Endocannabinoids: A Promising Impact for Traumatic Brain Injury.

scientific article published on 17 February 2017

Endocannabinoids: A Promising Impact for Traumatic Brain Injury. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FPHAR.2017.00069
P932PMC publication ID5314139
P698PubMed publication ID28261100

P50authorLesley D SchurmanQ56901184
P2093author name stringAron H Lichtman
P2860cites workChronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.Q22242243
Decompressive craniectomy for the treatment of refractory high intracranial pressure in traumatic brain injuryQ24244941
Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brainQ24299523
Brain monoglyceride lipase participating in endocannabinoid inactivationQ24533828
Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolaseQ24555807
Nonpsychotropic cannabinoid acts as a functional N-methyl-D-aspartate receptor blockerQ24601670
CB2 receptors in the brain: role in central immune functionQ24643895
A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerolQ24649418
Estradiol Decreases Cortical Reactive Astrogliosis after Brain Injury by a Mechanism Involving Cannabinoid ReceptorsQ59341018
A new perspective on cannabinoid signalling: complementary localization of fatty acid amide hydrolase and the CB1 receptor in rat brainQ64212085
Diffuse axonal injury in head injury: definition, diagnosis and gradingQ69698410
Fatty acid amide hydrolase substrate specificityQ73324250
Involvement of the cannabinoid CB2 receptor and its endogenous ligand 2-arachidonoylglycerol in oxazolone-induced contact dermatitis in miceQ79401094
Motor impairment after severe traumatic brain injury: A longitudinal multicenter studyQ80188117
Neuroprotection and reduction of glial reaction by cannabidiol treatment after sciatic nerve transection in neonatal ratsQ39360618
Recent Advances in the Chemistry of HashishQ39975059
Pharmacological modulation of the endocannabinoid system in a viral model of multiple sclerosis.Q40440754
N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesiaQ40672731
Factors affecting excitatory amino acid release following severe human head injuryQ40840971
Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptorsQ40935207
An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activityQ41012471
Comparative neuroprotective effects of cyclosporin A and NIM811, a nonimmunosuppressive cyclosporin A analog, following traumatic brain injuryQ41774918
O-Hydroxyacetamide Carbamates as a Highly Potent and Selective Class of Endocannabinoid Hydrolase InhibitorsQ41971391
Endocannabinoids modulate human blood-brain barrier permeability in vitroQ42107964
Statins increase neurogenesis in the dentate gyrus, reduce delayed neuronal death in the hippocampal CA3 region, and improve spatial learning in rat after traumatic brain injuryQ42384723
Effect of rosuvastatin on amnesia and disorientation after traumatic brain injury (NCT003229758).Q42439973
Amplitude/frequency of spontaneous mEPSC correlates to the degree of long-term depression in the CA1 region of the hippocampal sliceQ42480403
Does the neuroprotective role of anandamide display diurnal variations?Q42769645
Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegenerationQ43752352
Assessment of the role of CB1 receptors in cannabinoid anticonvulsant effectsQ43846366
Dexanabinol (HU-211) in the treatment of severe closed head injury: a randomized, placebo-controlled, phase II clinical trialQ43980213
Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivoQ44028862
Neuroscience. Stout guards of the central nervous systemQ44606611
‘Ischemic tolerance’ phenomenon detected in various brain regionsQ44805794
Diffusion tensor imaging and volumetric analysis of the ventral striatum in adults with traumatic brain injury.Q44815593
Segregation of two endocannabinoid-hydrolyzing enzymes into pre- and postsynaptic compartments in the rat hippocampus, cerebellum and amygdala.Q44963304
CB1 cannabinoid receptors are involved in neuroprotection via NF-kappa B inhibitionQ45281373
Late mortality after severe traumatic brain injury in New South Wales: a multicentre studyQ46029334
Pretreatment with electroacupuncture induces rapid tolerance to focal cerebral ischemia through regulation of endocannabinoid systemQ46048076
Natural cannabinoids improve dopamine neurotransmission and tau and amyloid pathology in a mouse model of tauopathy.Q46123071
The development of acute lung injury is associated with worse neurologic outcome in patients with severe traumatic brain injuryQ46193912
2-Arachidonoylglycerol, an endogenous cannabinoid receptor agonist, in various rat tissues during the evolution of experimental cholestatic liver diseaseQ46389248
Inhibition of Endocannabinoid Degradation Improves Outcomes from Mild Traumatic Brain Injury: A Mechanistic Role for Synaptic HyperexcitabilityQ46546882
The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokinesQ46859038
CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC/MS) in the rat hypothalamusQ46871279
A cannabinoid type 2 receptor agonist attenuates blood–brain barrier damage and neurodegeneration in a murine model of traumatic brain injuryQ47965888
Accumulation of amyloid beta and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig.Q48105099
Acute lung injury is an independent risk factor for brain hypoxia after severe traumatic brain injury.Q48121266
Guidelines for the management of severe traumatic brain injury. VIII. Intracranial pressure thresholdsQ48163500
Guidelines for the management of severe traumatic brain injury. VI. Indications for intracranial pressure monitoringQ48163517
Guidelines for the management of severe traumatic brain injuryQ48163575
Magnesium sulfate for neuroprotection after traumatic brain injury: a randomised controlled trialQ48339039
The early critical phase of severe head injury: importance of apnea and dysfunctional respirationQ48348368
The facilitating and suppressing effects of delta 9-tetrahydrocannabinol on the rise in intrasynaptosomal Ca2+ concentration in ratsQ48469786
Sequential assessment of cerebral blood flow in diffuse brain injury by 123I-iodoamphetamine single-photon emission CTQ48509294
CB1 receptor antagonism prevents long-term hyperexcitability after head injury by regulation of dynorphin-KOR system and mGluR5 in rat hippocampusQ48694375
The biphasic opening of the blood-brain barrier in the cortex and hippocampus after traumatic brain injury in ratsQ48726066
Cerebral blood flow as a predictor of outcome following traumatic brain injuryQ48742919
Cannabidiol-treated rats exhibited higher motor score after cryogenic spinal cord injuryQ48900936
Pre- and post-conditioning treatment with an ultra-low dose of Δ9-tetrahydrocannabinol (THC) protects against pentylenetetrazole (PTZ)-induced cognitive damageQ51020105
Voltage-gated sodium (NaV) channel blockade by plant cannabinoids does not confer anticonvulsant effects per se.Q51749647
Extent of microstructural white matter injury in postconcussive syndrome correlates with impaired cognitive reaction time: a 3T diffusion tensor imaging study of mild traumatic brain injuryQ51893033
Long-Term Consequences of Severe Closed Head Injury on Episodic MemoryQ52015300
Long-term effect of HU-211, a novel non-competitive NMDA antagonist, on motor and memory functions after closed head injury in the rat.Q52209491
Neurogenic pulmonary edema. Pathogenesis, clinical picture and therapyQ54145722
Synthetic cannabinoids.Q55601191
CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytesQ24649936
A2A receptors in inflammation and injury: lessons learned from transgenic animalsQ24652486
Human cannabinoid pharmacokineticsQ24652736
