Helgi B. Schiöth

researcher

Born 2000-01-01

Helgi B. Schiöth is …
instance of (P31):
humanQ5

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P1960Google Scholar author IDPP2JpAIAAAAJ

P106occupationresearcherQ1650915
P21sex or gendermaleQ6581097

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author (P50)
Q37176691A Genetic Risk Score Is Associated with Weight Loss Following Roux-en Y Gastric Bypass Surgery
Q38724039A MIR4646 associated methylation locus is hypomethylated in adolescent depression
Q33885473A genetic risk score is differentially associated with migraine with and without aura
Q51272834A genetic risk score is significantly associated with statin therapy response in the elderly population.
Q37051506A genetic variant in proximity to the gene LYPLAL1 is associated with lower hunger feelings and increased weight loss following Roux-en-Y gastric bypass surgery
Q42115748A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers
Q41271398A methylome-wide mQTL analysis reveals associations of methylation sites with GAD1 and HDAC3 SNPs and a general psychiatric risk score
Q50625050A new, simple and robust radioligand binding method used to determine kinetic off-rate constants for unlabeled ligands. Application at α2A- and α2C-adrenoceptors.
Q36158344A resting-state fMRI study of obese females between pre- and postprandial states before and after bariatric surgery
Q48924407A significant participation of orexin-A, a potent orexigenic peptide, in the preovulatory luteinizing hormone and prolactin surges in the rat.
Q47938366A single night of partial sleep loss impairs fasting insulin sensitivity but does not affect cephalic phase insulin release in young men.
Q47638995A single night of sleep loss impairs objective but not subjective working memory performance in a sex-dependent manner
Q28077025A systematic review of resting-state functional-MRI studies in anorexia nervosa: Evidence for functional connectivity impairment in cognitive control and visuospatial and body-signal integration
Q36052383A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease
Q73544868ACTH- and alpha-MSH-induced grooming, stretching, yawning and penile erection in male rats: site of action in the brain and role of melanocortin receptors
Q40559575Activation of central melanocortin-4 receptor suppresses lipopolysaccharide-induced fever in rats
Q48124765Activation of melanocortin 4 receptors reduces the inflammatory response and prevents apoptosis induced by lipopolysaccharide and interferon-gamma in astrocytes
Q47955897Acute Sleep Loss Induces Tissue-Specific Epigenetic and Transcriptional Alterations to Circadian Clock Genes in Men.
Q48554397Acute ghrelin administration reverses depressive-like behavior induced by bilateral olfactory bulbectomy in mice
Q34248303Acute sleep deprivation enhances the brain's response to hedonic food stimuli: an fMRI study
Q35176554Acute sleep deprivation in healthy young men: impact on population diversity and function of circulating neutrophils
Q47863797Acute sleep deprivation increases food purchasing in men.
Q34328897Acute sleep deprivation increases portion size and affects food choice in young men.
Q39262156Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men.
Q58722721Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans
Q33211279Addition of a signal peptide sequence to the alpha1D-adrenoceptor gene increases the density of receptors, as determined by [3H]-prazosin binding in the membranes
Q34420848Adhesion GPCRs are widely expressed throughout the subsections of the gastrointestinal tract
Q34539256Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet
Q47878913Adolescents newly diagnosed with eating disorders have structural differences in brain regions linked with eating disorder symptoms
Q35329430Advances in kinase targeting: current clinical use and clinical trials
Q30661321Agouti-related peptide prevents steroid-induced luteinizing hormone and prolactin surges in female rats
Q44952232Alpha-melanocyte-stimulating hormone through melanocortin-4 receptor inhibits nitric oxide synthase and cyclooxygenase expression in the hypothalamus of male rats
Q55476996Altered cerebellar-insular-parietal-cingular subnetwork in adolescents in the earliest stages of anorexia nervosa: a network-based statistic analysis.
Q71865774Alternative translation initiation codon for the human melanocortin MC3 receptor does not affect the ligand binding
Q28272411An obesity-associated risk allele within the FTO gene affects human brain activity for areas important for emotion, impulse control and reward in response to food images
Q24657212Analysis of the network of feeding neuroregulators using the Allen Brain Atlas
Q34660623Anorexia nervosa is linked to reduced brain structure in reward and somatosensory regions: a meta-analysis of VBM studies
Q30843489Anorexigenic cocaine- and amphetamine-regulated transcript peptide intensifies fear reactions in rats.
Q47984662Anxiety Disorders are Associated with Low Socioeconomic Status in Women but Not in Men.
Q35894928Are You Sure? Confidence about the Satiating Capacity of a Food Affects Subsequent Food Intake
Q33481961Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI.
