Minireview: the melanocortin 2 receptor accessory proteins.

scientific article published on 23 October 2009

Minireview: the melanocortin 2 receptor accessory proteins. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1210/ME.2009-0283
P932PMC publication ID5419097
P698PubMed publication ID19855089

P50authorTom R WebbQ84198625
Adrian J. L. ClarkQ124365891
P2860cites workMRAP and MRAP2 are bidirectional regulators of the melanocortin receptor familyQ24310708
RTP family members induce functional expression of mammalian odorant receptorsQ24315887
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptorQ24323946
The cloning of a family of genes that encode the melanocortin receptorsQ24337156
Members of RTP and REEP gene families influence functional bitter taste receptor expressionQ24337758
Hereditary isolated glucocorticoid deficiency is associated with abnormalities of the adrenocorticotropin receptor geneQ24594715
Regions of melanocortin 2 (MC2) receptor accessory protein necessary for dual topology and MC2 receptor trafficking and signalingQ24655993
Genome-wide atlas of gene expression in the adult mouse brainQ26253934
Multiple amylin receptors arise from receptor activity-modifying protein interaction with the calcitonin receptor gene productQ28138337
Annotation of human chromosome 21 for relevance to Down syndrome: gene structure and expression analysisQ28201300
Novel receptor partners and function of receptor activity-modifying proteinsQ28215813
Familial glucocorticoid deficiency associated with point mutation in the adrenocorticotropin receptorQ28248720
Opposite effects of the melanocortin-2 (MC2) receptor accessory protein MRAP on MC2 and MC5 receptor dimerization and traffickingQ28248884
Cloning and functional characterization of a family of receptors for the melanotropic peptidesQ28263520
GPCR modulation by RAMPsQ28268136
Inherited ACTH insensitivity illuminates the mechanisms of ACTH actionQ28280435
Differential regulation of the human adrenocorticotropin receptor [melanocortin-2 receptor (MC2R)] by human MC2R accessory protein isoforms alpha and beta in isogenic human embryonic kidney 293 cellsQ28299255
Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2Q28302878
Effects of recombinant agouti-signaling protein on melanocortin actionQ28305219
Melanocortin-2 receptor accessory protein MRAP forms antiparallel homodimersQ36299865
Visualization of molecular interactions by fluorescence complementationQ36453786
Studies on the physiological functions of the melanocortin systemQ36640631
Structure and function of the melanocortin2 receptor accessory protein (MRAP).Q37181193
The melanocortin 2 receptor accessory protein exists as a homodimer and is essential for the function of the melanocortin 2 receptor in the mouse y1 cell line.Q40030172
The melanocortin system in Fugu: determination of POMC/AGRP/MCR gene repertoire and synteny, as well as pharmacology and anatomical distribution of the MCRsQ40604442
Functional characterization of naturally occurring mutations of the human adrenocorticotropin receptor: poor correlation of phenotype and genotypeQ40936201
Adrenocorticotropin-resistant mutants of the Y1 adrenal cell line fail to express the adrenocorticotropin receptorQ41352345
Identification of novel putative membrane proteins selectively expressed during adipose conversion of 3T3-L1 cellsQ42814144
Distinct melanocortin 2 receptor accessory protein domains are required for melanocortin 2 receptor interaction and promotion of receptor trafficking.Q45959968
Divergence of melanocortin pathways in the control of food intake and energy expenditureQ48707234
Failed export of the adrenocorticotrophin receptor from the endoplasmic reticulum in non-adrenal cells: evidence in support of a requirement for a specific adrenal accessory factorQ63984815
Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body massQ74268345
Adrenocorticotropin insensitivity syndromesQ77712276
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)475-484
P577publication date2009-10-23
P1433published inMolecular EndocrinologyQ3319475
P1476titleMinireview: the melanocortin 2 receptor accessory proteins
P478volume24