The orphan receptor GPR55 is a novel cannabinoid receptorQ24670137
Is posttraumatic epilepsy the best model of posttraumatic epilepsy?Q24682111
Hemopressin is an inverse agonist of CB1 cannabinoid receptorsQ24683759
Chemical Probes of Endocannabinoid MetabolismQ26863202
Pathophysiology and neuroprotection of global and focal perinatal brain injury: lessons from animal modelsQ27000069
Chronic Posttraumatic Epilepsy following Neocortical Undercut Lesion in MiceQ27335980
Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory PainQ27655121
CB1 cannabinoid receptors and on-demand defense against excitotoxicityQ28207143
Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damageQ28214799
Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptorQ28218654
Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonistQ28262546
Platelet‐ and macrophage‐derived endogenous cannabinoids are involved in endotoxin‐induced hypotensionQ28279865
Phytocannabinoids beyond the Cannabis plant - do they exist?Q28286497
2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brainQ28290395
Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptorsQ28292914
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amidesQ28295481
Molecular characterization of a peripheral receptor for cannabinoidsQ28298338
The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1)Q28343961
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamideQ28370516
Monoacylglycerol lipase (MAGL) inhibition attenuates acute lung injury in miceQ28534648
TRPV1 activation results in disruption of the blood-brain barrier in the ratQ28577575
Isolation and structure of a brain constituent that binds to the cannabinoid receptorQ29547476
The epidemiology and impact of traumatic brain injury: a brief overviewQ29615639
Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic studyQ29615905
Determination and characterization of a cannabinoid receptor in rat brainQ29618888
Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cordQ29619388
Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo.Q30492114
Safety and tolerability of cyclosporin a in severe traumatic brain injury patients: results from a prospective randomized trialQ33666525
The palmitoylethanolamide and oleamide enigmas : are these two fatty acid amides cannabimimetic?Q33724186
Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerolQ33900859
Endocannabinoids and vascular function.Q33952765
An endogenous cannabinoid (2-AG) is neuroprotective after brain injuryQ34093755
Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levelsQ36995471
Using a cost-benefit analysis to estimate outcomes of a clinical treatment guideline: testing theBrain Trauma Foundation guidelines for the treatment of severe traumatic brain injuryQ37062826
Targeting the endocannabinoid system: to enhance or reduce?Q37150745
Diglyceride lipase: a pathway for arachidonate release from human plateletsQ37336055
Production and physiological actions of anandamide in the vasculature of the rat kidney.Q37372676
Complications of decompressive craniectomy for traumatic brain injuryQ37503188
Neuropsychiatric Symptom Modeling in Male and Female C57BL/6J Mice after Experimental Traumatic Brain InjuryQ37649738
Experimental models for analysis of oligodendrocyte pathophysiology in strokeQ37691262
Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease?Q37691554
The epidemiology of traumatic brain injuryQ37710314
Acute management of acquired brain injury part II: an evidence-based review of pharmacological interventionsQ37727119
150 years of treating severe traumatic brain injury: a systematic review of progress in mortalityQ37730854
Supply and demand for endocannabinoidsQ37867227
Blood-brain barrier pathophysiology in traumatic brain injuryQ37980746
The Endocannabinoid System and the BrainQ38026949
The role of markers of inflammation in traumatic brain injury.Q38086443
Research progress in traumatic brain penumbraQ38211502
Effect of marijuana use on outcomes in traumatic brain injuryQ38255185
The Role of the Brain's Endocannabinoid System in Pain and Its Modulation by StressQ38659962
What are the disruptive symptoms of behavioral disorders after traumatic brain injury? A systematic review leading to recommendations for good practicesQ38697168
Use of magnesium in traumatic brain injuryQ34096651
CB2: a cannabinoid receptor with an identity crisisQ34098185
CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy modelQ34098258
Brain injury: the pathophysiology of the first hours.'Talk and Die revisited'.Q34355155
Moving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids.Q34373631
Mechanical strain injury increases intracellular sodium and reverses Na+/Ca2+ exchange in cortical astrocytesQ34374927
Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trialQ34477439
Synthetic CannabinoidsQ34483121
Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppressionQ34651059
The major central endocannabinoid directly acts at GABA A receptorsQ34660573
Cannabinoid receptors and their ligandsQ34673022
Endocannabinoid structure-activity relationships for interaction at the cannabinoid receptorsQ34673044
The endogenous fatty acid amide, palmitoylethanolamide, has anti-allodynic and anti-hyperalgesic effects in a murine model of neuropathic pain: involvement of CB(1), TRPV1 and PPARgamma receptors and neurotrophic factorsQ34792462
Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biologyQ34952213
Detection of behavioral alterations and learning deficits in mice lacking synaptophysin.Q34977739
Ischemic tolerance and endogenous neuroprotectionQ35126696
Endocannabinoid degradation inhibition improves neurobehavioral function, blood-brain barrier integrity, and neuroinflammation following mild traumatic brain injuryQ35143425
Inhibition of monoacylglycerol lipase prevents chronic traumatic encephalopathy-like neuropathology in a mouse model of repetitive mild closed head injury.Q35143497
The dual neuroprotective–neurotoxic profile of cannabinoid drugsQ35193273
Similarities and differences in spatial learning and object recognition between young male C57Bl/6J mice and Sprague-Dawley ratsQ35275747
A mouse model of blast-induced mild traumatic brain injury.Q35449811
The neurophysiology of brain injuryQ35620865
The fatty acid amide hydrolase inhibitor PF-3845 promotes neuronal survival, attenuates inflammation and improves functional recovery in mice with traumatic brain injuryQ35624344
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammationQ35645037
Cell death mechanisms following traumatic brain injuryQ35802485
An integrated approach to prevent and treat respiratory failure in brain-injured patientsQ36014168
Oxidative stress in the brain: novel cellular targets that govern survival during neurodegenerative diseaseQ36121400
The effect of moderate to severe traumatic brain injury (TBI) on different aspects of memory: a selective reviewQ36278289
Endocannabinoid regulation of nausea is mediated by 2-arachidonoylglycerol (2-AG) in the rat visceral insular cortexQ36421863
Mechanisms of CB1 receptor signaling: endocannabinoid modulation of synaptic strength.Q36434427
Cerebral preconditioning and ischaemic toleranceQ36484538
Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factorsQ36676002
Selective Inhibition of Alpha/Beta-Hydrolase Domain 6 Attenuates Neurodegeneration, Alleviates Blood Brain Barrier Breakdown, and Improves Functional Recovery in a Mouse Model of Traumatic Brain InjuryQ36795890
P921main subjecttraumatic brain injuryQ1995526
endocannabinoidsQ10483908
P304page(s)69
P577publication date2017-02-17
P1433published inFrontiers in PharmacologyQ2681208
P1476titleEndocannabinoids: A Promising Impact for Traumatic Brain Injury
P478volume8

