Association between STK11 Gene Polymorphisms and Coronary Artery Disease in Type 2 Diabetes in Han Population in China. (scientific article published on 28 February 2017)

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Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation

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APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function

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LKB1 in endothelial cells is required for angiogenesis and TGFbeta-mediated vascular smooth muscle cell recruitment.

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Adiponectin-induced endothelial nitric oxide synthase activation and nitric oxide production are mediated by APPL1 in endothelial cells.

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Diabetes and cardiovascular risk factors: the Framingham study

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An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls

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[Effect of BMSCs transplantation on cardiac function of diabetes mellitus rats]

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A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance

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Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation

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Detection of coronary artery stenoses by contrast-enhanced, retrospectively electrocardiographically-gated, multislice spiral computed tomography

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A single nucleotide polymorphism in STK11 influences insulin sensitivity and metformin efficacy in hyperinsulinemic girls with androgen excess.

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Ablation of LKB1 in the heart leads to energy deprivation and impaired cardiac function

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An APPL1-AMPK signaling axis mediates beneficial metabolic effects of adiponectin in the heart.

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Intron-mediated regulation of gene expression

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New roles for the LKB1-->AMPK pathway.

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Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKalpha2 but not AMPKalpha1.

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Improved myocardial perfusion in chronic diabetic mice by the up-regulation of pLKB1 and AMPK signaling.

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Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent pathways

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Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction

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The role of AMP-activated protein kinase in the cardiovascular system

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LKB1 loss of function studied in vivo

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Adiponectin: anti-inflammatory and cardioprotective effects

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eNOS activation mediated by AMPK after stimulation of endothelial cells with histamine or thrombin is dependent on LKB1.

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Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients