scholarly article | Q13442814 |
P50 | author | Simone Fulda | Q21264686 |
P2093 | author name string | Manuela Hugle | |
Lilly Magdalena WeiΔ | |||
P2860 | cites work | Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosis | Q24317740 |
Eribulin binds at microtubule ends to a single site on tubulin to suppress dynamic instability | Q24610709 | ||
The Bcl-2 apoptotic switch in cancer development and therapy | Q24620437 | ||
BI 6727, a Polo-like kinase inhibitor with improved pharmacokinetic profile and broad antitumor activity | Q27655038 | ||
Eribulin in the management of inoperable soft-tissue sarcoma: patient selection and survival | Q28074125 | ||
Microtubules as a target for anticancer drugs | Q28253993 | ||
The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth | Q28261808 | ||
The clone wars - revenge of the metastatic rogue state: the sarcoma paradigm. | Q41865440 | ||
Contribution of Bcl-2 phosphorylation to Bak binding and drug resistance. | Q41906775 | ||
Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: implications for chemotherapy-induced peripheral neuropathy | Q42112858 | ||
The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells | Q42663433 | ||
Sensitivity of Ewing's sarcoma to TRAIL-induced apoptosis | Q43652159 | ||
Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer | Q43761430 | ||
Phase I study of eribulin mesylate administered once every 21 days in patients with advanced solid tumors. | Q45976200 | ||
Structural basis for the regulation of tubulin by vinblastine | Q46511115 | ||
Identification of a distinct class of vinblastine binding sites on microtubules | Q48386594 | ||
Eribulin versus dacarbazine in previously treated patients with advanced liposarcoma or leiomyosarcoma: a randomised, open-label, multicentre, phase 3 trial. | Q53175509 | ||
Expression, purification, crystallization, and biochemical characterization of a recombinant protein phosphatase. | Q54652530 | ||
Induction of morphological and biochemical apoptosis following prolonged mitotic blockage by halichondrin B macrocyclic ketone analog E7389 | Q28277346 | ||
Diagnosis and treatment of Ewing's sarcoma | Q28286292 | ||
The BCL-2 protein family: opposing activities that mediate cell death | Q29547380 | ||
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 | Q29616161 | ||
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry | Q29617253 | ||
Cell death: the significance of apoptosis | Q29617620 | ||
Apoptosis: controlled demolition at the cellular level | Q29620114 | ||
Changes in incidence and survival of Ewing sarcoma patients over the past 3 decades: Surveillance Epidemiology and End Results data. | Q31157886 | ||
Small interfering RNA library screen of human kinases and phosphatases identifies polo-like kinase 1 as a promising new target for the treatment of pediatric rhabdomyosarcomas | Q33514778 | ||
Cell cycle and apoptosis | Q34045686 | ||
Histone H3 phosphorylation and cell division | Q34290245 | ||
Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states | Q34406761 | ||
Initial testing (stage 1) of the Polo-like kinase inhibitor volasertib (BI 6727), by the Pediatric Preclinical Testing Program. | Q34561518 | ||
Initial testing (stage 1) of eribulin, a novel tubulin binding agent, by the pediatric preclinical testing program | Q34683835 | ||
Interactions of halichondrin B and eribulin with tubulin | Q35088820 | ||
Eribulin mesylate in the treatment of metastatic breast cancer | Q35699382 | ||
Interferon-gamma sensitizes resistant Ewing's sarcoma cells to tumor necrosis factor apoptosis-inducing ligand-induced apoptosis by up-regulation of caspase-8 without altering chemosensitivity | Q35855534 | ||
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy | Q36558024 | ||
Identification of synthetic lethality of PLK1 inhibition and microtubule-destabilizing drugs | Q36751562 | ||
Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death | Q37299645 | ||
ZEB2 Represses the Epithelial Phenotype and Facilitates Metastasis in Ewing Sarcoma | Q37424383 | ||
Eribulin -- a review of preclinical and clinical studies. | Q37637936 | ||
Integrating mechanisms of response and resistance against the tubulin binding agent Eribulin in preclinical models of osteosarcoma. | Q37699295 | ||
Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy | Q37776652 | ||
Eribulin mesylate, a novel microtubule inhibitor in the treatment of breast cancer | Q37873164 | ||
Peripheral neuropathy with microtubule-targeting agents: occurrence and management approach | Q37875324 | ||
Ewing sarcoma: clinical state-of-the-art | Q37980482 | ||
Ewing Sarcoma: Current Management and Future Approaches Through Collaboration | Q38573422 | ||
Synergistic induction of apoptosis by a polo-like kinase 1 inhibitor and microtubule-interfering drugs in Ewing sarcoma cells | Q38844740 | ||
Eribulin synergizes with Polo-like kinase 1 inhibitors to induce apoptosis in rhabdomyosarcoma | Q38881789 | ||
Bortezomib antagonizes microtubule-interfering drug-induced apoptosis by inhibiting G2/M transition and MCL-1 degradation | Q39058933 | ||
Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7. | Q39582682 | ||
Polo-like kinase 1 is a therapeutic target in high-risk neuroblastoma | Q39618381 | ||
Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest. | Q39696436 | ||
Identification of the major phosphorylation site in Bcl-xL induced by microtubule inhibitors and analysis of its functional significance | Q39923184 | ||
Comparison of the activities of the truncated halichondrin B analog NSC 707389 (E7389) with those of the parent compound and a proposed binding site on tubulin. | Q40238368 | ||
Polo-like kinase 1 inhibition sensitizes neuroblastoma cells for vinca alkaloid-induced apoptosis | Q41819580 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 32 | |
P407 | language of work or name | English | Q1860 |
P1104 | number of pages | 12 | |
P304 | page(s) | 52445-52456 | |
P577 | publication date | 2017-04-18 | |
P1433 | published in | Oncotarget | Q1573155 |
P1476 | title | Eribulin alone or in combination with the PLK1 inhibitor BI 6727 triggers intrinsic apoptosis in Ewing sarcoma cell lines | |
P478 | volume | 8 |
Search more.