scholarly article | Q13442814 |
P50 | author | Nathan Pennock | Q42771253 |
Pepper J Schedin | Q59160451 | ||
P2093 | author name string | Elizabeth Mitchell | |
Courtney Betts | |||
Qiuchen Guo | |||
P2860 | cites work | Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism | Q24600173 |
Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis | Q24610450 | ||
Mammary gland development | Q24629797 | ||
Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine | Q24648636 | ||
A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) | Q24677007 | ||
Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium | Q24679838 | ||
Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3 | Q24794211 | ||
Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression | Q24794250 | ||
Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathway | Q26797238 | ||
Platelet-derived CXCL12 regulates monocyte function, survival, differentiation into macrophages and foam cells through differential involvement of CXCR4-CXCR7 | Q27329947 | ||
Complexities of TGF-β targeted cancer therapy | Q27693607 | ||
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells | Q27860620 | ||
Mechanisms of TGF-beta signaling from cell membrane to the nucleus | Q27860785 | ||
Induction of intestinal Th17 cells by segmented filamentous bacteria | Q28131638 | ||
IL-13 and TH2 cytokine exposure triggers matrix metalloproteinase 7-mediated Fas ligand cleavage from bronchial epithelial cells | Q39681261 | ||
The immune tolerance of cancer is mediated by IDO that is inhibited by COX-2 inhibitors through regulatory T cells | Q39869179 | ||
DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death. | Q39937447 | ||
IKKbeta/2 induces TWEAK and apoptosis in mammary epithelial cells | Q40300890 | ||
Celecoxib Alters the Intestinal Microbiota and Metabolome in Association with Reducing Polyp Burden | Q40608521 | ||
TGF-beta1-mediated fibroblast-myofibroblast terminal differentiation-the role of Smad proteins | Q40676876 | ||
Th2 cell membrane factors in association with IL-4 enhance matrix metalloproteinase-1 (MMP-1) while decreasing MMP-9 production by granulocyte-macrophage colony-stimulating factor-differentiated human monocytes. | Q40878546 | ||
Fibronectin fragments induce MMP activity in mouse mammary epithelial cells: evidence for a role in mammary tissue remodeling. | Q40900586 | ||
DAP-kinase participates in TNF-alpha- and Fas-induced apoptosis and its function requires the death domain | Q40942632 | ||
The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function | Q41119639 | ||
A phase III study of belagenpumatucel-L, an allogeneic tumour cell vaccine, as maintenance therapy for non-small cell lung cancer. | Q41474859 | ||
Mechanisms of TGF-beta-induced cell cycle arrest | Q41731272 | ||
Apoptotic cell death and tissue remodelling during mouse mammary gland involution | Q42462200 | ||
Immunosuppression induced by immature dendritic cells is mediated by TGF-beta/IL-10 double-positive CD4+ regulatory T cells | Q42915023 | ||
Mechanoregulation of the Myofibroblast in Wound Contraction, Scarring, and Fibrosis: Opportunities for New Therapeutic Intervention | Q43159830 | ||
Quantitative extracellular matrix proteomics to study mammary and liver tissue microenvironments. | Q44638329 | ||
CXCL12-CXCR4 promotes proliferation and invasion of pancreatic cancer cells | Q45412550 | ||
Transforming growth factor-beta regulates human retinal pigment epithelial cell phagocytosis by influencing a protein kinase C-dependent pathway. | Q45937155 | ||
Epithelial cells remove apoptotic epithelial cells during post-lactation involution of the mouse mammary gland | Q46868007 | ||
Transforming growth factor beta3 induces cell death during the first stage of mammary gland involution. | Q52167469 | ||
Cell death by apoptosis during involution of the lactating breast in mice and rats. | Q52487735 | ||
Leukemia inhibitory factor induces apoptosis of the mammary epithelial cells and participates in mouse mammary gland involution. | Q54096126 | ||
Macrophages are crucial for epithelial cell death and adipocyte repopulation during mammary gland involution. | Q54336220 | ||
Smad4 signalling in T cells is required for suppression of gastrointestinal cancer. | Q54462818 | ||
Divergent effects of interleukin-4 and interferon-gamma on macrophage-derived chemokine production: an amplification circuit of polarized T helper 2 responses | Q59713952 | ||
Programmed cell death during mammary tissue involution induced by weaning, litter removal, and milk stasis | Q71556998 | ||
Transforming growth factor beta 1 functions in monocytic differentiation of hematopoietic cells through autocrine and paracrine mechanisms | Q71804661 | ||
Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease | Q73542905 | ||
Mouse mammary gland involution is associated with cytochrome c release and caspase activation | Q74014346 | ||
TGF-beta induces apoptosis through Smad-mediated expression of DAP-kinase | Q77342591 | ||
Elimination of colon cancer in germ-free transforming growth factor beta 1-deficient mice | Q78532668 | ||
Janus Kinase 1 Is Essential for Inflammatory Cytokine Signaling and Mammary Gland Remodeling. | Q37122579 | ||
Cancer as an overhealing wound: an old hypothesis revisited | Q37217254 | ||
The TGF-beta paradox in human cancer: an update | Q37261631 | ||
An indispensable role for the chemokine receptor CCR10 in IgA antibody-secreting cell accumulation | Q37357265 | ||
TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes | Q37358159 | ||
The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment | Q37366259 | ||
Mechanisms by which the extracellular matrix and integrin signaling act to regulate the switch between tumor suppression and tumor promotion | Q37450854 | ||
Coordinated regulation of apoptosis and cell proliferation by transforming growth factor beta 1 in cultured uterine epithelial cells | Q37486376 | ||
Th17 cytokines and host-pathogen interactions at the mucosa: dichotomies of help and harm | Q37576442 | ||
Attenuation of TGF-β signaling supports tumor progression of a mesenchymal-like mammary tumor cell line in a syngeneic murine model | Q37626943 | ||
Targeting the TGFβ pathway for cancer therapy. | Q38274752 | ||
Prostaglandin E2 transactivates the colony-stimulating factor-1 receptor and synergizes with colony-stimulating factor-1 in the induction of macrophage migration via the mitogen-activated protein kinase ERK1/2. | Q38901572 | ||
TGF-β Signaling from Receptors to Smads | Q38906099 | ||
Non-steroidal anti-inflammatory drugs target the pro-tumorigenic extracellular matrix of the postpartum mammary gland | Q39429471 | ||
Altered TGF-β signaling in a subpopulation of human stromal cells promotes prostatic carcinogenesis. | Q39595827 | ||
Making sense of latent TGFbeta activation | Q28217641 | ||
Transforming growth factor-beta induces development of the T(H)17 lineage | Q28237370 | ||
SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer | Q28278952 | ||
Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction | Q28284617 | ||
Transforming growth factor-beta regulation of immune responses | Q28303115 | ||
Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation | Q28344659 | ||
Alternatively activated macrophages and collagen remodeling characterize the postpartum involuting mammary gland across species | Q28576808 | ||
Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan | Q28593378 | ||
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells | Q29614226 | ||
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF | Q29615685 | ||
TGF-beta-induced epithelial to mesenchymal transition | Q29619820 | ||
Non-Smad pathways in TGF-beta signaling | Q29620040 | ||
Molecular mechanism of TGF-beta1-induced apoptosis in HC11 mouse mammary epithelial cells (MEC). | Q30830601 | ||
Smad3 has a critical role in TGF-beta-mediated growth inhibition and apoptosis in colonic epithelial cells | Q33200320 | ||
The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland. | Q33588077 | ||
Early but not late pregnancy induces lifelong reductions in the proportion of mammary progesterone sensing cells and epithelial Wnt signaling | Q33739845 | ||
IgA ASC accumulation to the lactating mammary gland is dependent on VCAM-1 and alpha4 integrins | Q33771126 | ||
Transforming growth factor beta stimulates mammary adenocarcinoma cell invasion and metastatic potential | Q33825657 | ||
Collagen density promotes mammary tumor initiation and progression | Q33845553 | ||
Transforming growth factor beta1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis | Q33868837 | ||
Alpha-smooth muscle actin expression upregulates fibroblast contractile activity | Q33946717 | ||
Epithelial to mesenchymal transition by TGFβ-1 induction increases stemness characteristics in primary non small cell lung cancer cell line | Q33955042 | ||
Targeted mutations of transforming growth factor-beta genes reveal important roles in mouse development and adult homeostasis | Q34098867 | ||
Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways. | Q34103424 | ||
Cyclooxygenase-2-dependent lymphangiogenesis promotes nodal metastasis of postpartum breast cancer | Q34128977 | ||
Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2. | Q34206453 | ||
TGFβ signaling plays a critical role in promoting alternative macrophage activation | Q34306291 | ||
Transforming growth factor type beta induces monocyte chemotaxis and growth factor production | Q34339289 | ||
A phase I dose-escalation study to a predefined dose of a transforming growth factor-β1 monoclonal antibody (TβM1) in patients with metastatic cancer | Q34432864 | ||
Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization | Q34437556 | ||
Pregnancy-associated breast cancer and metastasis. | Q34504760 | ||
Transforming growth factor-beta signaling through the Smad pathway: role in extracellular matrix gene expression and regulation | Q34527773 | ||
TGF-beta promotes cell death and suppresses lactation during the second stage of mammary involution | Q34571586 | ||
Inflammation-mediated genetic and epigenetic alterations drive cancer development in the neighboring epithelium upon stromal abrogation of TGF-β signaling | Q34585721 | ||
The microRNA 424/503 cluster reduces CDC25A expression during cell cycle arrest imposed by transforming growth factor β in mammary epithelial cells | Q34592870 | ||
Cyclooxygenase-2 inhibition blocks M2 macrophage differentiation and suppresses metastasis in murine breast cancer model | Q34718187 | ||
T helper 17-associated cytokines are produced during antigen-specific inflammation in the mammary gland | Q34733857 | ||
Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks | Q34781947 | ||
Rat mammary extracellular matrix composition and response to ibuprofen treatment during postpartum involution by differential GeLC-MS/MS analysis. | Q34939050 | ||
Wound healing-like immune program facilitates postpartum mammary gland involution and tumor progression | Q35071581 | ||
Remodeling of the mammary microenvironment after lactation promotes breast tumor cell metastasis. | Q35087966 | ||
Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution | Q35140121 | ||
Mammary gland involution as an immunotherapeutic target for postpartum breast cancer. | Q35186471 | ||
Phagocytosis of apoptotic cells and the resolution of inflammation | Q35592696 | ||
Impaired cell death and mammary gland involution in the absence of Dock1 and Rac1 signaling. | Q35679546 | ||
Molecular Phenotype of Breast Cancer According to Time Since Last Pregnancy in a Large Cohort of Young Women | Q35820514 | ||
Prostaglandin E2 restrains macrophage maturation via E prostanoid receptor 2/protein kinase A signaling. | Q35849262 | ||
TGF-β promotes heterogeneity and drug resistance in squamous cell carcinoma | Q35871985 | ||
Loss of one Tgfbr2 allele in fibroblasts promotes metastasis in MMTV: polyoma middle T transgenic and transplant mouse models of mammary tumor progression | Q36026081 | ||
Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity. | Q36134167 | ||
Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation | Q36231523 | ||
Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts | Q36232642 | ||
TGF-beta regulation of epithelial cell proliferation | Q36351946 | ||
Stromelysin-1 regulates adipogenesis during mammary gland involution | Q36375815 | ||
Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation | Q36403539 | ||
Mammary epithelial cell phagocytosis downstream of TGF-β3 is characterized by adherens junction reorganization | Q36472463 | ||
T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements. | Q36503230 | ||
Transforming growth factor-beta in cancer and metastasis | Q36585129 | ||
Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells. | Q36614277 | ||
Down-regulation of TGF-beta receptors in human colorectal cancer: implications for cancer development | Q36620077 | ||
COX-2 modulates mammary tumor progression in response to collagen density. | Q36715145 | ||
Postpartum diagnosis demonstrates a high risk for metastasis and merits an expanded definition of pregnancy-associated breast cancer. | Q36718439 | ||
Fibroblast differentiation in wound healing and fibrosis | Q36729100 | ||
Formation and function of the myofibroblast during tissue repair | Q36735389 | ||
TGF-beta 1 stimulates cultured human fibroblasts to proliferate and produce tissue-like fibroplasia: a fibronectin matrix-dependent event | Q36844219 | ||
CXCL12/CXCR4 axis induces proliferation and invasion in human endometrial cancer | Q36879569 | ||
Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1 | Q37058555 | ||
Induction of TGF-β1 synthesis by macrophages in response to apoptotic cells requires activation of the scavenger receptor CD36 | Q37066594 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 1 | |
P577 | publication date | 2017-01-13 | |
P1433 | published in | Journal of Clinical Medicine | Q27724774 |
P1476 | title | Mammary Gland Involution Provides a Unique Model to Study the TGF-β Cancer Paradox | |
P478 | volume | 6 |
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Q47839645 | Linking Race, Cancer Outcomes, and Tissue Repair. |
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