The major central endocannabinoid directly acts at GABA(A) receptors

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The major central endocannabinoid directly acts at GABA(A) receptors is …
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scholarly articleQ13442814

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P819ADS bibcode2011PNAS..10818150S
P356DOI10.1073/PNAS.1113444108
P932PMC publication ID3207709
P698PubMed publication ID22025726
P5875ResearchGate publication ID51743809

P50authorTrevor G SmartQ64684772
P2093author name stringAndreas Zimmer
Jürg Gertsch
Erwin Sigel
Roland Baur
Ildiko Rácz
Janine Marazzi
P2860cites workSelective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effectsQ24569799
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Presynaptic GABAergic control of the locomotor drive in the isolated spinal cord of neonatal ratsQ48272892
2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptorQ24620096
Comparison of the enzymatic stability and intraocular pressure effects of 2-arachidonylglycerol and noladin ether, a novel putative endocannabinoidQ28204739
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Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptorsQ29616809
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Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolismQ33840797
GABA(A)R plasticity during pregnancy: relevance to postpartum depressionQ33872187
Distinct endocannabinoid control of GABA release at perisomatic and dendritic synapses in the hippocampusQ33996513
Subunit composition, distribution and function of GABA(A) receptor subtypesQ34143787
Positioning of the alpha-subunit isoforms confers a functional signature to gamma-aminobutyric acid type A receptors.Q34337736
Ovarian cycle-linked changes in GABA(A) receptors mediating tonic inhibition alter seizure susceptibility and anxietyQ34419058
An endocannabinoid mechanism for stress-induced analgesia.Q34428429
Comparative models of GABAA receptor extracellular and transmembrane domains: important insights in pharmacology and function.Q34443416
Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sitesQ34582058
The endocannabinoid system and painQ34612917
Cannabinoid receptors: where they are and what they do.Q34772274
Diversity of inhibitory neurotransmission through GABA(A) receptorsQ35872326
Techniques: Use of concatenated subunits for the study of ligand-gated ion channels.Q35960346
The cannabinoid CB1 receptor antagonists rimonabant (SR141716) and AM251 directly potentiate GABA(A) receptorsQ36176472
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alpha1beta2delta, a silent GABAA receptor: recruitment by tracazolate and neurosteroidsQ36495131
Targeting the endocannabinoid system: to enhance or reduce?Q37150745
Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia.Q37216017
Pharmacological and therapeutic secrets of plant and brain (endo)cannabinoidsQ37262976
An introduction to the endocannabinoid system: from the early to the latest conceptsQ37414543
The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitationQ37532968
GABAA receptor channelsQ40389943
Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes.Q40417870
Unanticipated structural and functional properties of delta-subunit-containing GABAA receptorsQ42224990
A novel allosteric modulatory site on the GABAA receptor beta subunitQ42285400
Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease modelsQ42508054
Use of concatamers to study GABAA receptor architecture and function: application to delta-subunit-containing receptors and possible pitfallsQ43243508
Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice.Q43594220
Properties of single sodium channels translated by Xenopus oocytes after injection with messenger ribonucleic acidQ44719504
P433issue44
P407language of work or nameEnglishQ1860
P921main subjectendocannabinoidsQ10483908
P304page(s)18150-18155
P577publication date2011-10-24
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleThe major central endocannabinoid directly acts at GABA(A) receptors
P478volume108

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