Q48509900Association between physical activity and brain health in older adults
Q39558585Association between shift work history and performance on the trail making test in middle-aged and elderly humans: the EpiHealth study
Q34032953Association of TMEM18 variants with BMI and waist circumference in children and correlation of mRNA expression in the PFC with body weight in rats
Q40661883Association of feather colour with constitutively active melanocortin 1 receptors in chicken
Q35567099Association of the LINGO2-related SNP rs10968576 with body mass in a cohort of elderly Swedes
Q55023633Associations Between the Prevalence of Metabolic Syndrome and Sleep Parameters Vary by Age.
Q43517109Associations of self-reported sleep disturbance and duration with academic failure in community-dwelling Swedish adolescents: sleep and academic performance at school
Q47351224Atypical anorexia nervosa is not related to brain structural changes in newly diagnosed adolescent patients
Q31976255Autoradiographic discrimination of melanocortin receptors indicates that the MC3 subtype dominates in the medial rat brain
Q35173411Avian melanocortin system: alpha-MSH may act as an autocrine/paracrine hormone: a minireview
Q34625972B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain
Q26748627BDNF DNA methylation changes as a biomarker of psychiatric disorders: literature review and open access database analysis
Q37509607BDNF polymorphisms are linked to poorer working memory performance, reduced cerebellar and hippocampal volumes and differences in prefrontal cortex in a Swedish elderly population
Q36847642Binding of cyclic and linear MSH core peptides to the melanocortin receptor subtypes
Q39892959Bis-(2-ethylhexyl) Phthalate Increases Insulin Expression and Lipid Levels in Drosophila melanogaster
Q36237225Brain insulin signaling and Alzheimer's disease: current evidence and future directions
Q35138416CDKAL1-related single nucleotide polymorphisms are associated with insulin resistance in a cross-sectional cohort of Greek children
Q26753192Candidate mechanisms underlying the association between sleep-wake disruptions and Alzheimer's disease
Q50760788Central ghrelin increases anxiety in the Open Field test and impairs retention memory in a passive avoidance task in neonatal chicks.
Q37175440Central nociceptin/orphanin FQ system elevates food consumption by both increasing energy intake and reducing aversive responsiveness
Q36852318Characterisation of D117A and H260A mutations in the melanocortin 1 receptor
Q72296957Characterisation of melanocortin receptor subtypes by radioligand binding analysis
Q71712692Characterisation of the melanocortin 4 receptor by radioligand binding
Q32064929Characterization of the binding of MSH-B, HB-228, GHRP-6 and 153N-6 to the human melanocortin receptor subtypes
Q34721980Characterization of the transporterB0AT3 (Slc6a17) in the rodent central nervous system
Q34557589Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake
Q52869822Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes.
Q47866674Chimeric melanocortin MC1 and MC3 receptors: identification of domains participating in binding of melanocyte-stimulating hormone peptides
Q74116447Chronic melanocortin 4 receptor blockage causes obesity without influencing sexual behavior in male rats
Q35220498Chronic sugar intake dampens feeding-related activity of neurons synthesizing a satiety mediator, oxytocin
Q38796691Classification, Nomenclature, and Structural Aspects of Adhesion GPCRs
Q31122697Cloning of two melanocortin (MC) receptors in spiny dogfish: MC3 receptor in cartilaginous fish shows high affinity to ACTH-derived peptides while it has lower preference to gamma-MSH.
Q31047954Cloning, tissue distribution, pharmacology and three-dimensional modelling of melanocortin receptors 4 and 5 in rainbow trout suggest close evolutionary relationship of these subtypes
Q52767211Collagen metabolism is a novel target of the neuropeptide alpha-melanocyte-stimulating hormone.
