Long-Term Treatment of Native LDL Induces Senescence of Cultured Human Endothelial Cells

scientific article published on 19 January 2017

Long-Term Treatment of Native LDL Induces Senescence of Cultured Human Endothelial Cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1155/2017/6487825
P932PMC publication ID5288541
P698PubMed publication ID28197300

P50authorSung Yeul YangQ89814383
P2093author name stringHyun Joong Yoon
Hoon Park
Sung-Tack Oh
P2860cites workVascular endothelial senescence: from mechanisms to pathophysiology.Q37335759
Circulating oxidized low-density lipoprotein: a biomarker of atherosclerosis and cardiovascular risk?Q37355913
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Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescenceQ39674577
Oxidized or acetylated low density lipoproteins are rapidly cleared by the liver in mice with disruption of the scavenger receptor class A type I/II geneQ39787179
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Different fate in vivo of oxidatively modified low density lipoprotein and acetylated low density lipoprotein in rats. Recognition by various scavenger receptors on Kupffer and endothelial liver cellsQ41942451
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Native low-density lipoprotein induces endothelial nitric oxide synthase dysfunction: role of heat shock protein 90 and caveolin-1.Q42522933
Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromesQ43578106
Circulating oxidized LDL is associated with subclinical atherosclerosis development and inflammatory cytokines (AIR Study).Q44063974
Oxidized low-density lipoprotein induces endothelial progenitor cell senescence, leading to cellular dysfunctionQ44965792
Colorimetric cell proliferation assay for microorganisms in microtiter plate using water-soluble tetrazolium saltsQ46513534
Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteinsQ59060592
Oxidized low-density lipoprotein induces apoptosis of human endothelial cells by activation of CPP32-like proteases. A mechanistic clue to the 'response to injury' hypothesis.Q64907197
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Native LDL increases endothelial cell adhesiveness by inducing intercellular adhesion molecule-1Q71066404
Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anionQ71705751
Impairment of endothelium-dependent dilation in rabbit renal arteries by oxidized lipoprotein(a). Role of oxygen-derived radicalsQ72034148
Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in womenQ72069112
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Evaluation of 2',7'-dichlorofluorescin and dihydrorhodamine 123 as fluorescent probes for intracellular H2O2 in cultured endothelial cellsQ72970166
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Oxidized LDL in carotid plaques and plasma associates with plaque instabilityQ78366337
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)Q24293520
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Native LDL and minimally oxidized LDL differentially regulate superoxide anion in vascular endothelium in situQ28215041
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Effects of native and modified low-density lipoproteins on monocyte recruitment in atherosclerosisQ30443792
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Quantitative assay of senescence-associated beta-galactosidase activity in mammalian cell extracts.Q33988482
Methods to detect biomarkers of cellular senescence: the senescence-associated beta-galactosidase assayQ34005199
Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytesQ34106524
Increased lipid peroxidation in LDL from type-2 diabetic patientsQ34152357
Aging-associated changes in vascular activity: a potential link to geriatric cardiovascular diseaseQ34422242
Putting the stress on senescenceQ34430830
Structure and physiologic function of the low-density lipoprotein receptorQ34650688
Role of telomere in endothelial dysfunction in atherosclerosisQ34916136
Modified low density lipoprotein and its constituents augment cytokine-activated vascular cell adhesion molecule-1 gene expression in human vascular endothelial cellsQ35553734
Vascular cell senescence and vascular agingQ35661173
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The natural history of coronary atherosclerosisQ35942966
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Cellular senescence in vivo: its relevance in ageing and cardiovascular disease.Q36170065
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Telomere loss: mitotic clock or genetic time bomb?Q36706939
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectendotheliumQ111140
P304page(s)6487825
P577publication date2017-01-19
P1433published inOxidative Medicine and Cellular LongevityQ26840015
P1476titleLong-Term Treatment of Native LDL Induces Senescence of Cultured Human Endothelial Cells
P478volume2017

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cites work (P2860)
Q47137702Erratum to "Long-Term Treatment of Native LDL Induces Senescence of Cultured Human Endothelial Cells".
Q64092526Low density lipoprotein mimics insulin action on autophagy and glucose uptake in endothelial cells
Q59677148Senescent Microvesicles: A Novel Advance in Molecular Mechanisms of Atherosclerotic Calcification

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