Eribulin -- a review of preclinical and clinical studies.

scientific article published on 14 April 2011

Eribulin -- a review of preclinical and clinical studies. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.CRITREVONC.2011.03.002
P932PMC publication ID3954568
P698PubMed publication ID21493087
P5875ResearchGate publication ID51051314

P50authorUmang SwamiQ83863838
P2093author name stringSanjay Goel
Imran Chaudhary
Mohammad H Ghalib
P2860cites workEribulin binds at microtubule ends to a single site on tubulin to suppress dynamic instabilityQ24610709
Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphaseQ24657514
In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin BQ28202233
Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatmentQ28255226
The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growthQ28261808
Induction of morphological and biochemical apoptosis following prolonged mitotic blockage by halichondrin B macrocyclic ketone analog E7389Q28277346
Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity dataQ28292051
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancerQ29614302
Initial paclitaxel improves outcome compared with CMFP combination chemotherapy as front-line therapy in untreated metastatic breast cancerQ33330619
Randomized comparison of vinorelbine and melphalan in anthracycline-refractory advanced breast cancerQ33488625
Class III beta-tubulin expression and in vitro resistance to microtubule targeting agentsQ33630855
Docetaxel versus docetaxel alternating with gemcitabine as treatments of advanced breast cancer: final analysis of a randomised trialQ33812323
Phase II evaluation of eribulin mesylate (E7389, NSC 707389) in patients with metastatic or recurrent squamous cell carcinoma of the head and neck: Southwest Oncology Group trial S0618.Q33941497
Randomized phase III trial of ixabepilone plus capecitabine versus capecitabine in patients with metastatic breast cancer previously treated with an anthracycline and a taxaneQ33990883
Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancerQ34022546
Isolation and structure of the cell growth inhibitory constituents from the western Pacific marine sponge Axinella sp.Q34989416
Natural products which interact with tubulin in the vinca domain: maytansine, rhizoxin, phomopsin A, dolastatins 10 and 15 and halichondrin BQ35183246
Is class III beta-tubulin a predictive factor in patients receiving tubulin-binding agents?Q37073084
Phase II study of the halichondrin B analog eribulin mesylate in patients with locally advanced or metastatic breast cancer previously treated with an anthracycline, a taxane, and capecitabineQ37777290
Eribulin mesilate, a halichondrin B analogue, in the treatment of breast cancerQ37802209
The Place for Eribulin in the Treatment of Metastatic Breast CancerQ37811984
Tubulin-based antimitotic mechanism of E7974, a novel analogue of the marine sponge natural product hemiasterlinQ39787976
Comparison of the activities of the truncated halichondrin B analog NSC 707389 (E7389) with those of the parent compound and a proposed binding site on tubulin.Q40238368
Phase III trials of eribulin mesylate (E7389) in extensively pretreated patients with locally recurrent or metastatic breast cancerQ42653377
Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerizationQ42815194
Analysis of overall survival from a phase III study of ixabepilone plus capecitabine versus capecitabine in patients with MBC resistant to anthracyclines and taxanesQ43068334
Vinorelbine induces beta3-tubulin gene expression through an AP-1 Site.Q43297205
Eribulin mesylate pharmacokinetics in patients with solid tumors receiving repeated oral ketoconazoleQ43861920
Macromolecular interaction of halichondrin B analogues eribulin (E7389) and ER-076349 with tubulin by analytical ultracentrifugation.Q45935600
A phase I study of eribulin mesylate (E7389), a mechanistically novel inhibitor of microtubule dynamics, in patients with advanced solid malignancies.Q45976166
Phase I study of eribulin mesylate administered once every 21 days in patients with advanced solid tumors.Q45976200
Phase II study of eribulin mesylate, a halichondrin B analog, in patients with metastatic breast cancer previously treated with an anthracycline and a taxaneQ46059531
Delineation of the interactions between the chemotherapeutic agent eribulin mesylate (E7389) and human CYP3A4.Q46353411
Interaction of halichondrin B and homohalichondrin B with bovine brain tubulinQ48344692
Phase II study of eribulin mesylate (E7389) in patients with metastatic castration-resistant prostate cancer stratified by prior taxane therapy.Q51533397
Phase III Trial of Nanoparticle Albumin-Bound Paclitaxel Compared With Polyethylated Castor Oil–Based Paclitaxel in Women With Breast CancerQ56626150
Randomized Phase III Trial of Weekly Compared With Every-3-Weeks Paclitaxel for Metastatic Breast Cancer, With Trastuzumab for all HER-2 Overexpressors and Random Assignment to Trastuzumab or Not in HER-2 Nonoverexpressors: Final Results of Cancer anQ57578399
Phase III Trial Comparing Three Doses of Docetaxel for Second-Line Treatment of Advanced Breast CancerQ57580011
Halichondrins - antitumor polyether macrolides from a marine spongeQ62773345
Accelerated titration designs for phase I clinical trials in oncologyQ73598986
Comparative antitumor activities of halichondrins and vinblastine against human tumor xenograftsQ73982426
Gemcitabine plus vinorelbine versus vinorelbine monotherapy in patients with metastatic breast cancer previously treated with anthracyclines and taxanes: final results of the phase III Spanish Breast Cancer Research Group (GEICAM) trialQ79847220
P433issue2
P304page(s)163-184
P577publication date2011-04-14
P1433published inCritical Reviews in Oncology HematologyQ15724423
P1476titleEribulin -- a review of preclinical and clinical studies
P478volume81