Q33211191Comparison of the current RefSeq, Ensembl and EST databases for counting genes and gene discovery
Q28573098Complexity of neural mechanisms underlying overconsumption of sugar in scheduled feeding: involvement of opioids, orexin, oxytocin and NPY
Q33969137Comprehensive analysis of localization of 78 solute carrier genes throughout the subsections of the rat gastrointestinal tract
Q33253685Comprehensive comparisons of the current human, mouse, and rat RefSeq, Ensembl, EST, and FANTOM3 datasets: identification of new human genes with specific tissue expression profile
Q34534533Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse
Q42360721Correction: Limbic-thalamo-cortical projections and reward-related circuitry integrity affects eating behavior: A longitudinal DTI study in adolescents with restrictive eating disorders
Q42342336Correction: Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus
Q30757750Corticotropin-releasing factor (CRF) induced anorexia is not influenced by a melanocortin 4 receptor blockage
Q56987479Critical evaluation of the FANTOM3 non-coding RNA transcripts
Q48347402Decreased memory for novel object recognition in chronically food-restricted mice is reversed by acute ghrelin administration
Q35104663Defining the gene repertoire and spatiotemporal expression profiles of adhesion G protein-coupled receptors in zebrafish
Q36873167Deletions of the N-terminal regions of the human melanocortin receptors
Q33920976Detailed analysis of variants in FTO in association with body composition in a cohort of 70-year-olds suggests a weakened effect among elderly
Q26999807Determinants of shortened, disrupted, and mistimed sleep and associated metabolic health consequences in healthy humans
Q34244371Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children
Q28275062Dibutyl Phthalate Exposure Disrupts Evolutionarily Conserved Insulin and Glucagon-Like Signaling in Drosophila Males
Q35477702Dietary fat quality impacts genome-wide DNA methylation patterns in a cross-sectional study of Greek preadolescents
Q36993406Dietary intake of eicosapentaenoic and docosahexaenoic acids is linked to gray matter volume and cognitive function in elderly
Q48597352Differential effects of fluoxetine and venlafaxine on memory recognition: possible mechanisms of action
Q43956821Differential effects of melanocortin peptides on ingestive behaviour in rats: evidence against the involvement of MC(3) receptor in the regulation of food intake
Q43086424Differential expressions of melanocortin receptor subtypes in melanophores and xanthophores of barfin flounder
Q48707324Differential influence of a selective melanocortin MC4 receptor antagonist (HS014) on melanocortin-induced behavioral effects in rats
Q31027215Differential neural responses to food images in women with bulimia versus anorexia nervosa
Q31142509Differential regulation of nuclear receptors, neuropeptides and peptide hormones in the hypothalamus and pituitary of food restricted rats
Q48106033Differential role of the hippocampus, amygdala, and dorsal raphe nucleus in regulating feeding, memory, and anxiety-like behavioral responses to ghrelin
Q52181998Discovery of a novel superpotent and selective melanocortin-4 receptor antagonist (HS024): evaluation in vitro and in vivo.
Q29026417Discovery of novel melanocortin4receptor selective MSH analogues
Q46024340Dissecting signaling and functions of adhesion G protein-coupled receptors.
Q47908771Dissection of the Anti-Inflammatory Effect of the Core and C-Terminal (KPV) α-Melanocyte-Stimulating Hormone Peptides
Q48273808Diurnal rhythm of circulating nicotinamide phosphoribosyltransferase (Nampt/visfatin/PBEF): impact of sleep loss and relation to glucose metabolism
Q28573159Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced obesity phenotype in rats
Q52171186Downregulation of melanocortin receptors in brain areas involved in food intake and reward mechanisms in obese (OLETF) rats.
Q34570374Early vertebrate origin of melanocortin 2 receptor accessory proteins (MRAPs).
Q48452366Effect of repeated administration of prolactin releasing peptide on feeding behavior in rats
Q44179056Effects of melanocortin receptor ligands on ethanol intake and opioid peptide levels in alcohol-preferring AA rats
Q50643354Efficacy of antibody-based therapies to treat Alzheimer's disease: just a matter of timing?
Q47255884Epigenetic Changes in the CRH Gene are Related to Severity of Suicide Attempt and a General Psychiatric Risk Score in Adolescents
Q37050017Epigenomics of Total Acute Sleep Deprivation in Relation to Genome-Wide DNA Methylation Profiles and RNA Expression
Q30989416Evaluation of EST-data using the genome assembly
Q48298839Evaluation of behavioural effects of neural melanocortin receptor antagonists injected ICV and in VTA in rats
Q73800754Evaluation of the role for prolactin-releasing peptide in prolactin secretion induced by ether stress and suckling in the rat: comparison with vasoactive intestinal peptide
Q40747500Evidence for expression of melanocortin-1 receptor in human sebocytes in vitro and in situ
Q38548585Evidence for involvement of the melanocortin MC4 receptor in the effects of leptin on food intake and body weight
Q36836745Evidence indicating that the TM4, EL2, and TM5 of the melanocortin 3 receptor Do not participate in ligand binding
Q32038933Evidence indicating that the extracellular loops of the mouse MC5 receptor do not participate in ligand binding
Q74312014Evidence that alpha-MSH induced grooming is not primarily mediated by any of the cloned melanocortin receptors
Q73192583Evidence that melanocortin 4 receptor mediates hemorrhagic shock reversal caused by melanocortin peptides
Q38550959Evidence that orexigenic effects of melanocortin 4 receptor antagonist HS014 are mediated by neuropeptide Y.
