The melanocortin system in Fugu: determination of POMC/AGRP/MCR gene repertoire and synteny, as well as pharmacology and anatomical distribution of the MCRs

scientific article published on 23 December 2003

The melanocortin system in Fugu: determination of POMC/AGRP/MCR gene repertoire and synteny, as well as pharmacology and anatomical distribution of the MCRs is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/MOLBEV/MSH050
P698PubMed publication ID14694081
P5875ResearchGate publication ID8943649

P50authorNicole Gallo-PayetQ47451650
Helgi B. SchiöthQ30112644
P2093author name stringRobert Fredriksson
Janis Klovins
Tatjana Haitina
Davids Fridmanis
Ivo Kapa
Zuzana Kilianova
P2860cites workWhole-Genome Shotgun Assembly and Analysis of the Genome of Fugu rubripesQ22065831
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choiceQ24286950
MEGA2: molecular evolutionary genetics analysis softwareQ27860788
Low frequency of melanocortin-4 receptor (MC4R) mutations in a Mediterranean population with early-onset obesityQ28200908
The melanocortin systemQ28205910
Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptorQ28239346
A highly sensitive adenylate cyclase assayQ47871494
A "short" feedback loop in the control of ACTH secretion.Q51249697
Molecular evolution: recent cases of spliceosomal intron gain?Q52565171
An intron-less βγ-crystallin-type gene from the sponge Geodia cydoniumQ57976822
Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptidesQ28257807
A frameshift mutation in human MC4R is associated with a dominant form of obesityQ28285286
Molecular interaction of Agouti protein and Agouti-related protein with human melanocortin receptorsQ28294398
Targeted disruption of the melanocortin-4 receptor results in obesity in miceQ28302831
The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprintsQ29547321
Proto-splice site model of intron origin.Q30376952
Comparative analysis of the polycystic kidney disease 1 (PKD1) gene reveals an integral membrane glycoprotein with multiple evolutionary conserved domainsQ30428328
Widespread expression of Agouti-related protein (AGRP) in the chicken: a possible involvement of AGRP in regulating peripheral melanocortin systems in the chickenQ30859400
Cloning and characterization of the guinea pig neuropeptide Y receptor Y5.Q30985216
Pharmacological comparison of rat and human melanocortin 3 and 4 receptors in vitroQ31068244
One melanocortin 4 and two melanocortin 5 receptors from zebrafish show remarkable conservation in structure and pharmacologyQ31090756
Remarkable synteny conservation of melanocortin receptors in chicken, human, and other vertebratesQ31139639
The structure and evolution of the melanocortin and MCH receptors in fish and mammalsQ33964758
The physiological role of melanocortin receptorsQ34254198
Evolutionary significance of proopiomelanocortin in agnatha and chondrichthyesQ34278116
Evolution of the vertebrate genome as reflected in paralogous chromosomal regions in man and the house mouseQ34364325
Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiencyQ35126471
Late changes in spliceosomal introns define clades in vertebrate evolutionQ35619508
De novo insertion of an intron into the mammalian sex determining gene, SRY.Q35879305
Intron "sliding" and the diversity of intron positionsQ36594300
Melanotropin and Corticotropin Are Encoded on Two Distinct Genes in the Lamprey, the Earliest Evolved Extant VertebrateQ36690902
Two types of cDNAs encoding proopiomelanocortin of sockeye salmon, Oncorhynchus nerkaQ36841066
Tetraodon fluviatilis, a new puffer fish model for genome studiesQ36859726
Deletions of the N-terminal regions of the human melanocortin receptorsQ36873167
Deciphering posttranslational processing events in the pituitary of a neopterygian fish: cloning of a gar proopiomelanocortin cDNA.Q36878479
Cloning of a neoteleost (Oreochromis mossambicus) pro-opiomelanocortin (POMC) cDNA reveals a deletion of the gamma-melanotropin region and most of the joining peptide region: implications for POMC processingQ38314930
Functional expression of the human ACTH receptor geneQ40825608
Common requirements for melanocortin-4 receptor selectivity of structurally unrelated melanocortin agonist and endogenous antagonist, Agouti proteinQ40850484
Why do genes have introns?Q40918538
The melanocortin 1, 3, 4 or 5 receptors do not have a binding epitope for ACTH beyond the sequence of alpha-MSH.Q41077921
Localization of ACTH receptor mRNA by in situ hybridization in mouse adrenal glandQ41165786
Major pharmacological distinction of the ACTH receptor from other melanocortin receptorsQ41250598
Gen(om)e duplications in the evolution of early vertebratesQ41312106
Adrenocorticotropin-resistant mutants of the Y1 adrenal cell line fail to express the adrenocorticotropin receptorQ41352345
Sturgeon proopiomelanocortin has a remnant of gamma-melanotropinQ42649039
Melanocortin receptor genes in the chicken--tissue distributionsQ42684727
Presence of melanocortin (MC4) receptor in spiny dogfish suggests an ancient vertebrate origin of central melanocortin systemQ42695423
Molecular cloning, pharmacological characterization, and brain mapping of the melanocortin 4 receptor in the goldfish: involvement in the control of food intakeQ44440502
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectpharmacologyQ128406
P304page(s)563-579
P577publication date2003-12-23
P1433published inMolecular Biology and EvolutionQ1992656
P1476titleThe melanocortin system in Fugu: determination of POMC/AGRP/MCR gene repertoire and synteny, as well as pharmacology and anatomical distribution of the MCRs
P478volume21

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