Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation

scientific article published on 16 July 2016

Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.10636
P932PMC publication ID5312290
P698PubMed publication ID27449295

P2093author name stringJinfu Zhang
Weiwei Wang
Jingjing Wu
Hu Lei
Xiangyun Chen
Weilie Xiao
Wenli Gu
Hanzhang Xu
Yingli Wu
Caixia Tang
P2860cites workSUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxiaQ24299542
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Triptolide inhibits the proliferation of prostate cancer cells and down-regulates SUMO-specific protease 1 expressionQ28484018
Protein modification by SUMOQ29547919
Natural products as sources of new drugs over the 30 years from 1981 to 2010Q29616640
Genetic and proteomic evidence for roles of Drosophila SUMO in cell cycle control, Ras signaling, and early pattern formationQ33468445
SENP1 induces prostatic intraepithelial neoplasia through multiple mechanismsQ34056043
Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.Q34355711
Momordin Ic and oleanolic acid from Kochiae Fructus reduce carbon tetrachloride-induced hepatotoxicity in ratsQ34444993
Proton pump inhibitors enhance the effects of cytotoxic agents in chemoresistant epithelial ovarian carcinomaQ36544294
Intrinsic apoptotic pathway and G2/M cell cycle arrest involved in tubeimoside I-induced EC109 cell deathQ36967486
NAC-1, a potential stem cell pluripotency factor, contributes to paclitaxel resistance in ovarian cancer through inactivating Gadd45 pathwayQ37184393
TRAIL pathway is associated with inhibition of colon cancer by protopanaxadiolQ37316131
SUMOylation and De-SUMOylation: wrestling with life's processesQ37325310
Identification and characterization of a new chemotype of noncovalent SENP inhibitorsQ37341772
Biological role and prognostic significance of NAC1 in ovarian cancerQ37792443
Progression of metastatic castrate-resistant prostate cancer: impact of therapeutic intervention in the post-docetaxel spaceQ37868056
Sentrin/small ubiquitin-like modifier-specific protease 5 protects oral cancer cells from oxidative stress-induced apoptosisQ38883639
SUMO-specific protease 1 regulates pancreatic cancer cell proliferation and invasion by targeting MMP-9.Q38956991
SUMO-specific protease 1 promotes prostate cancer progression and metastasisQ39325271
Biological and clinical significance of NAC1 expression in cervical carcinomas: a comparative study between squamous cell carcinomas and adenocarcinomas/adenosquamous carcinomasQ39480123
SUMO-specific protease 1 regulates the in vitro and in vivo growth of colon cancer cells with the upregulated expression of CDK inhibitorsQ39525345
Induction of the SUMO-specific protease 1 transcription by the androgen receptor in prostate cancer cellsQ40068850
Transition zone PSA density improves the prostate cancer detection rate both in PSA 4.0-10.0 and 10.1-20.0 ng/ml in Chinese men.Q46035004
A novel mechanism for momordin Ic-induced HepG2 apoptosis: involvement of PI3K- and MAPK-dependent PPARγ activationQ46925565
Up-regulation of hypoxia-inducible factor 1alpha is an early event in prostate carcinogenesis.Q50933268
Momordin Ic induces HepG2 cell apoptosis through MAPK and PI3K/Akt-mediated mitochondrial pathways.Q52638332
Discovery of 1-[4-(N-benzylamino)phenyl]-3-phenylurea derivatives as non-peptidic selective SUMO-sentrin specific protease (SENP)1 inhibitorsQ58615236
Triterpenoid glycosides from the fruits of Kochia scopariaQ71538284
Acceleration of gastrointestinal transit by momordin Ic in mice: possible involvement of 5-hydroxytryptamine, 5-HT(2) receptors and prostaglandinsQ73626998
Structure-related inhibitory activity of oleanolic acid glycosides on gastric emptying in miceQ77370671
Roles of capsaicin-sensitive sensory nerves, endogenous nitric oxide, sulfhydryls, and prostaglandins in gastroprotection by momordin Ic, an oleanolic acid oligoglycoside, on ethanol-induced gastric mucosal lesions in ratsQ78030387
Effects of oleanolic acid glycosides on gastrointestinal transit and ileus in miceQ78068034
Ki67 immunohistochemistry: a valuable marker in prognostication but with a risk of misclassification: proliferation subgroups formed based on Ki67 immunoreactivity and standardized mitotic indexQ83302905
Antiproliferative Effects of Saponins from the Roots of Platycodon grandiflorum on Cultured Human Tumor CellsQ85182827
Important role of SUMOylation of Spliceosome factors in prostate cancer cellsQ87401469
P4510describes a project that usesImageJQ1659584
P433issue37
P407language of work or nameEnglishQ1860
P921main subjectprostate cancerQ181257
P304page(s)58995-59005
P577publication date2016-07-16
P1433published inOncotargetQ1573155
P1476titleMomordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation
P478volume7