Q72989376Evidence that physiological levels of circulating leptin exert a stimulatory effect on luteinizing hormone and prolactin surges in rats
Q44987175Evidence that the effect of melanocortins on female sexual behavior in preoptic area is mediated by the MC3 receptor; Participation of nitric oxide
Q33218132Evolutionary conservation of the structural, pharmacological, and genomic characteristics of the melanocortin receptor subtypes
Q35639967Evolutionary hierarchy of vertebrate-like heterotrimeric G protein families
Q38090789Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects
Q36125439Expansion of the superfamily of G-protein-coupled receptors in chordates
Q47724483Experimenter gender and replicability in science
Q44099896Exposure to a high-fat high-sugar diet causes strong up-regulation of proopiomelanocortin and differentially affects dopamine D1 and D2 receptor gene expression in the brainstem of rats
Q51331572Exposure to bisphenol A affects lipid metabolism in Drosophila melanogaster.
Q36322478Expression levels of genes encoding melanin concentrating hormone (MCH) and MCH receptor change in taste aversion, but MCH injections do not alleviate aversive responses
Q41204619Expression of functional melanocortin 1 receptors in insect cells
Q21093337Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat
Q33328978Extensive neuroadaptive changes in cortical gene-transcript expressions of the glutamate system in response to repeated intermittent MDMA administration in adolescent rats
Q51321454Fat mass and obesity-associated gene (FTO) is linked to higher plasma levels of the hunger hormone ghrelin and lower serum levels of the satiety hormone leptin in older adults.
Q37981392Feed-forward mechanisms: addiction-like behavioral and molecular adaptations in overeating
Q48959431Feeding responses to a melanocortin agonist and antagonist in obesity induced by a palatable high-fat diet
Q44028436Food conversion is transiently affected during 4-week chronic administration of melanocortin agonist and antagonist in rats
Q48132870Food deprivation increases the expression of melanocortin-4 receptor in the liver of barfin flounder, Verasper moseri
Q47822460Formation of new genes explains lower intron density in mammalian Rhodopsin G protein-coupled receptors.
Q28757328Functional characterization of two melanocortin (MC) receptors in lamprey showing orthology to the MC1 and MC4 receptor subtypes
Q34075916Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway
Q31149012Functional role, structure, and evolution of the melanocortin-4 receptor
Q21284069Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae
Q48673660Further evidence for a significant participation of the melanocortin 4 receptor in the preovulatory prolactin surge in the rat.
Q33274287Further evidence for ancient role of ACTH peptides at melanocortin (MC) receptors; pharmacology of dogfish and lamprey peptides at dogfish MC receptors
Q28369661Further pharmacological characterization of the selective melanocortin 4 receptor antagonist HS014: comparison with SHU9119
Q38047341G protein-coupled receptor deorphanizations
Q33247332G protein-coupled receptors in regulation of body weight
Q35513187Gabaergic control of anxiety-like behavior, but not food intake, induced by ghrelin in the intermediate medial mesopallium of the neonatal chick
Q61812344General Principles of Neuronal Co-transmission: Insights From Multiple Model Systems
Q34430272Genetic algorithm for large-scale maximum parsimony phylogenetic analysis of proteins
Q33962485Genetic and expression studies of SMN2 gene in Russian patients with spinal muscular atrophy type II and III
Q35663970Genetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and children
Q34123271Genome wide analysis reveals association of a FTO gene variant with epigenetic changes
Q35204587Genome-wide analysis reveals DNA methylation markers that vary with both age and obesity
Q38492972Genome-wide analysis shows association of epigenetic changes in regulators of Rab and Rho GTPases with spinal muscular atrophy severity
Q48278690Ghrelin and memory: differential effects on acquisition and retrieval
Q35304921Ghrelin effects expression of several genes associated with depression-like behavior
Q36808343Ghrelin in the CNS: from hunger to a rewarding and memorable meal?
Q34529618Ghrelin increases anxiety-like behavior and memory retention in rats
Q48426698Ghrelin increases memory consolidation through hippocampal mechanisms dependent on glutamate release and NR2B-subunits of the NMDA receptor
Q48208411Ghrelin induced memory facilitation implicates nitric oxide synthase activation and decrease in the threshold to promote LTP in hippocampal dentate gyrus
Q48960651Ghrelin inhibited serotonin release from hippocampal slices
Q33522779Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression
Q45224305Growth hormone-releasing hormone improves cognitive function in older adults: sleep on it.
Q33193594High Affinity Agonistic Metal Ion Binding Sites within the Melanocortin 4 Receptor Illustrate Conformational Change of Transmembrane Region 3
Q40111942High diversity in functional properties of melanocortin 1 receptor (MC1R) in divergent primate species is more strongly associated with phylogeny than coat color
Q40760828High leptin levels are associated with migraine with aura
Q37423664Higher resting-state activity in reward-related brain circuits in obese versus normal-weight females independent of food intake
Q42007006Highly diversified expansions shaped the evolution of membrane bound proteins in metazoans
Q48858222Hippocampal effects of neuronostatin on memory, anxiety-like behavior and food intake in rats
Q51532179Hyperphagia modifies FA profiles of plasma phospholipids, plasma FFA, and adipose tissue TAG.
