Ion channels or aquaporins as novel molecular targets in gastric cancer

scientific article published on 06 March 2017

Ion channels or aquaporins as novel molecular targets in gastric cancer is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1084251308
P356DOI10.1186/S12943-017-0622-Y
P932PMC publication ID5338097
P698PubMed publication ID28264681

P2093author name stringLi Sun
Shi Li
Ming Zeng
Hongqiang Wang
Hongxiang Huang
Jianling Xia
Qinghui Wu
P2860cites workAquaporin modulators: a patent review (2010-2015).Q51512961
miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway.Q53314337
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Angiogenic functions of voltage-gated Na+ Channels in human endothelial cells: modulation of vascular endothelial growth factor (VEGF) signalingQ34947687
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Upregulation of the inwardly rectifying potassium channel Kir2.1 (KCNJ2) modulates multidrug resistance of small-cell lung cancer under the regulation of miR-7 and the Ras/MAPK pathwayQ35215772
Chloride channel-3 promotes tumor metastasis by regulating membrane ruffling and is associated with poor survivalQ35273723
Inhibition of Calcium-Activated Chloride Channel ANO1/TMEM16A Suppresses Tumor Growth and Invasion in Human Lung CancerQ35754730
Silencing of voltage-gated potassium channel KV9.3 inhibits proliferation in human colon and lung carcinoma cellsQ35781525
TMEM16A overexpression contributes to tumor invasion and poor prognosis of human gastric cancer through TGF-β signalingQ35793867
Pharmacological blockade of aquaporin-1 water channel by AqB013 restricts migration and invasiveness of colon cancer cells and prevents endothelial tube formation in vitroQ35935029
Inhibition of SK4 Potassium Channels Suppresses Cell Proliferation, Migration and the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer CellsQ36001840
An emerging role for voltage-gated Na+ channels in cellular migration: regulation of central nervous system development and potentiation of invasive cancersQ36049612
Prognostic significance of the TREK-1 K2P potassium channels in prostate cancerQ36210906
Voltage-gated sodium channels and metastatic disease.Q36430239
Proteomic knowledge of human aquaporins.Q36624645
Atrial natriuretic peptide modulates the proliferation of human gastric cancer cells via KCNQ1 expressionQ37211790
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Aquaporin 3 facilitates chemoresistance in gastric cancer cells to cisplatin via autophagyQ37412002
Chloride intracellular channel 1 regulates colon cancer cell migration and invasion through ROS/ERK pathwayQ37602738
Aquaporins at a glanceQ37889001
The burden of stomach cancer in indigenous populations: a systematic review and global assessmentQ38155060
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Chloride intracellular channel 1 regulates migration and invasion in gastric cancer by triggering the ROS-mediated p38 MAPK signaling pathwayQ38544029
Role of TRP ion channels in cancer and tumorigenesis.Q38722167
Voltage-gated sodium channel Nav 1.7 promotes gastric cancer progression through MACC1-mediated upregulation of NHE1.Q38751561
Elevated Orai1 and STIM1 expressions upregulate MACC1 expression to promote tumor cell proliferation, metabolism, migration, and invasion in human gastric cancerQ38757267
The proliferation impairment induced by AQP3 deficiency is the result of glycerol uptake and metabolism inhibition in gastric cancer cellsQ38803582
Chloride intracellular channel 1 (CLIC1) is activated and functions as an oncogene in pancreatic cancerQ38881347
Aquaporin 3 promotes prostate cancer cell motility and invasion via extracellular signal-regulated kinase 1/2-mediated matrix metalloproteinase-3 secretionQ38927977
Cytosolic chloride ion is a key factor in lysosomal acidification and function of autophagy in human gastric cancer cellQ39005063
hERG1 channels regulate VEGF-A secretion in human gastric cancer: clinicopathological correlations and therapeutical implicationsQ39031966
Functional expression of the voltage-gated Na⁺-channel Nav1.7 is necessary for EGF-mediated invasion in human non-small cell lung cancer cellsQ39103592
miR-874 Inhibits cell proliferation, migration and invasion through targeting aquaporin-3 in gastric cancerQ39134990
Aquaporin-4 upregulated expression in glioma tissue is a reaction to glioma-associated edema induced by vascular endothelial growth factorQ39291094
TRPM7 is required for breast tumor cell metastasisQ39301061
