resistance and steatosis in patients with chronic viral hepatitis
Q48591916Quantification of portal-bridging fibrosis area more accurately reflects fibrosis stage and liver stiffness than whole fibrosis or perisinusoidal fibrosis areas in chronic hepatitis C.
Q36286323Review article: an unexpected virus-host interaction--the hepatitis C virus-diabetes link
Q42870806Steatosis as a co-factor in chronic liver diseases
Q36165987Steatosis: co-factor in other liver diseases.
Q81446455The accuracy of sonography in predicting steatosis and fibrosis in chronic hepatitis C
Q45457722The extent of liver steatosis in chronic hepatitis C virus infection is mirrored by caspase activity in serum
Q90076021The role of cellular prion protein in lipid metabolism in the liver
Q82663340Vulnerability of experimentally induced fatty liver to heat stress in rats
Q80066082[Can metabolic steatohepatitis be treated?]
Q83868802[Liver apoptosis]

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