Q24643901Hypothalamic FTO is associated with the regulation of energy intake not feeding reward
Q48014235IL-1β reduces GluA1 phosphorylation and its surface expression during memory reconsolidation and α-melanocyte-stimulating hormone can modulate these effects
Q56920902Identification and analysis of functionally important amino acids in human purinergic 12 receptor using a Saccharomyces cerevisiae expression system
Q34345483Identification of distant Agouti-like sequences and re-evaluation of the evolutionary history of the Agouti-related peptide (AgRP).
Q39731758Identification of domains responsible for specific membrane transport and ligand specificity of the ACTH receptor (MC2R).
Q28570382Identification of neurotransmitter receptor genes involved in alcohol self-administration in the rat prefrontal cortex, hippocampus and amygdala
Q33261106Identification of novel splice variants of Adhesion G protein-coupled receptors
Q35228807Identification of somatostatin receptor type 5 gene polymorphisms associated with acromegaly
Q33472933Impact of nandrolone decanoate on gene expression in endocrine systems related to the adverse effects of anabolic androgenic steroids
Q35879058Impaired insulin sensitivity as indexed by the HOMA score is associated with deficits in verbal fluency and temporal lobe gray matter volume in the elderly
Q35191447Implication of coronin 7 in body weight regulation in humans, mice and flies
Q35040994Increased impulsivity in response to food cues after sleep loss in healthy young men
Q33231912Increased mRNA levels of tyrosine hydroxylase and dopamine transporter in the VTA of male rats after chronic food restriction
Q34673108Increased prefrontal and parahippocampal activation with reduced dorsolateral prefrontal and insular cortex activation to food images in obesity: a meta-analysis of fMRI studies
Q34170681Independent HHsearch, Needleman--Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families
Q38747140Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control study
Q35129664Insights into the origin of nematode chemosensory GPCRs: putative orthologs of the Srw family are found across several phyla of protostomes
Q26314671Insulin receptor-like ectodomain genes and splice variants are found in both arthropods and human brain cDNA
Q48799793Insulin to treat Alzheimer's disease: just follow your nose?
Q47752195Interleukin-1β-induced memory reconsolidation impairment is mediated by a reduction in glutamate release and zif268 expression and α-melanocyte-stimulating hormone prevented these effects
Q37789844Intranasal insulin as a therapeutic option in the treatment of cognitive impairments
Q24619063Intranasal insulin enhances postprandial thermogenesis and lowers postprandial serum insulin levels in healthy men
Q47815013Intranasal insulin in Alzheimer's disease: Food for thought
Q37142166Intranasal treatment of central nervous system dysfunction in humans
Q33392384Inverse association of high-fat diet preference and anxiety-like behavior: a putative role for urocortin 2.
Q73287035Involvement of prolactin-releasing peptide in the preovulatory luteinizing hormone and prolactin surges in the rat
Q27311525Involvement of the neutral amino acid transporter SLC6A15 and leucine in obesity-related phenotypes
Q21146631Kiwi genome provides insights into evolution of a nocturnal lifestyle
Q37470916Late-life alcohol consumption and cognitive function in elderly men.
Q36609868Late-life obesity is associated with smaller global and regional gray matter volumes: a voxel-based morphometric study
Q38892773Learning and sleep-dependent consolidation of spatial and procedural memories are unaltered in young men under a fixed short sleep schedule
Q36293938Limbic-thalamo-cortical projections and reward-related circuitry integrity affects eating behavior: A longitudinal DTI study in adolescents with restrictive eating disorders
Q34147614Long evolutionary conservation and considerable tissue specificity of several atypical solute carrier transporters
Q42958574Long term orexigenic effect of a novel melanocortin 4 receptor selective antagonist
Q54199823Long-term oral melatonin administration reduces ethanol-induced increases in duodenal mucosal permeability and motility in rats.
Q35997131Longitudinal genome-wide methylation study of Roux-en-Y gastric bypass patients reveals novel CpG sites associated with essential hypertension
Q38372259Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction
Q74473939MC(3) receptors are involved in the protective effect of melanocortins in myocardial ischemia/reperfusion-induced arrhythmias
Q45959723MDMA (Ecstasy) decreases the number of neurons and stem cells in embryonic cortical cultures.