Epidermal growth factor enhances MPC-83 pancreatic cancer cell migration through the upregulation of aquaporin 3.Q39324693
The role of transient receptor potential channel blockers in human gastric cancer cell viabilityQ39401052
PA28β regulates cell invasion of gastric cancer via modulating the expression of chloride intracellular channel 1.Q39427486
Human ether-à-go-go-related gene expression is essential for cisplatin to induce apoptosis in human gastric cancerQ39454149
ClC-3 is a main component of background chloride channels activated under isotonic conditions by autocrine ATP in nasopharyngeal carcinoma cells.Q39500264
Anti-proliferative effect of Kv1.3 blockers in A549 human lung adenocarcinoma in vitro and in vivoQ39630130
Involvement of Kv4.1 K(+) channels in gastric cancer cell proliferationQ39647050
Essential role of TRPC6 channels in G2/M phase transition and development of human glioma.Q39691899
Critical role of aquaporin-3 in the human epidermal growth factor-induced migration and proliferation in the human gastric adenocarcinoma cellsQ39719069
Role of cationic channel TRPV2 in promoting prostate cancer migration and progression to androgen resistanceQ39747572
Involvement of aquaporin-5 in differentiation of human gastric cancer cellsQ39865042
Orai1 and STIM1 are critical for breast tumor cell migration and metastasisQ39888627
Suppression of transient receptor potential melastatin 7 channel induces cell death in gastric cancerQ39912548
Activation of cell migration with fibroblast growth factor-2 requires calcium-sensitive potassium channelsQ40019515
Expression and significance of HERG protein in gastric cancerQ40067338
Insulin and insulin-like growth factor type-I up-regulate the vanilloid receptor-1 (TRPV1) in stably TRPV1-expressing SH-SY5Y neuroblastoma cellsQ40154211
TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells--Mechanisms behind a possible new "hot" cancer treatmentQ40172527
Nerve growth factor enhances voltage-gated Na+ channel activity and Transwell migration in Mat-LyLu rat prostate cancer cell lineQ40200194
The Biological Significance of Cell VolumeQ40486930
Correlation of hepatocyte growth factor-induced proliferation and calcium-activated potassium current in human gastric cancer cellsQ41066248
Ion channels in health and disease. 83rd Boehringer Ingelheim Fonds International Titisee ConferenceQ42724241
Knockdown of Inwardly Rectifying Potassium Channel Kir2.2 Suppresses Tumorigenesis by Inducing Reactive Oxygen Species–Mediated Cellular SenescenceQ42907409
Editorial: ion fluxes and cancerQ43813618
Increased migration and local invasion potential of SiHa cervical cancer cells expressing Aquaporin 8.Q43978684
c-Met upregulates aquaporin 3 expression in human gastric carcinoma cells via the ERK signalling pathwayQ44384406
Ion channels and transporters in cancer: pathophysiology, regulation, and clinical potentialQ44828886
Nav1.5 sodium channels in macrophages in multiple sclerosis lesions.Q45902330
Aquaporin 5 promotes the proliferation and migration of human gastric carcinoma cells.Q45923817
Blockade of TRPC6 channels induced G2/M phase arrest and suppressed growth in human gastric cancer cells.Q45926994
Critical role of TRPC6 channels in VEGF-mediated angiogenesisQ47942617
Overexpression of NaV 1.6 channels is associated with the invasion capacity of human cervical cancerQ48258918
Voltage-dependent potassium channels Kv1.3 and Kv1.5 in human cancerQ48373384
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P921main subjectaquaporinQ623090
stomach neoplasmQ4335552
ion channel complexQ62536
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)54
P577publication date2017-03-06
P1433published inMolecular CancerQ15724585
P1476titleIon channels or aquaporins as novel molecular targets in gastric cancer
P478volume16

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cites work (P2860)
Q47103599CLCA4 inhibits bladder cancer cell proliferation, migration, and invasion by suppressing the PI3K/AKT pathway
Q58736691Circular RNA: new star, new hope in cancer
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Q58720903Prediction of key genes and pathways involved in trastuzumab-resistant gastric cancer
Q55356248Significance of aquaporins' expression in the prognosis of gastric cancer.
Q59793511Water transport proteins–aquaporins (AQPs) in cancer biology
Q64899156hERG1 is involved in the pathophysiological process and inhibited by berberine in SKOV3 cells.

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