Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy

scientific article

Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1013426659
P356DOI10.1038/CDD.2016.127
P932PMC publication ID5299714
P698PubMed publication ID27834955

P50authorKanneboyina NagarajuQ27662260
Jyoti K. JaiswalQ50648507
Marshall W HogarthQ51089640
Adam HornQ57881682
P2093author name stringKristy J Brown
Yetrib Hathout
Sree Rayavarapu
Shin'ichi Takeda
Aurelia Defour
Jack H Van der Meulen
Maria C Vila
P2860cites workRescue of dystrophic skeletal muscle by PGC-1α involves a fast to slow fiber type shift in the mdx mouseQ27310125
Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophyQ28546070
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic developmentQ28594513
Use of quantitative membrane proteomics identifies a novel role of mitochondria in healing injured muscles.Q30524775
Dysferlin regulates cell membrane repair by facilitating injury-triggered acid sphingomyelinase secretion.Q30582564
Alteration in calcium handling at the subcellular level in mdx myotubes.Q31456406
Dysferlin and the plasma membrane repair in muscular dystrophyQ33201061
Efficacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissuesQ33207057
Chronic administration of membrane sealant prevents severe cardiac injury and ventricular dilatation in dystrophic dogsQ33755416
Enhanced Ca²⁺ influx from STIM1-Orai1 induces muscle pathology in mouse models of muscular dystrophy.Q33784460
Imaging cell membrane injury and subcellular processes involved in repairQ33872310
Membrane sealant Poloxamer P188 protects against isoproterenol induced cardiomyopathy in dystrophin deficient miceQ33901556
Preclinical drug trials in the mdx mouse: assessment of reliable and sensitive outcome measuresQ33975979
Non-invasive optical imaging of muscle pathology in mdx mice using cathepsin caged near-infrared imagingQ34928429
VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effectsQ34981147
Decreased osmotic stability of dystrophin-less muscle cells from the mdx mouseQ35009267
Mechanism of Ca²⁺-triggered ESCRT assembly and regulation of cell membrane repairQ35099073
Dystrophin deficiency exacerbates skeletal muscle pathology in dysferlin-null miceQ35779807
How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouseQ35821127
Regulation of cytosolic calcium in skeletal muscle cells of the mdx mouse under conditions of stressQ35873884
Dystrophin and dysferlin double mutant mice: a novel model for rhabdomyosarcomaQ36025454
A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin.Q36232550
Mechanical function of dystrophin in muscle cellsQ36235185
Targeted disruption of exon 52 in the mouse dystrophin gene induced muscle degeneration similar to that observed in Duchenne muscular dystrophy.Q52527217
Contraction-induced injury to single permeabilized muscle fibers from mdx, transgenic mdx, and control mice.Q52541082
High resolution respirometry of permeabilized skeletal muscle fibers in the diagnosis of neuromuscular disorders.Q53964474
Dystrophin levels and clinical severity in Becker muscular dystrophy patients.Q54508616
Time course of changes in plasma membrane permeability in the dystrophin-deficient mdx mouseQ58487605
Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch.Q64981707
Changes in muscle plasma membranes in young mice with X chromosome-linked muscular dystrophy: a freeze-fracture studyQ68049296
Efficient recovery of dysferlin deficiency by dual adeno-associated vector-mediated gene transferQ82892069
Use of stable isotope labeling by amino acids in cell culture as a spike-in standard in quantitative proteomicsQ83366737
Peroxisome proliferator-activated receptor γ coactivator1- gene α transfer restores mitochondrial biomass and improves mitochondrial calcium handling in post-necrotic mdx mouse skeletal muscleQ84829768
Increased dysferlin expression in Duchenne muscular dystrophyQ95403251
Dystrophin protects the sarcolemma from stresses developed during muscle contractionQ36259954
Elusive sources of variability of dystrophin rescue by exon skippingQ36340978
Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse modelQ36351079
Stem and progenitor cells in skeletal muscle development, maintenance, and therapyQ36771273
Poloxamer 188 reduces the contraction-induced force decline in lumbrical muscles from mdx miceQ36805372
Identification of disease specific pathways using in vivo SILAC proteomics in dystrophin deficient mdx mouse.Q36832437
Mechanisms of muscle degeneration, regeneration, and repair in the muscular dystrophiesQ37276061
Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicatorsQ37327467
Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanismQ37419160
Exogenous cytochrome C restores myocardial cytochrome oxidase activity into the late phase of sepsisQ37673307
Muscular dystrophy in dysferlin-deficient mouse modelsQ38087717
Dystrophin abnormalities in Duchenne/Becker muscular dystrophyQ38768990
Chronic AMPK activation evokes the slow, oxidative myogenic program and triggers beneficial adaptations in mdx mouse skeletal muscleQ39527529
Autophagy regulates satellite cell ability to regenerate normal and dystrophic musclesQ39571496
Dominant-negative inhibition of Ca2+ influx via TRPV2 ameliorates muscular dystrophy in animal modelsQ39909880
Increased activity of calcium leak channels caused by proteolysis near sarcolemmal rupturesQ41752594
Involvement of TRPC in the abnormal calcium influx observed in dystrophic (mdx) mouse skeletal muscle fibersQ41882302
Post-natal induction of PGC-1α protects against severe muscle dystrophy independently of utrophin.Q41911490
Reciprocal amplification of ROS and Ca(2+) signals in stressed mdx dystrophic skeletal muscle fibers.Q42452644
Increased activity of calcium leak channels in myotubes of Duchenne human and mdx mouse originQ44177784
Effects of stretch-activated channel blockers on [Ca2+]i and muscle damage in the mdx mouse.Q45140549
Increased protein degradation results from elevated free calcium levels found in muscle from mdx miceQ46266620
Calcium entry through stretch-inactivated ion channels in mdx myotubesQ46603395
Dystrophic heart failure blocked by membrane sealant poloxamerQ46604988
Impaired mitochondrial oxidative phosphorylation in skeletal muscle of the dystrophin-deficient mdx mouseQ47878704
P275copyright licenseCreative Commons Attribution-NonCommercial-ShareAlike 4.0 InternationalQ42553662
P6216copyright statuscopyrightedQ50423863
P433issue2
P921main subjectmitochondrionQ39572
P304page(s)330-342
P577publication date2016-11-11
P1433published inCell Death & DifferentiationQ2943974
P1476titleMitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy
P478volume24