Q46772314Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes
Q41250598Major pharmacological distinction of the ACTH receptor from other melanocortin receptors
Q30488409Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers
Q21093241Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin
Q48933198Mediterranean diet habits in older individuals: associations with cognitive functioning and brain volumes
Q48580629Melanin-concentrating hormone (MCH) reverts the behavioral effects induced by inescapable stress
Q48709023Melanocortin 4 receptor activation inhibits presynaptic N-type calcium channels in amygdaloid complex neurons
Q38721086Melanocortin 4 receptor constitutive activity inhibits L-type voltage-gated calcium channels in neurons
Q48313356Melanocortin peptides affect the motivation to feed in rainbow trout (Oncorhynchus mykiss).
Q33935621Melanocortins and feeding behavior.
Q47941139Methylation of HPA axis related genes in men with hypersexual disorder
Q47926577Modeling of the three-dimensional structure of the human melanocortin 1 receptor, using an automated method and docking of a rigid cyclic melanocyte-stimulating hormone core peptide
Q46873444Molecular mechanisms involved in interleukin 1-beta (IL-1β)-induced memory impairment. Modulation by alpha-melanocyte-stimulating hormone (α-MSH).
Q30909532Molecular mechanisms underlying anorexia nervosa: focus on human gene association studies and systems controlling food intake
Q33442603Motivation for sucrose in sated rats is predicted by low anxiety-like behavior
Q48010350NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition
Q27334613Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans
Q33260352New melanocortin 1 receptor binding motif based on the C-terminal sequence of alpha-melanocyte-stimulating hormone
Q21564050Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship
Q43823221Nitric oxide mediates leptin-induced preovulatory luteinizing hormone and prolactin surges in rats
Q51549199Normalization of circulating leptin levels by fasting improves the reproductive function in obese OLETF female rats.
Q46365002Novel genetic variant in FTO influences insulin levels and insulin resistance in severely obese children and adolescents
Q28215107Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions
Q30884830Novel selective melanocortin 4 receptor antagonist induces food intake after peripheral administration
Q46809046Obsessive-compulsivity and working memory are associated with differential prefrontal cortex and insula activation in adolescents with a recent diagnosis of an eating disorder
Q31090756One melanocortin 4 and two melanocortin 5 receptors from zebrafish show remarkable conservation in structure and pharmacology
Q37871132Opioids as facilitators of feeding: can any food be rewarding?
Q44798112Orexigenic effect of the melanocortin MC4 receptor antagonist HS014 is inhibited only partially by neuropeptide Y Y1 receptor selective antagonists
Q28249624Origin of the prolactin-releasing hormone (PRLH) receptors: evidence of coevolution between PRLH and a redundant neuropeptide Y receptor during vertebrate evolution
Q64045406Orphan Drugs and Their Impact on Pharmaceutical Development
Q57469670Orphan Drugs and Their Impact on Pharmaceutical Development: (Trends in Pharmacological Sciences 39, 525-535, 2018)
Q34188589Oxytocin as feeding inhibitor: maintaining homeostasis in consummatory behavior
Q35182241Patients lacking sustainable long-term weight loss after gastric bypass surgery show signs of decreased inhibitory control of prepotent responses
Q50784100Pharmacological characterization of loss of function mutations of the human melanocortin 1 receptor that are associated with red hair.
Q36125521Pharmacological characterization of melanocortin receptors in fish suggests an important role for ACTH.
Q31068244Pharmacological comparison of rat and human melanocortin 3 and 4 receptors in vitro
Q44390557Pivotal roles of alpha-melanocyte-stimulating hormone and the melanocortin 4 receptor in leptin stimulation of prolactin secretion in rats
Q34357877Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes
Q70464990Polyunsaturated fatty acids in heart muscle and alpha 1-adrenoceptor binding properties
Q38291884Postnatal profile of plasma leptin concentrations in male and female rats: relation with the maturation of the pituitary-gonadal axis
Q34593002Potato (Solanum tuberosum) juice exerts an anticonvulsant effect in mice through binding to GABA receptors
Q42695423Presence of melanocortin (MC4) receptor in spiny dogfish suggests an ancient vertebrate origin of central melanocortin system
Q37231663Psychological intervention with working memory training increases basal ganglia volume: A VBM study of inpatient treatment for methamphetamine use.
Q48479239Quantitative mapping shows that serotonin rather than dopamine receptor mRNA expressions are affected after repeated intermittent administration of MDMA in rat brain
Q37143865Recurrent Sleep Fragmentation Induces Insulin and Neuroprotective Mechanisms in Middle-Aged Flies
Q28581807Reduced activity of monoamine oxidase in the rat brain following repeated nandrolone decanoate administration
Q60045131Reduced resting-state connectivity in areas involved in processing of face-related social cues in female adolescents with atypical anorexia nervosa
Q35877541Reduced vasopressin receptors activation mediates the anti-depressant effects of fluoxetine and venlafaxine in bulbectomy model of depression
Q44355418Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor
Q34727969Remarkable similarities between the hemichordate (Saccoglossus kowalevskii) and vertebrate GPCR repertoire
Q31139639Remarkable synteny conservation of melanocortin receptors in chicken, human, and other vertebrates
Q42628774Repeated intermittent MDMA binges reduce DAT density in mice and SERT density in rats in reward regions of the adolescent brain
Q35215346Replacement of short segments within transmembrane domains of MC2R disrupts retention signal
Q42708624Reply to Braasch and Postlethwait: Evolutionary origin of the teleost A2 agouti genes (agouti signaling protein 2 and agouti-related protein 2) remains unclear
Q48225019Response to Leusink et al.
