Autophagy links inflammasomes to atherosclerotic progression.

scientific article published on 20 March 2012

Autophagy links inflammasomes to atherosclerotic progression. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CMET.2012.02.011
P932PMC publication ID3322320
P698PubMed publication ID22440612
P5875ResearchGate publication ID221969447

P50authorClay F. SemenkovichQ42738655
Jenny TingQ50858300
Seungmin HwangQ55293404
Babak RazaniQ56835760
Haitao WenQ89457548
Trey ColemanQ114301141
Herbert W. VirginQ28407524
P2093author name stringMichael B Kastan
Chu Feng
Roy Emanuel
P2860cites workGuidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotesQ23757358
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient miceQ24303752
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressorQ24569647
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Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy geneQ24617547
Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in miceQ24623151
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilizationQ24631966
Oxidation of free amino acids and amino acid residues in proteins by radiolysis and by metal-catalyzed reactionsQ40835305
Cholesterol and oxysterol metabolism and subcellular distribution in macrophage foam cells. Accumulation of oxidized esters in lysosomesQ40899444
Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptorQ41424778
Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalitiesQ43678714
Dietary restriction reduces atherosclerosis and oxidative stress in the aorta of apolipoprotein E-deficient miceQ44014870
Rapamycin attenuates atherosclerosis induced by dietary cholesterol in apolipoprotein-deficient mice through a p27 Kip1 -independent pathwayQ44716927
7-ketocholesterol induces protein ubiquitination, myelin figure formation, and light chain 3 processing in vascular smooth muscle cellsQ45086352
Aggregated LDL and lipid dispersions induce lysosomal cholesteryl ester accumulation in macrophage foam cellsQ46604874
"New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasisQ46626411
Rapamycin attenuates atherosclerotic plaque progression in apolipoprotein E knockout mice: inhibitory effect on monocyte chemotaxisQ46701396
Prevention of atherosclerosis by the mTOR inhibitor everolimus in LDLR-/- mice despite severe hypercholesterolemiaQ46916538
Effects of heterozygous lipoprotein lipase deficiency on diet-induced atherosclerosis in miceQ47920076
Critical role of apoptotic speck protein containing a caspase recruitment domain (ASC) and NLRP3 in causing necrosis and ASC speck formation induced by Porphyromonas gingivalis in human cellsQ51833225
How shall I eat thee?Q51983235
Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in miceQ54034693
Cholesterol delivered to macrophages by oxidized low density lipoprotein is sequestered in lysosomes and fails to efflux normallyQ54034996
The intracellular storage and turnover of apolipoprotein B of oxidized LDL in macrophagesQ54268090
Oxidized low density lipoprotein is resistant to cathepsins and accumulates within macrophagesQ54290578
The Inflammasome in Atherosclerosis and Type 2 DiabetesQ62818661
Cholesterol crystal formation and growth in model bile solutionsQ71073142
Cell composition, replication, and apoptosis in atherosclerotic plaques after 6 months of cholesterol withdrawalQ77167596
Autophagy suppresses tumorigenesis through elimination of p62Q24650670
Autophagy in the Pathogenesis of DiseaseQ27860558
Suppression of basal autophagy in neural cells causes neurodegenerative disease in miceQ28131756
A role for mitochondria in NLRP3 inflammasome activationQ28131794
Loss of autophagy in the central nervous system causes neurodegeneration in miceQ28131804
Differential activation of the inflammasome by caspase-1 adaptors ASC and IpafQ28266417
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stressQ28506886
Autophagy in the heart and liver during normal aging and calorie restrictionQ28582989
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient miceQ28588080
Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1βQ29030555
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell deathQ29547297
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasomeQ29547419
The role of autophagy during the early neonatal starvation periodQ29547489
Autophagy as a regulated pathway of cellular degradationQ29547914
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta productionQ29614472
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1Q29614473
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystalsQ29615704
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signalingQ29616024
The Inflammasome NLRs in Immunity, Inflammation, and Associated DiseasesQ29616025
Self-eating and self-killing: crosstalk between autophagy and apoptosisQ29617748
Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammationQ33644572
Macrophage fatty-acid synthase deficiency decreases diet-induced atherosclerosisQ34004031
Autophagy: basic principles and relevance to diseaseQ34585381
Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for DegradationQ34684708
Small nucleolar RNAs U32a, U33, and U35a are critical mediators of metabolic stressQ35111712
Fatty acid synthase modulates homeostatic responses to myocardial stress.Q35183031
Cardiac autophagy is a maladaptive response to hemodynamic stressQ35839989
Sequestration of acetylated LDL and cholesterol crystals by human monocyte-derived macrophagesQ36235266
Advanced atherosclerotic foam cell formation has features of an acquired lysosomal storage disorderQ36481021
Autophagy in atherosclerosis: a cell survival and death phenomenon with therapeutic potentialQ37391884
The NLRP3 inflammasome: a sensor for metabolic danger?Q37675505
Mitochondrial reactive oxygen species drive proinflammatory cytokine productionQ37847792
The inflammasome: an integrated viewQ37925072
Computed tomographic assessment of atherosclerosis in ancient Egyptian mummiesQ38869586
Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipaseQ40374390
Lysosomal cholesterol derived from mildly oxidized low density lipoprotein is resistant to effluxQ40820350
P4510describes a project that usesImageJQ1659584
P433issue4
P921main subjectatherosclerosisQ12252367
autophagyQ288322
inflammasome complexQ412405
P304page(s)534-544
P577publication date2012-03-20
P1433published inCell MetabolismQ1254684
P1476titleAutophagy links inflammasomes to atherosclerotic progression
P478volume15

Reverse relations

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