Increased cortical lesion load and intrathecal inflammation is associated with oligoclonal bands in multiple sclerosis patients: a combined CSF and MRI study.

scientific article published on 21 February 2017

Increased cortical lesion load and intrathecal inflammation is associated with oligoclonal bands in multiple sclerosis patients: a combined CSF and MRI study. is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1083854045
P356DOI10.1186/S12974-017-0812-Y
P932PMC publication ID5319028
P698PubMed publication ID28222766

P50authorMaria Donata BenedettiQ51041139
Stefania RossiQ55835206
Marco PitteriQ48879573
P2093author name stringRichard Reynolds
Francesco Facchiano
Massimiliano Calabrese
Gabriele Farina
Salvatore Monaco
Roberta Magliozzi
Alberto Gajofatto
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Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosisQ48949792
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Myelin-laden macrophages are anti-inflammatory, consistent with foam cells in multiple sclerosis.Q54626145
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Peripheral B cell depletion and central proinflammatory cytokine reduction following repeated intrathecal administration of rituximab in progressive Multiple SclerosisQ61230854
CSF oligoclonal band patterns reveal disease heterogeneity in multiple sclerosisQ28244975
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MRI correlates of cognitive dysfunction in multiple sclerosis patients.Q30599649
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Gadolinium-based MRI characterization of leptomeningeal inflammation in multiple sclerosisQ34472457
Biomarkers of inflammation and axonal degeneration/damage in patients with newly diagnosed multiple sclerosis: contributions of the soluble CD163 CSF/serum ratio to a biomarker panelQ35364112
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Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation statusQ36722852
Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis.Q37285430
Cerebrospinal fluid oligoclonal bands in multiple sclerosis and clinically isolated syndromes: a meta-analysis of prevalence, prognosis and effect of latitudeQ38083645
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The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain.Q38621895
Cerebrospinal fluid markers reveal intrathecal inflammation in progressive multiple sclerosis.Q39025444
Parenchymal accumulation of CD163+ macrophages/microglia in multiple sclerosis brainsQ39511165
Proteolytic shedding of the macrophage scavenger receptor CD163 in multiple sclerosisQ40126243
AN ELECTROPHORETIC STUDY OF THE PROTEIN COMPONENTS IN CEREBROSPINAL FLUID AND THEIR RELATIONSHIP TO THE SERUM PROTEINS.Q40973713
Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4.Q41040137
A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis.Q42847184
Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS.Q43227358
B cells undergo unique compartmentalized redistribution in multiple sclerosisQ44463732
BAFF maintains T-cell survival by inducing OPN expression in B cellsQ44657459
Consensus recommendations for MS cortical lesion scoring using double inversion recovery MRI.Q45191165
Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in the subarachnoid space of MOG-immunized ratsQ45799560
Lipid microarrays identify key mediators of autoimmune brain inflammationQ46845275
Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis.Q47357498
Axonal pathology in multiple sclerosis. A historical noteQ48093198
Cerebrospinal fluid CXCL13 in clinically isolated syndrome patients: Association with oligoclonal IgM bands and prediction of Multiple Sclerosis diagnosisQ48162212
Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology.Q48200750
The Rao's Brief Repeatable Battery and Stroop Test: normative values with age, education and gender corrections in an Italian populationQ48293543
Cortical lesion load associates with progression of disability in multiple sclerosis.Q48336159
Expression of B-cell-attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphomaQ48462130
Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitmentQ48701331
P433issue1
P921main subjectmultiple sclerosisQ8277
P304page(s)40
P577publication date2017-02-21
P1433published inJournal of NeuroinflammationQ15716679
P1476titleIncreased cortical lesion load and intrathecal inflammation is associated with oligoclonal bands in multiple sclerosis patients: a combined CSF and MRI study
P478volume14

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cites work (P2860)
Q49686544A new enzyme-linked immunosorbent assay for neurofilament light in cerebrospinal fluid: analytical validation and clinical evaluation.
Q98463732Advanced MRI features in relapsing multiple sclerosis patients with and without CSF oligoclonal IgG bands
Q89531252Association of intrathecal pleocytosis and IgG synthesis with axonal damage in early MS
Q33841113Differential contribution of immune effector mechanisms to cortical demyelination in multiple sclerosis
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Q92106211Immunity in Gilles de la Tourette-Syndrome: Results From a Cerebrospinal Fluid Study
Q90313485Increase of CSF inflammatory profile in a case of highly active multiple sclerosis
Q64266133MRI phenotypes in MS: Longitudinal changes and miRNA signatures
Q89830634Oligoclonal IgG antibodies in multiple sclerosis target patient-specific peptides
Q90479562Wide Cytokine Analysis in Cerebrospinal Fluid at Diagnosis Identified CCL-3 as a Possible Prognostic Factor for Multiple Sclerosis

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