Reverse relations

cites work (P2860)
Q89546933Cannabis Use and Sport: A Systematic Review
Q90259463Cannabis in the Treatment of Traumatic Brain Injury: A Primer for Clinicians
Q57177300Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse Brain
Q101051220Conformational gating, dynamics and allostery in human monoacylglycerol lipase
Q38747752Elucidating opportunities and pitfalls in the treatment of experimental traumatic brain injury to optimize and facilitate clinical translation.
Q52583978INSIGHT ON THE IMPACT OF ENDOCANNABINOID SYSTEM IN CANCER: A REVIEW.
Q99350059Low brain endocannabinoids associated with persistent non-goal directed nighttime hyperactivity after traumatic brain injury in mice
Q89945819Medical Cannabis Reduced Agitation in Acquired Brain Injury: A Case Study
Q58102489Medical Use of Cannabinoids
Q96576962Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction
Q89579808Neuroprotection Following Concussion: The Potential Role for Cannabidiol
Q57157638Neurotransmitter changes after traumatic brain injury: an update for new treatment strategies
Q64108699Oral Cannabidiol Prevents Allodynia and Neurological Dysfunctions in a Mouse Model of Mild Traumatic Brain Injury
Q55439675Review of the neurological benefits of phytocannabinoids.
Q99553751Understanding Cannabis-Based Therapeutics in Sports Medicine

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