Early human embryos are naturally aneuploid-can that be corrected?

scientific article

Early human embryos are naturally aneuploid-can that be corrected? is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1007/S10815-016-0845-7
P932PMC publication ID5330987
P698PubMed publication ID27900612

P50authorAnn A. KiesslingQ7508
P2093author name stringAmy Lee
P2860cites workNIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressorQ24338837
NIRF/UHRF2 occupies a central position in the cell cycle network and allows coupling with the epigenetic landscapeQ26851503
Human embryonic stem cell lines derived from single blastomeresQ28259674
Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expressionQ30545439
Genome-wide microarray evidence that 8-cell human blastomeres over-express cell cycle drivers and under-express checkpointsQ33548383
Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosityQ33743993
SNP microarray-based 24 chromosome aneuploidy screening demonstrates that cleavage-stage FISH poorly predicts aneuploidy in embryos that develop to morphologically normal blastocystsQ34007983
SNP microarray-based 24 chromosome aneuploidy screening is significantly more consistent than FISHQ34007989
Preimplantation genetic screening: a systematic review and meta-analysis of RCTsQ34181388
Chromosomal mosaicism in human preimplantation embryos: a systematic reviewQ34181395
Retinoblastoma: Clues to Human OncogenesisQ34255360
Preimplantation genetic diagnosis increases the implantation rate in human in vitro fertilization by avoiding the transfer of chromosomally abnormal embryos.Q50915846
Development and validation of a next-generation sequencing-based protocol for 24-chromosome aneuploidy screening of embryos.Q53063194
Clinical significance of the parental origin of the X chromosome in turner syndrome.Q53580807
Biopsy of human preimplantation embryos and sexing by DNA amplification.Q55057776
Treatment-related chromosome abnormalities in human embryosQ57779469
Human preimplantation development in vitro is not adversely affected by biopsy at the 8-cell stageQ68625246
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Gene amplification proceeds by a chromosome copy mechanismQ70346502
A cytogenetic study of 1000 spontaneous abortionsQ71028931
Assessment of polyploidy in human morulae and blastocysts using co-culture and fluorescent in-situ hybridizationQ72865717
The four blastomeres of a 4-cell stage human embryo are able to develop individually into blastocysts with inner cell mass and trophectodermQ81336074
Molecular origin of mitotic aneuploidies in preimplantation embryosQ34286611
Expression and potential function of the c-mos proto-oncogene in human eggsQ34337989
Molecular karyotyping of human single sperm by array- comparative genomic hybridizationQ34658671
Development and DNA polymerase activities in cultured preimplantation mouse embryos: comparison with embryos developed in vivoQ34807866
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The parental origin of the single X chromosome in Turner syndrome: lack of correlation with parental age or clinical phenotypeQ35196399
Meiotic origins of maternal age-related aneuploidyQ35855863
CircaDB: a database of mammalian circadian gene expression profilesQ36491476
Microarray Analyses Reveal Marked Differences in Growth Factor and Receptor Expression Between 8-Cell Human Embryos and Pluripotent Stem CellsQ36521760
Preimplantation genetic testing: a Practice Committee opinionQ36975085
Meiotic errors in human oogenesis and spermatogenesisQ37138710
Small molecule aurora kinases inhibitors.Q37515709
Lack of cell cycle checkpoints in human cleavage stage embryos revealed by a clonal pattern of chromosomal mosaicism analysed by sequential multicolour FISH.Q38495536
Mammalian pre-implantation chromosomal instability: species comparison, evolutionary considerations, and pathological correlations.Q38586272
Preimplantation genetic testing for aneuploidy: what technology should you use and what are the differences?Q38864772
The dormant and the fully competent oocyte: comparing the transcriptome of human oocytes from primordial follicles and in metaphase II.Q39433183
The protovirus hypothesis: speculations on the significance of RNA-directed DNA synthesis for normal development and for carcinogenesisQ41519885
Live birth outcome with trophectoderm biopsy, blastocyst vitrification, and single-nucleotide polymorphism microarray-based comprehensive chromosome screening in infertile patientsQ41607344
Dual fluorescent in situ hybridisation for simultaneous detection of X and Y chromosome-specific probes for the sexing of human preimplantation embryonic nucleiQ42136601
Derivation and differentiation of haploid human embryonic stem cellsQ42828835
In vitro fertilization with single euploid blastocyst transfer: a randomized controlled trialQ44232985
Cyclin A1/Cdk2 is sufficient but not required for the induction of apoptosis in early Xenopus laevis embryosQ44923231
Obstetrical and neonatal outcomes from the BEST Trial: single embryo transfer with aneuploidy screening improves outcomes after in vitro fertilization without compromising delivery ratesQ45710307
Comprehensive chromosome screening is highly predictive of the reproductive potential of human embryos: a prospective, blinded, nonselection studyQ46879263
Blastocyst biopsy with comprehensive chromosome screening and fresh embryo transfer significantly increases in vitro fertilization implantation and delivery rates: a randomized controlled trialQ48623792
Chromosomal aneuploidy in embryos conceived with unstimulated cycle IVF.Q48744843
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P921main subjectgenetic variationQ349856
meiosisQ16424695
biomedical investigative techniqueQ66648976
P304page(s)15-21
P577publication date2016-11-29
2017-01-01
P1433published inJournal of Assisted Reproduction and GeneticsQ15755113
P1476titleEarly human embryos are naturally aneuploid-can that be corrected?
P478volume34

Reverse relations

cites work (P2860)
Q33612541A single trophectoderm biopsy at blastocyst stage is mathematically unable to determine embryo ploidy accurately enough for clinical use
Q90347459Analysis of a Preimplantation Genetic Test for Aneuploidies in Embryos from Colombian Couples: A Report of Cases
Q91620892Human germline genome editing
Q90291605Meddling with new technologies or amending an embryos' potential
Q38689280Mosaicism in Preimplantation Human Embryos: When Chromosomal Abnormalities Are the Norm
Q55323049Understanding aneuploidy in cancer through the lens of system inheritance, fuzzy inheritance and emergence of new genome systems.