| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.3109/09537101003599549 |
| P698 | PubMed publication ID | 20201633 |
| P2093 | author name string | Marc F Hoylaerts | |
| Hu Hu | |||
| P2860 | cites work | P2X1 purinoceptor in human platelets. Molecular cloning and functional characterization after heterologous expression | Q24310679 |
| The ATP-gated P2X1 receptor plays a pivotal role in activation of aspirin-treated platelets by thrombin and epinephrine | Q24312716 | ||
| Proteomic and functional evidence for a P2X7 receptor signalling complex | Q24535912 | ||
| Functional expression and photoaffinity labeling of a cloned P2U purinergic receptor | Q24564431 | ||
| Crystal structure of the ATP-gated P2X(4) ion channel in the closed state | Q24657193 | ||
| A study of P2X1 receptor function in murine megakaryocytes and human platelets reveals synergy with P2Y receptors | Q24673329 | ||
| Functional rafts in cell membranes | Q27860768 | ||
| Role of CD39 (NTPDase-1) in thromboregulation, cerebroprotection, and cardioprotection | Q28174331 | ||
| Polar residues of the second transmembrane domain influence cation permeability of the ATP-gated P2X(2) receptor | Q28201447 | ||
| Primary and secondary agonists can use P2X(1) receptors as a major pathway to increase intracellular Ca(2+) in the human platelet | Q28221012 | ||
| Src kinase activity is regulated by the SHP-1 protein-tyrosine phosphatase | Q28246466 | ||
| Ectonucleotidases of CD39 Family Modulate Vascular Inflammation and Thrombosis in Transplantation | Q28314900 | ||
| Pharmacological characterization of the human P2Y11 receptor | Q28343735 | ||
| Antagonism by the suramin analogue NF279 on human P2X(1) and P2X(7) receptors | Q28369331 | ||
| Reduced vas deferens contraction and male infertility in mice lacking P2X1 receptors | Q28505454 | ||
| A role of the fast ATP-gated P2X1 cation channel in thrombosis of small arteries in vivo | Q28513773 | ||
| Disruption of lipid rafts inhibits P2X1 receptor-mediated currents and arterial vasoconstriction | Q28572480 | ||
| A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP | Q28573068 | ||
| P2X7 receptor mediated phosphorylation of p38MAP kinase in the hippocampus | Q28590060 | ||
| Interplay between P2Y(1), P2Y(12), and P2X(1) receptors in the activation of megakaryocyte cation influx currents by ADP: evidence that the primary megakaryocyte represents a fully functional model of platelet P2 receptor signaling | Q28591641 | ||
| Localization of the adhesion receptor glycoprotein Ib-IX-V complex to lipid rafts is required for platelet adhesion and activation | Q28629042 | ||
| Structure and function of sphingolipid- and cholesterol-rich membrane rafts | Q29618518 | ||
| NF449, a novel picomolar potency antagonist at human P2X1 receptors | Q30320633 | ||
| Inhibition of platelet functions and thrombosis through selective or nonselective inhibition of the platelet P2 receptors with increasing doses of NF449 [4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis-(carbonylimino)))tetrakis-benzene-1,3-di | Q30780555 | ||
| P2X1 stimulation promotes thrombin receptor-mediated platelet aggregation | Q33240895 | ||
| Functional and molecular diversity of purinergic ion channel receptors | Q33691550 | ||
| A natural dominant negative P2X1 receptor due to deletion of a single amino acid residue | Q33902239 | ||
| Pharmacology of cloned P2X receptors | Q33932194 | ||
| Agonists and antagonists acting at P2X receptors: selectivity profiles and functional implications | Q34101826 | ||
| Conserved cysteine residues in the extracellular loop of the human P2X(1) receptor form disulfide bonds and are involved in receptor trafficking to the cell surface | Q34111088 | ||
| The intracellular tyrosine residues of the ATP-gated P2X(1) ion channel are essential for its function | Q34140669 | ||
| P2X(1)-mediated activation of extracellular signal-regulated kinase 2 contributes to platelet secretion and aggregation induced by collagen | Q34150092 | ||
| Overexpression of the platelet P2X1 ion channel in transgenic mice generates a novel prothrombotic phenotype | Q34169675 | ||