Q36587113Resting-State Brain and the FTO Obesity Risk Allele: Default Mode, Sensorimotor, and Salience Network Connectivity Underlying Different Somatosensory Integration and Reward Processing between Genotypes
Q41141122Resting-state brain connectivity changes in obese women after Roux-en-Y gastric bypass surgery: A longitudinal study
Q35753625Restraint of appetite and reduced regional brain volumes in anorexia nervosa: a voxel-based morphometric study
Q48337234Role of MC4 receptors in the depressor and bradycardic effects of α-MSH in the nucleus tractus solitarii of the rat
Q40540041Roles of the melanocortin-4 receptor in antipyretic and hyperthermic actions of centrally administered alpha-MSH.
Q35120125Roux-en Y gastric bypass surgery induces genome-wide promoter-specific changes in DNA methylation in whole blood of obese patients
Q30493384SPRIT: Identifying horizontal gene transfer in rooted phylogenetic trees
Q28266971Scrutinizing the FTO locus: compelling evidence for a complex, long-range regulatory context
Q74424364Selective antagonist for the melanocortin 4 receptor (HS014) increases food intake in free-feeding rats
Q32052313Selective properties of C- and N-terminals and core residues of the melanocyte-stimulating hormone on binding to the human melanocortin receptor subtypes
Q48327418Selective serotonin reuptake inhibitor (fluoxetine) decreases the effects of ghrelin on memory retention and food intake
Q73489059Selectivity of [Phe-I7], [Ala6], and [D-Ala4,Gln5,Tyr6] substituted ACTH(4-10) analogues for the melanocortin receptors
Q36889306Selectivity of cyclic [D-Nal7] and [D-Phe7] substituted MSH analogues for the melanocortin receptor subtypes
Q48013471Self-reported sleep disturbance is associated with Alzheimer's disease risk in men.
Q46530674Sensitization to nicotine significantly decreases expression of GABA transporter GAT-1 in the medial prefrontal cortex
Q28185006Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives
Q54170999Sex matters: Report experimenter gender.
Q36340675Short Sleep Makes Declarative Memories Vulnerable to Stress in Humans
Q60044954Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals
Q47396099Sleep restriction alters plasma endocannabinoids concentrations before but not after exercise in humans
Q38305337Stimulation of prolactin secretion by chronic, but not acute, administration of leptin in the rat.
Q29616716Structural diversity of G protein-coupled receptors and significance for drug discovery
Q44574981Structural study of melanocortin peptides by fluorescence spectroscopy: identification of beta-(2-naphthyl)-D-alanine as a fluorescent probe
Q48616851Subliminal food images compromise superior working memory performance in women with restricting anorexia nervosa
Q30609885Subliminal versus supraliminal stimuli activate neural responses in anterior cingulate cortex, fusiform gyrus and insula: a meta-analysis of fMRI studies
Q31123294Subtype selective binding properties of substituted linear melanocyte stimulating hormone analogues
Q36125537Subtype-specific pharmacological properties of the melanocortin receptors in chicken
Q42163238Sweet taste perception not altered after acute sleep deprivation in healthy young men
Q33373826The Adhesion GPCR GPR125 is specifically expressed in the choroid plexus and is upregulated following brain injury
Q47070969The Drosophila small GTPase Rac2 is required for normal feeding and mating behaviour
Q38698055The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum and the arcuate nucleus
Q33245469The G protein-coupled receptor subset of the chicken genome
Q33400100The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents
Q33300185The G protein-coupled receptor subset of the rat genome
Q29547321The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints
Q34997600The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals
Q31165781The GRAFS classification system of G-protein coupled receptors in comparative perspective
Q34272482The MAP2K5-linked SNP rs2241423 is associated with BMI and obesity in two cohorts of Swedish and Greek children
Q33631545The Obesity-Linked Gene Nudt3 Drosophila Homolog Aps Is Associated With Insulin Signaling
Q35654649The Orphan G Protein-Coupled Receptor Gene GPR178 Is Evolutionary Conserved and Altered in Response to Acute Changes in Food Intake
Q36128057The Role of FTO and Vitamin D for the Weight Loss Effect of Roux-en-Y Gastric Bypass Surgery in Obese Patients
Q41996915The Role of Working Memory for Cognitive Control in Anorexia Nervosa versus Substance Use Disorder
Q28535388The STK33-linked SNP rs4929949 is associated with obesity and BMI in two independent cohorts of Swedish and Greek children
Q30831697The adhesion GPCRs: a unique family of G protein-coupled receptors with important roles in both central and peripheral tissues
Q21283861The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors
Q28579153The anabolic androgenic steroid nandrolone decanoate affects mRNA expression of dopaminergic but not serotonergic receptors
Q33517869The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924.
