Mechanisms of lymphatic metastasis

scientific article published on 03 March 2014

Mechanisms of lymphatic metastasis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI71606
P932PMC publication ID3938272
P698PubMed publication ID24590277

P50authorMichael DetmarQ64867609
P2093author name stringSinem Karaman
P2860cites workLymphangiogenesis and cancer metastasisQ84190566
VEGF-C promotes immune tolerance in B16 melanomas and cross-presentation of tumor antigen by lymph node lymphaticsQ84621185
Dynamics of lymphatic regeneration and flow patterns after lymph node dissectionQ86647272
LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronanQ22008808
Involvement of chemokine receptors in breast cancer metastasisQ24290909
VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular developmentQ24316025
Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumorsQ24675750
Inhibition of VEGF-C modulates distal lymphatic remodeling and secondary metastasisQ27311384
Do all roads lead to Rome? Routes to metastasis developmentQ27692533
VEGF-D promotes the metastatic spread of tumor cells via the lymphaticsQ28200072
Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasisQ28200101
LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosisQ28207071
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formationQ28285842
Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesisQ28587821
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through METQ29618139
Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cellsQ30415907
Lymphatic endothelial cells - key players in regulation of tolerance and immunityQ30424567
Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentationQ30434547
Sentinel node mapping for breast cancer: current situationQ30464471
Intratumoral lymphatic vessels: a case of mistaken identity or malfunction?Q77794181
Chemokine receptor CXCR3 promotes colon cancer metastasis to lymph nodesQ79767236
Increased sentinel lymph node lymphangiogenesis is associated with nonsentinel axillary lymph node involvement in breast cancer patients with a positive sentinel nodeQ81310337
Hepatocyte growth factor is a lymphangiogenic factor with an indirect mechanism of actionQ82312177
Activation of the VEGFR-3 pathway by VEGF-C attenuates UVB-induced edema formation and skin inflammation by promoting lymphangiogenesisQ82588722
Lymphatic invasion in cutaneous melanoma is associated with sentinel lymph node metastasisQ82719711
Visualization of tumor blockage and rerouting of lymphatic drainage in penile cancer patients by use of SPECT/CTQ83366232
Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasisQ83817384
Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouseQ30499924
Mechanoinduction of lymph vessel expansionQ30505376
Near-Infrared Fluorescence Imaging in Humans with Indocyanine Green: A Review and UpdateQ30524322
Use of a PEG-conjugated bright near-infrared dye for functional imaging of rerouting of tumor lymphatic drainage after sentinel lymph node metastasisQ30539614
Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses.Q30541916
An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesisQ33455334
Breast cancer prognosis and occult lymph node metastases, isolated tumor cells, and micrometastasesQ33535173
Hepatocyte growth factor promotes lymphatic vessel formation and functionQ33919993
Tumor lymphangiogenesis predicts melanoma metastasis to sentinel lymph nodesQ33986146
B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilizationQ33993521
The lymphatic system in health and diseaseQ34015299
Blockade of vascular endothelial growth factor receptor-3 signaling inhibits fibroblast growth factor-2-induced lymphangiogenesis in mouse cornea.Q34066152
Insulin-like growth factors 1 and 2 induce lymphangiogenesis in vivoQ34098683
Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammationQ34161479
Sphingosine-1-phosphate produced by sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesis.Q34251293
PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasisQ34359534
Phenotype-based high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesisQ34403458
Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.Q34455428
Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endotheliumQ34502407
Metastatic pathways and time courses in the orderly progression of cutaneous melanomaQ34524987
An important role of lymphatic vessel activation in limiting acute inflammationQ34997755
Vascular endothelial growth factor C attenuates joint damage in chronic inflammatory arthritis by accelerating local lymphatic drainage in miceQ35146135
Insights into the mechanisms of lymph node metastasisQ35181938
VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sitesQ35616124
Tumor-induced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasisQ35750191
Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survivalQ35791518
Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasisQ35842980
Inflammation-induced lymph node lymphangiogenesis is reversibleQ35952004
In vivo imaging of inflammation- and tumor-induced lymph node lymphangiogenesis by immuno-positron emission tomographyQ36098586
Quantitative imaging of lymphatic function with liposomal indocyanine greenQ36098607
Lymphangiogenesis and cancerQ36137692
VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodesQ36384880
VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasisQ36403416
Adrenomedullin gene dosage correlates with tumor and lymph node lymphangiogenesisQ36534347
Induction of lymphangiogenesis in and around axillary lymph node metastases of patients with breast cancerQ36611984
First international consensus on the methodology of lymphangiogenesis quantification in solid human tumoursQ36612618
An important role of blood and lymphatic vessels in inflammation and allergyQ36616466
Characterization and distribution of an oncofetal antigen (M2A antigen) expressed on testicular germ cell tumoursQ36617968
Non-invasive dynamic near-infrared imaging and quantification of vascular leakage in vivo.Q37020622
Mechanisms of lymphatic metastasis in human colorectal adenocarcinomaQ37404735
Nodal lymphangiogenesis and metastasis: Role of tumor-induced lymphatic vessel activation in extramammary Paget's diseaseQ37413735
Dose-dependent response of FGF-2 for lymphangiogenesisQ37415307
Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainageQ37635188
Lymphangiogenesis: Molecular mechanisms and future promiseQ37697245
Interaction of tumor cells and lymphatic vessels in cancer progressionQ37969667
Molecular mechanisms and imaging of lymphatic metastasisQ38090228
Mechanical forces in lymphatic vascular development and diseaseQ38105904
The inflammatory response of lymphatic endotheliumQ38155100
Intratumoral lymphangiogenesis and lymph node metastasis in head and neck cancer.Q38457507
Anti-lymphangiogenesis effects of a specific anti-interleukin 7 receptor antibody in lung cancer model in vivoQ39081980
Evidence for the interaction of fibroblast growth factor-2 with the lymphatic endothelial cell marker LYVE-1.Q39221390
Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21.Q39722616
Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implicationsQ40243316
Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vesselsQ40414498
The crucial role of macrophages in lymphangiogenesisQ41945366
B lymphocyte-specific c-Myc expression stimulates early and functional expansion of the vasculature and lymphatics during lymphomagenesisQ42086633
Transmural flow modulates cell and fluid transport functions of lymphatic endotheliumQ42466882
CXCR4 signaling regulates metastasis of chemoresistant melanoma cells by a lymphatic metastatic nicheQ42833135
Vascular endothelial growth factor-C stimulates the lymphatic pump by a VEGF receptor-3-dependent mechanismQ46119200
Inflammation-induced uptake and degradation of the lymphatic endothelial hyaluronan receptor LYVE-1.Q46989487
Sentinel lymph node pressure in breast cancerQ50276883
VEGF-C and VEGF-D blockade inhibits inflammatory skin carcinogenesis.Q50972973
Expansion of the lymphatic vasculature in cancer and inflammation: new opportunities for in vivo imaging and drug delivery.Q53109783
In vivo imaging of lymph node lymphangiogenesis by immuno-positron emission tomography.Q53124507
Tissue Fluid Pressure and Flow during Pneumatic Compression in Lymphedema of Lower LimbsQ56779996
Photodynamic Ablation of Lymphatic Vessels and Intralymphatic Cancer Cells Prevents MetastasisQ57381940
Preexisting Lymphatic Endothelium but not Endothelial Progenitor Cells Are Essential for Tumor Lymphangiogenesis and Lymphatic MetastasisQ57382127
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasisQ57382204
Identification of the surface-accessible, lineage-specific vascular proteome by two-dimensional peptide mappingQ57912046
A Novel Gene Expression Profile in Lymphatics Associated with Tumor Growth and Nodal MetastasisQ58807977
Prox1 function is required for the development of the murine lymphatic systemQ73025820
Expression of CC chemokine receptor-7 and regional lymph node metastasis of B16 murine melanomaQ77137462
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)922-928
P577publication date2014-03-03
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleMechanisms of lymphatic metastasis
P478volume124

Reverse relations

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