| Quantification of ADP and ATP receptor expression in human platelets | Q34215566 | ||
| Lack of evidence for functional ADP-activated human P2X1 receptors supports a role for ATP during hemostasis and thrombosis | Q34220809 | ||
| PPADS, a novel functionally selective antagonist of P2 purinoceptor-mediated responses | Q34238447 | ||
| P2X1-mediated ERK2 Activation Amplifies the Collagen-induced Platelet Secretion by Enhancing Myosin Light Chain Kinase Activation | Q34263918 | ||
| Synaptic P2X receptors | Q34278097 | ||
| New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor | Q34292603 | ||
| Activation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X7-associated pore or channel formation. | Q35545223 | ||
| Molecular structure of P2X receptors | Q35743728 | ||
| Cysteine substitution mutants give structural insight and identify ATP binding and activation sites at P2X receptors | Q36166147 | ||
| Acidic amino acids impart enhanced Ca2+ permeability and flux in two members of the ATP-gated P2X receptor family | Q36295984 | ||
| Activation and Desensitization of the Recombinant P2X1 Receptor at Nanomolar ATP Concentrations | Q36412485 | ||
| The platelet ATP and ADP receptors | Q36412840 | ||
| Nucleotide receptor signaling in platelets | Q36632296 | ||
| Platelet P2 receptors: old and new targets for antithrombotic drugs | Q36691632 | ||
| Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human platelets | Q36895115 | ||
| P2X(1) receptor inhibition and soluble CD39 administration as novel approaches to widen the cardiovascular therapeutic window | Q37494937 | ||
| Ectodomain lysines and suramin block of P2X1 receptors | Q39944286 | ||
| On the role of the first transmembrane domain in cation permeability and flux of the ATP-gated P2X2 receptor | Q40042581 | ||
| P2X receptors bring new structure to ligand-gated ion channels | Q40402421 | ||
| Purinoceptors: are there families of P2X and P2Y purinoceptors? | Q40510363 | ||
| G-protein-coupled receptor regulation of P2X1 receptors does not involve direct channel phosphorylation | Q40555892 | ||
| Structure-activity relationships of analogues of NF449 confirm NF449 as the most potent and selective known P2X1 receptor antagonist | Q40568678 | ||
| Contribution of calcium ions to P2X channel responses. | Q40571393 | ||
| Thrombopoietin Enhances Rapid Current Responses Mediated by P2X1 Receptors on Megakaryocytic Cells in Culture | Q40618559 | ||
| Lipid rafts orchestrate signaling by the platelet receptor glycoprotein VI. | Q40751017 | ||
| Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors | Q40791305 | ||
| Amino acid residues involved in gating identified in the first membrane-spanning domain of the rat P2X(2) receptor | Q40816581 | ||
| Adenosine receptors: new opportunities for future drugs. | Q40849413 | ||
| A pyridoxine cyclic phosphate and its 6-azoaryl derivative selectively potentiate and antagonize activation of P2X1 receptors | Q40854824 | ||
| Direct modulation of P2X1 receptor-channels by the lipid phosphatidylinositol 4,5-bisphosphate | Q41025603 | ||
| Direct evidence for ATP release from non-adrenergic, non-cholinergic ("purinergic") nerves in the guinea-pig taenia coli and bladder | Q41040379 | ||
| Identification of amino acid residues contributing to the pore of a P2X receptor | Q41106961 | ||
| Characterisation of a recombinant P2Y purinoceptor | Q41268916 | ||
| Design and pharmacology of selective P2-purinoceptor antagonists | Q41455996 | ||
| ADP is not an agonist at P2X(1) receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets | Q41961496 | ||
| Diinosine pentaphosphate (IP5I) is a potent antagonist at recombinant rat P2X1 receptors. | Q42085394 | ||
| 2',3'-O-(2,4,6- trinitrophenyl) adenosine 5'-triphosphate (TNP-ATP)--a nanomolar affinity antagonist at rat mesenteric artery P2X receptor ion channels | Q42175834 | ||
| Diadenosine pentaphosphate is more potent than ATP at P2X receptors in isolated rat vagus nerve | Q43558611 | ||
| Novel structurally altered P(2X1) receptor is preferentially activated by adenosine diphosphate in platelets and megakaryocytic cells | Q43648017 | ||
