Fatty acid synthase modulates homeostatic responses to myocardial stress.

scientific article

Fatty acid synthase modulates homeostatic responses to myocardial stress. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111.230508
P932PMC publication ID3162454
P698PubMed publication ID21757749

P50authorClay F. SemenkovichQ42738655
Babak RazaniQ56835760
Irfan J LodhiQ57370057
Trey ColemanQ114301141
P2093author name stringJeffrey E Saffitz
Daniel P Kelly
Gerald W Dorn
Colin G Nichols
Haixia Zhang
P Christian Schulze
Attila Kovacs
Joel D Schilling
Veli K Topkara
Chu Feng
John Verbsky
P2860cites workCa2+/calmodulin-dependent protein kinase II is a modulator of CARMA1-mediated NF-kappaB activationQ24295025
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Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in uteroQ35142911
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Fatty acid homeostasis in the normoxic and ischemic heartQ35531455
Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of beta-catenin in prostate cancerQ35572195
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Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis.Q35921527
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Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice.Q37170829
Polyunsaturated fatty acid modulation of voltage-gated ion channelsQ37284810
SREBPs: physiology and pathophysiology of the SREBP familyQ37368394
Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.Q37369799
Rodent models of diabetic cardiomyopathy.Q37591072
Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophyQ37596176
Secondary consequences of beta cell inexcitability: identification and prevention in a murine model of K(ATP)-induced neonatal diabetes mellitusQ39035715
Myocardial metabolism of fatty acidsQ40331547
Calcium/calmodulin-dependent protein kinase II (CaMKII) localization acts in concert with substrate targeting to create spatial restriction for phosphorylationQ40483909
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Regulation of fatty acid synthase (FAS).Q41646396
Inhibiting long chain fatty Acyl CoA synthetase increases basal and agonist-stimulated NO synthesis in endotheliumQ42464471
RETRACTED: L-type Ca2+ channel facilitation mediated by phosphorylation of the beta subunit by CaMKII.Q42597255
Palmitate attenuates myocardial contractility through augmentation of repolarizing Kv currentsQ42927715
CaMKII and a failing strategy for growth in heartQ43140407
Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalitiesQ43678714
A role for peroxisome proliferator-activated receptor alpha (PPARalpha ) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated wiQ43816422
Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophyQ44123766
Remodeling of excitation-contraction coupling in transgenic mice expressing ATP-insensitive sarcolemmal KATP channelsQ44680736
LV systolic performance improves with development of hypertrophy after transverse aortic constriction in miceQ46383286
"New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasisQ46626411
Transgenic overexpression of SUR1 in the heart suppresses sarcolemmal K(ATP).Q46649606
Heterogeneous expression of repolarizing, voltage-gated K+ currents in adult mouse ventriclesQ47350584
Alterations of gene expression in failing myocardium following left ventricular assist device supportQ47806965
Involvement of fatty acid synthase in axonal development in mouse embryos.Q47822527
Identification of a gene expression profile that differentiates between ischemic and nonischemic cardiomyopathy.Q51578105
Klf2 is an essential regulator of vascular hemodynamic forces in vivo.Q52000298
Protection conferred by myocardial ATP-sensitive K+ channels in pressure overload-induced congestive heart failure revealed in KCNJ11 Kir6.2-null mutant.Q53593992
Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice.Q54034693
Mechanisms for association of Ca2+/calmodulin-dependent protein kinase II with lipid raftsQ57359506
Inhibition of endothelial cell proliferation and angiogenesis by orlistat, a fatty acid synthase inhibitorQ57373885
Calmodulin kinase II inhibition protects against structural heart diseaseQ59975125
Regulation of Fatty Acid Utilization in Isolated Perfused Rat HeartsQ69637537
Effect of arachidonic acid on the L-type calcium current in frog cardiac myocytesQ71335668
In Vivo Echocardiographic Detection of Enhanced Left Ventricular Function in Gene-Targeted Mice With Phospholamban DeficiencyQ71974396
Myosin heavy chain regulation and myocyte contractile depression after LV hypertrophy in aortic-banded miceQ72101575
Diabetic cardiomyopathyQ72189534
Defective sarcoplasmic reticular calcium transport in diabetic cardiomyopathyQ72554854
Glucose and fatty acid metabolism in the isolated working mouse heartQ73071219
Decompensation of pressure-overload hypertrophy in G alpha q-overexpressing miceQ74519768
IMPORTANCE OF FATTY ACID IN MYOCARDIAL METABOLISMQ77127304
CaM kinase augments cardiac L-type Ca2+ current: a cellular mechanism for long Q-T arrhythmiasQ77855621
Yin and Yang of myocardial transforming growth factor-beta1: timing is everythingQ81752705
P433issue35
P407language of work or nameEnglishQ1860
P921main subjectfatty acidQ61476
P1104number of pages13
P304page(s)30949-30961
P577publication date2011-07-08
P1433published inJournal of Biological ChemistryQ867727
P1476titleFatty acid synthase modulates homeostatic responses to myocardial stress
P478volume286

Reverse relations

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