Reverse relations

cites work (P2860)
Q2677053760 YEARS OF POMC: Melanocortin receptors: evolution of ligand selectivity for melanocortin peptides
Q26740152ACTH Antagonists
Q38715577ACTH Receptor (MC2R) Specificity: What Do We Know About Underlying Molecular Mechanisms?
Q36807768ACTH promotes chondrogenic nodule formation and induces transient elevations in intracellular calcium in rat bone marrow cell cultures via MC2-R signaling
Q38846601Adolescence and the ontogeny of the hormonal stress response in male and female rats and mice
Q45064023Adrenocorticotropic hormone and 1,25-dihydroxyvitamin D3 enhance human osteogenesis in vitro by synergistically accelerating the expression of bone-specific genes
Q45843882Analysis of the pharmacological properties of chicken melanocortin-2 receptor (cMC2R) and chicken melanocortin-2 accessory protein 1 (cMRAP1).
Q38203079Analyzing the activation of the melanocortin-2 receptor of tetrapods
Q47828534Analyzing the effects of co-expression of chick (Gallus gallus) melanocortin receptors with either chick MRAP1 or MRAP2 in CHO cells on sensitivity to ACTH(1-24) or ACTH(1-13)NH2: Implications for the avian HPA axis and avian melanocortin circuits i
Q46468395Association of estradiol on expression of melanocortin receptors and their accessory proteins in the liver of chicken (Gallus gallus).
Q46572745Characterization of melanocortin receptors from stingray Dasyatis akajei, a cartilaginous fish.
Q51605173Decreased melanocortin-4 receptor function conferred by an infrequent variant at the human melanocortin receptor accessory protein 2 gene.
Q52615555Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.
Q42583795Development of melanoma-targeted polymer micelles by conjugation of a melanocortin 1 receptor (MC1R) specific ligand
Q34570374Early vertebrate origin of melanocortin 2 receptor accessory proteins (MRAPs).
Q42508386Effects of food restriction on steroidogenesis in dispersed adrenocortical cells from Yarrow's Spiny Lizard (Sceloporus jarrovii).
Q93369255Elephant shark melanocortin receptors: Novel interactions with MRAP1 and implication for the HPI axis
Q44525882Estrogen Suppresses Interaction of Melanocortin 2 Receptor and Its Accessory Protein in the Primate Fetal Adrenal Cortex
Q51730492Evaluating the interactions between red stingray (Dasyatis akajei) melanocortin receptors and elephant shark (Callorhinchus milii) MRAP1 and MRAP2 following stimulation with either stingray ACTH(1-24) or stingray Des-Acetyl-αMSH: A pharmacological s
Q38042267Evolution of melanocortin receptors in cartilaginous fish: melanocortin receptors and the stress axis in elasmobranches
Q38103638Evolution of the melanocortin-2 receptor in tetrapods: studies on Xenopus tropicalis MC2R and Anolis carolinensis MC2R.
Q38133424Family of melanocortin receptor (MCR) genes in mammals-mutations, polymorphisms and phenotypic effects
Q51765921Functional expression of frog and rainbow trout melanocortin 2 receptors using heterologous MRAP1s.
Q39672404Gene therapy for advanced melanoma: selective targeting and therapeutic nucleic acids.
Q38694281Hypothesis and Theory: Revisiting Views on the Co-evolution of the Melanocortin Receptors and the Accessory Proteins, MRAP1 and MRAP2
Q36439446Identification of an MRAP-independent melanocortin-2 receptor: functional expression of the cartilaginous fish, Callorhinchus milii, melanocortin-2 receptor in CHO cells
Q92905449Identifying Common Features in the Activation of Melanocortin-2 Receptors: Studies on the Xenopus tropicalis Melanocortin-2 Receptor
Q40122759Identifying the activation motif in the N-terminal of rainbow trout and zebrafish melanocortin-2 receptor accessory protein 1 (MRAP1) orthologs
Q38287475Intracellular signaling mechanisms of the melanocortin receptors: current state of the art.
Q52686348MC4R Agonists: Structural Overview on Antiobesity Therapeutics.
Q39473235Mechanisms of melanocortin-2 receptor (MC2R) internalization and recycling in human embryonic kidney (hek) cells: identification of Key Ser/Thr (S/T) amino acids
Q27013622Melanocortin receptor accessory proteins in adrenal disease and obesity
Q82672228Melanocortin receptor subtypes in interrenal cells and corticotropic activity of α-melanocyte-stimulating hormones in barfin flounder, Verasper moseri
Q44974718Neonatal hyperpigmentation: diagnosis of familial glucocorticoid deficiency with a novel mutation in the melanocortin-2 receptor gene
Q38099827Observations on the evolution of the melanocortin receptor gene family: distinctive features of the melanocortin-2 receptor
Q37866429Observations on the ligand selectivity of the melanocortin 2 receptor
Q88499152Pharmacological effect of human melanocortin-2 receptor accessory protein 2 variants on hypothalamic melanocortin receptors
Q90658244Pharmacological properties of whale shark (Rhincodon typus) melanocortin-2 receptor and melancortin-5 receptor: Interaction with MRAP1 and MRAP2
Q37648372Pubertal shifts in adrenal responsiveness to stress and adrenocorticotropic hormone in male rats
Q92556852Stability and Turnover of the ACTH Receptor Complex
Q38221447Steroidogenesis-adrenal cell signal transduction
Q28260658The C-terminal domains of melanocortin-2 receptor (MC2R) accessory proteins (MRAP1) influence their localization and ACTH-induced cAMP production
Q24613957The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
Q34525556The hunt for a selective 17,20 lyase inhibitor; learning lessons from nature.
Q88042445The melanocortin-2 receptor of the rainbow trout: Identifying a role for critical positions in transmembrane domain 4, extracellular loop 2, and transmembrane domain 5 in the activation of rainbow trout MC2R
Q34088801The year in G protein-coupled receptor research
Q41873197Use of chimeric melanocortin-2 and -4 receptors to identify regions responsible for ligand specificity and dependence on melanocortin 2 receptor accessory protein.
Q38064191Using the human melanocortin-2 receptor as a model for analyzing hormone/receptor interactions between a mammalian MC2 receptor and ACTH(1-24).
Q28483679VENNTURE--a novel Venn diagram investigational tool for multiple pharmacological dataset analysis

Search more.