| The role of histidine residues in modulation of the rat P2X(2) purinoceptor by zinc and pH. | Q43908338 | ||
| PPNDS is an agonist, not an antagonist, for the ATP receptor of Paramecium | Q44262875 | ||
| Concentration of rafts in platelet filopodia correlates with recruitment of c-Src and CD63 to these domains | Q44518762 | ||
| Mitogen-activated protein kinase and caspase signaling pathways are required for P2X7 receptor (P2X7R)-induced pore formation in human THP-1 cells | Q44666463 | ||
| Potentiation of platelet activation through the stimulation of P2X1 receptors | Q44693032 | ||
| ATP augments von Willebrand factor-dependent shear-induced platelet aggregation through Ca2+-calmodulin and myosin light chain kinase activation | Q44846697 | ||
| Profiling at recombinant homomeric and heteromeric rat P2X receptors identifies the suramin analogue NF449 as a highly potent P2X1 receptor antagonist | Q45274145 | ||
| P2X(1) receptor subunit contribution to gating revealed by a dominant negative PKC mutant | Q45713476 | ||
| Potentiation of P2X1 ATP-gated currents by 5-hydroxytryptamine 2A receptors involves diacylglycerol-dependent kinases and intracellular calcium | Q46549178 | ||
| The novel suramin analogue NF864 selectively blocks P2X1 receptors in human platelets with potency in the low nanomolar range | Q46699751 | ||
| Contribution of conserved glycine residues to ATP action at human P2X1 receptors: mutagenesis indicates that the glycine at position 250 is important for channel function | Q46762841 | ||
| Calcium permeability and block at homomeric and heteromeric P2X2 and P2X3 receptors, and P2X receptors in rat nodose neurones | Q47977257 | ||
| Benzoyl ATP is an antagonist of rat and human P2Y1 receptors and of platelet aggregation | Q48270190 | ||
| The novel pyridoxal-5'-phosphate derivative PPNDS potently antagonizes activation of P2X(1) receptors | Q48900353 | ||
| Pharmacological characterization of recombinant human and rat P2X receptor subtypes | Q48911279 | ||
| Potent inhibition by trivalent cations of ATP-gated channels | Q48958734 | ||
| Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation | Q50336029 | ||
| Contribution of P2X1 receptor intracellular basic residues to channel properties. | Q50644563 | ||
| P2X agonist BzATP interferes with amplex-red-coupled fluorescence assays. | Q50691929 | ||
| The suramin analogue NF279 is a novel and potent antagonist selective for the P2X(1) receptor. | Q50724270 | ||
| Differential sensitivity of human platelet P2X1 and P2Y1 receptors to disruption of lipid rafts. | Q52569376 | ||
| Lipid Rafts Facilitate the Interaction of PECAM-1 with the Glycoprotein VI-FcR γ-Chain Complex in Human Platelets | Q57372595 | ||
| P433 | issue | 3 | |
| P304 | page(s) | 153-166 | |
| P577 | publication date | 2010-01-01 | |
| P1433 | published in | Platelets | Q1573582 |
| P1476 | title | The P2X1 ion channel in platelet function | |
| P478 | volume | 21 |
| Q35122793 | Activation and regulation of purinergic P2X receptor channels |
| Q35278165 | Anti-platelet therapy: ADP receptor antagonists |
| Q26799623 | Blood cells: an historical account of the roles of purinergic signalling |
| Q34902163 | C-type lectin like receptor 2 (CLEC-2) signals independently of lipid raft microdomains in platelets |
| Q38091213 | Emerging roles of store-operated Ca²⁺ entry through STIM and ORAI proteins in immunity, hemostasis and cancer |
| Q24617046 | Molecular and functional properties of P2X receptors--recent progress and persisting challenges |
| Q44981820 | PKC inhibition markedly enhances Ca2+ signaling and phosphatidylserine exposure downstream of protease-activated receptor-1 but not protease-activated receptor-4 in human platelets |
| Q38095124 | Platelet biology: the role of shear |
| Q37807427 | Platelet physiology and antiplatelet agents |
| Q37157402 | Subtype-specific control of P2X receptor channel signaling by ATP and Mg2+. |
| Q40643519 | Using antibodies against P2Y and P2X receptors in purinergic signaling research |
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