Q21134765The dispanins: a novel gene family of ancient origin that contains 14 human members
Q38135497The druggable genome: Evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication
Q33786381The early origin of melanocortin receptors, agouti-related peptide, agouti signalling peptide, and melanocortin receptor-accessory proteins, with emphasis on pufferfishes, elephant shark, lampreys, and amphioxus
Q24292706The evolutionary history and tissue mapping of GPR123: specific CNS expression pattern predominantly in thalamic nuclei and regions containing large pyramidal cells
Q28308157The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men
Q28277413The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste(1) and other related G protein-coupled receptors
Q24297111The human and mouse repertoire of the adhesion family of G-protein-coupled receptors
Q33841813The impact of cognitive training in substance use disorder: the effect of working memory training on impulse control in methamphetamine users
Q38038868The impact of intronic single nucleotide polymorphisms and ethnic diversity for studies on the obesity gene FTO.
Q39668153The influence of active and passive smoking during pregnancy on umbilical cord blood levels of vitamins A and E and neonatal anthropometric indices
Q48260828The melanin-concentrating hormone receptor 2 (MCH-R2) mediates the effect of MCH to control body color for background adaptation in the barfin flounder
Q41077921The melanocortin 1, 3, 4 or 5 receptors do not have a binding epitope for ACTH beyond the sequence of alpha-MSH.
Q38325791The melanocortin 4 receptor mediates leptin stimulation of luteinizing hormone and prolactin surges in steroid-primed ovariectomized rats
Q31118689The melanocortin receptor subtypes in chicken have high preference to ACTH-derived peptides
Q40604442The melanocortin system in Fugu: determination of POMC/AGRP/MCR gene repertoire and synteny, as well as pharmacology and anatomical distribution of the MCRs
Q28265784The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain
Q21261510The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children
Q21134911The origin of GPCRs: identification of mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in fungi
Q36125496The phylogenetic relationship of the glutamate and pheromone G-protein-coupled receptors in different vertebrate species
Q34254198The physiological role of melanocortin receptors
Q46543237The relative impact of chronic food restriction and acute food deprivation on plasma hormone levels and hypothalamic neuropeptide expression
Q44163792The repertoire of G-protein-coupled receptors in fully sequenced genomes
Q46416819The repertoire of trace amine G-protein-coupled receptors: large expansion in zebrafish
Q34463651The role of G protein-coupled receptors in the early evolution of neurotransmission and the nervous system
Q33304713The role of hypothalamic peptide gene expression in alcohol self-administration behavior
Q73048703The role of melanocortin receptors in sexual behavior in female rats
Q48417849The role of the melanocortin system and the melanocortin-4 receptor in ring dove (Streptopelia risoria) feeding behavior
Q28301865The solute carrier families have a remarkably long evolutionary history with the majority of the human families present before divergence of Bilaterian species
Q24293663There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini
Q31053914Thinking about eating food activates visual cortex with reduced bilateral cerebellar activation in females with anorexia nervosa: an fMRI study
Q48417203To press or not to press? Differential receptor expression and response to novelty in rats learning an operant response for reward
Q49122981Tonic inhibition of food intake during inactive phase is reversed by the injection of the melanocortin receptor antagonist into the paraventricular nucleus of the hypothalamus and central amygdala of the rat.
Q35974649Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome
Q34205159Trends in the exploitation of novel drug targets
Q38830058Two hours of evening reading on a self-luminous tablet vs. reading a physical book does not alter sleep after daytime bright light exposure
Q33215001Unusual genomic structure: melanocortin receptors in Fugu
Q33830620Watching TV and food intake: the role of content
Q38012356What model organisms and interactomics can reveal about the genetics of human obesity
Q42611861Withdrawal from free-choice high-fat high-sugar diet induces craving only in obesity-prone animals
Q46640116[3H]RS79948-197 binding to human, rat, guinea pig and pig alpha2A-, alpha2B- and alpha2C-adrenoceptors. Comparison with MK912, RX821002, rauwolscine and yohimbine
Q35909178mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts
Q38778196microRNA-192 suppresses the expression of the farnesoid X receptor

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