Low density lipoprotein mimics insulin action on autophagy and glucose uptake in endothelial cells

Low density lipoprotein mimics insulin action on autophagy and glucose uptake in endothelial cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-019-39559-7
P932PMC publication ID6395761
P698PubMed publication ID30816192

P2093author name stringWenjing Li
Ying Zhao
Lin Zhu
Ye Li
Xiaoyan Yang
Si Jin
Shuli Liu
Guangjie Wu
Juyi Li
Xiangli Bai
Xiong Jia
Wenzhuo Cheng
P2860cites workThe LDL receptorQ24658039
Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagyQ27675343
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signallingQ28131740
Rosuvastatin to prevent vascular events in men and women with elevated C-reactive proteinQ29547752
How to interpret LC3 immunoblottingQ29614175
Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancerQ29618030
In-Depth Proteomics Identifies a Role for Autophagy in Controlling Reactive Oxygen Species Mediated Endothelial Permeability.Q46539574
The neuroprotection of insulin on ischemic brain injury in rat hippocampus through negative regulation of JNK signaling pathway by PI3K/Akt activationQ46600045
Sphingosine-1-Phosphate Receptor 1, Expressed in Myeloid Cells, Slows Diet-Induced Atherosclerosis and Protects against Macrophage Apoptosis in Ldlr KO Mice.Q47303580
IL-37 induces autophagy in hepatocellular carcinoma cells by inhibiting the PI3K/AKT/mTOR pathwayQ51039901
Impact of Novel LDL-C Assessment on the Utility of Secondary Non-HDL-C and ApoB Targets in Selected Worldwide Dyslipidemia Guidelines.Q51245974
Inhibition of endothelial p53 improves metabolic abnormalities related to dietary obesity.Q52650465
The association between insulin and low-density lipoprotein receptorsQ53676952
Caveats to aggressive lowering of lipids by specific statinsQ54511288
Proof That Lower Is Better--LDL Cholesterol and IMPROVE-ITQ85287731
Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trialsQ29622947
Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP.Q30488194
Enhanced autophagy blocks angiogenesis via degradation of gastrin-releasing peptide in neuroblastoma cellsQ33655421
An activator of mTOR inhibits oxLDL-induced autophagy and apoptosis in vascular endothelial cells and restricts atherosclerosis in apolipoprotein E⁻/⁻ miceQ33827198
Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: a meta-analysisQ34027392
Statin use and risk of diabetes mellitus in postmenopausal women in the Women's Health Initiative.Q34245974
Beneficial cardiovascular pleiotropic effects of statinsQ34327115
Regulation of amino acid and glucose transporters in endothelial and smooth muscle cellsQ35035933
Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 miceQ35043474
Activation of the PI3K/Akt pathway and chemotherapeutic resistanceQ35046899
Mechanism and role of insulin receptor endocytosisQ35648318
PI3K/Akt signalling pathway and cancer.Q35692250
Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and traffickingQ35723690
ARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosisQ35852802
Macrophage autophagy plays a protective role in advanced atherosclerosisQ35877886
Effects of autophagy on lipopolysaccharide-induced vascular hyper-permeabilityQ36081859
Visualization of the binding, endocytosis, and transcytosis of low-density lipoprotein in the arterial endothelium in situQ36207373
Statin therapy and risk of developing type 2 diabetes: a meta-analysisQ37364976
Long-Term Treatment of Native LDL Induces Senescence of Cultured Human Endothelial CellsQ37620261
Differing effect of statins on insulin sensitivity in non-diabetics: a systematic review and meta-analysisQ37632786
Reactive oxygen species mediate angiotensin II-induced transcytosis of low-density lipoprotein across endothelial cells.Q37713975
An Overview of Autophagy: Morphology, Mechanism, and RegulationQ38110938
Autophagy deficiency in beta cells leads to compromised unfolded protein response and progression from obesity to diabetes in miceQ38330390
mTOR: a pharmacologic target for autophagy regulationQ38345168
Statin use and the risk of developing diabetes: a network meta-analysisQ38859404
Effects of MβCD on Lipoxygenase-Induced LDL OxidationQ38982977
Wogonoside induces autophagy in MDA-MB-231 cells by regulating MAPK-mTOR pathwayQ39273763
Beclin1/PI3K-Mediated Autophagy Prevents Hypoxia-Induced Apoptosis in EAhy926 Cell LineQ39516667
Inflammatory stress increases unmodified LDL uptake via LDL receptor: an alternative pathway for macrophage foam-cell formationQ39837080
Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling.Q40158710
2-NBDG as a fluorescent indicator for direct glucose uptake measurementQ40369331
Effect of pitavastatin on glucose, HbA1c and incident diabetes: A meta-analysis of randomized controlled clinical trials in individuals without diabetesQ40835767
Effects of intensive pitavastatin therapy on glucose control in patients with non-ST elevation acute coronary syndromeQ41265772
Autophagy links inflammasomes to atherosclerotic progression.Q41825615
Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat dietQ42442818
The autophagy-lysosome pathway: a novel mechanism involved in the processing of oxidized LDL in human vascular endothelial cellsQ43133168
Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.Q44605205
Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy.Q44653812
Meta-analysis of impact of different types and doses of statins on new-onset diabetes mellitusQ44850160
Nitric oxide stimulates 18F-FDG uptake in human endothelial cells through increased hexokinase activity and GLUT1 expression.Q45254042
Endothelial Permeability, Ldl Deposition, and Cardiovascular Risk Factors - A Review.Q46059179
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectautophagyQ288322
preproinsulinQ7240673
P304page(s)3020
P577publication date2019-02-28
P1433published inScientific ReportsQ2261792
P1476titleLow density lipoprotein mimics insulin action on autophagy and glucose uptake in endothelial cells
P478volume9

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