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cites work (P2860)
Q36443858A phase I combination dose-escalation study of eribulin mesylate and gemcitabine in patients with advanced solid tumours: a study of the Princess Margaret Consortium
Q38837821Anti-Microtubule Drugs
Q26777317Antimitotic drugs in the treatment of cancer
Q50045537Bi-weekly eribulin therapy for metastatic breast cancer: a multicenter phase II prospective study (JUST-STUDY).
Q92854569Decreased Disposition of Anticancer Drugs Predominantly Eliminated via the Liver in Patients with Renal Failure
Q90554778Differential Morphological and Biochemical Recovery from Chemotherapy-Induced Peripheral Neuropathy Following Paclitaxel, Ixabepilone, or Eribulin Treatment in Mouse Sciatic Nerves
Q52603297Effect of eribulin on patients with metastatic breast cancer: multicenter retrospective observational study in Taiwan.
Q47628083Effectiveness and safety of eribulin mesylate: a new therapeutic option in the treatment of metastatic breast cancer.
Q41592750Eribulin alone or in combination with the PLK1 inhibitor BI 6727 triggers intrinsic apoptosis in Ewing sarcoma cell lines
Q90418687Eribulin as a Feasible and Safe Monotherapy in a Dialytic Pretreated Woman with Metastatic Breast Cancer: A Case Report
Q37654001Eribulin drug review
Q38686619Eribulin efficacy based on type of metastatic site: a real-life study in heavily pretreated metastatic breast cancer
Q26799328Eribulin in Cancer Treatment
Q39120142Eribulin in non-small cell lung cancer: challenges and potential strategies.
Q28074125Eribulin in the management of inoperable soft-tissue sarcoma: patient selection and survival
Q38213846Eribulin mesylate in the management of metastatic breast cancer and other solid cancers: a drug review
Q38267039Eribulin: a new-generation antimicrotubule agent in lung cancer therapy
Q38012442Eribulin: a novel cytotoxic chemotherapy agent
Q41988197Managing sarcoma: where have we come from and where are we going?
Q33815594Neuropathy-inducing effects of eribulin mesylate versus paclitaxel in mice with preexisting neuropathy
Q64253409Neurymenolide A, a Novel Mitotic Spindle Poison from the New Caledonian Rhodophyta
Q36181279Pharmacokinetics of eribulin mesylate in cancer patients with normal and impaired renal function
Q38220276Pneumonitis and pulmonary fibrosis associated with breast cancer treatments.
Q90476597Prospective Analysis of Patients with Metastatic Breast Cancer receiving Eribulin Mesylate as Second or More Lines of Chemotherapy: An Indian Experience
Q36273796Recent Advances in the Development of Antineoplastic Agents Derived from Natural Products
Q40241837Safety and tolerability of eribulin mesylate in patients with pretreated metastatic breast cancer
Q92669080Selectively high efficacy of eribulin against high-grade invasive recurrent and/or metastatic squamous cell carcinoma of the head and neck
Q46592179Synergistic effect of eribulin and CDK inhibition for the treatment of triple negative breast cancer.

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