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cites work (P2860)
Q58606031A Screen Using iPSC-Derived Hepatocytes Reveals NAD as a Potential Treatment for mtDNA Depletion Syndrome
Q90414913CRISPR/Cas9-Based Dystrophin Restoration Reveals a Novel Role for Dystrophin in Bioenergetics and Stress Resistance of Muscle Progenitors
Q92147843DSS-induced damage to basement membranes is repaired by matrix replacement and crosslinking
Q44907195Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury
Q91237933Membrane Stabilization by Modified Steroid Offers a Potential Therapy for Muscular Dystrophy Due to Dysferlin Deficit
Q93385793Mitochondria-Targeted Drugs
Q97420407Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in mdx Mice
Q96954758Mitochondrial Function in Muscle Stem Cell Fates
Q46311660Mitochondrial redox signaling enables repair of injured skeletal muscle cells
Q90407716Modeling disease trajectory in Duchenne muscular dystrophy
Q96127087Motor axonopathies in a mouse model of Duchenne muscular dystrophy
Q57286631Muscle membrane integrity in Duchenne muscular dystrophy: recent advances in copolymer-based muscle membrane stabilizers
Q60049386Myoblasts rely on TAp63 to control basal mitochondria respiration
Q89767037Nutritional intervention with cyanidin hinders the progression of muscular dystrophy
Q88249085Observation of acetyl phosphate formation in mammalian mitochondria using real-time in-organelle NMR metabolomics
Q64110017PGC-1α overexpression partially rescues impaired oxidative and contractile pathophysiology following volumetric muscle loss injury
Q47151990Pharmacological inhibition of REV-ERB stimulates differentiation, inhibits turnover and reduces fibrosis in dystrophic muscle.
Q61796529Reduced mitochondrial respiration and increased calcium deposits in the EDL muscle, but not in soleus, from 12-week-old dystrophic mdx mice
Q55515149Skeletal Muscle Metabolism in Duchenne and Becker Muscular Dystrophy-Implications for Therapies.
Q60907638TAp73 regulates ATP7A: possible implications for ageing-related diseases
Q90661491TGF-β-driven muscle degeneration and failed regeneration underlie disease onset in a DMD mouse model
Q90750443Transcriptome changes during the initiation and progression of Duchenne Muscular Dystrophy in C. elegans
Q42634544Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle