Proteomic profiling of x-linked muscular dystrophy

scientific article published on December 2009

Proteomic profiling of x-linked muscular dystrophy is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/S10974-009-9197-6
P698PubMed publication ID20082121

P2093author name stringKay Ohlendieck
Caroline Lewis
Steven Carberry
P2860cites workCurrent two-dimensional electrophoresis technology for proteomicsQ22252855
Glucocorticoid corticosteroids for Duchenne muscular dystrophyQ24242199
Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscleQ24308714
Gene expression comparison of biopsies from Duchenne muscular dystrophy (DMD) and normal skeletal muscleQ24538577
Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept studyQ24643018
Muscle regeneration in dystrophin-deficient mdx mice studied by gene expression profilingQ24815340
Inhibitory control over Ca(2+) sparks via mechanosensitive channels is disrupted in dystrophin deficient muscle but restored by mini-dystrophin expressionQ27438151
The complete sequence of dystrophin predicts a rod-shaped cytoskeletal proteinQ28118471
The human plasma proteome: history, character, and diagnostic prospectsQ28218148
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Matrix-Assisted Laser Desorption Ionization Mass Spectrometry: Applications in Peptide and Protein CharacterizationQ30417385
The human serum proteome: display of nearly 3700 chromatographically separated protein spots on two-dimensional electrophoresis gels and identification of 325 distinct proteinsQ30966472
Proteomic analysis of mdx skeletal muscle: Great reduction of adenylate kinase 1 expression and enzymatic activityQ31027117
Differential expression of the skeletal muscle proteome in mdx mice at different ages.Q33205614
Reduced expression of regucalcin in young and aged mdx diaphragm indicates abnormal cytosolic calcium handling in dystrophin-deficient muscle.Q33234154
Mass spectrometry and protein analysisQ33239890
Proteome analysis of the dystrophin-deficient MDX diaphragm reveals a drastic increase in the heat shock protein cvHSP.Q33249876
Mass spectrometry technologies for proteomicsQ33268106
Serum protein profiling in mice: identification of Factor XIIIa as a potential biomarker for muscular dystrophyQ33328023
Proteomic profiling of antisense-induced exon skipping reveals reversal of pathobiochemical abnormalities in dystrophic mdx diaphragm.Q33398588
Dystroglycan inside and out.Q33744965
Animal models for muscular dystrophy: valuable tools for the development of therapiesQ34045919
Isolation of candidate cDNAs for portions of the Duchenne muscular dystrophy geneQ34190227
Evolution of the alpha-crystallin/small heat-shock protein familyQ34361727
Limb-girdle muscular dystrophiesQ34573570
Intrinsic laryngeal muscles are spared from myonecrosis in the mdx mouse model of Duchenne muscular dystrophyQ34586999
Proteomic analysis of striated muscleQ34642389
Is proteomics the new genomics?Q34662107
Muscular dystrophy into the new millenniumQ34682745
Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models.Q34699458
Elevated subsarcolemmal Ca2+ in mdx mouse skeletal muscle fibers detected with Ca2+-activated K+ channels.Q35700706
The development of the DIGE system: 2D fluorescence difference gel analysis technologyQ36131099
Molecular and cell biology of the sarcoglycan complexQ36152977
Expression profiling in the muscular dystrophies: identification of novel aspects of molecular pathophysiologyQ36360412
Two-dimensional gel electrophoresis as tool for proteomics studies in combination with protein identification by mass spectrometryQ36577758
Dystrobrevins in muscle and non-muscle tissues.Q36717600
Dystrophic skeletal muscle fibers display alterations at the level of calcium microdomainsQ36936452
Emerging strategies for cell and gene therapy of the muscular dystrophiesQ36960845
Biology of the striated muscle dystrophin-glycoprotein complexQ37085050
The therapeutic potential of antisense-mediated exon skippingQ37127482
Applications of metabolomics and proteomics to the mdx mouse model of Duchenne muscular dystrophy: lessons from downstream of the transcriptomeQ37149236
Complementary methods to assist subcellular fractionation in organellar proteomicsQ37257664
Exon skipping and Duchenne muscular dystrophy: hope, hype and how feasible?Q37313819
Malformed mdx myofibers have normal cytoskeletal architecture yet altered EC coupling and stress-induced Ca2+ signalingQ37338902
Power and limitations of electrophoretic separations in proteomics strategies.Q37346251
Proteomics of skeletal muscle agingQ37380758
Exon-skipping therapy for Duchenne muscular dystrophyQ37503677
Diagnosis and new treatments in muscular dystrophiesQ37521427
Proteomic profiling of animal models mimicking skeletal muscle disordersQ37817162
Detailed analysis of the repeat domain of dystrophin reveals four potential hinge segments that may confer flexibilityQ39260422
Two-dimensional difference gel electrophoresisQ39792303
Three muscular dystrophies: loss of cytoskeleton-extracellular matrix linkage.Q40612428
The structural and functional diversity of dystrophinQ40644356
Chaperone activity of alpha-crystallins modulates intermediate filament assembly.Q40790972
Towards an understanding of the dystrophin-glycoprotein complex: linkage between the extracellular matrix and the membrane cytoskeleton in muscle fibers.Q40958054
Dystrophies and heart disease.Q41550717
Calcium influx through calcium leak channels is responsible for the elevated levels of calcium-dependent proteolysis in dystrophic myotubesQ41726707
Drastic reduction of sarcalumenin in Dp427 (dystrophin of 427 kDa)-deficient fibres indicates that abnormal calcium handling plays a key role in muscular dystrophy.Q41823396
Involvement of TRPC in the abnormal calcium influx observed in dystrophic (mdx) mouse skeletal muscle fibersQ41882302
Structural and functional analysis of the sarcoglycan-sarcospan subcomplexQ42712728
Dystrophin-glycoprotein complex is highly enriched in isolated skeletal muscle sarcolemmaQ43107646
Drastic reduction of calsequestrin-like proteins and impaired calcium binding in dystrophic mdx muscleQ43858043
Sarcoplasmic reticulum function in slow- and fast-twitch skeletal muscles from mdx miceQ44113196
The action potential-evoked sarcoplasmic reticulum calcium release is impaired in mdx mouse muscle fibresQ44788698
Myoblast survival enhancement and transplantation success improvement by heat-shock treatment in mdx miceQ44913842
Subproteomics analysis of Ca+-binding proteins demonstrates decreased calsequestrin expression in dystrophic mouse skeletal muscleQ45063439
Proteolysis results in altered leak channel kinetics and elevated free calcium in mdx muscle.Q45982332
A combined metabolomic and proteomic investigation of the effects of a failure to express dystrophin in the mouse heartQ46043712
Diltiazem and verapamil protect dystrophin-deficient muscle fibers of MDX mice from degeneration: a potential role in calcium buffering and sarcolemmal stability.Q46161936
Regulation of cell proliferation by fast Myosin light chain 1 in myoblasts derived from extraocular muscle, diaphragm and gastrocnemiusQ46288810
Insulin-like growth factor-I analogue protects muscles of dystrophic mdx mice from contraction-mediated damageQ46528995
TRPC1 binds to caveolin-3 and is regulated by Src kinase - role in Duchenne muscular dystrophyQ46547351
Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathologyQ46917397
Comparative proteomic profile of rat sciatic nerve and gastrocnemius muscle tissues in ageing by 2-D DIGE.Q51743242
Sarcoplasmic-endoplasmic-reticulum Ca2+-ATPase and calsequestrin are overexpressed in spared intrinsic laryngeal muscles of dystrophin-deficient mdx mice.Q51757790
Expression of heat-shock/stress proteins in Duchenne muscular dystrophy.Q52211391
Distal mdx muscle groups exhibiting up-regulation of utrophin and rescue of dystrophin-associated glycoproteins exemplify a protected phenotype in muscular dystrophy.Q53969078
PROTEOMICS (article)Q57374628
The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophyQ59051261
Deficiency of a glycoprotein component of the dystrophin complex in dystrophic muscleQ59089242
Ultrastructural localization of dystrophin in human muscle by using gold immunolabellingQ68091120
Dystrophin-related protein is localized to neuromuscular junctions of adult skeletal muscleQ68255626
The mutant mdx: inherited myopathy in the mouse. Morphological studies of nerves, muscles and end-platesQ68984568
The molecular basis of muscular dystrophy in the mdx mouse: a point mutationQ69514522
Dystrophin constitutes 5% of membrane cytoskeleton in skeletal muscleQ70177916
Duchenne muscular dystrophy: deficiency of dystrophin-associated proteins in the sarcolemmaQ70651010
Comparative analysis of Dp427-deficient mdx tissues shows that the milder dystrophic phenotype of extraocular and toe muscle fibres is associated with a persistent expression of beta-dystroglycanQ73512517
The muscular dystrophiesQ77731754
Transient receptor potential cation channels in normal and dystrophic mdx muscleQ81338799
Laryngeal muscles are spared in the dystrophin deficient mdx mouseQ81343725
Analysis of gene expression differences between utrophin/dystrophin-deficient vs mdx skeletal muscles reveals a specific upregulation of slow muscle genes in limb musclesQ82770599
Difference gel electrophoresisQ84046993
P433issue7-8
P304page(s)267-269
P577publication date2009-12-01
P1433published inJournal of Muscle Research & Cell MotilityQ13739445
P1476titleProteomic profiling of x-linked muscular dystrophy
P478volume30

Reverse relations

cites work (P2860)
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Q36613670Proteomics reveals drastic increase of extracellular matrix proteins collagen and dermatopontin in the aged mdx diaphragm model of Duchenne muscular dystrophy
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